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Term:
iduronate-2-sulfatase activity
(GO:0004423)
Annotations:
Rat: (1)
Mouse: (1)
Human: (1)
Chinchilla: (1)
Bonobo: (1)
Dog: (1)
Squirrel: (1)
Pig: (1)
Naked Mole-rat: (1)
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Parent Terms
Term With Siblings
Child Terms
sulfuric ester hydrolase activity
+
arylsulfatase activity
cellulose-polysulfatase activity
cerebroside-sulfatase activity
choline-sulfatase activity
chondro-4-sulfatase activity
chondro-6-sulfatase activity
D-lactate-2-sulfatase activity
disulfoglucosamine-6-sulfatase activity
glucuronate-2-sulfatase activity
glycosulfatase activity
iduronate-2-sulfatase activity
Catalysis of the hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin.
linear primary-alkylsulfatase activity
monomethyl-sulfatase activity
N-acetylgalactosamine-4-sulfatase activity
N-acetylgalactosamine-6-sulfatase activity
N-acetylglucosamine-6-sulfatase activity
N-sulfoglucosamine-3-sulfatase activity
steryl-sulfatase activity
Synonyms
Exact Synonyms:
iduronate-2-sulphatase activity
Broad Synonyms:
chondroitinsulfatase
Related Synonyms:
2-sulfo-L-iduronate 2-sulfatase activity ; L-iduronate 2-sulfate sulfatase activity ; L-iduronate-2-sulfate 2-sulfohydrolase activity ; L-idurono sulfate sulfatase activity ; L-iduronosulfatase activity ; iduronate sulfatase activity ; iduronate sulfate sulfatase activity ; iduronate-2-sulfate sulfatase activity ; iduronide-2-sulfate sulfatase activity ; idurono-2-sulfatase activity
Xrefs:
EC:3.1.6.13 ; MetaCyc:3.1.6.13-RXN ; Reactome:R-HSA-2262743 "Defective IDS does not hydrolyse dermatan sulfate (Chebi:63517 chain)" ; Reactome:R-HSA-9036046 "Defective IDS does not hydrolyse Heparan sulfate chain(5)" ; reactome:R-HSA-1678650 "IDS hydrolyses Heparan sulfate chain(5)" ; reactome:R-HSA-1793182 "IDS hydrolyses dermatan sulfate (Chebi:63517 chain)"
Definition Sources:
EC:3.1.6.13