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Term:
Parent Terms Term With Siblings Child Terms
DNA nucleotidylexotransferase activity  
DNA-directed DNA polymerase activity  
Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time.
RNA-directed DNA polymerase activity +   

Synonyms
Narrow Synonyms: DNA polymerase I ;   DNA polymerase II ;   DNA polymerase III ;   DNA polymerase V activity ;   DNA polymerase alpha ;   DNA polymerase beta ;   DNA polymerase gamma ;   Klenow fragment ;   Taq DNA polymerase ;   Taq Pol I
Broad Synonyms: duplicase
Related Synonyms: DNA duplicase activity ;   DNA nucleotidyltransferase (DNA-directed) activity ;   DNA replicase activity ;   DNA-dependent DNA polymerase activity ;   deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) activity ;   deoxyribonucleic acid duplicase activity ;   deoxyribonucleic duplicase activity ;   sequenase
Alternate IDs: GO:0003888 ;   GO:0003889 ;   GO:0003890 ;   GO:0003891 ;   GO:0003893 ;   GO:0003894 ;   GO:0003895 ;   GO:0008723 ;   GO:0015999 ;   GO:0016000
Xrefs: EC:2.7.7.7 ;   MetaCyc:DNA-DIRECTED-DNA-POLYMERASE-RXN ;   Reactome:R-HSA-9710480 "Decitabine triphosphate incorporates into DNA" ;   reactome:R-HSA-110311 "POLZ extends translesion synthesis" ;   reactome:R-HSA-110317 "Insertion of correct bases opposite the lesion by POLH" ;   reactome:R-HSA-110319 "Elongation by POLH" ;   reactome:R-HSA-110368 "POLD,POLE-mediated DNA strand displacement synthesis" ;   reactome:R-HSA-111253 "POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site" ;   reactome:R-HSA-164505 "Synthesis of full-length duplex viral DNA with a discontinuous plus strand" ;   reactome:R-HSA-164513 "3' PPT-primed initiation of plus-strand DNA synthesis"
Definition Sources: EC:2.7.7.7, GOC:vw

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