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Ontology Browser

Parent Terms Term With Siblings Child Terms
malignant peripheral nerve sheath tumor +   
neurofibroma +   
A moderately firm, benign, encapsulated tumor resulting from proliferation of SCHWANN CELLS and FIBROBLASTS that includes portions of nerve fibers. The tumors usually develop along peripheral or cranial nerves and are a central feature of NEUROFIBROMATOSIS 1, where they may occur intracranially or involve spinal roots. Pathologic features include fusiform enlargement of the involved nerve. Microscopic examination reveals a disorganized and loose cellular pattern with elongated nuclei intermixed with fibrous strands. (From Adams et al., Principles of Neurology, 6th ed, p1016)
neuroma +   
perineurioma +  
peripheral nerve sheath neoplasm +   

Exact Synonyms: Neurofibromas
Primary IDs: MESH:D009455 ;   RDO:0006211
Xrefs: GARD:7191 ;   NCI:C3272
Definition Sources: MESH:D009455

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