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Ontology Browser
Term:
severe combined immunodeficiency (DOID:627)
Annotations: Rat: (96) Mouse: (84) Human: (89) Chinchilla: (82) Bonobo: (84) Dog: (83) Squirrel: (82) Pig: (83)
Parent Terms Term With Siblings Child Terms
Amniotic Band Syndrome +  
asphyxia neonatorum +   
ataxia telangiectasia +   
B cell and dendritic cell deficiency +   
benign neonatal seizures +   
Birth Injuries +   
Bloom syndrome  
Caffey disease +   
Carnitine Palmitoyltransferase II Deficiency, Lethal Neonatal  
Cockayne syndrome +   
Colic 
combined cellular and humoral immune defects with granulomas  
Combined Immunodeficiency and Megaloblastic Anemia with or without Hyperhomocysteinemia  
Combined Immunodeficiency with Autoimmunity and Spondylometaphyseal Dysplasia  
combined T cell and B cell immunodeficiency +   
Congenital Hyperinsulinism +   
congenital nystagmus +   
congenital syphilis +  
congenital toxoplasmosis 
Cutis Laxa-Marfanoid Syndrome 
cystic fibrosis +   
Fanconi anemia +   
fetal erythroblastosis +   
hydrophthalmos +   
Hyperglycinemia, Transient Neonatal 
Hyperparathyroidism, Neonatal Severe Primary  
ichthyosis +   
immunodeficiency 12  
immunodeficiency 33  
immunodeficiency 41  
immunodeficiency 50  
immunodeficiency 54  
immunodeficiency 55  
immunodeficiency 71  
immunodeficiency 72  
immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis  
immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia  
immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia  
Infantile Hypercalcemia +   
Li-Fraumeni syndrome +   
Lung Damage, Immunodeficiency and Chromosome Breakage Syndrome  
Lynch syndrome +   
meconium aspiration syndrome  
Meconium Ileus  
Mobius syndrome +   
monocyte, dendritic cell, and NK cell deficiency +   
N syndrome 
neonatal abstinence syndrome 
Neonatal Alloimmune Thrombocytopenia  
neonatal anemia +   
neonatal diabetes +   
Neonatal Hyperbilirubinemia +   
Neonatal Hypoglycemia, Simulating Foetopathia Diabetica  
Neonatal Inflammatory Skin and Bowel Disease +   
Neonatal Pulmonary Hypertension  
Neonatal Sepsis  
Nijmegen breakage syndrome +   
Nijmegen Breakage Syndrome-Like Disorder  
ophthalmia neonatorum 
persistent fetal circulation syndrome  
Posttransfusion Purpura  
Premature Infant Diseases +   
Rothmund-Thomson syndrome +   
Sclerema Neonatorum 
severe combined immunodeficiency +   
A combined T cell and B cell immunodeficiency that is caused by a defect in infection-fighting immune cells resulting in individuals with non-functional immune systems. (DO)
T cell, B cell, and NK cell deficiency +   
thanatophoric dysplasia +   
transient neonatal thrombocytopenia 
umbilical hernia +   
vitamin K deficiency bleeding  
Werner syndrome +   
Wolman disease +   
xeroderma pigmentosum +   
 adenosine deaminase deficiency  
 CD3delta deficiency 
 CD3epsilon deficiency 
 CD3gamma deficiency 
 CD3zeta deficiency 
 CD45 deficiency 
 coronin-1A deficiency  
 HLA Class 1 Deficiency 
 immunodeficiency 10  
 immunodeficiency 11A  
 immunodeficiency 15B  
 immunodeficiency 19  
 immunodeficiency 22  
 immunodeficiency 24  
 immunodeficiency 26  
 immunodeficiency 48  
 immunodeficiency 9  
 Immunoskeletal Dysplasia with Neurodevelopmental Abnormalities  
 interleukin-7 receptor alpha deficiency 
 janus kinase-3 deficiency  
 MHC class I deficiency  
 MHC class II deficiency  
 Omenn syndrome  
 recombinase activating gene 1 deficiency 
 recombinase activating gene 2 deficiency  
 reticular dysgenesis  
 Reticuloendotheliosis, X-Linked 
 Severe Combined Immunodeficiency with Microcephaly, Growth Retardation, and Sensitivity to Ionizing Radiation  
 severe combined immunodeficiency with sensitivity to ionizing radiation  
 Severe Combined Immunodeficiency, Atypical 
 severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positive  
 Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Positive, NK Cell-Negative  
 severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, NK cell-positive  
 Short-Limb Skeletal Dysplasia with Severe Combined Immunodeficiency 
 T-cell immunodeficiency, congenital alopecia, and nail dystrophy  
 T-Cell Immunodeficiency, Recurrent Infections, and Autoimmunity with or without Cardiac Malformations  
 X-linked severe combined immunodeficiency  

Synonyms
Exact Synonyms: Bare Lymphocyte Syndrome ;   Familial Reticuloendothelioses ;   Familial Reticuloendotheliosis ;   SCID ;   Severe Combined Immune Deficiency ;   Severe Combined Immunodeficiencies ;   Severe Combined Immunodeficiency Syndrome ;   bare lymphocyte syndromes ;   combined T and B cell inborn immunodeficiency ;   severe combined immunodeficiency disease ;   severe combined immunologic deficiency
Narrow Synonyms: Severe combined immunodeficiency disease, autosomal
Primary IDs: MESH:D016511
Alternate IDs: OMIA:000220
Xrefs: GARD:7628 ;   NCI:C3472
Definition Sources: http://www.merriam-webster.com/medlineplus/severe%20combined%20immunodeficiency "DO", http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gnd&part=severecombinedimmunodeficiency "DO", http://www.scid.net/ "DO"

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