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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
Ovarian Dysgenesis +   
premature ovarian failure +   
Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections.

Synonyms
Exact Synonyms: Gonadotropin Resistant Ovary Syndrome ;   POF ;   POFX ;   Premature Ovarian Failure, X Linked ;   X linked hypergonadotropic ovarian failure ;   fragile X associated primary ovarian insufficiency ;   fragile X premature ovarian failure ;   premature ovarian insufficiency ;   primary ovarian insufficiency ;   resistant ovary syndrome
Primary IDs: MESH:D016649
Alternate IDs: RDO:0000256
Xrefs: ICD10CM:E28.3 ;   NCI:C113352 ;   OMIM:PS311360 ;   ORDO:619
Definition Sources: http://en.wikipedia.org/wiki/Premature_ovarian_failure "DO", http://www.merckmanuals.com/professional/gynecology_and_obstetrics/menstrual_abnormalities/premature_ovarian_insufficiency_or_failure.html "DO", MESH:D016649

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.