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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
scleroderma +     
localized scleroderma +   
systemic scleroderma +   
A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.

Synonyms
Exact Synonyms: progressive scleroderma ;   progressive systemic sclerosis ;   scleroderma syndrome ;   systemic sclerosis
Primary IDs: MESH:D012595
Xrefs: GARD:9748 ;   ICD10CM:M34.0 ;   ICD10CM:M34.9 ;   ICD9CM:710.1 ;   NCI:C72070
Definition Sources: https://ghr.nlm.nih.gov/condition/systemic-scleroderma "DO", MESH:D012595

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.