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Ontology Browser
Term:
Parent Terms Term With Siblings Child Terms
motor peripheral neuropathy +     
paraplegia +     
Alstrom syndrome  
Brown-Sequard syndrome 
Cardioneuromyopathy with Hyaline Masses and Nemaline Rods 
Charcot-Marie-Tooth disease +   
Congenital Anterior Cervical Hypertrichosis with Peripheral Sensory and Motor Neuropathy 
distal hereditary motor neuronopathy type 7 +   
essential tremor 2  
Fryns Macrocephaly 
Giant Axonal Neuropathy +   
Hagemoser Weinstein Bresnick Syndrome 
Hereditary Motor and Sensory Neuropathy with Excessive Myelin Folding Complex, Autosomal Recessive 
Hereditary Motor and Sensory Neuropathy, Okinawa Type  
hereditary neuropathy with liability to pressure palsies  
Hereditary Sensorimotor Neuropathy with Upper Motor Neuron, Visual Pathway and Autonomic Disturbance 
Hereditary Sensory Neuropathy with Spastic Paraplegia, Autosomal Recessive  
hereditary spastic paraplegia +   
A group of inherited diseases that share similar phenotypes but are genetically diverse. Different genetic loci for autosomal recessive, autosomal dominant, and x-linked forms of hereditary spastic paraplegia have been identified. Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity. Peripheral sensory neurons may be affected in the later stages of the disease. (J Neurol Neurosurg Psychiatry 1998 Jan;64(1):61-6; Curr Opin Neurol 1997 Aug;10(4):313-8)
Hypomyelination with Brainstem and Spinal Cord Involvement and Leg Spasticity  
Mental Retardation with Spastic Paraplegia 
Neuropathy, Hereditary Thermosensitive 
Optic Atrophy Spastic Paraplegia Syndrome 
Polyneuropathy, Lethal Neonatal, Axonal Sensorimotor, Autosomal Recessive 
Refsum disease +   
sensory ataxic neuropathy, dysarthria, and ophthalmoparesis  
Slowed Nerve Conduction Velocity, Autosomal Dominant  
Spastic Paraplegia, Ataxia, and Mental Retardation 
SPOAN syndrome  
Tamari Goodman Syndrome 
 3-methylglutaconic aciduria type 3  
 Amyotrophic Dystonic Paraplegia 
 Arena Syndrome 
 Bahemuka Brown syndrome 
 Fitzsimmons Walson Mellor Syndrome 
 Fitzsimmons-Guilbert Syndrome  
 Fitzsimmons-McLachlan-Gilbert syndrome 
 Hereditary Spastic Paralysis, Infantile Onset Ascending  
 hereditary spastic paraplegia 10  
 hereditary spastic paraplegia 11  
 hereditary spastic paraplegia 12  
 hereditary spastic paraplegia 13  
 hereditary spastic paraplegia 14 
 hereditary spastic paraplegia 15  
 hereditary spastic paraplegia 16 
 hereditary spastic paraplegia 17  
 hereditary spastic paraplegia 18  
 hereditary spastic paraplegia 19 
 hereditary spastic paraplegia 2  
 hereditary spastic paraplegia 23  
 hereditary spastic paraplegia 24 
 hereditary spastic paraplegia 25 
 hereditary spastic paraplegia 26  
 hereditary spastic paraplegia 27 
 hereditary spastic paraplegia 28  
 hereditary spastic paraplegia 29 
 hereditary spastic paraplegia 30  
 hereditary spastic paraplegia 31  
 hereditary spastic paraplegia 32 
 hereditary spastic paraplegia 33  
 hereditary spastic paraplegia 34 
 hereditary spastic paraplegia 35  
 hereditary spastic paraplegia 36 
 hereditary spastic paraplegia 37 
 hereditary spastic paraplegia 38 
 hereditary spastic paraplegia 39  
 hereditary spastic paraplegia 3A  
 hereditary spastic paraplegia 4  
 hereditary spastic paraplegia 41 
 hereditary spastic paraplegia 42  
 hereditary spastic paraplegia 43  
 hereditary spastic paraplegia 44  
 hereditary spastic paraplegia 45  
 hereditary spastic paraplegia 46  
 hereditary spastic paraplegia 47  
 hereditary spastic paraplegia 48  
 hereditary spastic paraplegia 49  
 hereditary spastic paraplegia 50  
 hereditary spastic paraplegia 51  
 hereditary spastic paraplegia 52  
 hereditary spastic paraplegia 53  
 hereditary spastic paraplegia 54  
 hereditary spastic paraplegia 55  
 hereditary spastic paraplegia 56  
 hereditary spastic paraplegia 57  
 hereditary spastic paraplegia 5A  
 hereditary spastic paraplegia 6  
 hereditary spastic paraplegia 61  
 hereditary spastic paraplegia 62  
 hereditary spastic paraplegia 63  
 hereditary spastic paraplegia 64  
 hereditary spastic paraplegia 7  
 hereditary spastic paraplegia 72  
 hereditary spastic paraplegia 73  
 hereditary spastic paraplegia 74  
 hereditary spastic paraplegia 75  
 hereditary spastic paraplegia 76  
 hereditary spastic paraplegia 77  
 hereditary spastic paraplegia 8  
 hereditary spastic paraplegia 9A  
 hereditary spastic paraplegia 9B  
 Limb Defects, Distal Transverse, with Mental Retardation and Spasticity 
 MASA syndrome  
 MAST syndrome  
 Mental Retardation Spasticity Ectrodactyly 
 Nakamura Osame syndrome 
 Roy Maroteaux Kremp Syndrome 
 spastic ataxia 1  
 spastic ataxia 2  
 spastic ataxia 3  
 Spastic Diplegia Infantile Type 
 Spastic Paraplegia 78, Autosomal Recessive  
 Spastic Paraplegia 79, Autosomal Recessive  
 Spastic Paraplegia 80, Autosomal Dominant  
 Spastic Paraplegia and Evans Syndrome 
 Spastic Paraplegia Epilepsy Mental Retardation 
 Spastic Paraplegia Neuropathy Poikiloderma 
 Spastic Paraplegia Type 5B, Recessive 
 Spastic Paraplegia with Associated Extrapyramidal Signs 
 Spastic Paraplegia with Kallmann Syndrome 
 Spastic Paraplegia with Myoclonic Epilepsy 
 Spastic Paraplegia with Precocious Puberty 
 SPASTIC PARAPLEGIA, INTELLECTUAL DISABILITY, NYSTAGMUS, AND OBESITY  
 Spastic Paraplegia, Optic Atrophy, and Dementia 
 Spastic Paraplegia, Optic Atrophy, Microcephaly, and XY Sex Reversal 
 Spastic Paraplegia, Sensorineural Deafness, Mental Retardation, and Progressive Nephropathy 
 SPASTIC TETRAPLEGIA AND AXIAL HYPOTONIA, PROGRESSIVE  
 SPASTIC TETRAPLEGIA, THIN CORPUS CALLOSUM, AND PROGRESSIVE MICROCEPHALY  
 Troyer syndrome  
 Volcke Soekarman Syndrome 

Synonyms
Exact Synonyms: CMT with Pyramidal Features ;   Charcot Marie Tooth Disease with Pyramidal Features, Autosomal Dominant ;   French settlement disease ;   HMSN 5 ;   HMSN Type V ;   HMSN V ;   HMSN V (Hereditary Motor and Sensory Neuropathy Type V) ;   Hereditary Motor And Sensory Neuropathy V ;   Hereditary Motor Sensory Neuropathy with Pyramidal Signs ;   Hereditary Motor and Sensory Neuropathy 5 ;   Hereditary Spastic Paraplegias ;   Hereditary X Linked Recessive Spastic Paraplegia ;   Hypertrophic Motor Sensory Neuropathy Spastic Paraplegia ;   Peroneal Muscular Atrophy with Pyramidal Features, Autosomal Dominant ;   Strumpell-Lorrain disease ;   familial spastic paraplegia ;   hereditary spastic paraparesis ;   type V hereditary motor and sensory neuropathy
Narrow Synonyms: Autosomal Dominant Hereditary Spastic Paraplegia ;   Autosomal Recessive Hereditary Spastic Paraplegia ;   Dominant Spastic Paraplegia ;   PURE OR COMPLEX AUTOSOMAL RECESSIVE SPASTIC PARAPLEGIA ;   Recessive Spastic Paraplegia ;   X-linked hereditary spastic paraplegia
Primary IDs: MESH:D015419
Alternate IDs: RDO:0000354
Xrefs: GARD:6637 ;   OMIM:PS303350
Definition Sources: MESH:D015419, http://en.wikipedia.org/wiki/Familial_spastic_paraplegia

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