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Ontology Browser

Term:
focal segmental glomerulosclerosis (DOID:1312)
Annotations: Rat: (113) Mouse: (86) Human: (89) Chinchilla: (77) Bonobo: (78) Dog: (78) Squirrel: (80) Pig: (81)
Parent Terms Term With Siblings Child Terms
glomerulosclerosis +     
focal segmental glomerulosclerosis +   
A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE.

Synonyms
Exact Synonyms: FGS ;   FSGS ;   Focal Glomerulosclerosis ;   Focal Sclerosing Glomerulonephritides ;   Focal Sclerosing Glomerulonephritis ;   Segmental Glomerular Hyalinosis ;   Segmental Hyalinosis ;   focal glomerular sclerosis
Narrow Synonyms: FOCAL SEGMENTAL GLOMERULOSCLEROSIS AND DILATED CARDIOMYOPATHY
Primary IDs: MESH:D005923
Xrefs: GARD:6517 ;   NCI:C37308 ;   OMIM:PS603278
Definition Sources: MESH:D005923

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