Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

Ontology Browser

thrombotic thrombocytopenic purpura (DOID:10772)
Annotations: Rat: (8) Mouse: (8) Human: (8) Chinchilla: (7) Bonobo: (7) Dog: (8) Squirrel: (7) Pig: (7)
Parent Terms Term With Siblings Child Terms
thrombophilia +     
Acquired Amegakaryocytic Thrombocytopenia 
Activated Protein C Resistance  
Antithrombin Deficiency Type 2 
antithrombin III deficiency  
autoimmune thrombocytopenic purpura  
disseminated intravascular coagulation +   
Drug-Induced Immune Thrombocytopenia +   
Factor V Excess with Spontaneous Thrombosis 
Hereditary Thrombophilia  
Posttransfusion Purpura  
protein C deficiency +   
protein S deficiency +   
Thrombomodulin Anomalies, Familial 
Thrombophilia Due To Elevated Histidine-Rich Glycoprotein  
Thrombophilia due to Thrombomodulin Defect  
Thrombophilia, Familial, due to Decreased Release of Tissue Plasminogen Activator  
thrombotic thrombocytopenic purpura +   
An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical features include THROMBOCYTOPENIA; HEMOLYTIC ANEMIA; AZOTEMIA; FEVER; and thrombotic microangiopathy. The classical form also includes neurological symptoms and end-organ damage, such as RENAL FAILURE.
X-Linked Thrombophilia, due to Factor IX Defect  

Exact Synonyms: Congenital Thrombotic Thrombocytopenic Purpura ;   Familial Thrombotic Microangiopathy ;   Familial Thrombotic Thrombocytopenia Purpura ;   Familial Thrombotic Thrombocytopenic Purpura ;   MICROANGIOPATHIC HEMOLYTIC ANEMIA ;   Microangiopathic Hemolytic Anemia, Congenital ;   Moschcowitz Disease ;   Moschcowitz's syndrome ;   Moschkowitz Disease ;   TTP ;   Thrombotic Thrombopenic Purpura ;   USS ;   deficiency of Upshaw factor
Narrow Synonyms: Adult Onset Purpura, Thrombotic Thrombocytopenic ;   Familial TTP/HUS ;   Familial thrombotic thrombocytopenic purpura / haemolytic uraemic syndrome ;   Upshaw-Schulman syndrome ;   chronic relapsing thrombotic thrombocytopenic purpura
Primary IDs: MESH:D011697 ;   RDO:0002621
Alternate IDs: OMIM:274150
Xrefs: GARD:9430 ;   ICD10CM:M31.1 ;   NCI:C78797
Definition Sources: MESH:D011697

paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.