GSK2181236A response/sensitivity measurement - Ontology Browser

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GSK2181236A response/sensitivity measurement (CMO:0003414)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0) Naked Mole-rat: (0) Green Monkey: (0)

Parent Terms

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Child Terms

chemical response/sensitivity measurement + is-a

A23187 response/sensitivity measurement +

acetylcholine response/sensitivity measurement +

angiotensin II response/sensitivity measurement +

BAY60-4552 response/sensitivity measurement +

carbachol response/sensitivity measurement +

GSK2181236A response/sensitivity measurement +

Measurement of an organism's, organ's, tissue's or cell's capacity to respond, such as by a change in activity, state or condition, to GSK2181236A, a chemical that belongs to a novel group of small molecule compounds which increase the enzymatic activity of soluble guanylate cyclase.

methacholine response/sensitivity measurement +

norepinephrine response/sensitivity measurement +

phenylephrine response/sensitivity measurement +

potassium chloride response/sensitivity measurement +

sodium nitroprusside response/sensitivity measurement +

concentration of GSK2181236A at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)

GSK2181236A-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel

Synonyms
Exact Synonyms:	1-(6-{2-[({3-methyl-4 -[(trifluoromethyl)oxy]-4-biphenylyl}methyl)oxy] phenyl}-2-pyridinyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid response/sensitivity measurement
Xrefs:	PMID:22783192
Definition Sources:	PMID:22783192

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