Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
(+)-conocarpan  
(+)-epicatechin +   
(-)-beta-caryophyllene 
(-)-cubebin 
(-)-larreatricin 
(2S)-2-(4-\{[(1R,2S)-2-hydroxycyclopentyl]methyl\}phenyl)propanoic acid 
(2S,3S)-2,3-dihydro-3-hydroxymethyl-2-(4-hydroxyphenyl)-5-(E)-propenylbenzofuran 
(E)-2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside 
(E)-3-tosylacrylonitrile 
(R)-ketamine 
(R)-ketorolac +   
(RS)-mallotophilippen E 
(S)-etodolac 
(S)-ketorolac +   
A 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has S configuration. While (S)-ketorolac is a COX1 and COX2 inhibitor, both enantiomers exhibit analgesic effects. Racemic ketorolac, known simply as ketorolac, is used (mainly as the tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis.
1-(4'-hydroxy-3'-methoxyphenyl)-7-phenyl-3-heptanone 
1-(all-cis-docosa-7,10,13,16-tetraenoyl)glycerol 
13,14,15,16-tetranorlabdane-8alpha,12,18-triol 
2-(2,4-dihydroxyphenyl)-5-(E)-propenylbenzofuran 
2-(2-hydroxy-4-methoxyphenyl)-5-(3-hydroxypropyl)benzofuran 
2-(4-hydroxyphenyl)-5-(E)-propenylbenzofuran 
4-(methylamino)antipyrine 
4-aminoantipyrine 
5-(3-hydroxypropyl)-2-(2-methoxy-4-hydroxyphenyl)benzofuran 
5-methoxy-8-(2'-hydroxy-3'-buthoxy-3'-methylbutyloxy)psoralen 
6-diazo-5-oxo-L-norleucine 
8alpha,19-dihydroxylabd-13E-ene-15-oic acid 
[5-fluoro-1-(4-isopropylbenzylidene)-2-methylinden-3-yl]acetic acid 
aceclofenac  
acemetacin  
acetosyringone +  
acetylsalicylic acid +   
adapalene  
adenosine +   
alclofenac  
alminoprofen 
almotriptan +   
almotriptan malate 
amantadine  
amfenac +   
amfenac sodium hydrate 
aminophenazone  
amlexanox  
amodiaquine +   
ampiroxicam 
antipyrine +   
apazone  
apigenin 7-O-beta-D-glucoside  
apigenin 7-O-beta-D-glucoside(1-) 
apocynin  
apremilast 
arasertaconazole +   
aspirin-triggered resolvin D1 
baicalin  
balsalazide +   
balsalazide disodium 
balsaminolate 
bauhinoxepin F 
bauhinoxepin I 
bendazac 
benoxaprofen  
benzoylmesaconine  
benzydamine  
betulin +   
biphenyl-4-ylacetic acid +  
bromfenac  
bromfenac sodium salt +  
bromfenac sodium salt sesquihydrate 
bufexamac 
bumadizone 
bumadizone calcium +  
bumadizone calcium hemihydrate 
bunodosine 391 
butalbital 
carbamazepine +   
carprofen +   
cassiatannin A 
celecoxib  
centaureidin 
cimetidine +   
cimicoxib 
cinnamtannin B-1 
cinnamtannin D-1 
cis-trans-nepetalactone 
clofazimine  
clonixin 
clonixin lysine salt 
corilagin  
crisaborole 
decursinol 
dehydrocostus lactone  
deracoxib 
dexibuprofen 
dexketoprofen 
dexmedetomidine +   
diclofenac +   
difenpiramide 
diflunisal  
dinitrogen oxide  
dithiosalicylic acid 
droxicam 
ecgonine methyl ester +   
eletriptan  
eletriptan hydrobromide 
enprofylline +  
esketamine +  
esketamine hydrochloride 
etodolac +   
etoricoxib  
fenbufen  
fendosal 
fenoprofen  
fenoprofen calcium 
fenoprofen calcium (anhydrous) +  
firocoxib 
flufenamate 
flufenamic acid  
flunixin  
flunixin meglumine  
flunoxaprofen 
fluoxetine  
fluoxetine hydrochloride 
flurbiprofen +   
fomitopinic acid A 
fomitoside E 
fomitoside F 
gallic acid +   
garenoxacin 
ginkgetin  
glafenine  
humulone 
ibufenac  
ibuprofen +   
ibuproxam 
impatienol 
impatienolate 
indometacin +   
indoprofen  
ipomotaoside A 
isoxicam 
kebuzone 
ketamine +   
ketamine hydrochloride +  
ketoprofen  
ketorolac  
ketorolac tromethamine 
leflunomide  
LM-1685  
lonazolac 
lonazolac calcium 
lornoxicam  
loxoprofen +   
loxoprofen sodium +  
loxoprofen sodium hydrate 
lumiracoxib  
lupulin A 
magnesium sulfate +   
mallotophilippen C 
mallotophilippen D 
matsudone A 
mavacoxib 
meclofenamic acid  
mefenamic acid  
meloxicam  
mesalamine  
meso-3,3'-didemethoxynectandrin B 
metamizole 
metamizole sodium  
metiazinic acid 
miroprofen 
mitoxantrone +   
mofebutazone 
multifidol glucoside 
myricetin +   
N-phenylacetamide +   
nabumetone  
naproxcinod 
naproxen +   
naproxen sodium 
naproxol 
nedocromil  
nefazodone +   
nepafenac 
nimesulide  
nitroflurbiprofen  
nitrosulindac 
non-narcotic analgesic +   
nortriptyline  
NS-398  
O-methylsalicylic acid +   
O-propanoylcarnitine +  
oleocanthal 
olsalazine 
olsalazine sodium 
opioid analgesic +   
oxametacin 
oxaprozin  
oxyphenbutazone +   
oxyphenbutazone hydrate 
paracetamol +   
parameritannin A-1 
parecoxib  
parthenolide +   
patuletin 
phenylbutazone +   
pirfenidone  
piroxicam +   
proglumetacin +  
proglumetacin dimaleate 
propoxyphene 
propyphenazone 
quercetin 4'-O-alpha-L-rhamnopyranosyl-3-O-beta-D-allopyranoside 
rataniaphenol I 
rataniaphenol II 
rataniaphenol III 
robenacoxib 
rofecoxib  
rosmarinic acid +   
salicin +   
salsalate  
SC-58125  
SC560 
sertaconazole  
sertaconazole nitrate 
sodium (2-amino-3-benzoylphenyl)acetate +  
sodium gallate 
sodium meclofenamate monohydrate 
sophoraisoflavanone A 
sulfasalazine  
sulindac +   
sulindac sulfide  
sulindac sulfone  
suprofen  
suxibuzone  
tenidap  
tenoxicam  
tepoxalin  
teriflunomide  
tiaprofenic acid  
tilmacoxib 
tolfenamic acid  
tolmetin  
tolmetin sodium +  
tolmetin sodium dihydrate 
U50488  
valdecoxib +   
valerylsalicylic acid 
vedaprofen 
venlafaxine +   
willow bark extract 
WIN 55212-2  
wogonin +   
ximoprofen 
zileuton  
zomepirac  
 ketorolac  

Synonyms
Exact Synonyms: (1S)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
Related Synonyms: (-)-ketorolac ;   Formula=C15H13NO3 ;   InChI=1S/C15H13NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13/h1-7,11H,8-9H2,(H,18,19)/t11-/m0/s1 ;   InChIKey=OZWKMVRBQXNZKK-NSHDSACASA-N ;   SMILES=OC(=O)[C@H]1CCn2c1ccc2C(=O)c1ccccc1
Xrefs: CAS:66635-92-5 "ChemIDplus" ;   PMID:10027870 "Europe PMC" ;   PMID:10223774 "Europe PMC" ;   PMID:10593468 "Europe PMC" ;   PMID:15584071 "Europe PMC" ;   PMID:17456651 "Europe PMC" ;   PMID:19281996 "Europe PMC" ;   PMID:23447046 "Europe PMC" ;   PMID:9549656 "Europe PMC" ;   Reaxys:6064296 "Reaxys"
Cyclic Relationships: is_enantiomer_of CHEBI:76227

paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.