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Term:
Parent Terms Term With Siblings Child Terms
(+)-TACP 
(1S,2S,5S)-2-(4-glutaridylbenzyl)-5-phenylcyclohexan-1-ol 
(aminooxy)acetic acid  
(R)-efonidipine +  
(R)-nicardipine +   
(R)-oxybutynin +   
(S)-4-amino-5-oxopentanoic acid 
(S)-efonidipine +  
(S)-nicardipine +   
1-[(3-carboxypropyl)amino]-1-deoxy-beta-D-fructofuranose 
11-hydroxy-N-desmethyl 12-keto pretubulysin D 
12-HETE-GABA 
15-HETE-GABA 
2,3,4-triacetamido-2,3,4-trideoxy-L-arabinose 
2,4-diaminobutyric acid +   
2,6-diamino-7-hydroxy-azelaic acid 
2-Aminobenzylstatine 
2-aminoethoxydiphenylborane  
2-hydroxyputrescine 
3,3-diethyl-2-pyrrolidinone 
3-amino-N-(3-amino-3-iminopropyl)cyclopentane-1-carboxamide 
3-aminoadipic acid +  
3-aminopropanesulfonic acid 
4-(1-oxoeicosa-5,8,11,14-tetraenylamino)butanoic acid 
4-(4-methylanilino)-N'-[(6-oxo-5-prop-2-enyl-1-cyclohexa-2,4-dienylidene)methyl]butanehydrazide 
4-(benzoylamino)-3-hydroxybutanoic acid 
4-(methylamino)butyric acid 
4-[(E)-\{amino[(3-methylbut-2-en-1-yl)amino]methylidene\}amino]butanoic acid 
4-[[4-(dimethylamino)-7,7-dimethyl-6,8-dihydropyrimido[4,5-b][1,4]benzothiazin-9-yl]amino]butanoic acid 
4-Amino-2-methylenebutanoic acid 
4-amino-3-methylbutanoic acid 
4-amino-pentanoic acid 
4-aminobutanoyl-CoA 
4-chloro-N-[4-[3-(methylthio)anilino]-4-oxobutyl]benzamide 
4R-aminopentanoic acid 
4S-aminopentanoic acid 
5,7-dihydroxy-4'-methoxyflavone +   
5-amino-5-deoxy-3-dehydroshikimic acid 
5-aminocyclohexa-1,3-diene-1-carboxylic acid +  
5-chlorospiro[indole-3,2'-[1,3]oxathiolan]-2(1H)-one 
5-Deoxy-5-aminoshikimic acid 
5alpha-dihydrodeoxycorticosterone 
6-[5-(1-carboxy-4-N-carboxylate)-3-methylpent-2-enyl]-7-hydroxy-5-methoxy-4-methylphthalan-1-one 
6-methoxy-2-benzoxazolinone 
acetazolamide +   
adinazolam  
alpha-asarone 
alprazolam  
AminoDHQ 
aminoglutethimide +   
amlodipine +   
amlodipine benzenesulfonate +  
androsterone +   
apinocaltamide 
Arbaclofen 
Atagabalin 
Bacillcoumacin B 
baclofen  
Benzoic acid, 3-[[(3-carboxycyclohexyl)amino]carbonyl]-4-[3-[4-(4-phenoxybutoxy)phenyl]propoxy]- 
Benzoic acid, 3-[[(3-carboxycyclohexyl)amino]carbonyl]-4-[3-[4-[4-(cyclohexyloxy)butoxy]phenyl]propoxy]- 
bepridil +   
bevantolol +   
bevantolol hydrochloride +  
brivaracetam 
carbamazepine +   
Carboxyprimaquine 
carnosine +   
CGP 78608 
CGP 78608 hydrochloride 
cilnidipine  
cinnarizine  
cinolazepam 
clobazam  
clonazepam  
clorazepic acid 
cobalt dichloride +   
cromoglycic acid 
devapamil 
diazepam +   
didesethylflurazepam 
diethylstilbestrol +   
diltiazem  
diltiazem hydrochloride 
diltiazem(1+) +  
dipotassium clorazepate 
Distichonic acid A 
Distichonic acid B 
dizocilpine  
dizocilpine maleate  
dotarizine 
efonidipine 
Elagolix 
eliprodil  
Epsilon-(Carboxyethyl)lysine 
eslicarbazepine acetate 
esoxybutynin +   
estazolam  
ethosuximide +   
ethotoin +   
ethyl-4-aminobutyrate 
eupatorin  
ezogabine  
fasudil  
fasudil hydrochloride +  
fasudil hydrochloride hydrate 
felbamate  
felodipine  
flurazepam +   
Fuscoatramide 
gabapentin +   
gabapentin enacarbil 
Gaburedin D 
gamma-amino-beta-hydroxybutyric acid +  
gamma-amino-gamma-cyanobutanoic acid +  
gamma-aminobutyric acid +   
gamma-decalactone  
glutaurine 
glutaurine zwitterion 
glutaurine(1-) 
GSK-5498A 
Guamamide 
hentriacontan-16-one 
hispidulin  
Hoiamide C 
homocarnosine +  
hopantenic acid 
Isomugineic acid 
Isoputreanine 
keto-D-fructose 1,6-bisphosphate  
L-cycloserine +  
L-lysine +   
Laccarin A 
Lagriamide 
lamotrigine  
lanperisone 
lanperisone hydrochloride 
levetiracetam  
licarbazepine +  
magnesium sulfate +   
Malyngamide 3 
meclofenamic acid  
melatonin +   
mephenytoin  
mephobarbital  
methyl 4-(3,4-dihydroxybenzamido)butanoate 
Methyl 4-(diaminomethylideneamino)butanoate 
methyl 4-aminobutanoate 
midafotel 
midazolam +   
midazolam hydrochloride 
Mildiomycin 
mono-isopropyl-disopyramide  
Mycosporine glutamicol 
Mycosporine hydroxyglutamicol 
Mycosporine-GABA 
N-Acetylisoputreanine 
N-acyl-gamma-aminobutyric acid +  
N-Arachidonoyl-3-hydroxy-g-Aminobutyric Acid 
N-arachidonoyl-3-hydroxy-gamma-aminobutyric acid 
N-arachidonoylserotonin 
N-carboxyethyl-gamma-aminobutyric acid 
N-Linoleoyl-4-Aminobutyric Acid 
N-Oleoyl GABA 
N-Palmitoyl GABA 
N-Stearoyl GABA 
naxagolide 
naxagolide hydrochloride 
nemadipine-A 
nicardipine  
nickel dichloride +   
nifedipine  
nimetazepam  
nimodipine  
nisoldipine  
Nitracidomycin A 
Nitracidomycin B 
nitrazepam +   
nitrendipine  
nordazepam  
norverapamil  
ochratoxin A +   
ochratoxin B  
omega-conotoxin GVIA  
omeprazole +   
otophylloside B 
oxcarbazepine  
oxybutynin +   
palmitoyl ethanolamide  
paramethadione 
paxilline  
Peniamidone D 
perampanel +   
perampanel hydrate 
Pestalotiopamide B 
Pestalotiopamide C 
phenibut 
phenobarbital +   
phenytoin  
piCRAC-1 +  
pivagabine 
pregabalin  
A gamma-amino acid that is gamma-aminobutyric acid (GABA) carrying an isobutyl substitutent at the beta-position (the S-enantiomer). Binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues.
prilocaine +   
primidone  
propofol +   
Pseudotrienic acid A 
Pseudotrienic acid B 
pyrrolidine dithiocarbamate  
Ro 25-6981  
Ro 25-6981 maleate 
Ru360 
santacruzamate A 
SKF-96365 hydrochloride  
sodium meclofenamate monohydrate 
sodium selenate  
sodium valproate +   
solasodine +   
solasodine(1+) 
T-type calcium channel blocker +   
thalidomide +   
thapsigargin  
thiopental  
tiagabine  
tiagabine hydrochloride 
tilmicosin  
topiramate  
tranilast  
trans-3-Aminocyclopentane-1-carboxylic acid 
trimethadione 
trioctanoin 
troglitazone  
U50488  
Usenamine D 
Usenamine E 
Usenamine F 
valproate semisodium 
valproic acid +   
vanillin +   
verapamil  
vigabatrin  
Xenocoumacin 1 
zaleplon  
Zeamine I 
zofenopril 
zofenopril calcium 
zofenoprilat 
zofenoprilat arginine 
zonisamide  
zuranolone 

Synonyms
Exact Synonyms: (3S)-3-(aminomethyl)-5-methylhexanoic acid
Related Synonyms: (S)-3-Isobutyl GABA ;   3-Isobutyl GABA ;   Formula=C8H17NO2 ;   InChI=1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)/t7-/m0/s1 ;   InChIKey=AYXYPKUFHZROOJ-ZETCQYMHSA-N ;   Lyrica ;   SMILES=CC(C)C[C@H](CN)CC(O)=O
Alternate IDs: MESH:D000069583
Xrefs: CAS:148553-50-8 ;   DrugBank:DB00230 ;   Drug_Central:2255 ;   KEGG:D02716
Xref Mesh: MESH:D000069583
Xrefs: PMID:22339078 ;   PMID:22345870 ;   PMID:22362672 ;   PMID:22366121 ;   PMID:22404404 ;   PMID:22413436 ;   PMID:22415534 ;   PMID:22415535 ;   PMID:22424859 ;   PMID:22431439 ;   PMID:22448469 ;   PMID:22449111 ;   PMID:22459341 ;   PMID:22468635 ;   PMID:22470326 ;   PMID:22473300 ;   PMID:22473872 ;   PMID:22476240 ;   PMID:22480279 ;   Patent:EP1178034 ;   Patent:EP2418194 ;   Patent:US2008311635 ;   Patent:US6359169 ;   Reaxys:8404778 ;   Wikipedia:Pregabalin

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