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Term:
4-fluoro-N-\{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl\}benzamide hydrochloride (CHEBI:64099)
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Parent Terms Term With Siblings Child Terms
(1R,2S)-tranylcypromine hydrochloride +  
(1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride  
(1S,2R)-5-methoxy-1-methyl-2-(propylamino)tetralin hydrochloride 
(1S,2R)-tranylcypromine hydrochloride +  
(2R,3S)-EHNA hydrochloride 
(3S)-3-\{[3',4'-difluoro-5-(\{4'-fluoro-6-[(3S)-pyrrolidinium-3-yloxy][biphenyl]-3-yl\}carbamoyl)[biphenyl]-2-yl]oxy\}pyrrolidinium dichloride 
(aminooxy)acetic acid hemihydrochloride 
(R)-adrenaline hydrochloride 
(R)-cyclopentolate hydrochloride 
(R)-cycrimine hydrochloride 
(R)-donepezil hydrochloride +   
(R)-DRF053 hydrochloride hydrate 
(R)-fluoxetine hydrochloride +   
(R)-nefopam hydrochloride +  
(R)-prasugrel hydrochloride +   
(R)-tetrindole hydrochloride +  
(R,R)-tramadol hydrochloride +  
(R,S,S,S)-nebivolol hydrochloride +  
(S)-2-methyl-1-(4-methylisoquinoline-5-sulfonyl)-1,4-diazepane dihydrochloride 
(S)-cyclopentolate hydrochloride 
(S)-cycrimine hydrochloride 
(S)-donepezil hydrochloride +   
(S)-fenfluramine +   
(S)-fenfluramine hydrochloride 
(S)-fluoxetine hydrochloride +   
(S)-nefopam hydrochloride +  
(S)-nicotine +   
(S)-prasugrel hydrochloride +   
(S)-ropivacaine hydrochloride (anhydrous) +  
(S)-tetrindole hydrochloride +  
(S)-verapamil hydrochloride +  
(S,R,R,R)-nebivolol hydrochloride +  
(S,S)-tramadol hydrochloride +  
1,2-dimethylhydrazine dihydrochloride 
1-(3-(trifluoromethyl)phenyl)piperazine +   
1-(3-chlorophenyl)piperazine  
1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride 
1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine hydrochloride 
1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride 
1-benzyl-2-chloromethylimidazole hydrochloride 
1-benzylpiperazine  
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide hydrochloride +  
2-(chloromethyl)-4,5-dihydro-1H-imidazole hydrochloride 
2-(chloromethyl)pyridine hydrochloride 
2-dimethylaminoethyl chloride hydrochloride 
2-methyl-6-(phenylethynyl)pyridine  
2-methyl-6-(phenylethynyl)pyridine hydrochloride 
2-methylserotonin  
3,6-diamino-10-methylacridinium chloride.HCl +  
3,6-diaminoacridine dihydrochloride +  
3,6-diaminoacridine monohydrochloride +  
3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol hydrochloride 
3beta-(2-diethylaminoethoxy)androst-5-en-17-one hydrochloride  
4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline +   
4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline dimaleate  
4-\{2-[(2-hydroxybenzyl)amino]ethyl\}-2,5-dimethoxybenzonitrile.HCl 
4-fluoro-N-\{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl\}benzamide 
4-fluoro-N-\{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl\}benzamide hydrochloride  
A hydrochloride salt that is obtained by reaction of 4-fluoro-N-{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl}benzamide with one equivalent of hydrogen chloride. Highly potent selective 5-HT1A receptor full agonist (pKi values are 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT2 and 5-HT3 receptors respectively). Possibly binds between the agonist binding site and the G protein interaction switch site, affecting the activation mechanism, and may display positive cooperativity. Anxiolytic following central administration in vivo.
5-aminolevulinic acid hydrochloride 
5-methoxytryptamine +   
5-nonyloxytryptamine 
5-nonyloxytryptamine oxalate 
9-aminoacridine hydrochloride 
acebutolol hydrochloride 
aceprometazine +  
aclacinomycin T hydrochloride 
acridine half-mustard dihydrochloride 
acridine orange  
acridine red 3B 
acridine yellow 
adinazolam  
alectinib hydrochloride 
alfuzosin hydrochloride 
almotriptan +   
almotriptan malate 
alosetron hydrochloride 
alpha-methylserotonin +   
alprazolam  
alprenolol hydrochloride 
alverine hydrochloride 
alvocidib hydrochloride 
amantadine hydrochloride 
amiloride hydrochloride +  
amineptine hydrochloride 
AMN082 dihydrochloride 
amodiaquine hydrochloride 
amorolfine hydrochloride 
amperozide  
amperozide hydrochloride 
ANA-12 
anagrelide hydrochloride 
ancitabine hydrochloride 
anileridine dihydrochloride 
apomorphine hydrochloride 
apraclonidine hydrochloride 
aripiprazole  
aripiprazole lauroxil 
arsphenamine 
atomoxetine hydrochloride  
auramine O  
azelastine hydrochloride 
bacampicillin hydrochloride 
bambuterol hydrochloride +  
benazepril hydrochloride 
benserazide hydrochloride 
benzphetamine hydrochloride 
bepridil hydrochloride 
bepridil hydrochloride monohydrate 
betaxolol hydrochloride +  
betazole dihydrochloride 
bevantolol hydrochloride +  
biliverdin hydrochloride 
biperiden hydrochloride 
Bismark brown Y 
bleomycin hydrochloride 
BRACO-19 
bromazine hydrochloride +  
bromhexine hydrochloride 
buclizine dihydrochloride 
buprenorphine hydrochlorie 
buspirone  
buspirone hydrochloride 
butenafine hydrochloride 
cadaverine dihydrochloride 
cariprazine hydrochloride 
carmoxirole hydrochloride 
carteolol hydrochloride 
cefepime hydrochloride 
cefmenoxime hydrochloride 
cefotiam dihydrochloride 
cefotiam hexetil dihydrochloride 
CGP 78608 hydrochloride 
chlordiazepoxide +   
chlordiazepoxide hydrochloride 
chlormezanone +  
chloroprocaine hydrochloride 
chlorpromazine hydrochloride 
chlorprothixene hydrochloride 
cimetidine hydrochloride 
cinacalcet hydrochloride 
cinanserin hydrochloride 
cinchocaine hydrochloride 
ciprofloxacin dihydrochloride 
ciprofloxacin hydrochloride (anhydrous) +  
cis-flupenthixol dihydrochloride 
cisapride  
clavulanic acid  
clenbuterol hydrochloride +  
clobazam  
clomipramine hydrochloride 
clonazepam  
clorazepate monopotassium +  
clorazepic acid 
cocaine hydrochloride 
colesevelam hydrochloride  
colestipol hydrochloride 
colforsin daropate hydrochloride  
conivaptan hydrochloride 
copanlisib dihydrochloride 
cyclazosin hydrochloride 
cyclizine hydrochloride 
cyclobenzaprine hydrochloride 
cycloguanil hydrochloride 
cyclopentolate hydrochloride +  
cycrimine hydrochloride +  
cyproheptadine hydrochloride (anhydrous) +  
D-lysine hydrochloride 
daclatasvir hydrochloride 
demeclocycline hydrochloride 
desipramine hydrochloride 
dexpropranolol hydrochloride 
dexrazoxane hydrochloride 
dextropropoxyphene hydrochloride 
dexverapamil hydrochloride +  
diazepam +   
dicyclomine hydrochloride 
didesethylflurazepam 
diethylpropion hydrochloride 
difenoxin hydrochloride 
dihydroergotamine +   
dihydroergotamine mesylate 
dihydroergotamine tartrate 
dilazep dihydrochloride 
dilevalol hydrochloride 
diltiazem hydrochloride 
diphenhydramine hydrochloride 
diphenoxylate hydrochloride 
diphenylpyraline hydrochloride 
dipivefrin hydrochloride 
dipotassium clorazepate 
DND-22 dye 
dobutamine hydrochloride 
dorzolamide hydrochloride  
dothiepin hydrochloride +  
doxapram hydrochloride (anhydrous) +  
doxycycline HCl +  
duloxetine hydrochloride +   
DuP-714 
dyclonine hydrochloride 
E-3810 
eflornithine hydrochloride monohydrate 
eletriptan  
eletriptan hydrobromide 
emetine dihydrochloride +  
emetine dihydrochloride hydrate 
encainide hydrochloride 
ent-diltiazem hydrochloride 
ent-tamsulosin hydrochloride +  
epinastine hydrochloride 
eprazinone hydrochloride 
ergotamine  
erlotinib hydrochloride  
esmolol hydrochloride 
esoxybutynin chloride 
estazolam  
etazolate  
ethambutol dihydrochloride 
ethidium homodimer 
ethylenediamine dihydrochloride 
famotidine hydrochloride 
fasudil hydrochloride +  
fenfluramine +   
fenfluramine hydrochloride +  
fingolimod hydrochloride  
flavoxate hydrochloride 
flibanserin 
fludiazepam 
flunitrazepam  
flupenthixol +   
flurazepam +   
fluvoxamine  
FR901469 hydrochloride 
garomefrine hydrochloride 
gemcitabine hydrochloride 
gevotroline hydrochloride 
glutaurine 
glutaurine zwitterion 
glutaurine(1-) 
glycinexylidide hydrochloride 
GR 127935 hydrochloride 
GS4012 
Hoffman's violet 
homofenazine 
hydrabamine dihydrochloride 
hydralazine hydrochloride 
hydrocortamate hydrochloride 
hydromorphone hydrochloride 
hydroxyzine +   
hydroxyzine hydrochloride 
ICR 340 
imipramine hydrochloride 
irinotecan hydrochloride (anhydrous) +  
ivabradine hydrochloride 
JTE-607 dihydrochloride 
ketamine hydrochloride +  
L-778,123 hydrochloride 
L-cysteine hydrochloride +  
L-lysine hydrochloride 
lanperisone hydrochloride 
levobunolol hydrochloride 
levopropoxyphene hydrochloride 
lidocaine hydrochloride +  
lisuride +   
lofepramine hydrochloride 
lomefloxacin hydrochloride 
loperamide hydrochloride 
lorcaserin hydrochloride +  
lorcaserin hydrochloride hemihydrate 
lorcaserin(1+) +  
lurasidone hydrochloride  
LY-165163 
LY-310762 hydrochloride 
LY404039 
lysergic acid diethylamide  
magenta II +  
mechlorethamine hydrochloride 
medetomidine hydrochloride +  
Mefloquine hydrochloride 
mefuparib hydrochloride 
memantine hydrochloride 
mepivacaine hydrochloride 
metformin hydrochloride +  
methadone hydrochloride 
methamphetamine hydrochloride 
methapyrilene hydrochloride 
methdilazine hydrochloride 
methixene hydrochloride 
methoctramine tetrahydrochloride  
methoxyphenamine hydrochloride 
methyl 5-aminolevulinate hydrochloride 
Methyl violet 2B 
methylamine hydrochloride 
methylphenidate hydrochloride 
metoclopramide dihydrochloride monohydrate 
metoclopramide hydrochloride +  
metronidazole hydrochloride 
mexiletine hydrochloride 
mianserin hydrochloride 
midazolam +   
midazolam hydrochloride 
midodrine hydrochloride 
minaprine hydrochloride 
minocycline hydrochloride 
mirtazapine  
mitoguazone hydrochloride +  
mitoxantrone dihydrochloride 
monoethylglycinexylidide hydrochloride 
moricizine hydrochloride 
morphine hydrochloride +  
mosapride 
moxifloxacin hydrochloride 
myrophine hydrochloride 
N(6)-\{2-[(1,2-diphenylhydrazinyl)carbonyl]-2-hydroxyhexanoyl\}-6-aminohexylammonium chloride 
N(6)-acetimidoyl-L-lysine dihydrochloride 
N(gamma)-nitro-L-arginine methyl ester hydrochloride 
N,N'-(p-xylylidene)bis(aminoguanidine) dihydrochloride 
N-(1-naphthyl)ethylenediamine dihydrochloride 
N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine hydrochloride 
N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide hydrochloride 
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide dihydrochloride 
N-\{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl\}-N-propylpropan-1-amine hydrochloride  
N-demethylmirtazapine 
N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-1-propanamine hydrochloride (1:1) 
N-methylquipazine +   
N-methylquipazine dimaleate 
Naftifine hydrochloride 
nalbuphine hydrochloride 
naloxone hydrochloride 
naltrexone hydrochloride +  
naratriptan +   
Naratriptan hydrochloride 
naxagolide hydrochloride 
nefazodone hydrochloride 
nemonapride 
neticonazole hydrochloride 
neutral red 
new fuchsin +  
nicotine +   
nimustine hydrochloride 
nordazepam  
NSC 23766 trihydrochloride 
olodaterol hydrochloride +  
orphenadrine hydrochloride 
oxazepam  
oxybuprocaine hydrochloride 
oxybutynin chloride 
oxycodone hydrochloride +  
oxymetazoline hydrochloride 
oxythiamine chloride hydrochloride 
palonosetron hydrochloride +  
pararosaniline +  
paroxetine +   
paroxetine hydrochloride 
paroxetine maleate 
pazopanib hydrochloride 
PD-153035 hydrochloride 
pethidine hydrochloride 
PF-670462  
phenazopyridine hydrochloride 
phenylephrine hydrochloride 
phenylhydrazine hydrochloride 
pibutidine hydrochloride 
pilocarpine hydrochloride 
pipamperone dihydrochloride 
pirenzepine hydrochloride 
piroheptine hydrochloride 
pivmecillinam hydrochloride 
PJ34 hydrochloride 
poly(allylamine hydrochloride) 
poly(diallylmethylammonium chloride) macromolecule +  
poly\{3-[(S)-5-amino-5-carboxyl-3-oxapentyl]-2,5-thiophenylene hydrochloride\} macromolecule +  
polyhexamethylene biguanide hydrochloride 
ponatinib hydrochloride 
pramipexole hydrochloride anhydrous +  
prazosin hydrochloride 
prilocaine hydrochloride 
prinomastat hydrochloride 
procainamide hydrochloride 
procarbazine hydrochloride 
procyclidine hydrochloride 
profenamine hydrochloride 
promazine hydrochloride 
promethazine hydrochloride 
propafenone hydrochloride 
propiomazine hydrochloride 
propranolol +   
propranolol hydrochloride  
protriptyline hydrochloride 
pseudoephedrine hydrochloride 
psilocin +  
psilocybin 
psilocybin(1-) 
puromycin dihydrochloride 
pyridoxal hydrochloride 
pyridoxamine dihydrochloride 
pyridoxamine hydrochloride 
pyridoxine hydrochloride 
quinacrine mustard dihydrochloride 
quinapril hydrochloride  
quininib hydrochloride 
raloxifene hydrochloride 
ranitidine hydrochloride 
remifentanil hydrochloride 
retaspimycin hydrochloride 
rilpivirine hydrochloride +  
ritanserin  
rizatriptan 
rolapitant hydrochloride (anhydrous) +  
rosanilin +  
RS 39604 hydrochloride 
sapropterin dihydrochloride 
SB 224289 hydrochloride 
selegiline hydrochloride 
sertraline hydrochloride 
SIS3 
SKF-96365 hydrochloride  
sotalol hydrochloride 
spectinomycin dihydrochloride 
spectinomycin hydrochloride hydrate 
spinosin 
spirit blue 
strychnine hydrochloride 
sumatriptan  
sumatriptan succinate 
synthalin 
talampicillin hydrochloride 
tamsulosin hydrochloride +  
tandospirone 
tandospirone citrate  
tegaserod +   
tegaserod maleate 
telavancin hydrochloride 
terazosin hydrochloride dihydrate 
terbinafine hydrochloride 
tetrahydrozoline hydrochloride 
tetrindole 
tetrindole hydrochloride 
tetrindole mesylate 
thiamine hydrochloride +  
thiocyclam hydrochloride 
thioridazine hydrochloride 
tiagabine hydrochloride 
tianeptine  
ticlopidine hydrochloride 
tilorone dihydrochloride 
tipiracil hydrochloride +  
tirofiban hydrochloride 
tranylcypromine  
tranylcypromine hydrochloride 
trazodone +   
trazodone hydrochloride 
triethanolamine hydrochloride 
trifluoperazine hydrochloride 
triflupromazine hydrochloride 
trimethylamine hydrochloride 
triprolidine hydrochloride (anh.) +  
tropisetron hydrochloride 
vanoxerine dihydrochloride  
varenicline  
varenicline tartrate 
venlafaxine hydrochloride  
vilazodone 
vilazodone hydrochloride 
vortioxetine  
vortioxetine hydrobromide 
xaliproden  
xanomeline  
xylazine hydrochloride 
Z-L-Lys-SBzl hydrochloride 
zaleplon  
ziprasidone hydrochloride hydrate 
ZM 323881 hydrochloride 
zolmitriptan  

Synonyms
Related Synonyms: 1-((4-Fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride ;   Formula=C24H27ClFN3O2 ;   InChI=1S/C24H26FN3O2.ClH/c1-30-21-10-7-18-3-2-4-23(22(18)17-21)28-15-13-27(14-16-28)12-11-26-24(29)19-5-8-20(25)9-6-19;/h2-10,17H,11-16H2,1H3,(H,26,29);1H ;   InChIKey=HWLZKPKZVOLFGK-UHFFFAOYSA-N ;   S 14506 ;   S 14506 hydrochloride ;   S 14506 monohydrochloride ;   S14506 hydrochloride ;   S14506 monohydrochloride ;   SMILES=Cl.COc1ccc2cccc(N3CCN(CCNC(=O)c4ccc(F)cc4)CC3)c2c1
Xrefs: CAS:135721-98-1
Xref Mesh: MESH:C092824
Xrefs: PMID:7698199 ;   Reaxys:8374093

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