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Term:
N-allyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide (CHEBI:64002)
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Parent Terms Term With Siblings Child Terms
(1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol 
(1R,3S)-3-(adamantan-1-yl)-1-(aminomethyl)-3,4-dihydroisochromene-5,6-diol hydrochloride  
(R)-SKF 38393 hydrobromide +  
(S)-SKF 38393 hydrobromide +  
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile hydrobromide +  
2-\{[(2E)-3-iodoprop-2-en-1-yl](propyl)amino\}tetralin-7-ol 
2-\{[(2E)-3-iodoprop-2-en-1-yl](propyl)amino\}tetralin-7-ol maleate 
2-hydroxy-17beta-estradiol +   
3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol hydrochloride 
4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline dimaleate  
4-phenylbutyric acid  
5-aminolevulinic acid +   
5-aminolevulinic acid hydrochloride 
6-bromoharmine hydrobromide 
abiraterone acetate 
acemetacin  
adefovir pivoxil  
alpha-N-dichloroacetyl-p-aminophenylserinol 
amantadine hydrochloride 
amifostine  
amodiaquine +   
ampiroxicam 
ancitabine  
apomorphine +   
aripiprazole lauroxil 
azaribine  
azathioprine  
azilsartan kamedoxomil 
azilsartan medoxomil 
bacampicillin +  
baicalin  
balsalazide +   
bambuterol +   
bambuterol hydrochloride +  
beclomethasone dipropionate 
benazepril  
bitolterol +  
bromocriptine +   
butane-1,4-diol +   
cabergoline  
cabozantinib malate 
capecitabine  
carbimazole  
cariprazine  
cariprazine hydrochloride 
carmoxirole  
carmoxirole hydrochloride 
cefamandole nafate 
cefditoren pivoxil 
cefotiam hexetil dihydrochloride 
cefotiam hexetil ester +  
cefpodoxime proxetil 
ceftaroline fosamil +  
ceftaroline fosamil acetate +  
ceftaroline fosamil acetate monohydrate 
ceftobiprole medocaril 
CGP 78608 hydrochloride 
clobenpropit dihydrobromide 
clorazepate monopotassium +  
clorazepic acid 
codeine +   
colistimethate 
colistimethate sodium 
dabigatran etexilate 
dabigatran etexilate methanesulfonate 
dacarbazine  
darifenacin hydrobromide 
dextilidine +  
dextromethorphan hydrobromide 
dihydroergotamine +   
dipivefrin 
dipotassium clorazepate 
dirithromycin 
dopamine receptor D1 agonist +   
doxifluridine  
droxicam 
droxidopa 
eletriptan hydrobromide 
enalapril +   
enalapril maleate 
etanidazole  
ethionamide +   
ethyl (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate 
famciclovir 
fenoldopam  
fenoterol hydrobromide 
fingolimod +  
fingolimod hydrochloride  
flucytosine  
fludarabine phosphate 
fluticasone furoate +  
fosamprenavir 
fosaprepitant 
fosaprepitant dimeglumine 
Fosfluconazole 
fosinopril  
fosinopril sodium 
gabapentin enacarbil 
gemcitabine +   
heroin  
hexa-L-lysine monohydrobromide 
imetit dihydrobromide 
imidapril +   
irinotecan  
irinotecan hydrochloride (anhydrous) +  
irinotecan hydrochloride hydrate 
isavuconazonium +  
isavuconazonium sulfate 
isopropyl unoprostone 
ixazomib citrate 
L-dopa +  
lamivudine  
latanoprost  
leflunomide  
lefradafiban 
lisuride +   
lovastatin +   
loxoprofen +   
lucanthone +   
lysergic acid diethylamide  
mestranol  
mesulergine  
metamizole 
metamizole sodium  
metergoline  
methyl 5-aminolevulinate +  
methyl 5-aminolevulinate hydrochloride 
metronidazole +   
metronidazole benzoate 
metronidazole hydrochloride 
midodrine  
mycophenolate mofetil 
myrophine +  
N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol  
N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide 
N-allyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide 
A hydrobromide salt prepared from N-allyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol and one equivalent of hydrogen bromide. High affinity, selective dopamine D1-like receptor agonist. Ki values are 3.2, 3.1, 186, 66, 335, 1167, 1251 and 1385 nM at recombinant D1, D5, D2, D3, D4, 5-HT2A, alpha1A and alpha1B receptors respectively. Stimulates adenylyl cyclase (EC50 = 65 nM) but not phosphoinositide hydrolysis. Induces extreme arousal and hyperlocomotion following subcutaneous administration in monkeys.
N-allyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepinium-7,8-diol 
N-methyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol  
N-methyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide 
N-methylquipazine dimaleate 
nabumetone  
NAN 190 hydrobromide  
naproxcinod 
nelarabine 
nepafenac 
nitroglycerin  
nitrosulindac 
O-formylcefamandole 
olsalazine 
olsalazine sodium 
oseltamivir +   
parecoxib  
pasireotide aspartate 
penamecillin 
pergolide  
pergolide mesylate 
pivampicillin 
pivmecillinam +  
poly(L-lysine) hydrobromide 
pramipexole  
pramipexole hydrochloride 
pramipexole hydrochloride anhydrous +  
prasugrel 
prednisone +   
proglumetacin +  
psilocybin 
psilocybin(1-) 
pyrazinecarboxamide  
quinapril  
quinpirole  
ramipril  
rilpivirine hydrochloride +  
rolitetracycline 
ropinirole  
rubitecan  
salicin +   
salsalate  
SB 224289 hydrochloride 
scopolamine hydrobromide (anhydrous) +  
selexipag 
simvastatin  
sodium phenylbutyrate 
sofosbuvir +  
soyasaponin III 
spirapril  
sulfanegen 
sulindac +   
suxibuzone  
talampicillin +  
tazarotene  
tedizolid phosphate 
temozolomide  
tenofovir alafenamide 
tenofovir alafenamide fumarate +  
tenofovir disoproxil +   
tenofovir disoproxil fumarate  
tiazofurine  
tilidine 
trandolapril  
travoprost 
tributyrin  
uracil +   
uridine triacetate 
valganciclovir 
vortioxetine hydrobromide 
ximelagatran  
zofenopril 
zofenopril calcium 

Synonyms
Exact Synonyms: 6-chloro-1-(3-methylphenyl)-3-(prop-2-en-1-yl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrobromide
Related Synonyms: 3-allyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrobromide ;   3-allyl-6-chloro-7,8-dihydroxy-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepinium bromide ;   6-chloro-7,8-dihydroxy-1-(3-methylphenyl)-3-(prop-2-en-1-yl)-2,3,4,5-tetrahydro-1H-3-benzazepinium bromide ;   Formula=C20H23BrClNO2 ;   InChI=1S/C20H22ClNO2.BrH/c1-3-8-22-9-7-15-16(11-18(23)20(24)19(15)21)17(12-22)14-6-4-5-13(2)10-14;/h3-6,10-11,17,23-24H,1,7-9,12H2,2H3;1H ;   InChIKey=CFWPKYBBXBANLU-UHFFFAOYSA-N ;   SKF 83822 hydrobromide ;   SMILES=Br.Cc1cccc(c1)C1CN(CCc2c1cc(O)c(O)c2Cl)CC=C
Xrefs: Reaxys:5198936 "Reaxys"

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.