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Term:
(-)-(11S,2'R)-erythro-mefloquine (CHEBI:63687)
Annotations: Rat: (9) Mouse: (8) Human: (9) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
(+)-(11R,2'S)-erythro-mefloquine +   
(+)-artemisinin +   
(-)-(11S,2'R)-erythro-mefloquine +   
An optically active form of [2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol having (-)-(11S,2'R)-erythro-configuration. An antimalarial agent, used in racemic form, which acts as a blood schizonticide; its mechanism of action is unknown.
(R)-7-butyl-6,8-dihydroxy-3-[(3E)-pent-3-en-1-yl]-3,4-dihydroisochromen-1-one 
2',4'-dihydroxy-3'-(2-hydroxy benzyl)-6'-methoxy chalcone 
3,15-di-O-acetylbruceolide 
3-(Z)-caffeoyllupeol 
5,7,3'-trihydroxy-4',5'-(2'''',2''''-dimethylpyran)-8,2'-di(3-methyl-2-butenyl)-(2S)-flavanone 
5-O-methylcelebixanthone 
7-deacetylgedunin 
8-azahypoxanthine 
acedapsone 
amburoside A 
amodiaquine +   
artemether  
arterolane 
arterolane maleate 
artesunate  
atovaquone  
bauhinoxepin F 
bauhinoxepin I 
bauhinoxepin J 
betulinic acid +   
bidebiline C 
bidebiline D 
bielschowskysin 
bipinnatone A 
bipinnatone B 
borrelidin  
bromophycolide A 
bruceolide +  
caesalpinin C 
caesalpinin D 
caesalpinin F 
callophycoic acid A 
callophycoic acid B 
callophycoic acid C 
callophycoic acid D 
callophycoic acid E 
callophycoic acid F 
callophycoic acid G 
callophycoic acid H 
callophycol A 
callophycol B 
caribenol A 
caribenol B 
caseargrewiin A 
caseargrewiin B 
caseargrewiin C 
caseargrewiin D 
cassiarin A 
cassiarin B 
celebixanthone +  
chloroquine +   
cochinchinone C 
conessine 
cordyheptapeptide A 
cordyol C 
crambescidin 800 
cryptolepine  
cycloguanil +  
dapsone +   
dehydroemetine 
dihydroartemisinin  
dioncopeltine A 
dioncophylline A 
dioncophylline C 
diuvaretin 
docetaxel anhydrous +  
doxycycline +   
dragomabin 
dragonamide A 
E64 
emetine +   
emetine dihydrochloride +  
emetine dihydrochloride hydrate 
Eunicea sesquiterpenoid 2 
Eunicea sesquiterpenoid 3 
eurycomanone  
exiguaflavanone A 
exiguaflavanone B 
gedunin +   
gutolactone 
hirsutellide A 
hydroxychloroquine  
isariotin F 
isonordoperoxide 
lactucin +  
lactucopicrin 
leachianone A 
longirostrerone A 
longirostrerone B 
longirostrerone C 
lumefantrine 
lycorine  
manzamine A +  
mefloquine  
methylene blue  
minquartynoic acid 
mollicellin B 
mollicellin C 
mollicellin E 
mollicellin J 
mollicellin K 
mollicellin L 
mollicellin M 
nardoperoxide 
neurolenin A 
neurolenin B 
neurolenin C 
neurolenin D 
norcaesalpinin D 
norcaesalpinin E 
norlichexanthone 
nostocarboline 
phomoxanthone A 
phomoxanthone B 
physalin B 
physalin D 
physalin F 
physalin G 
piperaquine 
pracinostat 
primaquine  
proguanil  
pyrimethamine  
quercetin-7-O-[alpha-L-rhamnopyranosyl(1->6)-beta-D-galactopyranoside] 
quinacrine +   
quinidine +   
quinine +   
quinine sulfate +  
quinine(1+) +   
robustaside D 
robustaside E 
robustaside F 
robustaside G 
samaderine B 
samaderine E 
samaderine X 
samaderine Z 
scutianthraquinone A 
scutianthraquinone B 
scutianthraquinone C 
simalikalactone D 
sophoraflavanone G 
sulfadoxine 
tafenoquine 
triacsin C  
triclosan  
venturamide A 
venturamide B 
WLL-vs 

Synonyms
Exact Synonyms: (S)-[2,8-bis(trifluoromethyl)quinolin-4-yl][(2R)-piperidin-2-yl]methanol
Related Synonyms: (-)-Mefloquine ;   Formula=C17H16F6N2O ;   InChI=1S/C17H16F6N2O/c18-16(19,20)11-5-3-4-9-10(15(26)12-6-1-2-7-24-12)8-13(17(21,22)23)25-14(9)11/h3-5,8,12,15,24,26H,1-2,6-7H2/t12-,15+/m1/s1 ;   InChIKey=XEEQGYMUWCZPDN-DOMZBBRYSA-N ;   SMILES=O[C@H]([C@H]1CCCCN1)c1cc(nc2c(cccc12)C(F)(F)F)C(F)(F)F ;   [(11S,2'R)-2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol
Xrefs: CAS:51742-87-1 ;   LINCS:LSM-5525 ;   Reaxys:5629059
Cyclic Relationships: is_enantiomer_of CHEBI:63684

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