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(+)-(12E,2S,3S,4R,5R,6R,9S,11S,15R)-3-benzoyloxy-5,6-epoxylathyr-12-en-15-ol-14-one 
(+)-(12E,2S,3S,4R,5R,6R,9S,11S,15R)-3-cinnamoyloxy-5,6-epoxylathyr-12-en-15-ol-14-one 
(+)-(5E,12E,2S,3S,4S,9S,11S,15R)-3-cinnamoyloxylathyra-5,12-dien-15-ol-14-one 
(+)-cis-isohumulone 
(-)-(12E,2S,3S,4R,5R,6R,9S,11S,15R)-3-acetoxy-5,6-epoxylathyr-12-en-15-ol-14-one 
(-)-(6Z,12E,2S,3S,4R,5R,9S,11S,15R)-3-cinnamoyloxylathyra-6,12-diene-5,15-diol-14-one 
(-)-(6Z,12E,2S,3S,4R,5R,9S,11S,15R)-5-cinnamoyloxylathyra-6,12-diene-3,15-diol-14-one 
(-)-anisomycin  
(-)-microdiplodiasolol 
(16alpha,20R,24R)-24N,25-carbamoyloxy-2,16,20-trihydroxycucurbita-1,5-diene-3,11,22-trione 2-O-beta-D-glucopyranoside 
(16alpha,20R,24S)-2,16,20,25-tetrahydroxy-24-methoxycucurbita-1,5-diene-3,11,22-trione 2-O-beta-D-glucopyranoside 
(1S)-1,23,25-trihydroxy-24-oxocalciol 
(1S)-1,25-dihydroxy-24-oxocalciol 
(22E,24R)-3beta,5alpha,9alpha-trihydroxyergosta-7,22-dien-6-one 
(22E,24R)-3beta,5alpha-dihydroxyergosta-7,22-dien-6-one 
(4aS,5aR,12aS)-10,12a-dihydroxy-1,3,11,12-tetraoxo-4,4a,5,5a,6,11a-hexahydrotetracene-2-carboxamide 
(4R,12aR)-4,7-bis(dimethylamino)-10,12a-dihydroxy-1,3,11,12-tetraoxo-4,4a,5,5a,6,11a-hexahydrotetracene-2-carboxamide 
(4S,4aR,5S,12aS)-7-chloro-4-(dimethylamino)-5,10,12a-trihydroxy-6-methylene-1,3,11,12-tetraoxo-4a,5,5a,11a-tetrahydro-4H-tetracene-2-carboxamide 
(4S,4aS,5aR,12aS)-9-[[2-(tert-butylamino)-1-oxoethyl]amino]-4,7-bis(dimethylamino)-10,12a-dihydroxy-1,3,11,12-tetraoxo-4,4a,5,5a,6,11a-hexahydrotetracene-2-carboxamide 
(4S,4aS,5aR,6S,12aS)-7-chloro-4-(dimethylamino)-6,10,12a-trihydroxy-6-methyl-1,3,11,12-tetraoxo-4a,5,5a,11a-tetrahydro-4H-tetracene-2-carboxamide 
(4S,4aS,6S,12aS)-7-chloro-4-(dimethylamino)-6,10,12a-trihydroxy-6-methyl-1,3,11,12-tetraoxo-4a,5,5a,11a-tetrahydro-4H-tetracene-2-carboxamide 
(R)-blebbistatin 
(R)-iclaprim +  
(R)-temafloxacin +  
(S)-2-acetyl-2-hydroxybutanoic acid 
(S)-blebbistatin 
(S)-iclaprim +  
(S)-temafloxacin +  
1-hydroxylimonen-2-one +  
1-O-demethyl-6-deoxydoxorubicin 
11-deoxycortisol  
11a-hydroxy-7-iodotetracycline zwitterion 
11a-hydroxychlortetracycline zwitterion 
11a-hydroxytetracycline 
11a-hydroxytigecycline(1+) 
11beta,17alpha,21-trihydroxypregnenolone 
12-dehydrotetracycline 
12-deoxyphorbol 20-acetate 13-(2-methylbutanoate) 
12-deoxyphorbol-13-(3E,5E-decadienoate) 
16-hydroxyphorbol 13-decanoate 12-palmitate 
16alpha,17alpha-dihydroxypregnenolone 
17,21-dihydroxy-5beta-pregnane-3,11,20-trione  
17-epi-17-hydroxyazadiradione 
17-hydroxyazadiradione 
17-hydroxypregnenolone 3-sulfate 
17-hydroxyprogesterone 3-O-(carboxymethyl)oxime 
17alpha,21-dihydroxypregnenolone 
17alpha-hydroxypregn-5-ene-3,20-dione 
17alpha-hydroxypregnenolone +   
17alpha-hydroxyprogesterone  
2-acetyllactic acid +  
2-hydroxy-17beta-estradiol +   
21-acetoxy-11beta,17-dihydroxy-6alpha-methylpregn-4-ene-3,20-dione 
21-dehydrocortisol  
21-dehydrocortisone 
21beta-hydroxyolean-12-en-3-one 
23(S),25-dihydroxy-24-oxovitamin D3 
23,24-dihydrocucurbitacin +  
23,24-dihydrocucurbitacin B 
23,24-dihydrocucurbitacin D 
23,24-dihydrocucurbitacin E 
25-hydroxy-24-oxocalciol 
3'-deamino-3'-(3-cyanomorpholin-4-yl)doxorubicin  
3'-deoxysappanone B 
3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol hydrochloride 
3-farnesyl-3-hydroxy-2-methyl-1-oxo-1lambda(5)-quinolin-4-one 
3-hydroxy-2-methyl-3-phytyl-2,3-dihydro-1,4-naphthoquinone 
3-hydroxy-3-methyl-2-oxobutanoic acid 
3-hydroxy-3-methyl-2-oxopentanoic acid +  
4',5'-dihydro-11,5'-dihydroxy-4'-methoxytephrosin 
4'-deoxy-4'-iododoxorubicin 
4'-epidoxorubicin  
4,5-dihydrocortisone +   
4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline dimaleate  
4-(dimethylamino)-5,10,12a-trihydroxy-6-methyl-1,3,11,12-tetraoxo-4,4a,5,5a,6,11a-hexahydrotetracene-2-carboxamide 
4-(dimethylamino)-6,10,12a-trihydroxy-6-methyl-1,3,11,12-tetraoxo-4a,5,5a,11a-tetrahydro-4H-tetracene-2-carboxamide 
4-\{((R)-2-Carboxy-3-methoxymethyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-en-7-ylcarbamoyl)-[(Z)-methoxyimino]-methyl\}-thiazol-2-yl-ammonium +  
4-amino-4-de(dimethylamino)anhydrotetracycline 
4-Aminoanhydrochlortetracycline 
4-de(dimethylamino)-4-oxoanhydrotetracycline 
4-Dedimethylamine-4-oxo-anhydro-7-Cl-tetracycline 
4-hydroxy-2-methyl-3-oxo-[(2E,6E)-farnesyl]-3,4-dihydroquinoline-1-oxide 
4-phenylbutyric acid  
4alpha-phorbol 12,13-didecanoate 
5-aminolevulinic acid +   
5-aminolevulinic acid hydrochloride 
5-chloro-7-iodoquinolin-8-ol  
5a,11a-Dehydrochlortetracycline 
5a,11a-dehydrooxytetracycline 
5beta-dihydrocortisol 
6-methylprednisolone +   
6alpha-fluoro-17-hydroxycorticosterone 21-acetate 
6alpha-methylprednisolone +   
6beta,16alpha,17alpha-trihydroxyprogesterone 
6beta-hydroxycortisol  
6beta-hydroxycortisone 
7-chloro-4-(dimethylamino)-6,10,12a-trihydroxy-1,3,11,12-tetraoxo-4,4a,5,5a,6,11a-hexahydrotetracene-2-carboxamide 
7-epi-cylindrospermopsin 
8-demethyl-8-(2,3,4-O-trimethyl-alpha-L-rhamnosyl)tetracenomycin C 
8-demethyl-8-(2,3-O-dimethyl-alpha-L-rhamnosyl)tetracenomycin C 
8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)tetracenomycin C 
8-demethyl-8-(alpha-L-rhamnosyl)tetracenomycin C 
8-demethyltetracenomycin C 
9-fluoro-11beta,17,21-trihydroxy-2alpha-methylpregn-4-ene-3,20-dione 21-acetate 
a tetracycline zwittterion +  
abiraterone acetate 
acemetacin  
adefovir pivoxil  
alatolide 
alclometasone 
algestone +  
alpha-N-dichloroacetyl-p-aminophenylserinol 
amifostine  
amikacin  
amikacin disulfate 
amodiaquine +   
amoxicillin +   
amoxicillin trihydrate +   
amphotericin B +   
ampicillin +   
ampiroxicam 
ancitabine  
Anhydrochlortetracycline 
anhydrotetracycline +  
anhydrotetracycline zwitterion 
antileishmanial agent +   
antimycobacterial drug +   
antiplasmodial drug +   
antitreponemal drug +  
antitrichomonal drug +   
apramycin 
arasertaconazole +   
arbekacin +  
aripiprazole lauroxil 
asperfuranone 
Augmentin  
avibactam 
avibactam sodium +  
avilamycin A 
avilamycin A precursor 
Avycaz 
azanigerone E 
azaribine  
azathioprine  
azilsartan kamedoxomil 
azilsartan medoxomil 
azithromycin +   
azlocillin 
aztreonam +   
bacampicillin +  
baicalin  
balsalazide +   
bambuterol +   
bambuterol hydrochloride +  
beclomethasone +   
beclomethasone dipropionate 
benazepril  
benznidazole 
benzyl isothiocyanate  
benzylpenicillin +   
berkeleydione 
berkeleyone A 
berkeleyone B 
berkeleyone C 
berkeleytrione 
betamethasone +   
betamethasone acetate 
betamethasone phosphate 
betamethasone sodium phosphate 
biapenem 
bitolterol +  
blasticidin S +  
blebbistatin +   
BMS-192548 
bortezomib  
brodimoprim 
bruceolline M 
butane-1,4-diol +   
cabozantinib malate 
calotropone 
capecitabine  
carbapenem MM22383 
carbenicillin +  
carbimazole  
caribenol B 
carminomycin +  
carumonam 
caudatin-3-O-beta-cymaropyranoside 
cefaclor  
cefadroxil +   
cefaloridine  
cefalotin +   
cefamandole +  
cefamandole nafate 
cefamandole sodium 
cefatrizine 
cefazedone 
cefazolin  
cefcapene 
cefdaloxime 
cefdinir  
cefditoren +  
cefditoren pivoxil 
cefepime  
cefepime hydrochloride 
cefiderocol 
cefixime  
cefmenoxime +  
cefmetazole  
cefodizime 
cefonicid  
cefoperazone  
ceforanide 
cefotaxime  
cefotetan  
cefotetan disodium 
cefotiam +   
cefotiam dihydrochloride 
cefotiam hexetil dihydrochloride 
cefotiam hexetil ester +  
cefoxitin  
cefpiramide 
cefpodoxime +   
cefpodoxime proxetil 
cefprozil 
cefsulodin 
ceftaroline +  
ceftaroline fosamil +  
ceftaroline fosamil acetate +  
ceftaroline fosamil acetate monohydrate 
ceftazidime +   
ceftibuten +   
ceftibuten dihydrate 
ceftizoxime  
ceftobiprole medocaril 
ceftriaxone  
cefuzonam 
cephalexin +   
cephalexin monohydrate 
cephapirin 
cephapirin sodium 
cephradine  
cethromycin 
CGP 78608 hydrochloride 
chaetoxanthone A 
chaetoxanthone B 
chaetoxanthone C 
chermesinone A 
chloramphenicol +   
chlorphenesin +   
chlorquinaldol 
chlortetracycline  
cinoxacin  
ciprofloxacin +   
ciprofloxacin dihydrochloride 
ciprofloxacin hydrochloride (anhydrous) +  
ciprofloxacin hydrochloride hydrate 
clarithromycin  
clavulanic acid 
clobetasol +   
clometocillin 
clomocycline 
clorazepate monopotassium +  
clorazepic acid 
cloxacillin  
co-trimoxazole  
coccidiostat +   
codeine +   
colistimethate 
colistimethate sodium 
comazaphilone D 
comazaphilone E 
comazaphilone F 
cortancyl 
cortisol +   
cortisol 21-acetate 
cortisol 21-sulfate 
cortisol phosphate 
cortisone +   
cortistatin D 
cryptopleurine 
cucurbitacin B +   
cucurbitacin D 
cucurbitacin E +   
cucurbitacin E 2-O-beta-D-glucopyranoside 
cucurbitacin I +   
cucurbitacin I 2-O-beta-D-glucopyranoside 
cucurbitacin J +  
cucurbitacin J 2-O-beta-D-glucopyranoside 
cucurbitacin K 2-O-beta-D-glucopyranoside 
curamycin A 
cyclacillin 
cycloguanil +  
cycloheximide  
cylindrospermopsin  
cyproterone +   
cytochalasin D  
dabigatran etexilate 
dabigatran etexilate methanesulfonate 
dacarbazine  
dalbavancin 
daphnetoxin 
daptomycin 
demeclocycline +   
demeclocycline hydrochloride 
deoxycylindrospermopsin 
desmethylanhydrotetracycline 
dexamethasone phosphate  
dextilidine +  
diallyl trisulfide  
dibekacin +  
dicloxacillin  
diflorasone +   
difloxacin 
dimetridazole 
dipivefrin 
dipotassium clorazepate 
dirithromycin 
DMG-MINO 
doxifluridine  
doxorubicin +   
doxycycline +   
doxycycline hyclate 
doxycycline monohydrate 
droxicam 
droxidopa 
dTDP-4-dehydro-3-methyl-2,6-dideoxy-beta-L-glucose 
dzununcanone 
elloramycin A 
emetine +   
enalapril +   
enalapril maleate 
enoxacin  
epi-isochromophilone II 
ertapenem 
ertapenem sodium 
etanidazole  
ethionamide +   
ethyl (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate 
Euphorbia diterpenoid 3 
famciclovir 
fenticonazole 
fenticonazole nitrate 
fidaxomicin 
finafloxacin 
fingolimod +  
fingolimod hydrochloride  
fleroxacin 
flomoxef 
flucloxacillin +   
flucytosine  
fludarabine phosphate 
fludrocortisone acetate 
flumethasone +   
flumethasone pivalate 
fluorometholone +   
flurithromycin 
fluticasone furoate +  
forskolin +   
fosamprenavir 
fosaprepitant 
fosaprepitant dimeglumine 
Fosfluconazole 
fosinopril  
fosinopril sodium 
framycetin +   
fumagillin +   
furagin 
furaltadone 
furazolidone  
fusidic acid  
gabapentin enacarbil 
garenoxacin 
gemcitabine +   
gemifloxacin +  
geneticin  
GM 193663 
guamecycline 
guignardone N 
harziphilone 
heroin  
hetacillin 
hexamethylenetetramine +  
humulone 
hydrocortamate +  
hydrocortisone caproate 
hydrocortisone succinate  
iclaprim 
ikarugamycin 
imidapril +   
imidocarb 
imipenem +   
iodtetracycline(1-) +  
irinotecan  
irinotecan hydrochloride (anhydrous) +  
irinotecan hydrochloride hydrate 
isariotin F 
isavuconazonium +  
isavuconazonium sulfate 
isoconazole  
isoconazole nitrate 
isopropyl unoprostone 
ivermectin  
ixazomib citrate 
josamycin  
kanamycin A sulfate 
kasugamycin 
kidjoranin-3-O-alpha-diginopyranosyl-(1->4)-beta-cymaropyranoside 
kidjoranin-3-O-beta-digitoxopyranoside 
L-dopa +  
L-thialysine 
lamivudine  
latanoprost  
leflunomide  
lefradafiban 
leucosesterlactone 
leucosesterterpenone 
levofloxacin  
linezolid  
lonchocarpenin 
longirostrerone B 
loracarbef 
lovastatin +   
loxoprofen +   
lucanthone +   
lycorine  
lymecycline 
malachite green cation +   
marbofloxacin 
mecillinam +  
meclocycline  
medroxyprogesterone +   
megestrol +   
meropenem +   
meropenem trihydrate 
mestranol  
metamizole 
metamizole sodium  
methacycline 
methicillin +  
methyl 5-aminolevulinate +  
methyl 5-aminolevulinate hydrochloride 
methyl prednisolone-16-carboxylate +  
methyl prednisolone-16alpha-carboxylate 
methylprednisolone acetate 
metronidazole +   
metronidazole benzoate 
metronidazole hydrochloride 
mezlocillin 
microdiplodiasol 
midodrine  
miltefosine  
minocycline +   
mometasone +   
moxalactam 
moxifloxacin  
moxifloxacin hydrochloride 
mupirocin 
Mupirocin calcium hydrate 
mycophenolate mofetil 
myrophine +  
myrothenone A 
N-allyl-1-phenyl-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide 
N-allyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide 
N-methyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide 
N-methylquipazine dimaleate 
nabumetone  
nadifloxacin +  
nafcillin  
nalidixic acid  
naproxcinod 
nelarabine 
nemorubicin  
nepafenac 
neurolenin A 
neurolenin B 
neurolenin C 
neurolenin D 
nifurtoinol 
nitarsone 
nitrofurantoin  
nitrofurazone  
nitroglycerin  
nitrosulindac 
norfloxacin  
O-formylcefamandole 
ochracenomicin A 
ofloxacin +   
olsalazine 
olsalazine sodium 
omacetaxine mepesuccinate 
oritavancin +  
oritavancin bisphosphate 
ornidazole  
oseltamivir +   
otophylloside B 
oxacillin +   
oxolinic acid 
oxytetracycline  
parecoxib  
paromomycin +   
paromomycin sulfate 
pasireotide aspartate 
pefloxacin +  
pefloxacin mesylate 
penamecillin 
phorbol +   
phorbol 12,13-dibutanoate  
phorbol 13-acetate 12-myristate  
phorbol 13-butanoate 
phorbol 13-decanoate 12-tiglate 
pipacycline 
pipemidic acid  
piperacillin +   
piromidic acid 
pivampicillin 
pivmecillinam +  
polyketomycin 
polypodine B 
potassium clavulanate +   
pppA2'p5'A2'p5'A 
prasugrel 
preaustinoid A 
preaustinoid A1 
prednisolone +   
prednisolone-16-carboxylic acid +  
prednisolone-16alpha-carboxylic acid +  
prednisone +   
Pretetramid +  
pretetramide +  
pristinamycin 
pristinamycin IA +  
pristinamycin IIA +  
proglumetacin +  
proguanil  
prontosil  
pseudobaptigenin +  
pseudobaptigenin(1-) 
psilocybin 
psilocybin(1-) 
pterolinus I 
puromycin +   
purpurquinone A 
purpurquinone B 
purpurquinone C 
pyrazinecarboxamide  
pyrimethamine  
quinapril  
ramipril  
ribostamycin +  
ribostamycin sulfate 
rifampicin +   
rilpivirine hydrochloride +  
ristocetin 
robustaside E 
rolitetracycline 
A derivative of tetracycline in which the amide function is substituted with a pyrrolidinomethyl group.
ronidazole 
rosoxacin 
roxarsone  
roxithromycin +   
rubitecan  
salicin +   
salicylhydroxamic acid  
salsalate  
sancycline 
sapintoxin D 
SB 224289 hydrochloride 
selexipag 
sertaconazole  
sertaconazole nitrate 
silver(1+) sulfadiazinate 
simvastatin  
sirolimus +   
sodium phenylbutyrate 
sofosbuvir +  
sordarin +  
soyasaponin III 
spectinomycin 
spectinomycin dihydrochloride 
spectinomycin hydrochloride hydrate 
spiramycin I 
spiramycin II 
spirapril  
streptomycin +   
sulfacetamide 
sulfachloropyridazine 
sulfadiazine  
sulfadoxine 
sulfamazone 
sulfamethazine  
sulfanegen 
sulfaperin 
sulfaphenazole  
sulfathiourea 
sulfisoxazole +   
sulfisoxazole diolamine 
sulindac +   
suxibuzone  
talampicillin +  
TAN-1612 
tavaborole 
tazarotene  
tedizolid 
tedizolid phosphate 
teicoplanin  
telavancin +  
telavancin hydrochloride 
temafloxacin 
temozolomide  
tenofovir alafenamide 
tenofovir alafenamide fumarate +  
tenofovir disoproxil +   
tenofovir disoproxil fumarate  
tenuazonic acid 
tetracenomycin C +  
tetracenomycin X 
tetracycline +   
tetracycline zwitterion 
tetrahydrocortisol 
thiostrepton  
thiram  
tiamulin  
tiazofurine  
ticarcillin 
tigecycline +   
tilidine 
tinidazole  
tinyatoxin 
tixocortol +  
tixocortol pivalate 
trandolapril  
travoprost 
triamcinolone +   
tributyrin  
trichanolide 
trichodermin 
trigoheterin E, (rel)- +  
trimethoprim +   
trovafloxacin  
trovafloxacin mesylate 
trypanocidal drug +   
uracil +   
uridine triacetate 
valganciclovir 
vancomycin +   
virginiamycin 
virginiamycin S1 +  
viridicatumtoxin 
xibornol 
ximelagatran  
zofenopril 
zofenopril calcium 

Synonyms
Exact Synonyms: (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(pyrrolidin-1-ylmethyl)-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
Related Synonyms: Formula=C27H33N3O8 ;   InChI=1S/C27H33N3O8/c1-26(37)13-7-6-8-16(31)17(13)21(32)18-14(26)11-15-20(29(2)3)22(33)19(24(35)27(15,38)23(18)34)25(36)28-12-30-9-4-5-10-30/h6-8,14-15,20,31,33-34,37-38H,4-5,9-12H2,1-3H3,(H,28,36)/t14-,15-,20-,26+,27-/m0/s1 ;   InChIKey=HMEYVGGHISAPJR-IAHYZSEUSA-N ;   N-(1-Pyrrolidinylmethyl)-tetracycline ;   N-(Pyrrolidinomethyl)tetracycline ;   Pyrrolidino-methyl-tetracycline ;   Reverin ;   SMILES=[H][C@@]12C[C@@]3([H])C(C(=O)c4c(O)cccc4[C@@]3(C)O)=C(O)[C@]1(O)C(=O)C(C(=O)NCN1CCCC1)=C(O)[C@H]2N(C)C ;   Synterin ;   rolitetraciclina ;   rolitetracyclinum
Xrefs: CAS:751-97-3 "ChemIDplus" ;   CAS:751-97-3 "KEGG DRUG" ;   DrugBank:DB01301 ;   Drug_Central:2399 "DrugCentral" ;   KEGG:D02282 ;   PMID:1650428 "Europe PMC" ;   Patent:US3104240 ;   Reaxys:73191 "Reaxys" ;   Wikipedia:Rolitetracycline

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.