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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
(+-)-menthol 
(-)-menthol +  
(1R,9bR)-9b-fluoro-1,2,5,10-tetrahydroxy-1,9a,11a-trimethyl-2H,3H,3aH,3bH,4H,5H,8H,9H,10H,11H-cyclopenta[a]phenanthren-7-one 
(1S,5aR,9bR)-9b-fluoro-1-hydroxy-1,9a,11a-trimethyl-2H,3H,3aH,3bH,4H,5H,5aH,6H,8H,9H-cyclopenta[a]phenanthren-7-one 
(1S,5aS,9bR)-9b-fluoro-1-hydroxy-1,9a,11a-trimethyl-2H,3H,3aH,3bH,4H,5H,5aH,6H,8H,9H-cyclopenta[a]phenanthren-7-one 
(1S,9bR)-9b-fluoro-1,10-dihydroxy-1,9a-dimethyl-2H,3H,3bH,4H,5H,8H,9H,10H,11H-cyclopenta[a]phenanthren-7-one 
(1S,9bR)-9b-fluoro-1,5,10-trihydroxy-1,9a-dimethyl-2H,3H,3bH,4H,5H,5aH,6H,8H,9H,10H,11H-cyclopenta[a]phenanthren-7-one 
(1S,9bR)-9b-fluoro-1-hydroxy-1,9a,11a-trimethyl-decahydrocyclopenta[a]phenanthrene-5,7,10-trione 
(22E)-24nor-cholesta-1,4,22-trien-3-one 
(3S)-3-[(2S)-2-amino-4-hydroxy-3-oxobutyl]pyrrolidin-2-one 
(7R,9bR)-9b-fluoro-1,1,9a-trimethyl-2H,3H,3bH,4H,5H,7H,8H,9H,10H,11H-cyclopenta[a]phenanthrene-7,10-diol 
(8S,9S,10R,11S,13S,14R,17R)-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one 
(8S,9S,10R,11S,13S,14R,17S)-11-hydroxy-17-(2-hydroxy-1-oxoethyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one 
(9bR)-9b-fluoro-5,10-dihydroxy-1,1,9a-trimethyl-2H,3H,3bH,4H,5H,8H,9H,10H,11H-cyclopenta[a]phenanthren-7-one 
(9R)-9-chloro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one 
1,3-dihydroxybutan-2-one 
1-hydroxybutan-2-one 
1-O-demethyl-6-deoxydoxorubicin 
1-propyl-2-hydroxyacetylpyrrole 
11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one 
11,21-dioxoprogesterone 
11-dehydrocorticosterone  
11-deoxycorticosterone +   
11-deoxycorticosterone-21-hemisuccinate 
11-deoxycortisol  
11alpha-hydroxyprogesterone +  
11alpha-hydroxyprogesterone hemisuccinate +  
11beta,17alpha,21-trihydroxypregnenolone 
11beta-hydroxy-17beta-estradiol 
11beta-hydroxyandrost-4-ene-3,17-dione 
11beta-hydroxyprogesterone 
11beta-hydroxytestosterone 
12alpha-Methylpregna-4,9(11)-diene-3,20-dione 
15beta-hydroxyprogesterone 
16,17-didehydropregnenolone +  
16,17-didehydropregnenolone 3-beta-D-glucoside 
16,17-didehydroprogesterone 
16alpha,17alpha-dihydroxyprogesterone acetophenide +  
16alpha-Hydroxycorticosterone 
16beta-fluoro-17beta-hydroxyandrost-4-en-3-one propionate 
16beta-hydroxyestradiol +  
16beta-methylpregn-4-ene-3,20-dione 
17,21-dihydroxy-5beta-pregnane-3,11,20-trione  
17,21-Epoxy-9-fluoro-11beta-hydroxypregn-4-ene-3,20-dione 
17-hydroxy-17-(2-hydroxy-1-oxoethyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one 
17-hydroxypregnenolone 3-sulfate 
17-hydroxyprogesterone 3-O-(carboxymethyl)oxime 
17alpha,21-dihydroxypregnenolone 
17alpha-hydroxypregn-5-ene-3,20-dione 
18-hydroxycorticosterone 
19-hydroxydeoxycorticosterone 
1S,7R,9bR)-9b-fluoro-1,9a,11a-trimethyl-2H,3H,3aH,3bH,4H,5H,7H,8H,9H,10H,11H-cyclopenta[a]phenanthrene-1,7,10-triol 
2,4'-dihydroxyacetophenone 
2,5-dioxo-1-pyrrolidinyl 6-(6-\{3-[(progesterone-4-yl)thiopropionyl]aminohexanoyl\}amino)hexanoate 
2-hydroxyacetophenone 
20beta-dihydrocortisol 
21-acetoxy-11beta,17-dihydroxy-6alpha-methylpregn-4-ene-3,20-dione 
21-dehydrocortisol  
21-dehydrocortisone 
21-deoxycortisol 
21-Hydroxy-5beta-pregnane-3,11,20-trione 
21-hydroxy-C21-steroid 
21-hydroxypregnenolone +  
21-hydroxypregnenolone disulfate 
22-deoxy-20,21-dihydroxyecdysone 
24-methylenecholesta-1,4-dien-3-one 
2alpha-fluoro-17beta-hydroxyandrost-4-en-3-one 
2beta,21-Dihydroxypregn-4-ene-3,20-dione 
3'-deamino-3'-(3-cyanomorpholin-4-yl)doxorubicin  
3,6-Dimethoxy-19-norpregna-1,3,5,7,9-pentaen-20-one 
3-(progesterone-4-yl)thiopropionic acid 
3-(progesterone-7alpha-yl)thiopropionic acid 
3-hydroxypregnan-20-one +   
3-hydroxypyruvic acid  
3-oxo-23,24-bisnorchola-1,4-dien-22-oic acid 
3a,7b,21-trihydroxy-5b-cholanoic acid 
3alpha,11beta,21-Trihydroxy-20-oxo-5beta-pregnan-18-al 
3alpha,12alpha-dihydroxy-5beta-pregnan-20-one diacetate 
3alpha,17alpha,21-Trihydroxy-5beta-pregnan-20-one 
3alpha,20alpha,21-Trihydroxy-5beta-pregnane-11-one 
3alpha,21-Dihydroxy-5beta-pregnane-11,20-dione 
3beta,21-Dihydroxy-4,4,14-trimethyl-5alpha-pregn-8-en-20-one 
3beta-hydroxy-16alpha,17alpha-epoxypregnenolone +  
3beta-hydroxy-16alpha,17alpha-epoxypregnenolone 3-beta-D-glucoside 
3beta-hydroxy-5alpha-pregnan-20-one hemisuccinate 
3beta-hydroxy-5beta-pregnan-20-one hemisuccinate 
4'-deoxy-4'-iododoxorubicin 
4'-epidoxorubicin  
4,5-dihydrocortisone +   
4,5alpha-dihydrocortisone 
4-Methyl-4-aza-5-pregnene-3,20-dione 
4-pregnen-20,21-diol-3-one 
4-pregnen-3beta-ol-20-one 
4-Pregnene-16alpha,21-diol-3,20-dione 
5-alpha-THDOC  
5alpha-Dihydrodeoxycorticosterone 
5alpha-pregnane-3,20-dione  
5beta-dihydroaldosterone 
5beta-dihydrocorticosterone 
5beta-dihydrocortisol 
5beta-dihydrodeoxycorticosterone 
5beta-pregn-11-ene-3,20-dione 
5beta-pregnane-3,20-dione 
6-(6-\{3-[(progesterone-4-yl)thiopropionyl]aminohexanoyl\}amino)hexanoic acid 
6-\{3-[(progesterone-4-yl)thiopropionyl]amino\}hexanoic acid 
6-methylprednisolone +   
6alpha-fluoro-17-hydroxycorticosterone 21-acetate 
6alpha-Fluoroprednisolone 
6alpha-Hydroxycortisol 
6alpha-methylprednisolone +   
6beta,16alpha,17alpha-trihydroxyprogesterone 
6beta-hydroxycortisol  
6beta-hydroxycortisone 
6beta-hydroxyprogesterone +  
6beta-hydroxyprogesterone hemisuccinate 
7alpha-hydroxypregnenolone 
9,11alpha-epoxypregn-4-ene-3,20-dione 
9-fluoro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one 
9-fluoro-11beta,17,21-trihydroxy-2alpha-methylpregn-4-ene-3,20-dione 21-acetate 
9-Fluoro-11beta,21-dihydroxy-16alpha,17-(isopropylidenedioxy)pregn-4-ene-3,20-dione 
9-Fluoro-11beta-hydroxypregna-4,16-diene-3,20-dione 
9-fluoro-17-methyl-5beta-androstane-3alpha,11beta,17beta-triol 
9-fluoro-2alpha-methylpregn-4-ene-3,11,20-trione 
9-Fluoroprednisolone 
9alpha-Fluoro-11beta,16alpha,17alpha,21-tetrahydroxypregn-4-ene-3,20-dione 
9alpha-Fluoro-11beta,17alpha,21-trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 
9alpha-hydroxy-3-oxo-23,24-bisnorchola-1,4-dien-22-oic acid 
9alpha-hydroxyandrosta-1,4-diene-3,17-dione 
A-norpregn-3(5)-ene-2,20-dione 
alclometasone 
alclometasone dipropionate  
aldosterone +   
aldosterone hemiacetal 
algestone +  
algestone acetonide 
algestone acetophenide 
amcinonide 
AMG-925 
andrographolide  
androsta-1,4,6-triene-3,17-dione 
arasertaconazole +   
beclomethasone +   
beclomethasone dipropionate 
benzocaine  
betamethasone +   
betamethasone acetate 
betamethasone acibutate 
betamethasone benzoate 
betamethasone dipropionate +   
betamethasone phosphate 
betamethasone valerate  
boldenone  
budesonide  
calotropone 
celastrol  
chloroethane +  
chloroprednisone 
chlorphenamine +   
clemastine +   
clemastine fumarate 
clionastatin A 
clionastatin B 
clobetasol +   
clobetasol propionate 
clocortolone +  
16alpha-Methylpregna-1,4-diene-3,20-dione bearing hydroxy substituents at the 11beta and 21 positions, fluorine at position 6 and chlorine at position 9. A medium potency corticosteroid, it is used as its 21-O-pivalate or caproate ester for the relief of inflammatory and pruritic (itching) skin disorders.
clocortolone pivalate 
cloprednol 
cortancyl 
cortexolone 
corticosterone +   
cortisol +   
cortisol 17-butyrate 
cortisol 17-valerate 
cortisol 21-sulfate 
cortisol phosphate 
cortisone +   
Cortol 
Cortolone 
crotamiton  
cyasterone 
cyproheptadine +   
cyproheptadine hydrochloride sesquihydrate 
cyproterone +   
cyproterone acetate  
danielone 
dapsone +   
Delta(1)-progesterone +   
demegestone 
deoxycortisol +   
desonide 
desoximetasone  
dexamethasone +   
dexamethasone phosphate  
dexamethasone valerate 
diflorasone +   
diflorasone diacetate 
diflucortolone 
dihydroxyacetone +   
dihydroxyacetone phosphate  
dioxygen +   
diphenhydramine +   
diphenhydramine hydrochloride 
doxorubicin +   
dydrogesterone  
E3040 +   
ebselen  
EET +   
emedastine +   
emedastine difumarate 
erythrulose +  
exemestane  
fluclorolone 
fluclorolone acetonide 
fludrocortisone +   
fludrocortisone acetate 
flumethasone +   
flumethasone pivalate 
flunisolide  
Fluocinolone 
fluocinolone acetonide  
fluocortolone 
fluorometholone +   
fluorometholone acetate 
fluoxymesterone  
fluperolone 
fluprednidene 
Flurandrenolide  
fluticasone +   
fluticasone furoate +  
fluticasone propionate 
friedelin +  
fruticoside A 
ginsenoside Rb1  
ginsenoside Rd +   
glycerone sulfate 
halometasone 
hydrocortamate +  
hydrocortisone caproate 
hydroxyacetone +  
hydroxypregnenolone +   
hydroxypyruvaldehyde 
hydroxyzine +   
impatienol 
lifitegrast 
loteprednol +   
loteprednol etabonate  
LSM-1835 
LSM-5687 
lupeol +   
medroxyprogesterone +   
medroxyprogesterone acetate  
megestrol +   
meprednisone  
methdilazine +   
methyl prednisolone-16-carboxylate +  
methyl prednisolone-16alpha-carboxylate 
methylprednisolone acetate 
minabeolide 1 
minabeolide 2 
minabeolide 4 
mometasone +   
mometasone furoate  
NCS172285 
nemorubicin  
non-steroidal anti-inflammatory drug +   
O-alkylglycerone +  
Osaterone acetate 
oxytetracycline  
palmitoyl ethanolamide  
Paramethasone 
paraminabeolide A 
paraminabeolide B 
paraminabeolide C 
paraminabeolide D 
paraminabeolide E 
pentanoic acid [11-hydroxy-17-(2-hydroxy-1-oxoethyl)-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] ester 
poststerone 
prednisolone +   
prednisolone phosphate 
prednisolone sodium phosphate 
prednisolone-16-carboxylic acid +  
prednisolone-16alpha-carboxylic acid +  
prednisone +   
prednival 
prednylidene  
pregn-5-ene-3,20-dione 
Pregna-4,11-diene-3,20-dione 
Pregna-4,16-diene-3,11,20-trione 
pregna-4,9(11)-diene-3,20-dione 
pregnan-21-ol 
pregnenolone +   
pregnenolone 3-beta-D-glucoside 
probucol  
progesterone +   
progesterone 3-O-(carboxymethyl)oxime +  
promegestone  
promethazine  
promethazine hydrochloride 
quercetin 3-O-beta-D-glucopyranoside  
rimexolone  
rizatriptan 
sertaconazole  
sertaconazole nitrate 
testolactone  
Tetrahydrocorticosterone 
tetrahydrocortisol 
thalidomide +   
tixocortol +  
triamcinolone +   
triamcinolone acetonide  
trimegestone  
ulipristal acetate 
Urocortisone 
VX-745  
withalongolide C 
withalongolide E 
zolmitriptan  

Synonyms
Exact Synonyms: 9-chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
Related Synonyms: 9-chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methyl-1,4-pregnadien-3,20-dione ;   9-chloro-6alpha-fluoro-16alpha-methyl-1,4-pregnadiene-11beta,21-diol-3,20-dione ;   Formula=C22H28ClFO4 ;   InChI=1S/C22H28ClFO4/c1-11-6-13-14-8-16(24)15-7-12(26)4-5-21(15,3)22(14,23)18(28)9-20(13,2)19(11)17(27)10-25/h4-5,7,11,13-14,16,18-19,25,28H,6,8-10H2,1-3H3/t11-,13+,14+,16+,18+,19-,20+,21+,22+/m1/s1 ;   InChIKey=YMTMADLUXIRMGX-RFPWEZLHSA-N ;   SMILES=[H][C@@]12C[C@@H](C)[C@H](C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(Cl)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C ;   clocortolona ;   clocortolonum
Xrefs: Beilstein:6318064 ;   CAS:4828-27-7 ;   DrugBank:DB00838 ;   KEGG:D07719 ;   Patent:DE2011559 ;   Patent:NL6412708 ;   Patent:US3729495 ;   Wikipedia:Clocortolone

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.