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Term:
Parent Terms Term With Siblings Child Terms
guanidines +     
spiroketal +     
(-)-dibromophakellin 
(2R)-2-carbamimidamido-2-cyclohexyl-N-(2-\{4-[3-(2,3-dichlorophenyl)-1H-pyrazol-5-yl]piperidin-1-yl\}-2-oxoethyl)acetamide 
(2R,3S,2'R)-nadolol +   
(2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-[4-(\{1-[(1E)-ethanimidoyl]piperidin-4-yl\}oxy)phenyl]propanoic acid 
(2S)-amino[(4R)-2-iminohexahydropyrimidin-4-yl]acetic acid 
(2S,3R)-capreomycidine 
(2S,4R)-1-acetyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(benzothiazol-2-ylcarbonyl)butyl]-4-hydroxypyrrolidine-2-carboxamide 
(3-Aminopropoxy)guanidine 
(3R,6R,8aS)-6-[(benzylsulfonyl)amino]-N-(3-carbamimidamidopropyl)-5-oxohexahydro-5H-[1,3]thiazolo[3,2-a]pyridine-3-carboxamide 
(3S)-3-hydroxy-L-arginine 
(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis[4-(hydroxymethyl)benzyl]-1,3-diazepan-2-ylidenecyanamide 
(6S,8aS)-2-(benzylsulfonyl)-N-\{[1-(N'-hydroxycarbamimidoyl)piperidin-4-yl]methyl\}-4-oxooctahydropyrrolo[1,2-a]pyrazine-6-carboxamide 
(N(omega)-L-arginino)succinic acid  
(R)-nicardipine +   
(S)-nicardipine +   
(S)-timolol (anhydrous) +   
(S)-timolol hemihydrate 
(S)-timolol maleate 
1,3-diphenylguanidine +   
1,4-diguanidinobutane 
1-(4-carboxy-2-guanidinophenyl)-5,5-bis(hydroxymethyl)pyrrolidin-2-one 
1-(4-tert-butylcarbamoylpiperazin-1-ylcarbonyl)-3-(3-guanidinopropyl)-4-oxoazetidine-2-carboxylic acid 
1-dodecylguanidine 
1-guanidino-1-deoxy-scyllo-inositol 
1-Methylguanidine hydrochloride 
11-beta-hydroxy-beta-saxitoxinol(2+) 
11-beta-hydroxysaxitoxin(2+) 
19-bromoaplysiatoxin 
1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol 
1D-3-amino-1-guanidino-1,3-dideoxy-scyllo-inositol 
2-(4-\{5-[(1H-benzimidazol-2-ylamino)methyl]thiophen-2-yl\}-1,3-thiazol-2-yl)guanidine 
2-(7-aminoheptyl)guanidine 
2-[2-(azocan-1-yl)ethyl]guanidine 
2-[5-(benzylamino)-2-(methylsulfanyl)-6-oxopyrimidin-1(6H)-yl]-N-[(1S)-4-carbamimidamido-1-(1,3-thiazol-2-ylcarbonyl)butyl]acetamide 
2-[5-amino-2-(3-methylphenyl)-6-oxopyrimidin-1(6H)-yl]-N-[(1S)-4-carbamimidamido-1-(1,3-thiazol-2-ylcarbonyl)butyl]acetamide 
2-[6-(methoxymethyl)-4-oxo-1H-pyrimidin-2-yl]-1-(4-methylphenyl)guanidine 
2-\{3-[(3S,8aS)-1,4-dioxooctahydropyrrolo[1,2-a]pyrazin-3-yl]propyl\}guanidine 
2-deoxystreptidine 
2-guanidinopropionic acid 
2-hydroxyoleic acid 
2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine 
2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine  
22,23-dihydroavermectin B1a +   
22,23-dihydroavermectin B1b +   
26-desglucoavenacoside A 
26-desglucoavenacoside B 
3''-adenylylstreptomycin 
3,5-diamino-N-[amino-[(2,4-dichlorophenyl)methylimino]methyl]-6-chloro-2-pyrazinecarboxamide 
3,5-diamino-N-[amino-[(3,4-dichlorophenyl)methylimino]methyl]-6-chloro-2-pyrazinecarboxamide 
3-guanidinopropanoic acid  
3-methylarginine 
4-[(E)-\{amino[(3-methylbut-2-en-1-yl)amino]methylidene\}amino]butanoic acid 
4-\{[(E)-amino(imino)methyl]amino\}-N-(\{(2S)-1-[N-(2-naphthylsulfonyl)-L-seryl]pyrrolidin-2-yl\}methyl)butanamide 
4-Guanidino-1-butanol 
4-guanidinobenzoic acid +   
4-guanidinobutanamide 
4-guanidinobutanoic acid 
4-guanidinobutyric acid +  
4-hydroxy-3-methoxycinnamoylagmatine +  
4-hydroxychalcone  
5-(N,N-hexamethylene)amiloride  
5-(N-methyl-N-propyl)amiloride 
5-guanidinohydantoin 
6-[4-amino-4-hydroxy-2-oxo-3,4-dihydropyrimidin-1(2H)-yl]-3-[3-amino-5-(N-methylguanidino)pentanoylamino]-3,6-dihydro-2H-pyran-2-carboxylic acid 
6-guanidinohexanoic acid 
6-O-galloyl-beta-D-glucose 
9-(2-\{[amino(iminio)methyl]amino\}ethoxy)-3-(2-deoxy-5-O-phosphono-beta-D-ribofuranosyl)-3H-pyrimido[5,4-b][1,4]benzoxazin-2(10H)-one 
[N-(4-cyanophenyl)-N'-(diphenylmethyl)guanidine]acetic acid  
\{3-[(1,3,2-dioxaborolan-2-yl)oxy]propyl\}guanidine 
abafungin 
Ac-(D)Phe-Pro-boroArg-OH 
acebutolol  
acebutolol hydrochloride 
acetylagmatine 
acetylblasticidin S 
ACT-132577 +   
aculeatol E 
agmatine +   
ajmalicine  
alfuzosin +   
aliskiren +   
aliskiren fumarate 
alpha-adrenergic antagonist +   
alpha-allenylagmatine 
alpha-methyl-L-dopa +   
alpha-methyl-L-dopa ethyl ester 
alpha-methyl-L-tyrosine 
alpha-N-substituted L-arginine +   
alprenolol +   
amcinonide 
amidinoproclavaminic acid 
amiloride +   
aminoguanidine +   
aminopotentidine 
amlodipine +   
amlodipine benzenesulfonate +  
angiotensin (1-9) 
angiotensin (1-9) dizwitterion 
apelin-13 
aplysiatoxin 
apraclonidine +  
argatroban  
arginine +   
atenolol +   
auraptene  
avenacoside A +  
avenacoside B +  
Avermectin B2a aglycone 
azilsartan +   
azilsartan kamedoxomil 
azilsartan medoxomil 
BAR0329 
batzelladine A 
batzelladine B 
BAY 41-2272 
bendroflumethiazide +   
Benzamil  
benzoylagmatine 
benzthiazide 
bepridil +   
beraprost  
beraprost sodium 
beta-adrenergic antagonist +   
beta-guanidino-L-alanine 
beta-guinidoxypropionamide 
beta-saxitoxinol(2+) 
betaxolol +   
betaxolol hydrochloride +  
bethanidine +  
bethanidine sulfate 
betrixaban 
bevantolol +   
bevantolol hydrochloride +  
biguanide +   
biguanides +   
bimatoprost 
bisoprolol +   
bopindolol  
bosentan +   
bretylium +   
bretylium tosylate  
brimonidine +   
bupivacaine  
bupivacaine hydrochloride (anhydrous) +  
bupivacaine hydrochloride hydrate 
Byvalson 
Bz-Arg-OEt 
callipeltin A 
camostat  
camostat mesylate 
candesartan  
captopril +   
carmoxirole  
carmoxirole hydrochloride 
carteolol  
carteolol hydrochloride 
carvedilol  
cassaine 
Chlorhexidine hydrochloride 
chlorothiazide 
chrysopine +  
cilazapril +   
cilazapril monohydrate  
cilnidipine  
cimetidine +   
cinaciguat  
cleistanthin A 
cleistanthin B +  
clonidine +   
clozapine  
colforsin daropate 
colforsin daropate hydrochloride  
corilagin  
crambescidin 401 
crambescidin 800 
crambescidin 826 
creatine +   
cyanoguanidine 
cyclothiazide  
cylindrospermopsins +   
Cypridina luciferin +  
D-nopaline 
D-octopine 
debrisoquin +   
debromoaplysiatoxin 
decarbamoylsaxitoxin 
deoxyamidinoproclavaminic acid 
diazoxide  
dihydroergocristine +  
diltiazem  
diltiazem hydrochloride 
dioscin  
diosgenin +   
diosgenin 3-O-beta-D-glucoside 
dorzolamide +   
dorzolamide hydrochloride  
doxazosin +   
droxidopa 
E64 
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor +   
efonidipine 
enalapril +   
enalapril maleate 
enalaprilat (anhydrous) +   
enalaprilat dihydrate  
enrasentan  
epinastine +   
eplerenone  
eprinomectin component B1a +   
eprinomectin component B1b +   
eprosartan +   
eprosartan methanesulfonate 
ethylisopropylamiloride  
famotidine +   
fasudil  
fasudil hydrochloride +  
fasudil hydrochloride hydrate 
felodipine  
fenoldopam  
fluprostenol +   
forasartan 
forskolin +   
fosinopril  
fosinopril sodium 
fosinoprilat +   
gabexate methanesulfonate  
Galegine 
gamma-hydroxyarginine +  
grayanotoxin I 
GSK2181236A  
guanadrel 
A spiroketal resulting from the formal condensation of the keto group of cyclohexanone with the hydroxy groups of 1-(2,3-dihydroxypropyl)guanidine. A postganglionic adrenergic blocking agent formerly used (generally as the sulfate salt) for the management of hypertension, it has been largely superseded by other drugs less likely to cause orthostatic hypotension (dizzy spells on standing up or stretching).
guanadrel sulfate 
guanazodine 
guancidine 
guanethidine +   
guanethidine monosulfate +  
guanethidine sulfate 
guanidine +   
guanidinoethyl methyl phosphates +  
Herdmanine A 
Herdmanine B 
hexamidine 
hordatine A 
hordatine B 
HU-308  
hydralazine +   
hydralazine hydrochloride 
hydramethylnon +   
hydrochlorothiazide  
hydroflumethiazide 
hypotaurocyamine +  
imidapril +   
imidaprilat  
iminoarginine 
iminoctadine +  
indanomycin 
indapamide  
irbesartan  
isoamyl nitrite 
isopropyl unoprostone 
kaempferide +   
ketanserin  
ketanserin tartrate 
L-803087 
L-arginine amide 
L-arginine hydroxamate 
labetalol  
latanoprost  
latanoprost free acid +   
levobupivacaine +   
levobupivacaine hydrochloride (anhydrous) +  
levobupivacaine hydrochloride hydrate +  
lisinopril dihydrate  
lofexidine 
lombricine +  
losartan +   
lurasidone 
lurasidone hydrochloride  
macitentan  
massadine 
metformin  
methylguanidine +  
metipranolol  
metipranolol hydrochloride 
metolazone  
metoprolol  
milbemycin +   
minoxidil  
mitoguazone 
monensin A  
morin  
mutalomycin 
N(1)-aminoaminopropylagmatine 
N(2)-(2-carboxyethyl)-L-arginine 
N(2)-\{[(1R)-1-(4-bromophenyl)ethyl]carbamoyl\}-L-asparaginyl-N-\{(1S)-4-carbamimidamido-1-[(S)-(2S)-2,3-dihydro-1,3-thiazol-2-yl(hydroxy)methyl]butyl\}-L-valinamide 
N(2)-carbamimidoyl-N-\{2-[4-(3-\{4-[(5-carboxyfuran-2-yl)methoxy]-2,3-dichlorophenyl\}-1-methyl-1H-pyrazol-5-yl)piperidin-1-yl]-2-oxoethyl\}-D-leucinamide 
N(5)-methyl-L-arginine 
N(gamma)-nitro-L-arginine 
N(omega),N'(omega)-dimethyl-L-arginine +  
N(omega),N(omega)-dimethyl-L-arginine +   
N(omega)-methyl-L-arginine  
N(omega)-methyl-L-arginine zwitterion 
N,N'-(p-xylylidene)bis(aminoguanidine) +  
N-(2-\{4-[3-(4-\{[4-(acetylamino)benzyl]oxy\}-2,3-dichlorophenyl)-1-methyl-1H-pyrazol-5-yl]piperidin-1-yl\}-2-oxoethyl)-N(2)-carbamimidoyl-D-leucinamide 
N-[(1R)-2-\{(2S)-2-[(3-carbamimidamidopropyl)carbamoyl]piperidin-1-yl\}-1-(cyclohexylmethyl)-2-oxoethyl]glycine 
N-[(1S)-1-(1,3-benzothiazol-2-ylcarbonyl)-4-carbamimidamidobutyl]cyclopentanecarboxamide 
N-[(1S)-1-\{[(1S)-4-[(diaminomethyl)amino]-1-(1,3-thiazol-2-ylcarbonyl)butyl]carbamoyl\}-2-methylpropyl]-4-methylpentanamide 
N-[(1S)-1-\{[(1S)-4-carbamimidamido-1-(1,3-thiazol-2-ylcarbonyl)butyl]carbamoyl\}-2-methylpropyl]-2-(3-chlorophenyl)-2-oxoacetamide 
N-[(1S)-4-carbamimidamido-1-(1,3-thiazol-2-ylcarbonyl)butyl]-2-[2-(3,4-dichlorophenyl)-5-[(1-methylethyl)amino]-6-oxopyrimidin-1(6H)-yl]acetamide 
N-[(1S)-4-carbamimidamido-1-(1,3-thiazol-2-ylcarbonyl)butyl]-2-[2-(3-methylphenyl)-6-oxo-5-[(quinolin-8-ylmethyl)amino]pyrimidin-1(6H)-yl]acetamide 
N-\{(1S)-4-carbamimidamido-1-[(S)-hydroxy(1,3-thiazol-2-yl)methyl]butyl\}-N(2)-carbamoyl-L-valinamide 
N-\{[(2S)-1-(N-\{[cis-4-(carbamimidamidomethyl)cyclohexyl]carbonyl\}-3-cyclohexyl-D-alanyl)azetidin-2-yl]carbonyl\}-D-tyrosyl-N(6)-carbamimidoyl-L-lysinamide 
N-acyl-L-arginine +  
N-amidino-L-aspartate(2-) 
N-amidino-L-glutamic acid 
N-amidinoaspartic acid +  
N-carbamimidoylpiperidine +  
N-guanylhistamine 
N-hydroxydebrisoquine O-glucuronide 
N-hydroxyguanidine 
N6-Methylagmatine 
nadolol  
nafamostat  
nafamostat methanesulfonate 
nebivolol  
nebivolol hydrochloride +  
nelociguat 
neosaxitoxin  
nerolidol +   
nicardipine  
nimodipine  
nisoldipine  
nitensidine E 
nitrendipine  
nitroguanidine derivative +   
nitroguanidine insecticide 
NK154183A 
NK154183B 
nocamycin E +  
nocamycin I 
nolinospiroside F 
norverapamil  
oleuropein +   
oligomycin +   
olmesartan  
ossamycin 
oxidized Cypridina luciferin 
p-coumaroylagmatine +  
palmitoyl ethanolamide  
papulacandin +  
paralytic shellfish toxin +   
Pectenotoxin 1 
Pectenotoxin 2 
Pectenotoxin 7 
pentamethonium +  
pentamethonium bromide 
pentolinium tartrate  
peramivir 
periciazine  
perindopril  
perindopril arginine +  
perindopril erbumine 
perindoprilat 
phaseolotoxin 
phenyl biguanide  
Phenylamil  
phleomycin D1 +  
pindolol +   
polyhexamethylene biguanide 
praliciguat 
pratosartan 
prazosin +   
Prestalia 
profenamine +   
profenamine hydrochloride 
propamidine 
Propanoylagmatine 
propranolol +   
quetiapine +   
quinapril 
quinapril hydrochloride  
quinaprilat  
quinethazone 
remikiren 
rescinnamine  
reserpine  
riociguat  
rottlerin  
Salinomycin  
saxitoxin +   
scoparone  
SLM6071469 
sodium nitrite  
spirapril  
spiraprilat +   
spironolactone  
spiroxamine  
streptidine +   
streptothricin +  
streptothricin acid +  
synthalin A 
TAMe 
taurocyamine +  
tegaserod +   
telmisartan  
terazosin +   
tienilic acid  
tigogenin 3-O-beta-D-glucopyranoside 
TNP-ATP  
tolazoline  
torasemide +   
trandolapril  
trandolaprilat +   
travoprost 
trazodone +   
trazodone hydrochloride 
treprostinil +   
trichlormethiazide  
trimethaphan +   
trimethaphan camsylate 
unoprostone +  
valsartan +   
vanchrobactin 
verapamil  
vericiguat 
vincamine  
visnagin 
WF14865A 
WF14865B 
zanamivir 
zarzissine 
zolasartan 

Synonyms
Exact Synonyms: 1-(1,4-dioxaspiro[4.5]dec-2-ylmethyl)guanidine
Related Synonyms: Formula=C10H19N3O2 ;   InChI=1S/C10H19N3O2/c11-9(12)13-6-8-7-14-10(15-8)4-2-1-3-5-10/h8H,1-7H2,(H4,11,12,13) ;   InChIKey=HPBNRIOWIXYZFK-UHFFFAOYSA-N ;   SMILES=NC(=N)NCC1COC2(CCCCC2)O1 ;   guanadrelum
Xrefs: Beilstein:8325419 ;   CAS:40580-59-4 ;   DrugBank:DB00226 ;   Drug_Central:1339 ;   HMDB:HMDB0014371 ;   KEGG:C07035 ;   KEGG:D08029 ;   PMID:3896742 ;   PMID:6621504 ;   PMID:7206175 ;   Patent:US3547951 ;   Reaxys:8325419 ;   Wikipedia:Guanadrel
Cyclic Relationships: is_conjugate_base_of CHEBI:72602

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