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Term:
topoisomerase IV inhibitor (CHEBI:53559)
Annotations: Rat: (555) Mouse: (553) Human: (553) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
2,2,3,3-tetrahydroxy-2,3-dihydronaphthalene-1,4-dione 
actinodaphnine 
EC 5.99.1.2 (DNA topoisomerase) inhibitor +   
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor +   
topoisomerase IV inhibitor +   
A topoisomerase inhibitor that inhibits DNA topoisomerase IV, which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.

Synonyms
Related Synonyms: topoisomerase IV inhibitors

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.