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Term:
2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine (CHEBI:52450)
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Parent Terms Term With Siblings Child Terms
(+)-(12E,2S,3S,4R,5R,6R,9S,11S,15R)-3-benzoyloxy-5,6-epoxylathyr-12-en-15-ol-14-one 
(+-)-menthol 
(-)-(12E,2S,3S,4R,5R,6R,9S,11S,15R)-3-acetoxy-15-benzoyloxy-5,6-epoxylathyr-12-en-14-one 
(-)-(5E,12E,2S,3S,4S,9S,11S,15R)-15-benzoyloxylathyra-5,12-dien-3-ol-14-one 
(-)-(6Z,12E,2S,3S,4R,5R,9S,11S,15R)-3-acetoxy-15-benzoyloxylathyra-6,12-dien-5-ol-14-one 
(-)-(6Z,12E,2S,3S,4R,5R,9S,11S,15R)-5-acetoxy-15-benzoyloxylathyra-6,12-dien-3-ol-14-one 
(2R,3S,2'R)-nadolol +   
(E)-cinnamaldehyde +   
(R)-adrenaline +   
(S)-timolol (anhydrous) +   
(S)-timolol hemihydrate 
(S)-timolol maleate 
1,3-dinitroglycerol +  
1-[(9Z)-hexadecenyl]-2-acetyl-sn-glycero-3-phosphocholine 
1-decyl-2-acetyl-sn-glycero-3-phosphocholine 
1-dodecyl-2-acetyl-sn-glycero-3-phosphocholine 
1-tetradecyl-2-acetyl-sn-glycero-3-phosphocholine 
15beta-O-benzoyl-5alpha-hydroxyisolathyrol 
2-hydroxyoleic acid 
2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine 
2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine  
A 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine betaine which has octadecyl as the alkyl group. PAF is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis.
3-pyridinemethanol  
4-hydroxychalcone  
5beta-dihydrotestosterone 
6-aminohexanoic acid +   
6-O-galloyl-beta-D-glucose 
7-epiclusianone 
8-epi-prostaglandin E2  
8-epi-prostaglandin F2alpha +   
acebutolol  
acebutolol hydrochloride 
acetylcholine +   
ACT-132577 +   
ACT-333679 +  
adenosine +   
ajmalicine  
alfuzosin +   
alginic acid  
aliskiren +   
aliskiren fumarate 
alpha-methyl-L-dopa +   
alpha-methyl-L-dopa ethyl ester 
alpha-methyl-L-tyrosine 
alprenolol +   
amlodipine +   
amlodipine benzenesulfonate +  
anandamide +   
angiotensin (1-9) 
angiotensin (1-9) dizwitterion 
anticoagulant +   
apelin-13 
Arg-Phe 
argipressin  
asenapine 
asenapine maleate 
atenolol +   
auraptene  
avanafil 
azilsartan +   
azilsartan kamedoxomil 
azilsartan medoxomil 
bamethan +  
BAY 41-2272 
bendroflumethiazide +   
benzthiazide 
benzyl nicotinate 
bepridil +   
betahistine  
betaxolol +   
betaxolol hydrochloride +  
bethanidine +  
bethanidine sulfate 
bevantolol +   
bevantolol hydrochloride +  
bimatoprost 
bisoprolol +   
bopindolol  
bosentan +   
bradykinin +  
bretylium +   
bretylium tosylate  
brimonidine +   
bucladesine  
Byvalson 
candesartan  
captopril +   
carbon dioxide  
carbon monoxide  
carmoxirole  
carmoxirole hydrochloride 
carpronium chloride 
carteolol  
carteolol hydrochloride 
carvedilol  
cassaine 
CGP 12177  
CGP-42112A  
chlorothiazide 
cilazapril +   
cilazapril monohydrate  
cilnidipine  
cilostazol  
cinaciguat  
cleistanthin A 
cleistanthin B +  
clonidine +   
clonixin 
clonixin lysine salt 
convallatoxin 
corilagin  
cyclandelate 
cyclothiazide  
debrisoquin +   
dermatan sulfate  
devapamil 
diallyl trisulfide  
diazoxide  
dihydroergocristine +  
dihydroergocristine mesylate +  
diltiazem  
diltiazem hydrochloride 
diltiazem(1+) +  
dinitrogen oxide  
dipyridamole  
dorzolamide +   
dorzolamide hydrochloride  
dotarizine 
doxazosin +   
droxidopa 
dyphylline +  
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor +   
efonidipine 
enalapril +   
enalapril maleate 
enalaprilat (anhydrous) +   
enalaprilat dihydrate  
enrasentan  
eplerenone  
eprosartan +   
eprosartan methanesulfonate 
ergoloid mesylate 
erythrityl tetranitrate 
esatenolol 
esmolol +   
esmolol hydrochloride 
eupatorin  
felodipine  
fenoldopam  
fluprostenol +   
forasartan 
forskolin +   
fosinopril  
fosinopril sodium 
fosinoprilat +   
graminone B 
grayanotoxin I 
GSK2181236A  
guanadrel 
guanadrel sulfate 
guanethidine +   
guanethidine monosulfate +  
guanethidine sulfate 
HU-308  
hydralazine +   
hydralazine hydrochloride 
hydrochlorothiazide  
hydroflumethiazide 
hydrogen sulfide +   
icatibant +   
icatibant acetate 
ICI 118551  
Ile(5)-angiotensin II (1-7) 
iloprost  
imidapril +   
imidaprilat  
indanomycin 
indapamide  
iodocyanopindolol  
irbesartan  
isoamyl nitrite 
isopropyl unoprostone 
isosorbide dinitrate  
isosorbide mononitrate  
JWH-133 
kaempferide +   
ketanserin  
khellin 
labetalol  
latanoprost  
latanoprost free acid +   
leukotriene C4 +   
leukotriene D4  
levobunolol +   
levobunolol hydrochloride 
levosimendan 
lificiguat 
lisinopril dihydrate  
lofexidine 
losartan +   
macitentan  
methacholine +   
methyl brevifolincarboxylate 
metipranolol  
metipranolol hydrochloride 
metolazone  
metoprolol  
milrinone  
minoxidil  
morin  
morphine +   
N-arachidonoyl-L-serine 
N-ethyl-5'-carboxamidoadenosine  
n-pentyl nitrite 
nadolol  
nebivolol  
nebivolol hydrochloride +  
nelociguat 
nicorandil  
nicotinic acid +   
nifedipine  
nimodipine  
nisoldipine  
nitrendipine  
nitric oxide  
nitroflurbiprofen  
nitroglycerin  
norverapamil  
oleuropein +   
olmesartan  
oxytocin  
palmitoyl ethanolamide  
papaverine  
partial prostacyclin agonist +  
penbutolol sulfate 
pentaerythritol tetranitrate  
pentolinium tartrate  
perindopril  
perindopril arginine +  
perindopril erbumine 
perindoprilat 
petasin 
phentolamine  
pimobendan  
pindolol +   
pinocembrin +   
platelet aggregation inhibitor +   
poly(vinylpyrrolidone) +   
PP2 
practolol  
praliciguat 
pratosartan 
prazosin +   
Prestalia 
propranolol +   
prostaglandin E1 +   
quinapril 
quinapril hydrochloride  
quinaprilat  
quinethazone 
rescinnamine  
reserpine  
riociguat  
rottlerin  
S-nitroso-L-cysteine +   
S-nitroso-N-acetyl-D-penicillamine  
selexipag 
sildenafil +   
sildenafil citrate  
sodium alginate 
sodium nitrite  
sodium nitroprusside +  
sodium nitroprusside dihydrate 
sotalol  
sotalol hydrochloride 
spathulenol  
sphingosine 1-phosphate  
spirapril  
spiraprilat +   
spironolactone  
tadalafil  
telmisartan  
terazosin +   
tetramethylpyrazine  
theobromine  
theophylline +   
ticlopidine +   
tienilic acid  
tolazoline  
torasemide +   
trandolapril  
trandolaprilat 
tranexamic acid  
travoprost 
treprostinil +   
triacsin C  
trichlormethiazide  
trimethaphan +   
trimethaphan camsylate 
troglitazone  
unoprostone +  
valsartan +   
vardenafil 
verapamil  
vericiguat 
vincamine  
visnagin 
zofenopril 
zofenopril calcium 
zofenoprilat 
zofenoprilat arginine 
zolasartan 

Synonyms
Exact Synonyms: (2R)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate ;   (2RR)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate
Related Synonyms: (-)-1-O-octadeyl-2-O-acetyl-sn-glycerylphosphocholine ;   (R)-7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptaconasan-1-aminium hydroxide inner salt 4-oxide ;   1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine ;   1-O-Octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine ;   1-O-Octadecyl-platelet-activating factor ;   1-O-Stearoyl-2-acetyl-sn-glyceryl-3-phosphorylcholine ;   1-O-Stearyl-2-acetyl-sn-glyceryl-3-phosphorylcholine ;   1-O-octadecyl 2-O-acetyl sn-glycero-3-phosphorylcholine ;   1-O-octadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine ;   1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine ;   1-O-octadecyl-PAF ;   1-octadecyl-2-acetyl-sn-glycero-3-phosphocholine ;   AGEPC ;   Blood platelet activating factor-aether ;   Blood platelet-activating factor ;   C18-PAF-acether ;   C18-Paf ;   C18:0 PAF ;   Formula=C28H58NO7P ;   InChI=1S/C28H58NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-33-25-28(36-27(2)30)26-35-37(31,32)34-24-22-29(3,4)5/h28H,6-26H2,1-5H3/t28-/m1/s1 ;   InChIKey=ZXCIEWBDUAPBJF-MUUNZHRXSA-N ;   PAF ;   PAF-acether ;   PC(O-18:0/2:0) ;   Ro 14-8161 ;   SMILES=P(OC[C@@H](COCCCCCCCCCCCCCCCCCC)OC(C)=O)(=O)(OCC[N+](C)(C)C)[O-] ;   acetyl-glyceryl-ether-phosphorylcholine ;   blood platelet activating factor-acether ;   phosphatidylcholine (O-18:0/2:0) ;   platelet activating factor ;   platelet activating factor-acether
Alternate IDs: CHEBI:26164 ;   CHEBI:52390 ;   CHEBI:75217
Xrefs: Beilstein:5364572 ;   CAS:74389-69-8 ;   DrugBank:DB02261 ;   LIPID_MAPS_instance:LMGP01020094 ;   Reaxys:5364572 ;   Wikipedia:Platelet-activating_factor

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.