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Term:
EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor (CHEBI:50781)
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Parent Terms Term With Siblings Child Terms
EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor +   
An EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of of 3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)), EC 1.3.1.22, the enzyme which converts testosterone (CHEBI:17347) into the more potent androgen 5alpha-dihydrotestosterone.
EC 1.3.1.43 (arogenate dehydrogenase) inhibitor +   
EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitor +   
EC 1.3.1.72 (Delta(24)-sterol reductase) inhibitor +  
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor +   
EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor +   

Synonyms
Related Synonyms: 3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) inhibitor ;   3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+)) inhibitors ;   3-oxo-5alpha-steroid 4-dehydrogenase inhibitor ;   3-oxo-5alpha-steroid 4-dehydrogenase inhibitors ;   3-oxo-5alpha-steroid:NADP+ Delta(4)-oxidoreductase inhibitor ;   3-oxo-5alpha-steroid:NADP+ Delta(4)-oxidoreductase inhibitors ;   3-oxosteroid 5alpha-reductase inhibitor ;   3-oxosteroid Delta4-dehydrogenase inhibitor ;   4-ene-3-oxosteroid 5alpha-reductase inhibitor ;   4-ene-5alpha-reductase inhibitor ;   5alpha-oxidoreductase inhibitor ;   5alpha-oxidoreductase inhibitors ;   5alpha-reductase inhibitor ;   5alpha-reductase inhibitors ;   Delta(4)-3-ketosteroid 5alpha-oxidoreductase inhibitor ;   Delta(4)-3-ketosteroid 5alpha-oxidoreductase inhibitors ;   EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitors ;   EC 1.3.1.22 inhibitor ;   EC 1.3.1.22 inhibitors ;   cholest-4-en-3-one 5alpha-reductase inhibitor ;   cholestenone 5alpha-reductase inhibitor ;   cholestenone 5alpha-reductase inhibitors ;   reduced nicotinamide adenine dinucleotide phosphate:Delta(4)-3-ketosteroid 5alpha-oxidoreductase inhibitor ;   reduced nicotinamide adenine dinucleotide phosphate:Delta(4)-3-ketosteroid 5alpha-oxidoreductase inhibitors ;   steroid 5alpha-hydrogenase inhibitor ;   steroid 5alpha-hydrogenase inhibitors ;   steroid 5alpha-reductase inhibitor ;   steroid 5alpha-reductase inhibitors ;   testosterone 5alpha-reductase inhibitor ;   testosterone 5alpha-reductase inhibitors ;   testosterone Delta(4)-5alpha-reductase inhibitor ;   testosterone Delta(4)-5alpha-reductase inhibitors ;   testosterone Delta(4)-hydrogenase inhibitor ;   testosterone Delta(4)-hydrogenase inhibitors
Xrefs: Wikipedia:5-alpha-reductase_inhibitor

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.