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Ontology Browser

Parent Terms Term With Siblings Child Terms
GABA agent +     
calcium channel modulator +   
CFTR potentiator +   
fenamic acid  
GABA agonist +   
GABA antagonist +   
GABA modulator +   
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
GABA-gated chloride channel antagonist +   
ion transport inhibitor +   
ionophore +   
neurotransmitter transporter modulator +   
potassium channel modulator +   
sodium channel modulator +   
TRP channel blocker +   
TRP channel modulator +   
valproate semisodium 
valproic acid +   

Related Synonyms: GABA modulators

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