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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
dicarboximide +     
pyrrolidinone +     
(+)-catechin monohydrate 
(-)-epigallocatechin 3-gallate +   
(-)-selegiline  
(3-amino-2,5-dioxopyrrolidin-1-yl)acetic acid 
(3S)-tetrahydrofuran-3-yl (1R,2S)-3-[4-((1R)-2-\{[(S)-amino(hydroxy)methyl]oxy\}-2,3-dihydro-1H-inden-1-yl)-2-benzyl-3-oxopyrrolidin-2-yl]-1-benzyl-2-hydroxypropylcarbamate 
(4R)-2-(4-bromo-2-fluorobenzyl)-6-fluoro-1H,2'H,5'H-spiro[isoquinoline-4,3'-pyrrolidine]-1,2',3,5'(2H)-tetrone 
(aminooxy)acetic acid  
(E)-10-hydroxydec-2-enoic acid +   
(R)-efonidipine +  
(R)-nicardipine +   
(R)-oxybutynin +   
(R)-pantothenic acid +   
(R)-rosmarinic acid 
(R,R)-5,11-diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol 
(S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propionic acid 
(S)-4,4'-(1-methylethane-1,2-diyl)bis(piperazine-2,6-dione) 
(S)-efonidipine +  
(S)-malic acid +  
(S)-nicardipine +   
1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose  
1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine hydrochloride 
17alpha-estradiol +   
17beta-estradiol +   
1D-chiro-inositol +  
2,4-dinitrophenol +   
2,5-dihydroxycinnamic acid methyl ester  
2,6-di-tert-butyl-4-methylphenol  
2-(1,3-benzothiazol-2-yl)phenol 
2-(1,3-benzoxazol-2-yl)phenol 
2-(1H-benzimidazol-2-yl)aniline 
2-(2-amino-3-methoxyphenyl)chromen-4-one 
2-(4-hydroxyphenyl)ethanol +   
2-[5-(but-3-yn-2-yloxy)-4-chloro-2-fluorophenyl]-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione +  
2-amino-2-deoxy-D-glucopyranose +   
2-aminoethoxydiphenylborane  
2-deoxy-D-glucose +   
2-oxoglutarate(2-) 
3'-Demethoxypiplartine 
3,3-diethyl-2-pyrrolidinone 
3,4-dichloroisocoumarin 
3-(11,11-dimethyl-8-methylene-4-oxo-5-bicyclo[7.2.0]undecanyl)oxolane-2,5-dione 
3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione +   
3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol 
4'-O-methyl-(-)-epicatechin 
4,5-dianilinophthalimide  
4-(5-amino-1,2,4-oxadiazol-3-yl)-1,2,5-oxadiazol-3-amine 
4-[4-(2,5-dioxopyrrolidin-1-yl)phenylamino]-4-hydroxybutyric acid 
4-[5-(4-methyl-1,2,5-oxadiazol-3-yl)-1H-1,2,4-triazol-3-yl]-1,2,5-oxadiazol-3-amine 
4-amino-1,8-naphthalimide +   
4-Maleimido-TEMPO 
4-phenyl-3-furoxancarbonitrile  
5,7-dihydroxy-4'-methoxyflavone +   
5-(2,2-diferuloylethen-1-yl)thalidomide 
5-[2-(feruloyl)ethen-1-yl]thalidomide 
5-chlorospiro[indole-3,2'-[1,3]oxathiolan]-2(1H)-one 
5alpha-dihydrodeoxycorticosterone 
6,7-dimethyl-2-phenylquinoxaline 
7-(diethylamino)-N-[(Z)-2-(2,5-dioxopyrrolidin-1-yl)vinyl]-2-oxo-2H-chromene-3-carboxamide 
7-amino-2-(ethylsulfanyl)-5-oxo-1-phenyl-1,5-dihydro[1,2,4]triazolo[1,5-a]pyridine-6,8-dicarbonitrile 
\{[(1r,7r)-4-(4-acetamidophenyl)-3,5-dioxo-4-azatricyclo[5.2.2.0(2,6)]undec-1-yl]carbamoyloxy\}acetic acid 
acarbose +   
acetazolamide +   
acetylsalicylic acid +   
adinazolam  
Alexa Fluor 350 
Alexa Fluor 430 
Alexa Fluor 430(1-) +  
alpha,alpha-trehalose +   
alpha-asarone 
alprazolam  
aminoglutethimide +   
amlodipine +   
amlodipine benzenesulfonate +  
AMN082 dihydrochloride 
amoxapine  
amperozide  
amperozide hydrochloride 
androsterone +   
anthra[1,9-cd]pyrazol-6(2H)-one  
asperparaline A 
ATTO 425-3 
ATTO 465-3 
ATTO 465-4 
ATTO 495-3 
ATTO 495-4 
ATTO 520-3 
ATTO 520-4 
ATTO 610-3 
ATTO 610-4 
ATTO 635-3 
ATTO 635-4 
bacitracin  
baicalein +   
barbinine 
beauveriolide I 
bepridil +   
berberine  
beta-maltose +   
bevantolol +   
bevantolol hydrochloride +  
bezafibrate  
Blue pigment 
BODIPY 630/650-X 
BODIPY 650/665-X 
BODIPY FL-X 
BODIPY TMR-X 
BODIPY TR-X 
brivaracetam 
BRL-50481 
buformin 
butein  
C60 fullerene  
caffeine +   
calciol +   
carbamazepine +   
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  
carnosine +   
cascade yellow 
CCCP  
celecoxib  
CGP 78608 
CGP 78608 hydrochloride 
chicoric acid  
chloramphenicol +   
chlorprothixene hydrochloride 
Chrome fast yellow 8GL (acid form) 
ciclopirox olamine 
cilnidipine  
cinnarizine  
cinolazepam 
cis-flupenthixol dihydrochloride 
cladoniamide A 
cladoniamide B 
cladoniamide C 
clobazam  
clofibrate  
clonazepam  
clorazepic acid 
cobalt dichloride +   
creatine +   
cromoglycic acid 
curcumin +   
cycloheximide  
cyclopiazonic acid +   
cyclosporin A +   
cyproterone acetate  
cysteamine +   
D-pinitol 
dabcyl SE dye 
dafadine A 
danazol  
demeclocycline +   
devapamil 
diacetylspermidine 
diazaborine +  
diazepam +   
dibromoacetic acid  
dicarboximide antifungal agent +   
dichloroacetate 
didanosine  
didesethylflurazepam 
diethylstilbestrol +   
dihydroergocristine mesylate +  
diltiazem  
diltiazem hydrochloride 
diltiazem(1+) +  
dimethyl sulfoxide +   
dipotassium clorazepate 
dizocilpine  
dizocilpine maleate  
dotarizine 
doxazosin mesylate 
doxycycline +   
doxycycline HCl +  
EDTA monocalcium diisodium salt 
efonidipine 
elatine 
eliprodil  
ellagic acid +   
enalapril +   
eslicarbazepine acetate 
esoxybutynin +   
estazolam  
ethidium bromide 
ethosuximide +   
A dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.
ethotoin +   
ethoxyquin  
ethyl 3-(3,5-dichlorophenyl)-5-methyl-2,4-dioxo-1,3-oxazolidine-5-carboxylate +   
ethylenediaminetetraacetic acid  
EUK-134  
EUK-8 
eupatorin  
everolimus  
ezogabine  
fasudil  
fasudil hydrochloride +  
fasudil hydrochloride hydrate 
felbamate  
felodipine  
fenofibrate  
ferulsinaic acid 
fisetin +   
flumioxazin 
flurazepam +   
Formothion 
fumaric acid +   
gabapentin +   
gabapentin enacarbil 
gallic acid +   
gamma-decalactone  
genistein +   
glaucarubinone 
glutathione +   
glutaurine 
glutaurine zwitterion 
glutaurine(1-) 
glycerol +   
GSK-5498A 
Guanabenz acetate 
Guanfacine hydrochloride 
hentriacontan-16-one 
hispidulin  
ibuprofen +   
indigoidine 
isoliquiritigenin +   
IWR-1-endo 
IWR-1-exo 
juglone  
kaempferol +   
kanamycin A sulfate 
kenpaullone  
keto-D-fructose 1,6-bisphosphate  
kinetin +  
KN-93  
L-3-aminosuccinimide 
L-ascorbic acid +   
L-cycloserine +  
L-glutamimide 
L-lysine +   
L-methionine sulfoximine +  
L-thioproline +  
lamotrigine  
lanperisone 
lanperisone hydrochloride 
latrepirdine 
lenalidomide  
levetiracetam  
licarbazepine +  
lipoic acid +   
lissamine flavine FF free acid 
lithium chloride  
lithocholic acid +   
lonidamine +   
Loratadine  
loxapine succinate 
lurasidone 
LY-165163 
LY294002  
magnesium sulfate +   
magnesium(2+) +  
maleimide +   
maleimides +   
Malonoben  
malyngamide A 
Mecarphon 
meclofenamic acid  
melatonin +   
mephenytoin  
mephobarbital  
mercaptoethanol +   
metergoline  
metformin  
methiothepin  
Methylergonovine Maleate  
metoprolol  
mianserin +   
mianserin hydrochloride 
midazolam +   
midazolam hydrochloride 
minocycline +   
minocycline hydrochloride 
morphine +   
myricetin +   
myxothiazol  
N(1)-[(3R)-1-((2S)-2-\{[(benzyloxy)carbonyl]amino\}-4-methylpentyl)-4-oxopyrrolidin-3-yl]-N(2)-[(pyridin-4-ylmethoxy)carbonyl]-L-leucinamide 
N(2)-[(benzyloxy)carbonyl]-N(1)-((3R)-1-\{N-[(benzyloxy)carbonyl]-L-leucyl\}-4-oxopyrrolidin-3-yl)-L-leucinamide 
N(5)-ethyl-L-glutamine 
N,N-dimethylformamide +   
N-(3,4-dihydro-2H-pyrrol-5-yl)-5-(2-furanyl)-1,3,4-oxadiazol-2-amine 
N-[(3S)-2-oxo-1-(1H-pyrrolo[2,3-c]pyridin-2-ylmethyl)pyrrolidin-3-yl]thieno[3,2-b]pyridine-2-sulfonamide 
N-[3-(aminomethyl)benzyl]acetamidine  
N-\{[2-(3-chloro-4-fluorophenyl)hydrazino]carbonyl\}-3,5-bis(methylthio)isothiazole-4-carboxamide 
N-acetyl-L-cysteine +   
N-arachidonoylserotonin 
N-bromosuccinimide 
N-chlorosuccinimide 
N-ethylsuccinimide +  
N-iodosuccinimide 
N-nitrosodimethylamine  
N-Phenylacetyl pyroglutamic acid 
N-ribosylnicotinamide  
N-succinimidyl N-methylcarbamate 
NAD zwitterion  
naphthalene-1,2,3,4-tetrone +  
naphthazarin  
naxagolide 
naxagolide hydrochloride 
nebivolol  
nemadipine-A 
nicardipine  
nicardipine hydrochloride 
nickel dichloride +   
nicotinamide +   
nifedipine  
nimetazepam  
nimodipine  
nisoldipine  
nitrazepam +   
nitrendipine  
nitroflurbiprofen  
nordazepam  
nordihydroguaiaretic acid +   
Nortriptyline hydrochloride 
norverapamil  
nygerone A 
ochratoxin A +   
ochratoxin B  
oleoyl ethanolamide +   
omega-conotoxin GVIA  
omeprazole +   
otophylloside B 
oxaloacetic acid +   
Oxatomide  
oxcarbazepine  
oxoproline +   
oxybutynin +   
palmitoyl ethanolamide  
Palmyrrolinone 
paracetamol +   
paraquat +   
perampanel +  
perampanel hydrate 
pergolide mesylate 
perylenediimide 
pestalamide A 
pestalamide B 
phenformin  
phenobarbital +   
phenytoin  
phosphonoformic acid +   
phthalimides +   
piceatannol +  
piCRAC-1 +  
pioglitazone +   
piperidine-2,6-dione +   
Piplartine  
pomalidomide  
PP2 
pregabalin  
prilocaine +  
primidone  
promethazine hydrochloride 
propofol +   
pyflubumide 
pyroglutamine 
pyrrolidin-2-ones +   
pyrrolidine dithiocarbamate  
QSY35 succinimidyl ester 
quercetin +   
quercetin 3-O-beta-D-glucopyranoside  
quinidine sulfate 
resveratrol +   
rifampicin +   
RK-24466 
SB 203580  
simvastatin  
sirolimus +   
SKF-96365 hydrochloride  
sodium butyrate 
sodium meclofenamate monohydrate 
sodium phenylbutyrate 
sodium selenate 
sodium valproate +   
solasodine +   
solasodine(1+) 
spermidine +   
staurosporine +   
streptolydigin 
SU4312 
succinimide +  
tandospirone 
tannic acid 
tarocin A 
tarocin A1 
tarocin A2 
terrylendiimide 
Tetraacetylethylenediamine 
thalidomide +   
thapsigargin  
thioflavine T  
thiopental  
thioridazine hydrochloride 
tiagabine  
tiagabine hydrochloride 
topiramate  
trametinib +   
tranilast  
trans-caffeic acid +   
trans-piceid  
trichostatin A +   
Trimethadione 
trioctanoin 
tris(picolinato)chromium  
troglitazone  
tyrphostin 1 
tyrphostin AG 1478  
tyrphostin B42  
U50488  
Unii-73hdp58zfk 
Urolithin A  
ursolic acid +   
valproate semisodium 
valproic acid +   
valpromide  
vanillin +   
verapamil  
vigabatrin  
vincristine sulfate 
Vinpocetine  
wortmannin +   
xi-4,5-Dihydro-2,4(5)-dimethyl-1H-imidazole 
zaleplon  
zofenopril 
zofenopril calcium 
zofenoprilat 
zofenoprilat arginine 
zonisamide  

Synonyms
Exact Synonyms: 3-ethyl-3-methylpyrrolidine-2,5-dione
Related Synonyms: 2-ethyl-2-methylsuccinimide ;   2-methyl-2-ethylsuccinimide ;   3-ethyl-3-methyl-2,5-pyrrolidinedione ;   3-ethyl-3-methylsuccinimide ;   3-methyl-3-ethylpyrrolidine-2,5-dione ;   3-methyl-3-ethylsuccinimide ;   Aethosuximide ;   Formula=C7H11NO2 ;   InChI=1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10) ;   InChIKey=HAPOVYFOVVWLRS-UHFFFAOYSA-N ;   SMILES=CCC1(C)CC(=O)NC1=O ;   alpha-ethyl-alpha-methylsuccinimide ;   alpha-methyl-alpha-ethylsuccinimide ;   ethosuximidum ;   etosuximida ;   gamma-methyl-gamma-ethyl-succinimide
Alternate IDs: CHEBI:131811
Xrefs: CAS:77-67-8 ;   Chemspider:3175 ;   DrugBank:DB00593 ;   Drug_Central:1087 ;   HMDB:HMDB0014731 ;   KEGG:C07505 ;   KEGG:D00539 ;   LINCS:LSM-5195
Xref Mesh: MESH:D005013
Xrefs: PMID:12873507 ;   PMID:16606760 ;   PMID:1681105 ;   PMID:17011080 ;   PMID:17046248 ;   PMID:17451232 ;   PMID:17481896 ;   PMID:1847429 ;   PMID:18949032 ;   PMID:19005061 ;   PMID:1992141 ;   PMID:2061925 ;   PMID:21332949 ;   PMID:21945797 ;   PMID:2296016 ;   PMID:2308142 ;   PMID:3336019 ;   PMID:3820228 ;   PMID:8246220 ;   PMID:8627613 ;   PMID:8691481 ;   PMID:9016327 ;   Reaxys:117054 ;   Wikipedia:Ethosuximide

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