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Ontology Browser
Term:
2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine (CHEBI:44811)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0) Naked Mole-rat: (0) Green Monkey: (0)
Parent Terms Term With Siblings Child Terms
(+)-(12E,2S,3S,4R,5R,6R,9S,11S,15R)-3-benzoyloxy-5,6-epoxylathyr-12-en-15-ol-14-one 
(+-)-menthol 
(-)-(12E,2S,3S,4R,5R,6R,9S,11S,15R)-3-acetoxy-15-benzoyloxy-5,6-epoxylathyr-12-en-14-one 
(-)-(5E,12E,2S,3S,4S,9S,11S,15R)-15-benzoyloxylathyra-5,12-dien-3-ol-14-one 
(-)-(6Z,12E,2S,3S,4R,5R,9S,11S,15R)-3-acetoxy-15-benzoyloxylathyra-6,12-dien-5-ol-14-one 
(-)-(6Z,12E,2S,3S,4R,5R,9S,11S,15R)-5-acetoxy-15-benzoyloxylathyra-6,12-dien-3-ol-14-one 
(2R,3S,2'R)-nadolol +   
(E)-cinnamaldehyde +   
(R)-adrenaline +   
(R)-nicardipine +   
(S)-nicardipine +   
(S)-timolol (anhydrous) +   
(S)-timolol hemihydrate 
(S)-timolol maleate 
1,3-dinitroglycerol +  
1-[(9Z)-hexadecenyl]-2-acetyl-sn-glycero-3-phosphocholine 
1-decyl-2-acetyl-sn-glycero-3-phosphocholine 
1-dodecyl-2-acetyl-sn-glycero-3-phosphocholine 
1-tetradecyl-2-acetyl-sn-glycero-3-phosphocholine 
15beta-O-benzoyl-5alpha-hydroxyisolathyrol 
2-hydroxyoleic acid 
2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine 
A 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine betaine which has hexadecyl as the alkyl group. PAF is a potent phospholipid activator and mediator of many leukocyte functions, including platelet aggregation, inflammation, and anaphylaxis.
2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine  
3-pyridinemethanol 
4-hydroxychalcone  
4-phenyl-3-furoxancarbonitrile  
5beta-dihydrotestosterone 
6-aminohexanoic acid +   
6-O-galloyl-beta-D-glucose 
7-epiclusianone 
8-epi-prostaglandin E2  
8-epi-prostaglandin F2alpha +   
acebutolol  
acebutolol hydrochloride 
acetylcholine +   
ACT-132577 +   
ACT-333679 +  
adenosine +   
ajmalicine  
alfuzosin +   
alginic acid  
aliskiren +   
aliskiren fumarate 
alpha-methyl-L-dopa +   
alpha-methyl-L-dopa ethyl ester 
alpha-methyl-L-tyrosine 
alprenolol +   
aminoethyl nitrate +  
amlodipine +   
amlodipine benzenesulfonate +  
anandamide +   
angiotensin (1-9) 
angiotensin (1-9) dizwitterion 
anticoagulant +   
apelin-13 
Arg-Phe 
argipressin  
asenapine  
asenapine maleate 
atenolol +   
auraptene  
avanafil 
azilsartan +   
azilsartan kamedoxomil 
azilsartan medoxomil 
bamethan +  
BAY 41-2272 
bendroflumethiazide +   
benzthiazide 
benzyl nicotinate 
bepridil +   
beraprost  
beraprost sodium 
betahistine  
betaxolol +   
betaxolol hydrochloride +  
bethanidine +  
bethanidine sulfate 
bevantolol +   
bevantolol hydrochloride +  
bexagliflozin  
bimatoprost 
bisoprolol +   
bopindolol  
bosentan +   
bradykinin +   
bretylium +   
bretylium tosylate  
brimonidine +   
bucladesine  
Byvalson 
camostat  
camostat mesylate 
candesartan  
captopril +   
carbon dioxide  
carbon monoxide  
carmoxirole  
carmoxirole hydrochloride 
carpronium chloride 
carteolol  
carteolol hydrochloride 
carvedilol  
cassaine 
CGP 12177  
CGP-42112A  
chlorothiazide 
cilazapril +   
cilazapril monohydrate  
cilnidipine  
cilostazol  
cinaciguat  
cleistanthin A 
cleistanthin B +  
clonidine +   
clonixin 
clonixin lysine salt 
colforsin daropate 
colforsin daropate hydrochloride  
convallatoxin 
corilagin  
cyclandelate 
cyclothiazide  
debrisoquin +   
dermatan sulfate  
devapamil 
diallyl trisulfide  
diazoxide  
dihydroergocristine +  
dihydroergocristine mesylate +  
dilazep  
dilazep dihydrochloride 
diltiazem  
diltiazem hydrochloride 
diltiazem(1+) +  
dinitrogen oxide  
diosmetin +   
dipyridamole  
dorzolamide +   
dorzolamide hydrochloride  
dotarizine 
doxazosin +   
droxidopa 
dyphylline +  
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor +   
efonidipine 
enalapril +   
enalapril maleate 
enalaprilat (anhydrous) +   
enalaprilat dihydrate  
enrasentan  
eplerenone  
eprosartan +   
eprosartan methanesulfonate 
ergoloid mesylate 
erythrityl tetranitrate 
esatenolol 
esmolol +   
esmolol hydrochloride 
eupatorin  
fasudil  
fasudil hydrochloride +  
fasudil hydrochloride hydrate 
felodipine  
fenoldopam  
fluprostenol +   
forasartan 
forskolin +   
fosinopril  
fosinopril sodium 
fosinoprilat +   
graminone B 
grayanotoxin I 
GSK2181236A  
guanadrel 
guanadrel sulfate 
guanethidine +   
guanethidine monosulfate +  
guanethidine sulfate 
HU-308  
hydralazine +   
hydralazine hydrochloride 
hydrochlorothiazide  
hydroflumethiazide 
hydrogen sulfide +   
icatibant +   
icatibant acetate 
ICI 118551  
Ile(5)-angiotensin II (1-7)  
iloprost  
imidapril +   
imidaprilat  
indanomycin 
indapamide  
iodocyanopindolol  
irbesartan  
isoamyl nitrite 
isopropyl unoprostone 
isosorbide dinitrate  
isosorbide mononitrate  
itramin tosilate 
JWH-133 
kaempferide +   
ketanserin  
ketanserin tartrate 
khellin 
labetalol  
latanoprost  
latanoprost free acid +   
leukotriene C4 +   
leukotriene D4  
levobunolol +   
levobunolol hydrochloride 
levosimendan 
lificiguat 
lisinopril dihydrate  
lofexidine 
losartan +   
macitentan  
methacholine +   
methyl brevifolincarboxylate 
metipranolol  
metipranolol hydrochloride 
metolazone  
metoprolol  
milrinone  
minoxidil  
mirodenafil 
molsidomine  
morin  
morphine +   
N-arachidonoyl-L-serine 
N-ethyl-5'-carboxamidoadenosine  
n-pentyl nitrite 
nadolol  
nebivolol  
nebivolol hydrochloride +  
nelociguat 
nerolidol +   
nicardipine  
nicorandil  
nicotinic acid +   
nifedipine  
nimodipine  
nisoldipine  
nitrendipine  
nitric oxide  
nitroflurbiprofen  
nitroglycerin  
norverapamil  
oleuropein +   
olmesartan  
oxytocin +   
palmitoyl ethanolamide  
papaverine  
partial prostacyclin agonist +  
penbutolol sulfate 
pentaerythritol tetranitrate  
pentamethonium +  
pentamethonium bromide 
pentolinium tartrate  
perindopril  
perindopril arginine +  
perindopril erbumine 
perindoprilat 
petasin 
phentolamine  
pimobendan  
pindolol +   
pinocembrin +   
platelet aggregation inhibitor +   
poly(vinylpyrrolidone) +   
PP2 
practolol  
praliciguat 
pratosartan 
prazosin +   
Prestalia 
propranolol +   
prostaglandin E1 +   
quinapril 
quinapril hydrochloride  
quinaprilat  
quinethazone 
remikiren 
rescinnamine  
reserpine  
riociguat  
rottlerin  
S-nitroso-L-cysteine +   
S-nitroso-N-acetyl-D-penicillamine  
scoparone  
selexipag 
sildenafil +   
sildenafil citrate  
sodium alginate 
sodium nitrite  
sodium nitroprusside +  
sodium nitroprusside dihydrate 
sotagliflozin 
sotalol  
sotalol hydrochloride 
sparsentan 
spathulenol  
sphingosine 1-phosphate  
spirapril  
spiraprilat +   
spironolactone  
substance P 
tadalafil  
telmisartan  
terazosin +   
tetragalacturonic acid hydroxymethylester 
tetramethylpyrazine  
theobromine  
theophylline +   
ticlopidine +   
tienilic acid  
tolazoline  
torasemide +   
trandolapril  
trandolaprilat +   
tranexamic acid  
travoprost 
treprostinil +   
triacsin C  
trichlormethiazide  
trimethaphan +   
trimethaphan camsylate 
troglitazone  
unoprostone +  
valsartan +   
vardenafil 
verapamil  
vericiguat 
vincamine  
visnagin 
xyloketal B 
zofenopril 
zofenopril calcium 
zofenoprilat 
zofenoprilat arginine 
zolasartan 

Synonyms
Exact Synonyms: (2R)-2-acetoxy-3-(hexadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate
Related Synonyms: (R)-7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphapentacosan-1-aminium hydroxide inner salt 4-oxide ;   1-O-hexadecyl PAF ;   1-O-hexadecyl-2-O-acetyl-sn-glycero-3-phosophocholine ;   1-O-hexadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine ;   1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine ;   1-O-hexadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine ;   1-O-hexadecyl-platelet-activating factor ;   1-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine ;   C16 PAF ;   C16:0 PAF ;   Formula=C26H54NO7P ;   InChI=1S/C26H54NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-31-23-26(34-25(2)28)24-33-35(29,30)32-22-20-27(3,4)5/h26H,6-24H2,1-5H3/t26-/m1/s1 ;   InChIKey=HVAUUPRFYPCOCA-AREMUKBSSA-N ;   PAF ;   SMILES=CCCCCCCCCCCCCCCCOC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(C)=O ;   platelet-activating factor ;   platelet-activating factor C16
Xrefs: CAS:74389-68-7 ;   DrugBank:DB02261 ;   LIPID_MAPS_instance:LMGP01020046 ;   PDBeChem:PFS ;   PMID:19075994 ;   PMID:19827129 ;   PMID:20431963 ;   PMID:21347278 ;   PMID:21804199 ;   PMID:22924390 ;   PMID:23169529 ;   Reaxys:3574588 ;   Wikipedia:Platelet-activating_factor

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