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(-)-cotinine +   
(-)-secoisolariciresinol +   
(1S,5R)-3-(6,11-dihydro-5H-dibenzo[1,2-a:1',2'-e][7]annulen-11-yloxy)-8-methyl-8-azabicyclo[3.2.1]octane 
(R)-fluoxetine +   
(R)-fluoxetine hydrochloride +  
(R)-methocarbamol +  
(S)-(-)-sulpiride 
(S)-duloxetine hydrochloride  
(S)-fluoxetine +   
(S)-fluoxetine hydrochloride +  
(S)-glaucine +   
(S)-methocarbamol +  
1-(2,4-dichloro-10,11-dihydrodibenzo[a,d][7]annulen-5-yl)imidazole +  
2-(trifluoromethylsulfonyl)-6,11-dihydro-5H-dibenzo[1,3-e:1',2'-f][7]annulen-11-ol 
2-bromo-5,6-dihydrodibenzo[3,1-[7]annulen-11-one 
3-(11-dibenzo[1,2-a:1',2'-e][7]annulenylidene)-N-methyl-1-propanamine 
4-(1-benzofuran-2-yl)pyridine 
7,8-dihydroxyflavone 
8,8-dimethyl-2-oxo-7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-7-yl (2Z)-2-methyl-2-butenoate 
8-bromo-3',5'-cyclic GMP  
adinazolam  
alcuronium +   
all-cis-5,8,11,14,17-icosapentaenoic acid +  
alprazolam  
AM-251  
amineptine +  
amitriptyline +   
Amitriptyline hydrochloride 
amitriptylinoxide  
amoxapine  
ANA-12 
antimanic drug +   
antipsychotic agent +   
antispasmodic drug +   
anxiolytic drug +   
aprepitant  
atomoxetine +   
atomoxetine hydrochloride  
atracurium +   
atracurium besylate +  
azumolene 
azure B  
baclofen  
beta-erythroidine +   
brexanolone 
bupropion +   
butriptyline 
carbotricyclic compound +   
carfentanil  
carisoprodol +   
chanoclavine-I +  
chanoclavine-I aldehyde 
chlormezanone +  
chlorphenamine +   
chlorphenesin +   
chlorphenesin carbamate  
chlorzoxazone  
cisatracurium +   
cisatracurium besylate 
citalopram  
citalopram hydrobromide 
clomipramine  
clomipramine hydrochloride 
clorgyline  
clovoxamine 
cycloaraneosene 
cyclobenzaprine +   
5-Methylidene-5H-dibenzo[a,d]cycloheptene in which one of the hydrogens of the methylidene group is substituted by a 2-(dimethylamino)ethyl group. A centrally acting skeletal muscle relaxant, it is used as its hydrochloride salt in the symptomatic treatment of painful muscle spasm.
cyclobenzaprine hydrochloride 
dantrolene  
dantrolene sodium hemiheptahydrate 
decamethonium  
desipramine +   
desmethyldoxepin +  
dexamisole +  
Dizocilpine 
dothiepin +   
dothiepin hydrochloride +  
doxacurium +  
doxacurium chloride 
doxepin +   
dyphylline +  
eperisone 
escitalopram +   
escitalopram hydrobromide +  
etazolate  
ethyl (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate 
flibanserin 
fluoxetine  
fluoxetine hydrochloride 
flupenthixol  
fluvoxamine  
forskoditerpenoside C 
forskoditerpenoside D 
forskoditerpenoside E 
funalenone 
gallamine 
ginsenoside Rb3 
hyperforin  
hypericin +   
imipramine +   
imipramine hydrochloride 
kaempferol 3,7-di-O-alpha-L-rhamnoside 
L-tryptophan +   
lamotrigine  
lithium citrate tetrahydrate 
lithium sulfate  
lofepramine +   
lofepramine hydrochloride 
LSM-20934 
LSM-36879 
LSM-37036 
LSM-37055 
LSM-37155 
LSM-5387 
LSM-5782 
memantine  
memantine hydrochloride 
methocarbamol 
methylene blue  
mianserin +   
midazolam +   
midazolam hydrochloride 
minaprine +  
miquelianin  
moclobemide  
N-acetylphenylalanine +  
N2,N2,N9,N9-tetramethyl-11-oxo-5,6-dihydrodibenzo[3,1-b:3',1'-f][7]annulene-2,9-disulfonamide 
N2,N9-dimethyl-11-oxo-5,6-dihydrodibenzo[3,1-b:3',1'-f][7]annulene-2,9-disulfonamide 
nefazodone +   
nisoxetine  
nitroglycerin  
nortriptyline  
Nortriptyline hydrochloride 
noxiptiline 
O-desmethylvenlafaxine 
organic heterotricyclic compound +   
orphenadrine +   
orphenadrine citrate 
orphenadrine hydrochloride 
oxybutynin +   
pancuronium +   
pancuronium bromide 
paroxetine +   
paroxetine hydrochloride 
paroxetine maleate 
piroheptine 
Piroheptine hydrochloride 
presilphiperfolan-8beta-ol 
pridinol  
protriptyline +   
protriptyline hydrochloride 
quinine +   
quinine(1+) +   
ritanserin  
rocuronium +   
rocuronium bromide 
rolipram +   
rubidium chloride 
salvianolic acid B  
scopolamine +   
sertraline  
sertraline hydrochloride 
setiptiline 
sodium 8-bromo-3',5'-cyclic GMP 
St. John's wort extract 
succinylcholine +   
succinylcholine chloride (anhydrous) +  
succinylcholine chloride dihydrate 
sulpiride +   
tetracyclic antidepressant +   
tetrindole 
tetrindole hydrochloride 
tetrindole mesylate 
theophylline +   
tizanidine  
tolterodine +   
tranylcypromine  
tranylcypromine hydrochloride 
trazodone +   
trazodone hydrochloride 
tricyclic diterpenoid +  
trimipramine +   
trimipramine maleate 
tubocurarine  
vecuronium +   
vecuronium bromide  
venlafaxine +   
vilazodone 
vilazodone hydrochloride 
vortioxetine  
vortioxetine hydrobromide 

Synonyms
Exact Synonyms: 3-(5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine ;   3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine
Related Synonyms: (3-Dibenzo[a,d]cyclohepten-5-ylidene-propyl)-dimethyl-amine ;   Formula=C20H21N ;   InChI=1S/C20H21N/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-14H,7,15H2,1-2H3 ;   InChIKey=JURKNVYFZMSNLP-UHFFFAOYSA-N ;   N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-Delta(5,gamma)-propylamine ;   SMILES=CN(C)CCC=C1c2ccccc2C=Cc2ccccc12 ;   ciclobenzaprina ;   cyclobenzaprinum
Alternate IDs: CHEBI:128119
Xrefs: Beilstein:2126383 "Beilstein" ;   CAS:303-53-7 "KEGG COMPOUND" ;   CAS:303-53-7 "NIST Chemistry WebBook" ;   DrugBank:DB00924 ;   Drug_Central:751 "DrugCentral" ;   KEGG:C06931 ;   KEGG:D07758 ;   LINCS:LSM-5537
Xref Mesh: MESH:C004704
Xrefs: PMID:17725338 "ChEMBL" ;   PMID:18027916 "ChEMBL" ;   Patent:GB858187 ;   Wikipedia:Cyclobenzaprine

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.