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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
colistin A +     
colistin B +     
peptide antibiotic +     
polymyxin +     
2-(glutathion-S-yl)-1,4-hydroquinone 
A41030A 
A47934 
adefovir +   
adefovir pivoxil  
aureobasidin A 
bacilysin 
bacteriocin 
capreomycin +  
chelate-forming peptide +   
chloropeptin I 
chloropeptin II 
chromopeptide +   
colistimethate 
colistimethate A +  
colistimethate B +  
colistimethate sodium 
colistin +   
A multi-component mixture comprising mostly of colistin A (R = Me) and B (R = H), with small amounts of colistin C and other polymyxins, produced by certain strains of Bacillus polymyxa var. colistinus. An antibiotic, it is used as its sulfate salt (for oral or topical use) or as the sodium salt of the N-methylsulfonic acid derivative (the injectable form) in the treatment of severe Gram-negative infections, partiularly those due to Pseudomonas aeruginosa.
colistin A +   
colistin A sodium methanesulfonate +  
colistin B +   
colistin B sodium methanesulfonate +  
glomosporin 
iopromide  
lantibiotic +  
lipopeptide antibiotic +   
lugdunin 
methoxyflurane  
microcin +  
nitrilotriacetic acid +  
polymyxin B1 
polymyxin B2  
SGX-523 
sodium nitrilotriacetate 
teixobactin 
tetrachloroethene  
tyrocidine A +  
tyrocidine B +  
tyrocidine C +  
tyrocidine D +  
UK 63052 
UK 63598 
UK 65662 
vancomycin aglycone +   
viomycin +  

Synonyms
Related Synonyms: Formula=C52H97N16O13R ;   SMILES=CC[C@@H](C)CCCCC(=O)N[C@@H](CCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCN)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCN)NC1=O)[C@@H](C)O ;   colistina ;   colistine ;   colistinum ;   polymyxin E
Alternate IDs: CHEBI:34651 ;   CHEBI:472593 ;   CHEBI:560465 ;   CHEBI:566816 ;   CHEBI:596826 ;   CHEBI:597111 ;   CHEBI:600596 ;   CHEBI:659853
Xrefs: CAS:1066-17-7 "ChemIDplus" ;   CAS:1264-72-8 "ChemIDplus" ;   CAS:1264-72-8 "KEGG COMPOUND" ;   DrugBank:DB00803 ;   KEGG:C13768 ;   KEGG:D02138
Xref Mesh: MESH:D003091
Xrefs: PMID:15825037 "Europe PMC" ;   PMID:16931410 "Europe PMC" ;   PMID:17145797 "ChEMBL" ;   PMID:17562800 "ChEMBL" ;   PMID:17576842 "ChEMBL" ;   PMID:17606684 "ChEMBL" ;   PMID:17620384 "ChEMBL" ;   PMID:17646423 "ChEMBL" ;   PMID:17846127 "ChEMBL" ;   PMID:17876007 "ChEMBL" ;   PMID:18625681 "Europe PMC" ;   PMID:25322351 "Europe PMC" ;   PMID:26252512 "Europe PMC" ;   PMID:26415906 "Europe PMC" ;   PMID:26488563 "Europe PMC" ;   PMID:26730548 "Europe PMC" ;   PMID:27160031 "Europe PMC" ;   PMID:27411324 "Europe PMC" ;   PMID:27480806 "Europe PMC" ;   PMID:27524102 "Europe PMC" ;   PMID:27552304 "Europe PMC" ;   PMID:27684296 "Europe PMC" ;   PMID:27743779 "Europe PMC" ;   PMID:27790432 "Europe PMC" ;   PMID:27793510 "Europe PMC" ;   PMID:27891118 "Europe PMC" ;   PMID:27917926 "Europe PMC" ;   PMID:28018876 "Europe PMC" ;   PMID:28029008 "Europe PMC" ;   PMID:28215823 "Europe PMC" ;   PMID:28257552 "Europe PMC" ;   PMID:28267594 "Europe PMC" ;   PMID:28267779 "Europe PMC" ;   PMID:28300674 "Europe PMC" ;   PMID:28315729 "Europe PMC" ;   PMID:28321410 "Europe PMC"

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.