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Ontology Browser

Term:
trypanothione disulfide (CHEBI:35490)
Annotations: Rat: (1) Mouse: (1) Human: (1) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
organic disulfide +     
2,2'-dithiobis\ 
2,2'-dithiobis\ 
2,2'-dithiodiethanol  
2-(methyldithio)pyridine-N-oxide 
3-(\{cis-4-[(2-\{[2-(acetylamino)ethyl]disulfanyl\}ethyl)carbamoyl]cyclohexyl\}carbamoyl)pyrazine-2-carboxylic acid 
4,4'-dipyridyl disulfide  
4,4'-disulfanyldibutanoic acid 
6,6'-dithiobis\ 
6,6'-dithiodi[1-(2-acetamido-4-amino-2,4-dideoxy-alpha-D-fucosyloxy)hexane] 
6,6'-dithiodi[1-(alpha-D-galacturonosyloxy)hexane] 
6,6'-dithiodi\ 
aldrithiol  
allyl methyl disulfide  
aranotin 
bis(2-methylundecan-2-yl) disulfide 
captopril disulfide 
chetomin  
cholesteryl 6-O-[15-(ethyldisulfanyl)pentadecanoyl]-beta-D-galactoside 
cis-1,2-dithiane-4,5-diol 
cis-4,5-bis(trimethylsiloxy)-1,2-dithiane 
CoA-disulfide 
CoA-glutathione 
CoA-glutathione(5-) 
CoM-S-S-CoB 
Cys-Gly disulfide 
cystamine  
cystine +   
D-penicillamine disulfide 
diallyl disulfide  
dibenzothiazol-2-yl disulfide  
dibenzyl disulfide 
dimethyl disulfide 
dipropyl disulfide  
disulfiram  
dithionitrobenzoic acid  
eptifibatide  
GCB 
glionitrin A 
gliotoxin  
glutathione amide disulfide 
glutathione amide disulfide dizwitterion 
glutathione disulfide  
homocystines +  
IPA-3 
L-cysteine glutathione disulfide 
L-cystine di-2-naphthylamide 
L-cystine mono-2-naphthylamide 
lehualide K 
lepirudin  
Methyl (methylthio)methyl disulfide 
methyl 6-O-[15-(ethyldisulfanyl)pentadecanoyl]-beta-D-galactoside 
Methyl propyl disulfide 
mycothione 
N,N'-[disulfanediyldi(ethane-2,1-diyl)]bis[2-(1H-indol-3-yl)ethan-1-amine] 
N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[5-hydroxy-3-(2-oxolanylmethyldisulfanyl)pent-2-en-2-yl]formamide 
omega-conotoxin GVIA  
ovothiol A disulfide 
pantethine 
phenyl 6-O-[15-(ethyldisulfanyl)pentadecanoyl]-beta-D-galactoside 
romidepsin  
rostratin A 
rostratin B 
rostratin C 
rostratin D 
somocystinamide A 
spiruchostatin B  
Thiamine disulfide 
thiocyanogen 
thiram  
trans-1,2-dithiane-4,5-diol +  
trypanothione disulfide  
An organic disulfide resulting from the formal oxidative coupling of the thiol groups of N(1),N(8)-bis(glutathionyl)-spermidine from the insect-parasitic trypanosomatid Crithidia fasciculata.

Synonyms
Exact Synonyms: (2S,2'S)-5,5'-{[(4R,23R)-5,8,19,22-tetraoxo-1,2-dithia-6,9,13,18,21-pentaazacyclotetracosane-4,23-diyl]diimino}bis(2-amino-5-oxopentanoic acid)
Related Synonyms: 2-AMINO-4-[4-(4-AMINO-4-CARBOXY-BUTYRYLAMINO)-5,8,19,22-TETRAOXO-1,2-DITHIA-6,9,13,18,21-PENTAAZA-CYCLOTETRACOS-23-YLCARBAMOYL]-BUTYRIC ACID ;   Formula=C27H47N9O10S2 ;   InChI=1S/C27H47N9O10S2/c28-16(26(43)44)4-6-20(37)35-18-14-47-48-15-19(36-21(38)7-5-17(29)27(45)46)25(42)34-13-23(40)32-11-3-9-30-8-1-2-10-31-22(39)12-33-24(18)41/h16-19,30H,1-15,28-29H2,(H,31,39)(H,32,40)(H,33,41)(H,34,42)(H,35,37)(H,36,38)(H,43,44)(H,45,46)/t16-,17-,18-,19-/m0/s1 ;   InChIKey=LZMSXDHGHZKXJD-VJANTYMQSA-N ;   Oxidized trypanothione ;   SMILES=N[C@@H](CCC(=O)N[C@H]1CSSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(=O)NCCCNCCCCNC(=O)CNC1=O)C(O)=O ;   TSST ;   Trypanothiondisulfid
Alternate IDs: CHEBI:15273 ;   CHEBI:46005 ;   CHEBI:8800
Xrefs: Beilstein:3645155 ;   CAS:96304-42-6 ;   KEGG:C03170
Xref Mesh: MESH:C044809
Xrefs: PDBeChem:TS2
Cyclic Relationships: is_conjugate_base_of CHEBI:58661

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.