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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
(1S,3aR,3bR,5aS,9aS,9bR,11aS)-1-hydroxy-1,9a,11a-trimethyl-2,3,3a,3b,4,5,5a,6,9,9b,10,11-dodecahydroindeno[4,5-h]isochromen-7-one 
(22E,24R)-ergosta-5alpha,6alpha-epoxide-8,22-diene-3beta,7alpha-diol 
(24S,25)-epoxy-7alpha-hydroxycholesterol 
(3beta,24R,24'R)-fucosterol epoxide 
(3beta,9xi)-3,14-Dihydroxycarda-5,20(22)-dienolide 
(5-Acetyloxy-9,18-dihydroxy-2,6,10-trimethyl-16-oxo-14-pyridin-3-yl-11,15-dioxatetracyclo[8.8.0.02,7.012,17]octadeca-12(17),13-dien-6-yl)methyl acetate 
(9S,14S)-10,13-Dimethylspiro[2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione 
10,13-dimethyl-7-methylsulfinylspiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione 
10,13-dimethylspiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione 
17-Hydroxy-3-oxo-17alpha-pregna-1,4-diene-21-carboxylic acid, gamma-lactone 
17-Hydroxy-3-oxo-19-nor-5alpha,17alpha-pregnane-21-carboxylic acid, gamma-lactone 
17-Hydroxy-3-oxo-19-nor-5beta,17alpha-pregnane-21-carboxylic acid, gamma-lactone 
17alpha-hydroxywithanolide D 
17beta-Acetyl-1,2,3,4,6alpha,7alpha,10,12,13,14alpha,16,17-dodecahydro-3beta-hydroxy-10beta,13beta-dimethyl-5beta,8beta-etheno-15H-cyclopenta[a]phenanthrene-6,7-dicarboxylic anhydride acetate 
17beta-Hydroxy-2-oxa-5alpha-androstan-3-one 
17beta-Hydroxy-4-oxa-5alpha-androstan-3-one acetate 
2,3-dihydro-3beta-methoxy withaferin A 
2,3-dihydro-3beta-O-sulfate withaferin A 
2,3-dihydrowithaferin A 
20-hydroxytubocapsanolide A 
23-hydroxytubocapsanolide A 
24(S),25-epoxycholesterol 
3,14-Dihydroxycarda-5,20(22)-dienolide 
3-hydroxy-9a,11a-dimethyl-3,3a,3b,8,9,9b,10,11-octahydro-2H-spiro[cyclopenta[a]phenanthrene-1,2'-oxolane]-5',7-dione 
3-oxo-24,25,26,27-tetranortirucall-7-ene-23(21)-lactone 
3beta-hydroxy-16alpha,17alpha-epoxypregnenolone +  
3beta-hydroxy-16alpha,17alpha-epoxypregnenolone 3-beta-D-glucoside 
4-methanesulfonyl-9a,11a-dimethyl-3,3a,3b,4,5,8,9,9b,10,11-decahydro-2H-spiro[cyclopenta[a]phenanthrene-1,2'-oxolane]-5',7-dione 
5,6alpha-epoxy-5alpha-cholestan-3beta-ol  
5,6alpha-epoxy-5alpha-cholestane 
5,6beta-epoxy-5alpha-cholestan-3beta-ol 
5-(3,14-Dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl)pyran-2-one 
5-[14-hydroxy-10,13-dimethyl-3-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-2-oxanyl]oxy]-1,2,3,6,7,8,9,11,12,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-pyranone 
5-hydroxy-4-methanesulfinyl-9a,11a-dimethyl-3,3a,3b,4,5,8,9,9b,10,11-decahydro-2H-spiro[cyclopenta[a]phenanthrene-1,2'-oxolane]-5',7-dione 
5-hydroxy-4-methanesulfonyl-9a,11a-dimethyl-3,3a,3b,4,5,8,9,9b,10,11-decahydro-2H-spiro[cyclopenta[a]phenanthrene-1,2'-oxolane]-5',7-dione 
5alpha-bufanolide 
5beta-bufanolide +   
6,7-dihydrocanrenone 
6-hydroxy-7-(thiomethyl)spironolactone 
7 -thiospironolactone 
7-Acetoxy-6-hydroxylimonin 
7-deacetyl-7-benzoylepoxyazadiradione 
7-nor-ergosterolide 
7-thiomethylspironolactone 
7alpha-Hydroxyparavallarine 
9,11alpha-epoxypregn-4-ene-3,20-dione 
abrusoside A 
ajugalactone 
aplysiallene 
brazilein  
Bryophyllin A 
bryotoxin A 
bufadienolides +   
bufalin  
bufanolide +   
bufogenin  
A steroid lactone of Chan su (toad venom), a Chinese medicine obtained from the skin venom gland of toads. A specific Na/K-ATPase protein inhibitor, it is used as a cardiotonic and central nervous system (CNS) respiratory agent, an analgesic and anesthetic, and as a remedy for ulcers.
Bufotalin 
Calamin 
calcitriol 26,23-lactone 
canrenone 
cardanolide +   
cardenolides +   
cardiac glycoside +   
cassaidine 
cassaine 
cholestanol 7alpha,8alpha-epoxide 
cholesterol beta-epoxide 
Cinobufagin  
Cinobufotalin  
convallatoxin 
cyasterone 
Cyclocalamin 
D-Homo-A-nor-17a-oxaandrost-3(5)-ene-2,17-dione 
Deacetylnomilinic acid 
Deacetylspironolactone 
deacetyltanghinin 
debromolaurinterol 
deslanoside 
Desoxylimonin 
Dicirenone 
digitoxin +   
digoxin +   
dihydroouabain  
drospirenone  
elaeodendroside B 
elaeodendroside F 
elaeodendroside G 
elaeodendroside T 
elaeodendroside V 
elaeodendroside W 
eplerenone  
ethanethioic acid S-(10,13-dimethyl-3,5'-dioxo-7-spiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]yl) ester 
Eurycomalactone 
Gamabufogenin 
Glucoscilliroside 
Hellebrigenin 3-acetate 
Hellebrigenin glucoside 
Icacine 
Isocyclocalamin 
Isolimonic acid 16->17-lactone 
Jangomolide 
Kibalaurifenone 
Lanceotoxin A 
Lanceotoxin B 
laurinterol +  
LSM-1524 
lucibufagin C 
Lycopersiconolide 
marinobufagenin  
meproscillarin 
methyl (E)-3-[18-acetyloxy-7-(furan-3-yl)-17-hydroxy-1,8,15,15-tetramethyl-5-oxo-3,6,14-trioxapentacyclo[9.7.0.02,4.02,8.012,16]octadecan-12-yl]prop-2-enoate 
Neriantogenin 
Nomilinic acid 
O-palmitoyl-L-carnitine 
Obacunoic acid 
oleandrigenin +   
ouabagenin +  
ouabain +   
physalin F 
resibufagenin 
Rutaevin  
sarmentologenin +  
scillarenin +  
Scillipheosidin 3-[glucosyl-(1->2)-rhamnoside] 
scilliroside 
scillirosidin +  
sitoindoside IX 
spironolactone  
tanghinigenin +  
Telocinobufagin 
testololactone 
Tetrahydroaldosterone 
trilostane  
tubocapsanolide A +  
tubocapsanolide F 
viscosalactone B 
withaferin A +   
withalongolide A 
withalongolide B 
withalongolide C 
withalongolide D 
withalongolide E 
withalongolide F 
withalongolide G 
withalongolide H 
withanolide +   
withanolide D +  

Synonyms
Exact Synonyms: 3beta-hydroxy-5beta,15beta-14,15-epoxybufa-20,22-dienolide
Related Synonyms: Bufogein ;   Formula=C24H32O4 ;   InChI=1S/C24H32O4/c1-22-9-7-16(25)11-15(22)4-5-18-17(22)8-10-23(2)19(12-20-24(18,23)28-20)14-3-6-21(26)27-13-14/h3,6,13,15-20,25H,4-5,7-12H2,1-2H3/t15-,16+,17?,18?,19-,20-,22+,23-,24-/m1/s1 ;   InChIKey=ATLJNLYIJOCWJE-CWMZOUAVSA-N ;   SMILES=[C@]12(CC[C@@H](C[C@]2(CC[C@]3([C@]45[C@](CC[C@]13[H])([C@H](C[C@H]4O5)C6=COC(C=C6)=O)C)[H])[H])O)C ;   bufogenina ;   bufogenine ;   bufogeninum ;   resibufogenin ;   respigon
Xrefs: CAS:465-39-4 ;   Drug_Central:3523 ;   KEGG:C17058 ;   KEGG:D01378
Xref Mesh: MESH:C005734
Xrefs: PMID:22814872 ;   PMID:24911667 ;   PMID:25420080 ;   PMID:30029665 ;   PMID:31178234 ;   PMID:31292669 ;   PMID:31342712 ;   PMID:31737183 ;   PMID:31961485 ;   PMID:32006291

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