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Ontology Browser

Term:
spiroiminodihydantoin (CHEBI:142623)
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Parent Terms Term With Siblings Child Terms
azaspiro compound +     
hydantoin +   
mutagen +   
(2E)-dec-2-enal 
(3-chloro-1-benzothiophen-2-yl)-[2-(2-chloro-6-methylphenyl)imino-4-methylene-3-thia-1-azaspiro[4.5]decan-1-yl]methanone 
(4-tert-butylphenyl)-[2-(4-fluorophenyl)-8-methyl-3-sulfanylidene-1,4,8-triazaspiro[4.5]dec-1-en-4-yl]methanone 
(4R)-2-(4-bromo-2-fluorobenzyl)-6-fluoro-1H,2'H,5'H-spiro[isoquinoline-4,3'-pyrrolidine]-1,2',3,5'(2H)-tetrone 
(5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one 
(6R,7S,9S)-2-imino-7,9-dimethyl-1,3-diazaspiro[5.5]undecan-4-one 
(6S,7R)-2-azaspiro[5.5]undecan-7-ol 
(8aS)-7-[(6-chloronaphthalen-2-yl)sulfonyl]-8a-(methoxymethyl)-1'-pyridin-4-yltetrahydro-5H-spiro[1,3-oxazolo[3,2-a]pyrazine-2,4'-piperidin]-5-one 
(E)-4-nitrostilbene 
(S)-colchicine  
1'-[3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]hexahydro-2H-spiro[imidazo[1,2-a]pyridine-3,4'-piperidin]-2-one +  
1,1-dichloroethene  
1,2-dibromoethane  
1,2-dichloroethane  
1,2:7,8-diepoxyoctane 
1,4-dioxa-8-azaspiro[4.5]decan-8-yl(4,5,6,7-tetrahydro-1-benzothiophen-2-yl)methanone 
1,4-dioxa-8-azaspiro[4.5]decan-8-yl-(3-methyl-2-benzofuranyl)methanone 
1-(5-hydroxy-2-oxo-2,3-dihydroimidazol-4-yl)urea 
1-bromo-2-chloroethane 
1-methoxy-N-nitrosodiethylamine 
1-methylphenanthrene  
11,12-epoxy-3-methylcholanthrene 
13-desmethylspirolide C  
14-norpseurotin A 
1H-imidazo[2,1-i]purine  
2',2'-dimethyl-3-spiro[5,6,7,8a-tetrahydrothiazolo[3,2-a]pyridine-8,4'-thiane]one 
2,5-bis(aziridin-1-yl)-1,4-benzoquinone  
2,6-diaminotoluene  
2-(2,5-dichlorophenoxy)-1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-1-butanone 
2-[(1-tert-butyl-5-tetrazolyl)-thiophen-2-ylmethyl]-2-azaspiro[5.5]undecane 
2-acetamidofluorene +   
2-amino-3-cyano-5-oxo-1'-spiro[7,8-dihydro-6H-1-benzopyran-4,4'-piperidine]carboxylic acid (phenylmethyl) ester 
2-amino-6-hydroxyaminopurine 
2-nitrofluorene  
23-acetoxysoladulcidine 
3,N(4)-ethenocytosine  
4-(2-azaspiro[5.5]undecan-2-ylsulfonyl)-N-butan-2-ylbenzenesulfonamide 
4-amino-3-hydroxynaphthalene-1-sulfonic acid 
4-aminofolic acid 
4-hydroxyphenytoin  
4-methylquinoline  
4-nitroanthranilic acid +  
4-nitrophenylhydrazine 
5-bromouracil 
5-bromouridine 
5-fluorouridine  
5-formyluracil 
5-guanidinohydantoin 
6,12-dimethyldibenzo[d,d']benzo[1,2-b:4,5-b']bisthiophene 
6-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-3-ethyl-1H-pyrimidine-2,4-dione 
6-fluoro-2',5'-dioxo-2,3-dihydrospiro[chromene-4,4'-imidazolidine]-2-carboxamide +  
6-methoxyspirotryprostatin B 
6-O-methylguanine  
7-bromomethyl-12-methyltetraphene 
8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one 
8-(8-chloro-5H-pyrimido[5,4-b]indol-4-yl)-1,4-dioxa-8-azaspiro[4.5]decane 
8-(9-methyl-5H-pyrimido[5,4-b]indol-4-yl)-1,4-dioxa-8-azaspiro[4.5]decane 
8-[2-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)ethyl]-8-azaspiro[4.5]decane-7,9-dione 
8-[4-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)butyl]-8-azaspiro[4.5]decane-7,9-dione 
8-oxo-dGTP 
9-aminoacridine  
9-aminoacridine hydrochloride 
acetaldehyde +   
acridine half-mustard 
acridine half-mustard dihydrochloride 
acrylamide  
acrylonitrile +   
actinomycin D  
alkylating agent +   
allantoin +   
Annotine 
aristolochic acid +   
asperparaline A 
Azaspiracid  
azaspiracid-1 
Azaspiracid-10 
Azaspiracid-26 
Azaspiracid-3 
Azaspiracid-33 
Azaspiracid-34 
Azaspiracid-4 
Azaspiracid-5 
Azaspiracid-6 
Azaspiracid-7 
Azaspiracid-8 
Azaspiracid-9 
AZD1979 +  
Bandrowski's base  
bellidin +  
benz[a]anthracene 5,6-oxide 
benzo[b]fluoranthene  
benzo[e]pyrene  
buspirone  
buta-1,3-diene +   
caffeine +   
carboplatin  
CCT251545 
chloromethane  
cis-heme d hydroxychlorin gamma-spirolactone +  
cis-heme d hydroxychlorin gamma-spirolactone methyl ester 
cisplatin  
colibactin 
delgocitinib 
dibenz[a,h]anthracene  
dibenzo[a,l]pyrene  
diepoxybutane +   
dimethylmyleran 
Dioscorine 
epibromohydrin 
esculeogenin A 
esculeoside A 
ethyl methanesulfonate  
fagaronine 
Fawcettidine 
Fawcettimine 
fumiquinazoline C 
GM3 lactam 
hesperidin +   
hexamethylphosphoric triamide  
histrionicotoxin 
hycanthone  
hycanthone mesylate 
hydantoin-5-propionic acid 
intercalator +   
irbesartan  
iron(III) nitrilotriacetate  
isonitramine 
L-5-carboxymethylhydantoin 
ledipasvir +   
LSM-6471 
lucanthone +   
Lycoflexine 
marineosin A 
marineosin B 
Megastachine 
MeIQx +   
methoxyacetic acid  
methyl methanesulfonate  
Methyl violet 2B 
MI-63 
N(6)-hydroxyadenine 
N-[2-(trifluoromethyl)-1,3-benzodioxol-2-yl]-1,4-dioxa-8-azaspiro[4.5]decane-8-carboxamide 
N-acetoxy-2-acetamidofluorene  
N-ethyl-N-nitrosourea  
N-hydroxy-MeIQx 
N-hydroxy-PhIP  
N-methyl-N-nitrosourea  
N-methylhydantoin 
N-nitrosodiethylamine +   
N-nitrosodimethylamine  
N-nitrosomorpholine  
N-nitrosopiperidine  
N-Nitrosotomatidine 
Neopetasitenine 
oxaliplatin +   
oxirane +   
ozone  
p-N,N-bis(2-chloroethyl)amino-D-phenylalanine 
p-N,N-bis(2-chloroethyl)amino-L-phenylalanine 
p-N,N-bis(2-chloroethyl)aminophenylvaleric acid 
p-nitrobenzyl chloride  
p-p'-N,N-di(2-chloroethyl)aminophenoxyphenylalanine 
parfumine 
patulin  
phenanthridone  
phenytoin  
PhIP +   
phleomycin 
pseurotin A +  
riddelliine +   
riddelliine N-oxide 
rolapitant 
S-2-chloroethylcysteine 
SB 224289 
Serratanidine 
Serratine 
sodium azide  
sodium fluoride  
sodium hydrogensulfite  
sodium methoxyacetate 
soladulcidine 
Solamargine 
solasodine +   
Solasonine 
Solvent yellow 56 
sorbinil  
spiperone  
spiramide 
spirapril  
spiraprilat +   
spiroiminodihydantoin 
An azaspiro compound that is 1,3,6,8-tetraazaspiro[4.4]non-6-ene which is substituted by oxo groups at positions 2, 4, and 9. Both enantiomers are highly mutagenic products resulting from the oxidation of guanine and 8-oxo-7,8-dihydroguanine in DNA by reactive oxygen species.
spirolucidine 
spiropidion 
spirosolane +   
spirotetramat  
stepharine 
styrene +   
tedisamil 
tomatidine +   
Tomatidinol 
trabectedin  
trans-heme d hydroxychlorin gamma-spirolactone 
urethane  

Synonyms
Exact Synonyms: 7-amino-1,3,6,8-tetraazaspiro[4.4]non-6-ene-2,4,9-trione
Related Synonyms: Formula=C5H5N5O3 ;   InChI=1S/C5H5N5O3/c6-3-7-1(11)5(9-3)2(12)8-4(13)10-5/h(H3,6,7,9,11)(H2,8,10,12,13) ;   InChIKey=HJWQNCPSKFANJK-UHFFFAOYSA-N ;   SMILES=N1C(NC(C12N=C(NC2=O)N)=O)=O
Xrefs: PMID:15540949 ;   PMID:17915881 ;   PMID:19146379 ;   PMID:19485408 ;   PMID:20014751 ;   PMID:23360616 ;   PMID:24649945 ;   PMID:26572218 ;   PMID:26807878 ;   PMID:27074396 ;   PMID:28230976 ;   PMID:28514164 ;   PMID:28845978 ;   PMID:30592213

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