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Term:
cyclosporin A metabolite M17 (CHEBI:140154)
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Parent Terms Term With Siblings Child Terms
(+)-artemisinic alcohol +   
(+)-isoepoxydon 
(13R)-13-dihydrocarminomycin 
(1R,2S)-nortilidine +  
(1S,2R)-nortilidine +  
(24Z),26-hydroxydesmosterol 
(2E,4E)-2,4-hexadien-1-ol 
(2E,5S,6E,8E,10E)-1-aminododeca-2,6,8,10-tetraen-5-ol 
(2E,6Z)-nona-2,6-dien-1-ol 
(2S)-2-(4-\{[(1R,2S)-2-hydroxycyclopentyl]methyl\}phenyl)propanoic acid 
(5-hydroxyindol-3-yl)acetic acid  
(6-methoxy-2-naphthyl)acetic acid 
(E)-4-hydroxynon-2-en-1-ol 
(E)-4-oxonon-2-en-1-ol 
(E)-ascladiol 
(E)-non-2-en-1-ol +  
(E)-oct-2-en-1-ol 
(S)-beta-macrocarpen-15-ol +  
(Z)-4-hydroxy-3-methylbut-2-enal 
(Z)-oct-2-en-1-ol 
1,1,1,3,3,3-hexafluoropropan-2-ol  
1-(3-chlorophenyl)piperazine  
10,11-trans-dihydroxy-10,11-dihydrocarbamazepine +  
2,6-dimethylaniline +   
2-formylbenzoic acid 
2-hexen-1-ol +  
2-hydroxyibuprofen 
2-methoxyacetaminophen glucuronide 
2-methoxyacetaminophen glucuronide(1-) 
2-methoxyacetaminophen sulfate 
2-methoxyacetaminophen sulfate(1-) 
2-methylene-1,4-butanediol 
3'-hydroxy-4'-methoxydiclofenac 
3'-hydroxydiclofenac 
3,4-dihydroxymandelic acid  
3,5-dihydroxyphenylacetic acid 
3,7-dimethylocta-2,6-dien-1-ol +   
3-chlorobenzoic acid 
3-hydroxy-2,2-dimethylbutyric acid 
4',5-dihydroxydiclofenac 
4'-hydroxydiclofenac  
4-(acetylamino)-3-hydroxyphenyl hydrogen sulfate 
4-(acetylamino)-3-hydroxyphenyl sulfate 
4-(methylamino)antipyrine 
4-(trifluoromethyl)phenol 
4-acetamidoantipyrine 
4-aminoantipyrine 
4-ethoxyaniline +   
4-formylaminoantipyrine 
4-hydroxy-2,6-dimethylaniline 
4-hydroxy-6-methylaniline 
4alpha-phorbol 12,13-didecanoate 
5'-hydroxyomeprazole 
5-carboxy-2'-deoxyuridine 
5-fluorouridine 5'-monophosphate 
5-hydroxydiclofenac  
5-hydroxydiclofenac quinone imine 
6-azauridine +   
acetaminophen O-beta-D-glucosiduronic acid  
acetohydrazide +   
ACT-132577 +   
ACT-333679 +  
adefovir +   
all-trans-4-oxoretinol  
all-trans-retinol +   
alloxanthine +   
allyl alcohol +   
aripiprazole  
atenolol acid 
atenolol-desisopropyl 
azure B  
carbamazepine-10,11-epoxide  
carboxyibuprofen 
carboxyibuprofen(2-) 
ceftaroline +  
clopidogrel carboxylic acid 
cotinine N-oxide 
cyclosporin A metabolite M1 +  
cyclosporin A metabolite M10 
cyclosporin A metabolite M13 
cyclosporin A metabolite M16 +  
cyclosporin A metabolite M17 +  
A cyclosporin A derivative that is cyclosporin A in which residue 1 [(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)oct-6-enoic acid] has undergone allylic oxidation to give the corresponding primary allylic alcohol. It specifically inhibits growth of renal cells in culture.
cyclosporin A metabolite M18 +  
cyclosporin A metabolite M1A 
cyclosporin A metabolite M1cAL 
cyclosporin A metabolite M21 +  
cyclosporin A metabolite M25 
cyclosporin A metabolite M26 
cyclosporin A metabolite M8 +  
cyclosporin A metabolite M9 
D617 
desmethyl loperamide 
desmethyldoxepin +  
desmethylnaproxen  
desmethylnaproxen sulfate 
desmethylnaproxen(1-) 
desmethylranitidine 
diclofenac beta-D-glucosiduronic acid 
didesethylflurazepam 
dioxoaminopyrine 
doxorubicinol 
ethisterone 
eucommiol 
fenofibric acid 
flavuxanthin 
ganoderol B  
glycinexylidide +  
hydroxyalbendazole 
hydroxyfenbendazole 
imidaprilat  
indometacin +   
ixazomib +   
mevinolinic acid 
monoethylglycinexylidide +   
N,N-didesmethylvenlafaxine 
N,O-didesmethylvenlafaxine 
N-acetylsulfamethoxazole 
N-desmethylvenlafaxine 
nitrazepam +   
nitrososulfadiazine 
nitrososulfapyridine 
nonaflavuxanthin 
norfentanyl 
nortriptyline  
norverapamil  
O-desmethylvenlafaxine 
omega-hydroxy-beta-dihydromenaquinone-9 
oxidopamine  
oxyphenbutazone +   
paliperidone 
paracetamol sulfate +   
pedilstatin 
perindoprilat 
phyllostine 
prednisolone +   
procainamide 4-hydroxylamine 
proglumide +  
psilocin +  
pyrazine-2-carboxylic acid  
pyridine N-oxide +   
rac-nortilidine 
ramiprilat  
ranitidine N-oxide 
ranitidine-S-oxide 
ritalinic acid  
S-(5-acetamido-2-hydroxyphenyl)-N-acetyl-L-cysteinate 
S-(5-acetamido-2-hydroxyphenyl)-N-acetyl-L-cysteine 
SN-38 +   
spiraprilat +   
sulfadiazine hydroxylamine 
sulfapyridine hydroxylamine 
tedizolid 
tenofovir (anhydrous) +   
teriflunomide  
theophylline +   
trandolaprilat 
uridine +   
WR-1065  
zofenoprilat 

Synonyms
Exact Synonyms: (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-33-[(1R,2R,4E)-1,6-dihydroxy-2-methylhex-4-en-1-yl]-30-ethyl-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
Related Synonyms: 6-[(2S,3R,4R,6E)-3,8-dihydroxy-4-methyl-2-(methylamino)-6-octenoic acid]cyclosporin ;   AM1 ;   CsA M17 ;   Formula=C62H111N11O13 ;   InChI=1S/C62H111N11O13/c1-24-43-58(82)67(17)33-48(75)68(18)44(29-34(2)3)55(79)66-49(38(10)11)61(85)69(19)45(30-35(4)5)54(78)63-41(15)53(77)64-42(16)57(81)70(20)46(31-36(6)7)59(83)71(21)47(32-37(8)9)60(84)72(22)50(39(12)13)62(86)73(23)51(56(80)65-43)52(76)40(14)27-25-26-28-74/h25-26,34-47,49-52,74,76H,24,27-33H2,1-23H3,(H,63,78)(H,64,77)(H,65,80)(H,66,79)/b26-25+/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50+,51+,52-/m1/s1 ;   InChIKey=ZPZHKIOMBYYVRD-WRDPQARASA-N ;   M17 ;   OL-17 ;   SMILES=[C@H]1(N(C([C@@H](N(C([C@@H](N(C)C([C@@H](N(C([C@H](NC([C@@H](NC([C@@H](N(C([C@@H](NC([C@@H](N(C)C(CN(C([C@@H](NC1=O)CC)=O)C)=O)CC(C)C)=O)C(C)C)=O)C)CC(C)C)=O)C)=O)C)=O)C)CC(C)C)=O)CC(C)C)=O)C)C(C)C)=O)C)[C@@H]([C@@H](C/C=C/CO)C)O ;   cyclosporin metabolite AM1 ;   cyclosporin metabolite M17 ;   cyclosporine A metabolite M17 ;   cyclosporine metabolite M17
Xrefs: CAS:89270-28-0 "ChemIDplus" ;   PMID:17908922 "Europe PMC" ;   PMID:1834063 "Europe PMC" ;   PMID:1943052 "Europe PMC" ;   PMID:2389436 "Europe PMC" ;   PMID:2642763 "Europe PMC" ;   PMID:2784905 "Europe PMC" ;   PMID:2948307 "Europe PMC" ;   PMID:2950629 "Europe PMC" ;   PMID:7914868 "Europe PMC" ;   PMID:8234147 "Europe PMC" ;   PMID:8349948 "Europe PMC" ;   PMID:8400080 "Europe PMC" ;   PMID:8894806 "Europe PMC" ;   PMID:8971957 "Europe PMC" ;   PMID:9106068 "Europe PMC" ;   PMID:9180163 "Europe PMC" ;   PMID:9555934 "Europe PMC"

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.