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Ontology Browser

Term:
D-myo-Ins(1,4,5)P3 hexakis(butyryloxymethyl) ester (CHEBI:138527)
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Parent Terms Term With Siblings Child Terms
1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate +  
D-myo-Ins(1,4,5)P3 hexakis(butyryloxymethyl) ester 
A phosphatidylinositol trisphosphate that is 1D-myo-inositol 1,4,5-trisphosphate in which all all six phosphate hydrogens have been replaced by butyryloxymethyl groups. It is a cell-permeant analogue of inositol 1,4,5-trisphosphate and an agonist of the inositol 1,4,5-trisphosphate receptor.

Synonyms
Exact Synonyms: [(1R,2R,3S,4R,5R,6S)-3,5,6-trihydroxycyclohexane-1,2,4-triyl]tris[oxyphosphorylbis(oxymethylene)] hexabutanoate ;   [(1R,2R,3S,4R,5R,6S)-3,5,6-trihydroxycyclohexane-1,2,4-triyl]tris[oxyphosphorylbis(oxymethylene)] hexabutyrate
Related Synonyms: (-)-1D-myo-inositol 1,4,5-triphosphate hexakis(butyryloxymethyl) ester ;   D-myo-Ins(1,4,5)P3 hexakis(butanoyloxymethyl) ester ;   Formula=C36H63O27P3 ;   IP3/BM ;   InChI=1S/C36H63O27P3/c1-7-13-25(37)49-19-55-64(46,56-20-50-26(38)14-8-2)61-34-31(43)32(44)35(62-65(47,57-21-51-27(39)15-9-3)58-22-52-28(40)16-10-4)36(33(34)45)63-66(48,59-23-53-29(41)17-11-5)60-24-54-30(42)18-12-6/h31-36,43-45H,7-24H2,1-6H3/t31-,32+,33+,34-,35-,36-/m1/s1 ;   InChIKey=PVEVFIAVCISJSO-FOJCDXFYSA-N ;   SMILES=[C@@H]1([C@@H]([C@@H](O)[C@H]([C@H]([C@@H]1O)OP(=O)(OCOC(=O)CCC)OCOC(=O)CCC)O)OP(=O)(OCOC(=O)CCC)OCOC(=O)CCC)OP(=O)(OCOC(=O)CCC)OCOC(=O)CCC
Xrefs: CAS:209479-81-2 "SUBMITTER" ;   PMID:12522076 "Europe PMC" ;   PMID:28390800 "Europe PMC" ;   Reaxys:10757630 "Reaxys"

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.