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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
icosanoid +     
(5Z,9E,12S,14Z)-8,11,12,20-tetrahydroxyicosa-5,9,14-trienoic acid 
(6E,8Z,10E,12S,14Z)-12-hydroxy-5-oxoicosatetraenoic acid 
(6E,8Z,11Z,13E,15S)-15-hydroxy-5-oxoicosatetraenoic acid 
(6E,8Z,11Z,14Z,17Z)-5-oxoicosapentaenoic acid 
(7R)-hydroxy-(5S,6S)-epoxy-(8Z,11Z,14Z)-icosatrienoic acid 
11R-HEDE 
11S-HEDE 
12(S)-HPE(5,8,10)TrE 
12-HPE(8,10,14)TrE +  
12-Keto-tetrahydro-LTB4 
13,14-dihydro-15-oxolipoxin A4 
13,14-dihydrolipoxin A4 
14-carboxy-15,16,17,18,19,20-hexanor-leukotriene E3 
15R-HEDE 
16-carboxy-17,18,19,20-tetranor-leukotriene E3 
16-carboxy-Delta(13)-17,18,19,20-tetranor-leukotriene E4 +  
18-carboxy-19,20-dinor-leukotriene E4 
5(S),6(S)-epoxy-18(R)-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoic acid 
5(S),6(S)-epoxy-18-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoic acid +  
5,20-diHEPE 
5,8,11-icosatriynoic acid 
5-hydroperoxy-15-HETE +  
bis(hydroperoxy)icosatetraenoic acid +  
DG(14:0/20:2(11Z,14Z)/0:0) 
DG(14:0/20:3(5Z,8Z,11Z)/0:0) 
DG(14:0/20:3(8Z,11Z,14Z)/0:0) 
DG(14:0/20:4(5Z,8Z,11Z,14Z)/0:0) 
DG(14:0/20:4(8Z,11Z,14Z,17Z)/0:0) 
DG(14:1(9Z)/20:2(11Z,14Z)/0:0) 
DG(14:1(9Z)/20:3(5Z,8Z,11Z)/0:0) 
DG(14:1(9Z)/20:3(8Z,11Z,14Z)/0:0) 
DG(18:0/0:0/20:4n3) 
DG(18:0/0:0/20:4n6) 
DG(18:1n7/0:0/20:3n6) 
DG(18:1n7/0:0/20:3n9) 
DG(18:1n9/0:0/20:3n6) 
DG(18:1n9/0:0/20:3n9) 
DHET +  
dihydroxyicosatetraenoic acid +  
EET +   
EpETE +  
HETE +   
HPETE +   
hydroperoxy(epoxy)icosatrienoic acid +  
hydroperoxy(hydroxy)icosapentaenoic acid +  
hydroperoxy(hydroxy)icosatetraenoic acid +  
hydroperoxyicosapentaenoic acid +  
hydroperoxyicosatrienoic acid +  
icosenoic acid +  
isoprostane +   
Any icosanoid with a prostaglandin-like structure formed in vivo by non-enzymatic free radical-catalysed reactions involving peroxidation of essential fatty acids (mainly arachidonic acid but also other fatty acids with 3 or more double bonds). Isoprostanes are abundant in tissues and fluids and have immunomodulating activity. Their concentration is dependent on the amount of oxidative stress and may be upregulated in certain diseases such as cancer, cardiovascular and neurological disorders.
leukotriene +   
levuglandin +  
nonclassic icosanoid +   
prostanoid +   
 F2-isoprostane +   

Synonyms
Related Synonyms: IsoPs ;   isoprostanes
Xrefs: PMID:10385607 ;   PMID:12088281 ;   PMID:12751772 ;   PMID:15037155 ;   PMID:15037162 ;   PMID:15650410 ;   PMID:15780831 ;   PMID:16382569 ;   PMID:18030056 ;   PMID:18285331 ;   PMID:20951733 ;   PMID:21848345 ;   Wikipedia:Isoprostane

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