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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
(+)-(1S,2S)-norcoronamic acid 
(1,2,3-trimethyl-2-cyclopropen-1-yl)benzene 
(1-methylbutyl)cyclopentane 
(2,3-diphenylcyclopropyl)methyl phenyl sulfoxide 
(22E)-24,26-cyclo-19-norcholesta-1,3,5(10),22-tetraen-3-ol 
(2R,3S,2'R)-nadolol +   
(2S,4R)-hypoglycin B +  
(2S,4S)-hypoglycin B +  
(3-chloro-1-benzothiophen-2-yl)-[2-(2-chloro-6-methylphenyl)imino-4-methylene-3-thia-1-azaspiro[4.5]decan-1-yl]methanone 
(4-tert-butylphenyl)-[2-(4-fluorophenyl)-8-methyl-3-sulfanylidene-1,4,8-triazaspiro[4.5]dec-1-en-4-yl]methanone 
(4R)-2-(4-bromo-2-fluorobenzyl)-6-fluoro-1H,2'H,5'H-spiro[isoquinoline-4,3'-pyrrolidine]-1,2',3,5'(2H)-tetrone 
(5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one 
(6R,7S,9S)-2-imino-7,9-dimethyl-1,3-diazaspiro[5.5]undecan-4-one 
(6S,7R)-2-azaspiro[5.5]undecan-7-ol 
(8aS)-7-[(6-chloronaphthalen-2-yl)sulfonyl]-8a-(methoxymethyl)-1'-pyridin-4-yltetrahydro-5H-spiro[1,3-oxazolo[3,2-a]pyrazine-2,4'-piperidin]-5-one 
(R,R)-chrysanthemal +   
(S)-timolol (anhydrous) +   
(S)-timolol hemihydrate 
(S)-timolol maleate 
1,4-dioxa-8-azaspiro[4.5]decan-8-yl(4,5,6,7-tetrahydro-1-benzothiophen-2-yl)methanone 
1,4-dioxa-8-azaspiro[4.5]decan-8-yl-(3-methyl-2-benzofuranyl)methanone 
1,5-diazabicyclo[3.2.2]nonane 
1,5-diazabicyclo[3.3.1]nonane 
1-(1-phenylcyclopentyl)methylamine 
1-(2-methylenecyclopropyl)ethanone 
1-bromo-4-cyclopropylbenzene 
1-cyclopentylethanol 
1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-N-[4-(5-thioxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)phenyl]-1,4-dihydroquinoline-3-carboxamide 
1-heptyl-2-octylcyclopentane +  
1-methylcyclopentanecarboxylic acid 
1-methylidene-2-(pent-4-en-1-yl)cyclopropane 
12-hydroxynevirapine 
13-desmethylspirolide C  
14-norpseurotin A 
2',2'-dimethyl-3-spiro[5,6,7,8a-tetrahydrothiazolo[3,2-a]pyridine-8,4'-thiane]one 
2-(2,5-dichlorophenoxy)-1-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-1-butanone 
2-(3,5-dichlorophenylcarbamoyl)-1,2-dimethylcyclopropane-1-carboxylic acid 
2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol +   
2-(4-hydroxyphenyl)ethanol +   
2-[(1-tert-butyl-5-tetrazolyl)-thiophen-2-ylmethyl]-2-azaspiro[5.5]undecane 
2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-1,2,4-triazole-3-thione +   
2-amino-3-(2-methylenecyclopropyl)propanoic acid +  
2-amino-3-cyano-5-oxo-1'-spiro[7,8-dihydro-6H-1-benzopyran-4,4'-piperidine]carboxylic acid (phenylmethyl) ester 
2-cyano-3-cyclopropyl-1-(2-mesyl-4-trifluoromethylphenyl)propan-1,3-dione 
2-cyclopentyl-4-[5-(3-methylphenyl)furo[2,3-b]pyridin-3-yl]benzoic acid 
2-hydroxy-3-(2-methylidenecyclopropyl)butanedioic acid 
2-phenylcyclopropan-1-amine +   
23-acetoxysoladulcidine 
26,27-dehydrozymosterol 
3'''-O-acetyldigitoxin 
3-bromo-N-\{2-bromo-4-chloro-6-[(1-cyclopropylethyl)carbamoyl]phenyl\}-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide +  
3beta-hydroxy-9beta-9,19-cyclolanost-24-en-28-oic acid 
4-(2-azaspiro[5.5]undecan-2-ylsulfonyl)-N-butan-2-ylbenzenesulfonamide 
4-aminopyridine +   
4-aminopyridine-3-methanol 
5-[(2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl]pyrimidine-2,4-diamine +  
5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate +  
5alpha,8alpha-epidioxysterol 
6-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-3-ethyl-1H-pyrimidine-2,4-dione 
6-fluoro-2',5'-dioxo-2,3-dihydrospiro[chromene-4,4'-imidazolidine]-2-carboxamide +  
6-methoxyspirotryprostatin B 
8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one 
8-(8-chloro-5H-pyrimido[5,4-b]indol-4-yl)-1,4-dioxa-8-azaspiro[4.5]decane 
8-(9-methyl-5H-pyrimido[5,4-b]indol-4-yl)-1,4-dioxa-8-azaspiro[4.5]decane 
8-[2-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)ethyl]-8-azaspiro[4.5]decane-7,9-dione 
8-[4-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)butyl]-8-azaspiro[4.5]decane-7,9-dione 
9-cyclopentyl-N(8)-(2-fluorophenyl)-N(2)-(4-methoxyphenyl)-9H-purine-2,8-diamine 
acebutolol  
acebutolol hydrochloride 
acetylstrophanthidin 
adenosine +   
alprenolol +   
aminocyclopyrachlor +  
Annotine 
asperparaline A 
atenolol +   
atropine +   
Azaspiracid  
azaspiracid-1 
Azaspiracid-10 
Azaspiracid-26 
Azaspiracid-3 
Azaspiracid-33 
Azaspiracid-34 
Azaspiracid-4 
Azaspiracid-5 
Azaspiracid-6 
Azaspiracid-7 
Azaspiracid-8 
Azaspiracid-9 
AZD1979 +  
barium chloride +   
barium chloride dihydrate 
BAY 41-2272 
BAY 60-6583  
beclomethasone dipropionate 
bepridil +   
berberine  
beta-(methylenecyclopropyl)pyruvic acid 
bevantolol +   
bevantolol hydrochloride +  
bisoprolol +   
bretylium +   
bretylium tosylate  
brevipolide A 
brevipolide B 
buspirone  
calcipotriol +   
candelalide A 
candelalide B 
candelalide C 
carteolol  
carteolol hydrochloride 
CCT251545 
CD532 
chrysanthemic acid +   
chrysanthemol +   
cinalukast 
ciprofibrate  
cis-heme d hydroxychlorin gamma-spirolactone +  
cis-heme d hydroxychlorin gamma-spirolactone methyl ester 
clidinium +   
clidinium bromide 
colibactin 
coprine 
cyclanilide 
cyclopentane +  
cyclopentanols +   
cyclopropane +  
cyclopropanecarboxylate ester +   
cyclopropanecarboxylic acid +   
cyclopyrimorate 
cyprodinil  
cyproflanilide 
cyprosulfamide 
deslanoside 
devapamil 
digoxin +   
Dioscorine 
disopyramide +   
dofetilide  
dronedarone  
E-3810 free base 
efavirenz  
encainide +  
encainide hydrochloride 
enprofylline +  
enrofloxacin  
ent-diltiazem 
ent-diltiazem hydrochloride 
ent-diltiazem(1+) +  
epsilon-metofluthrin 
epsilon-momfluorothrin 
esculeogenin A 
esculeoside A 
esmolol +   
esmolol hydrochloride 
ethyl 1-allylcyclopropanecarboxylate 
ethyl L-methioninate 
ethylisopropylamiloride  
Fawcettidine 
Fawcettimine 
felodipine  
finafloxacin 
firocoxib 
flecainide  
flecainide acetate 
flucycloxuron +  
FR171456 
fumiquinazoline C 
garenoxacin 
glyburide  
GM3 lactam 
grazoprevir +  
heptafluthrin 
histrionicotoxin 
imiprothrin 
irbesartan  
irgarol 1051 
isonitramine 
isoxaflutole 
jawsamycin 
kappa-bifenthrin 
L-alpha-(methylidenecyclopropyl)glycine 
ledipasvir +   
lenvatinib 
lesinurad 
levosimendan 
lidocaine +   
lidocaine hydrochloride +  
lidocaine hydrochloride monohydrate 
losartan +   
LSM-6471 
lumacaftor +   
Lycoflexine 
magnesium sulfate +   
marineosin A 
marineosin B 
Megastachine 
methyl cyclopropanecarboxylate 
metipranolol  
metipranolol hydrochloride 
mexiletine +   
mexiletine hydrochloride 
MI-63 
MLI-2 
montelukast +   
moricizine +   
moricizine hydrochloride 
moxifloxacin  
N-(2-[(2-aminoethyl)(methyl)amino]-5-\{[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino\}phenyl)acetamide 
N-([biphenyl]-2-yl)-3-cyclopentylpropanamide 
N-[2-(trifluoromethyl)-1,3-benzodioxol-2-yl]-1,4-dioxa-8-azaspiro[4.5]decane-8-carboxamide 
N-\{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl\}-3-(difluoromethyl)-1-methyl-1pyrazole-4-carboxamide +  
N-\{3-[(5-cyclopropyl-2-\{[3-methyl-1-(2,2,2-trifluoroethyl)-1H-pyrazol-4-yl]amino\}pyrimidin-4-yl)amino]propyl\}cyclobutanecarboxamide 
N-acetylprocainamide 
N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide 
N-cyclopropyl-3-\{4-[(cyclopropylmethyl)carbamoyl]phenyl\}-4-methylbenzamide 
N-cyclopropyl-3-\{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydropyrazolo[3,4-b]pyridin-4-yl]amino\}-4-methylbenzamide 
N-cyclopropyl-4-[4-(3,4-dichlorophenyl)-2-(1-methylpiperidin-4-yl)-1-propylimidazol-5-yl]pyrimidin-2-amine 
nadolol  
nalanthalide 
naltrexone  
nevirapine +   
norverapamil  
olaparib  
ouabain  
palbociclib  
parfumine 
paritaprevir +  
permethrin +   
PHA-533533 
pilsicainide 
pitavastatin  
PP121 
practolol  
prallethrin  
procainamide +   
procainamide hydrochloride 
propafenone  
propafenone hydrochloride 
propranolol +   
pseurotin A +  
quinidine +   
ranolazine  
roflumilast  
rolapitant 
SB 224289 
Serratanidine 
Serratine 
SGC-CK2-1 
Solamargine 
solasodine  
Solasonine 
sorbinil  
sotalol  
sotalol hydrochloride 
spiperone  
spiramide 
spirapril  
spiraprilat +   
spiroiminodihydantoin 
spirolucidine 
spirosolane +   
spirotetramat  
stepharine 
tasimelteon 
tedisamil 
A member of the class of diazabicyclononanes that is (1s,5s)-3,7-diazaspiro[bicyclo[3.3.1]nonane-9,1'-cyclopentane] in which the hydrogens at positions 3 and 7 are replaced by cyclopropylmethyl groups. It is a potassium channel blocker and an antiarrhythmic agent currently currently in development for the treatment of atrial fibrillation.
telaprevir  
tert-butyl N-\{1-[(1S)-1-\{[(1R,2S)-1-(benzylcarbamoyl)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl]carbamoyl\}-2-cyclopropylethyl]-2-oxopyridin-3-yl\}carbamate 
tetraethylammonium chloride 
tetrapropylammonium bromide 
tocainide 
tolazamide 
tolbutamide  
tomatidine +   
trabectedin  
tralomethrin  
trametinib +   
trans-heme d hydroxychlorin gamma-spirolactone 
trans-piceid  
transfluthrin  
trinexapac +  
trinexapac-ethyl 
verapamil  
verruculogen +  

Synonyms
Exact Synonyms: (1s,5s)-3,7-bis(cyclopropylmethyl)-3,7-diazaspiro[bicyclo[3.3.1]nonane-9,1'-cyclopentane]
Related Synonyms: Formula=C19H32N2 ;   InChI=1S/C19H32N2/c1-2-8-19(7-1)17-11-20(9-15-3-4-15)12-18(19)14-21(13-17)10-16-5-6-16/h15-18H,1-14H2/t17-,18+ ;   InChIKey=CTIRHWCPXYGDGF-HDICACEKSA-N ;   KC-8857 ;   KC8857 ;   Pulzium ;   SMILES=[H][C@]12CN(CC3CC3)C[C@]([H])(CN(CC3CC3)C1)C21CCCC1 ;   tedisamilum
Xrefs: CAS:90961-53-8 ;   DrugBank:DB06200 ;   Drug_Central:4655 ;   KEGG:D06652 ;   PMID:10566055 ;   PMID:10707827 ;   PMID:11116286 ;   PMID:11527020 ;   PMID:14996649 ;   PMID:15466442 ;   PMID:15579009 ;   PMID:1570027 ;   PMID:1769368 ;   PMID:19153714 ;   PMID:19299533 ;   PMID:19604120 ;   PMID:2017153 ;   PMID:2043919 ;   PMID:2721548 ;   PMID:2780585 ;   PMID:8480574 ;   PMID:8730401 ;   PMID:8882624 ;   PMID:9464363 ;   PMID:9831899 ;   Wikipedia:Tedisamil

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.