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Term:
11a-hydroxytetracycline (CHEBI:134017)
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Parent Terms Term With Siblings Child Terms
(+)-(12E,2S,3S,4R,5R,6R,9S,11S,15R)-3-benzoyloxy-5,6-epoxylathyr-12-en-15-ol-14-one 
(+)-(12E,2S,3S,4R,5R,6R,9S,11S,15R)-3-cinnamoyloxy-5,6-epoxylathyr-12-en-15-ol-14-one 
(+)-(5E,12E,2S,3S,4S,9S,11S,15R)-3-cinnamoyloxylathyra-5,12-dien-15-ol-14-one 
(+)-cis-isohumulone 
(+)-DCA-CC 
(+)-DCA-CL 
(-)-(12E,2S,3S,4R,5R,6R,9S,11S,15R)-3-acetoxy-5,6-epoxylathyr-12-en-15-ol-14-one 
(-)-(6Z,12E,2S,3S,4R,5R,9S,11S,15R)-3-cinnamoyloxylathyra-6,12-diene-5,15-diol-14-one 
(-)-(6Z,12E,2S,3S,4R,5R,9S,11S,15R)-5-cinnamoyloxylathyra-6,12-diene-3,15-diol-14-one 
(-)-DCA-CC 
(-)-DCA-CL 
(-)-microdiplodiasolol 
(16alpha,20R,24R)-24N,25-carbamoyloxy-2,16,20-trihydroxycucurbita-1,5-diene-3,11,22-trione 2-O-beta-D-glucopyranoside 
(16alpha,20R,24S)-2,16,20,25-tetrahydroxy-24-methoxycucurbita-1,5-diene-3,11,22-trione 2-O-beta-D-glucopyranoside 
(1S)-1,23,25-trihydroxy-24-oxocalciol 
(1S)-1,25-dihydroxy-24-oxocalciol 
(22E,24R)-3beta,5alpha,9alpha-trihydroxyergosta-7,22-dien-6-one 
(22E,24R)-3beta,5alpha-dihydroxyergosta-7,22-dien-6-one 
(2R,3S)-glycosmisic acid 
(2Z,4Z)-5-carboxypenta-2,4-dienoate 
(3S,5R,10R,12S,14S,15R,16R)-3,5,10,14,15-pentahydroxy-12,16-dimethylicosan-2-one 
(4aS,5aR,12aS)-10,12a-dihydroxy-1,3,11,12-tetraoxo-4,4a,5,5a,6,11a-hexahydrotetracene-2-carboxamide 
(4R,12aR)-4,7-bis(dimethylamino)-10,12a-dihydroxy-1,3,11,12-tetraoxo-4,4a,5,5a,6,11a-hexahydrotetracene-2-carboxamide 
(4S,4aR,5S,12aS)-7-chloro-4-(dimethylamino)-5,10,12a-trihydroxy-6-methylene-1,3,11,12-tetraoxo-4a,5,5a,11a-tetrahydro-4H-tetracene-2-carboxamide 
(4S,4aS,5aR,12aS)-9-[[2-(tert-butylamino)-1-oxoethyl]amino]-4,7-bis(dimethylamino)-10,12a-dihydroxy-1,3,11,12-tetraoxo-4,4a,5,5a,6,11a-hexahydrotetracene-2-carboxamide 
(4S,4aS,5aR,6S,12aS)-7-chloro-4-(dimethylamino)-6,10,12a-trihydroxy-6-methyl-1,3,11,12-tetraoxo-4a,5,5a,11a-tetrahydro-4H-tetracene-2-carboxamide 
(4S,4aS,6S,12aS)-7-chloro-4-(dimethylamino)-6,10,12a-trihydroxy-6-methyl-1,3,11,12-tetraoxo-4a,5,5a,11a-tetrahydro-4H-tetracene-2-carboxamide 
(4Z,8Z)-4,8-dimethyl-12-oxotrideca-4,8-dienal 
(R)-2-hydroxyglutaryl-CoA 
(R)-blebbistatin 
(S)-2-acetyl-2-hydroxybutanoic acid 
(S)-blebbistatin 
1,2,4-butanetriol 
1,2-dihydronaphthalene-1,2-diol +   
1,3,7-trimethyl-5-hydroxyisouric acid 
1-hydroxy-2-naphthoate 
1-hydroxy-2-naphthoic acid  
1-hydroxylimonen-2-one +  
1-naphthoate 
1-naphthoic acid +  
1-O-demethyl-6-deoxydoxorubicin 
10-hydroxyoctadecanoic acid 
11-deoxycortisol  
11a-hydroxy-7-iodotetracycline zwitterion 
11a-hydroxychlortetracycline zwitterion 
11a-hydroxytetracycline 
A member of the class of tetracyclines obtained by selective hydroxylation at position 11a of tetracycline.
11a-hydroxytigecycline(1+) 
11beta,17alpha,21-trihydroxypregnenolone 
11beta-hydroxytestosterone 
12-dehydrotetracycline 
12-deoxyphorbol 20-acetate 13-(2-methylbutanoate) 
12-deoxyphorbol-13-(3E,5E-decadienoate) 
12-hydroxyoctadecanoic acid +  
12-methylpentadecanoic acid 
16-hydroxyphorbol 13-decanoate 12-palmitate 
16alpha,17alpha-dihydroxypregnenolone 
17,21-dihydroxy-5beta-pregnane-3,11,20-trione  
17-epi-17-hydroxyazadiradione 
17-hydroxyazadiradione 
17-hydroxypregnenolone 3-sulfate 
17-hydroxyprogesterone 3-O-(carboxymethyl)oxime 
17alpha,21-dihydroxypregnenolone 
17alpha-hydroxypregn-5-ene-3,20-dione 
17alpha-hydroxypregnenolone +   
17alpha-hydroxyprogesterone  
2'-hydroxyrifampicin 
2'-hydroxyrifampicin(1-) 
2,4-dihydroxy-5-methyl-6-oxo-2,4-hexadienoate 
2,4-dihydroxy-5-methyl-6-oxo-2,4-hexadienoic acid 
2,4-dinitrophenol +   
2,4-dinitrophenol(1-) 
2,5-dichloro-2,5-cyclohexadiene-1,4-diol 
2,5-dichlorohydroquinone 
2,6-dichlorobenzoic acid +  
2,6-dimethylheptanoic acid 
2-acetyllactic acid +  
2-aminophenylglyoxylic acid 
2-benzylsuccinate(2-) 
2-benzylsuccinic acid +  
2-dehydro-3,6-dideoxy-6-sulfo-D-gluconic acid 
2-ethylhexanal 
2-formylbenzoate 
2-formylbenzoic acid 
2-furoate 
2-furoic acid +   
2-hydroxy-2-methylpropanal 
2-hydroxy-6-oxo-2,4-heptadienoate +  
2-hydroxy-6-oxo-2,4-heptadienoic acid +  
2-hydroxy-7,8-dihydropteroic acid 
2-methylpropane-1,2-diol 
21-acetoxy-11beta,17-dihydroxy-6alpha-methylpregn-4-ene-3,20-dione 
21-dehydrocortisol  
21-dehydrocortisone 
23(S),25-dihydroxy-24-oxovitamin D3 
23,24-dihydrocucurbitacin +  
23,24-dihydrocucurbitacin B 
23,24-dihydrocucurbitacin D 
23,24-dihydrocucurbitacin E 
25-hydroxy-24-oxocalciol 
3'-deamino-3'-(3-cyanomorpholin-4-yl)doxorubicin  
3'-deoxysappanone B 
3,4-dichlorocatechol 
3,5-dibromocatechol 
3,6-dichloropyridine-2,5-diol 
3,6-dihydroxypyridine-2,5-dione 
3-(2-hydroxyphenyl)propanoate 
3-(2-hydroxyphenyl)propanoic acid 
3-bromo-4-hydroxybenzoic acid 
3-farnesyl-3-hydroxy-2-methyl-1-oxo-1lambda(5)-quinolin-4-one 
3-fluorocatechol 
3-hexanone 
3-hydroxy-2-methyl-3-phytyl-2,3-dihydro-1,4-naphthoquinone 
3-hydroxy-3-methyl-2-oxobutanoic acid 
3-hydroxy-3-methyl-2-oxopentanoic acid +  
3-linalylflaviolin 
3-linalylflaviolin-2-olate 
3-methylcatechol +   
3-methylsalicylic acid 
3-oxoadipic acid +  
4',5'-dihydro-11,5'-dihydroxy-4'-methoxytephrosin 
4'-deoxy-4'-iododoxorubicin 
4'-epidoxorubicin  
4'-oxolividamine 
4,5-dihydrocortisone +   
4-(dimethylamino)-5,10,12a-trihydroxy-6-methyl-1,3,11,12-tetraoxo-4,4a,5,5a,6,11a-hexahydrotetracene-2-carboxamide 
4-(dimethylamino)-6,10,12a-trihydroxy-6-methyl-1,3,11,12-tetraoxo-4a,5,5a,11a-tetrahydro-4H-tetracene-2-carboxamide 
4-amino-4-de(dimethylamino)anhydrotetracycline 
4-amino-5-formamidomethyl-2-methylpyrimidine 
4-Aminoanhydrochlortetracycline 
4-chlorobenzoate 
4-chlorobenzoic acid +  
4-chlorocatechol  
4-de(dimethylamino)-4-oxoanhydrotetracycline 
4-Dedimethylamine-4-oxo-anhydro-7-Cl-tetracycline 
4-fluorobenzoate 
4-fluorobenzoic acid +   
4-hydroxy-2-methyl-3-oxo-[(2E,6E)-farnesyl]-3,4-dihydroquinoline-1-oxide 
4-hydroxychlorothalonil 
4-methyl-5-nitrocatechol 
4-nitroaniline +   
4-pregnen-20,21-diol-3-one 
4alpha-phorbol 12,13-didecanoate 
5,10-dihydrophenazine 
5-chloromuconolactone 
5-chloromuconolactone(1-) 
5-hydroxymethyl-2-furoic acid 
5-oxohexanoic acid 
5a,11a-Dehydrochlortetracycline 
5a,11a-dehydrooxytetracycline 
5beta-dihydrocortisol 
6-chloropyridine-2,3,5-triol 
6-deoxy-6-sulfo-D-gluconic acid 
6-deoxy-6-sulfoglucono-1,5-lactone 
6-hydroxy-N-methylmyosmine 
6-hydroxy-N-methylmyosmine(1+) 
6-hydroxyhexanoic acid +  
6-methylprednisolone +   
6alpha-fluoro-17-hydroxycorticosterone 21-acetate 
6alpha-methylprednisolone +   
6beta,16alpha,17alpha-trihydroxyprogesterone 
6beta-hydroxycortisol  
6beta-hydroxycortisone 
7-chloro-4-(dimethylamino)-6,10,12a-trihydroxy-1,3,11,12-tetraoxo-4,4a,5,5a,6,11a-hexahydrotetracene-2-carboxamide 
8-demethyl-8-(2,3,4-O-trimethyl-alpha-L-rhamnosyl)tetracenomycin C 
8-demethyl-8-(2,3-O-dimethyl-alpha-L-rhamnosyl)tetracenomycin C 
8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)tetracenomycin C 
8-demethyl-8-(alpha-L-rhamnosyl)tetracenomycin C 
8-demethyltetracenomycin C 
9-fluoro-11beta,17,21-trihydroxy-2alpha-methylpregn-4-ene-3,20-dione 21-acetate 
9E,11E-octadecadienoic acid +   
[(S)-3-oxocyclohexyl]acetic acid 
a tetracycline zwittterion +  
alclometasone 
algestone +  
alpha-D-GalpA-(1->4)-alpha-D-GalpA 
alpha-D-GalpA-(1->4)-alpha-D-GalpA-(1->4)-alpha-D-GalpA 
alpha-D-GalpA-(1->4)-alpha-D-GalpA-(1->4)-alpha-D-GalpA-(1->4)-alpha-D-GalpA 
alpha-pinene oxide 
Anhydrochlortetracycline 
anhydrotetracycline +  
anhydrotetracycline zwitterion 
asperfuranone 
avilamycin A 
avilamycin A precursor 
azanigerone E 
beclomethasone +   
berkeleydione 
berkeleyone A 
berkeleyone B 
berkeleyone C 
berkeleytrione 
betamethasone +   
betamethasone acetate 
betamethasone phosphate 
betamethasone sodium phosphate 
blebbistatin +   
BMS-192548 
bruceolline M 
calotropone 
caribenol B 
carminomycin +  
caudatin-3-O-beta-cymaropyranoside 
cellotriose +  
chermesinone A 
chlortetracycline  
cis,cis-muconate +  
cis,cis-muconic acid +  
clobetasol +   
clomocycline 
comazaphilone D 
comazaphilone E 
comazaphilone F 
cortancyl 
cortisol +   
cortisol 21-acetate 
cortisol 21-sulfate 
cortisol phosphate 
cortisone +   
cortistatin D 
cucurbitacin B +   
cucurbitacin D 
cucurbitacin E +   
cucurbitacin E 2-O-beta-D-glucopyranoside 
cucurbitacin I +   
cucurbitacin I 2-O-beta-D-glucopyranoside 
cucurbitacin J +  
cucurbitacin J 2-O-beta-D-glucopyranoside 
cucurbitacin K 2-O-beta-D-glucopyranoside 
curamycin A 
cyproterone +   
cytochalasin D  
D-3-sulfolactaldehyde 
D-galactaro-1,5-lactone 
daphnetoxin 
deisopropylatrazine  
demeclocycline +   
desmethylanhydrotetracycline 
dexamethasone phosphate  
diflorasone +   
dimethyl sulfide +  
dimethyl telluride 
dimethylselenide +  
DMG-MINO 
doxorubicin +   
doxycycline +   
dTDP-4-dehydro-3-methyl-2,6-dideoxy-beta-L-glucose 
elloramycin A 
epi-isochromophilone II 
ethylenediaminediacetic acid 
ethylenediaminetriacetic acid 
Euphorbia diterpenoid 3 
fludrocortisone acetate 
flumethasone +   
flumethasone pivalate 
fluorometholone +   
forskolin +   
GDP-valienol 
guamecycline 
guignardone N 
harziphilone 
humulone 
hydrocortamate +  
hydrocortisone caproate 
hydrocortisone succinate  
hydroxylamine +   
iodtetracycline(1-) +  
isariotin F 
keto-L-tagatose 
kidjoranin-3-O-alpha-diginopyranosyl-(1->4)-beta-cymaropyranoside 
kidjoranin-3-O-beta-digitoxopyranoside 
leucomethylene blue 
leucosesterlactone 
leucosesterterpenone 
longirostrerone B 
lymecycline 
maleamic acid 
maleylacetic acid 
meclocycline  
medroxyprogesterone +   
megestrol +   
methacycline 
methyl prednisolone-16-carboxylate +  
methyl prednisolone-16alpha-carboxylate 
methylprednisolone acetate 
microdiplodiasol 
minocycline +   
mometasone +   
monoisodecyl phthalate 
Mupirocin calcium hydrate 
myrothenone A 
N-(2,6-diethylphenyl)-2-chloroacetamide  
N-formimidoyl-L-aspartic acid 
N-methyl-L-glutamic acid 
nemorubicin  
neurolenin A 
neurolenin B 
neurolenin C 
neurolenin D 
ochracenomicin A 
ochratoxin alpha +   
otophylloside B 
oxytetracycline  
para-isopropylaniline 
phorbol +   
phorbol 12,13-dibutanoate  
phorbol 13-acetate 12-myristate  
phorbol 13-butanoate 
phorbol 13-decanoate 12-tiglate 
pipacycline 
polyketomycin 
polypodine B 
preaustinoid A 
preaustinoid A1 
prednisolone +   
prednisolone-16-carboxylic acid +  
prednisolone-16alpha-carboxylic acid +  
prednisone +   
Pretetramid +  
pretetramide +  
pterolinus I 
purpurquinone A 
purpurquinone B 
purpurquinone C 
quinolin-2-ol  
robustaside E 
rolitetracycline 
S-(chloromethyl)glutathione 
sancycline 
sapintoxin D 
TAN-1612 
tetracenomycin C +  
tetracenomycin X 
tetracycline +   
tetrahydrocortisol 
tigecycline +   
tinyatoxin 
tixocortol +  
tixocortol pivalate 
triamcinolone +   
trichanolide 
trigoheterin E, (rel)- +  
valienone +  
viridicatumtoxin 

Synonyms
Exact Synonyms: (4S,4aS,5aR,6S,11aS,12aR)-4-(dimethylamino)-3,6,10,11a,12a-pentahydroxy-6-methyl-1,11,12-trioxo-1,4,4a,5,5a,6,11,11a,12,12a-decahydrotetracene-2-carboxamide
Related Synonyms: Formula=C22H24N2O9 ;   InChI=1S/C22H24N2O9/c1-20(31)8-5-4-6-10(25)12(8)16(27)22(33)11(20)7-9-14(24(2)3)15(26)13(18(23)29)17(28)21(9,32)19(22)30/h4-6,9,11,14,25-26,31-33H,7H2,1-3H3,(H2,23,29)/t9-,11+,14-,20+,21+,22-/m0/s1 ;   InChIKey=FWVRSACGGAUWNP-BWOONYPSSA-N ;   SMILES=C12=CC=CC(=C1C([C@]3([C@](C[C@]4([C@@H](C(O)=C(C([C@@]4(O)C3=O)=O)C(N)=O)N(C)C)[H])([C@]2(C)O)[H])O)=O)O
Xrefs: MetaCyc:CPD-19252 ;   PMID:23999299 "Europe PMC"
Cyclic Relationships: is_tautomer_of CHEBI:132727

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.