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Term:
Parent Terms Term With Siblings Child Terms
(13R)-13-dihydrocarminomycin 
(1R,2S)-nortilidine +  
(1S,2R)-nortilidine +  
(2S)-2-(4-\{[(1R,2S)-2-hydroxycyclopentyl]methyl\}phenyl)propanoic acid 
(3,5-dihydroxyphenyl)acetic acid 
(5-hydroxyindol-3-yl)acetic acid +   
(6-methoxy-2-naphthyl)acetic acid 
(S)-3-\{[5-(methoxymethyl)pyrazolo[1,5-a]pyrimidin-7-yl](methyl)amino\}propane-1,2-diol 
(S)-3-\{[6-(methoxymethyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino\}-2,3-dihydrothiophene 1,1-dioxide 
1',4-dihydroxymidazolam 
1,1,1,3,3,3-hexafluoropropan-2-ol  
1,2,4-triazole-3-carboxamide +   
1-(3-chlorophenyl)piperazine  
1-(phenylmethyl)-4-(phenylmethylthio)pyrazolo[3,4-d]pyrimidine 
1-[(4-methylphenyl)methyl]-4-(1-pyrrolidinyl)pyrazolo[3,4-d]pyrimidine 
1-[(5,7-dimethyl-3-pyrazolo[1,5-a]pyrimidinyl)-oxomethyl]-4-piperidinecarboxylic acid ethyl ester 
1-azepan-1-yl-2-phenyl-2-(4-thioxo-1,4-dihydropyrazolo[3,4-d]pyrimidin-5-yl)ethanone adduct 
1-hydroxymidazolam +   
1-hydroxymidazolam beta-D-glucuronide  
1-Isopropyl-3-(3-pyridinylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 
1-NA-PP1 
1-NM-PP1 
1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 
1-tert-butyl-5-[(2,4-dichloro-5-fluorophenyl)methyl]-4-pyrazolo[3,4-d]pyrimidinone 
1-tert-butyl-5-[(2-chloro-6-fluoro-3-methylphenyl)methyl]-4-pyrazolo[3,4-d]pyrimidinone 
1-tert-butyl-5-[(4-fluoro-2,6-dimethylphenyl)methyl]-4-pyrazolo[3,4-d]pyrimidinone 
1-tert-butyl-5-[(6-chloro-2-fluoro-3-methylphenyl)methyl]-4-pyrazolo[3,4-d]pyrimidinone 
1-tert-butyl-5-[[3-[(1-tert-butyl-4-oxo-5-pyrazolo[3,4-d]pyrimidinyl)methyl]-2-fluorophenyl]methyl]-4-pyrazolo[3,4-d]pyrimidinone 
10,11-trans-dihydroxy-10,11-dihydrocarbamazepine +  
12-hydroxynevirapine 
2,3,4-trihydroxbenzophenone 
2,6-dimethylaniline +   
2,7-Dimethyl-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine 
2-(4-amino-1-propan-2-yl-2H-pyrazolo[3,4-d]pyrimidin-3-ylidene)-5-indolol 
2-[[4-amino-5-(3-chlorophenyl)-3-methyl-6-pyrazolo[3,4-d]pyrimidinyl]thio]-N-(2-methoxyethyl)butanamide 
2-[[4-amino-5-(4-bromophenyl)-3-methyl-6-pyrazolo[3,4-d]pyrimidinyl]thio]-N-(2-oxolanylmethyl)acetamide 
2-amino-3-[(2-fluorophenyl)hydrazinylidene]-5-methyl-7-pyrazolo[1,5-a]pyrimidinone 
2-amino-3-[(2-fluorophenyl)hydrazinylidene]-7-imino-5-methyl-6-pyrazolo[1,5-a]pyrimidinecarbonitrile 
2-formylbenzoic acid 
2-hydroxyibuprofen 
2-methoxyacetaminophen glucuronide 
2-methoxyacetaminophen glucuronide(1-) 
2-methoxyacetaminophen sulfate 
2-methoxyacetaminophen sulfate(1-) 
2NM-PP1 
3'-hydroxy-4'-methoxydiclofenac 
3'-hydroxydiclofenac 
3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl-[5-(4-bromophenyl)-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-3-yl]methanone 
3,4-dihydroxymandelic acid  
3,5-dinitrosalicylic acid hydrazide 
3-(3-chlorophenyl)azo-5,7-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-2-one 
3-(4-amino-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenol 
3-BrB-PP1 
3-chloro-5-(2-furanyl)-N-propan-2-yl-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamide 
3-chloro-N-(2-furanylmethyl)-5-thiophen-2-yl-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamide 
3-chlorobenzoic acid 
3-hydroxy-2,2-dimethylbutyric acid 
3-hydroxymethylantipyrine 
3-oxociprofloxacin 
3H-pyrazolo[4,3-d]pyrimidin-7-ol 
4',5-dihydroxydiclofenac 
4'-hydroxy torasemide 
4'-hydroxydiclofenac  
4-(\{5-[(trans-4-aminocyclohexyl)amino]-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl\}amino)-N,N-dimethylbenzenesulfonamide 
4-(acetylamino)-3-hydroxyphenyl hydrogen sulfate 
4-(acetylamino)-3-hydroxyphenyl sulfate 
4-(methylamino)antipyrine 
4-(trifluoromethyl)phenol 
4-acetamidoantipyrine 
4-amino-1-tert-butyl-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-2-ium 
4-aminoantipyrine 
4-ethoxyaniline +   
4-formylaminoantipyrine 
4-hydroxy-2,6-dimethylaniline 
4-hydroxy-6-methylaniline 
4-hydroxymidazolam +   
4-hydroxymidazolam beta-D-glucuronide 
4-hydroxypropofol 
4-morpholinyl-[5-thiophen-2-yl-7-(trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinyl]methanone 
4H-pyrazolo[3,4-d]pyrimidine-4,6(5H)-dione 
5'-hydroxyomeprazole  
5,7-dimethyl-3-phenyldiazenyl-1H-pyrazolo[1,5-a]pyrimidin-2-one 
5,7-dimethyl-N-phenyl-2-pyrazolo[1,5-a]pyrimidinamine 
5-(1,3-benzodioxol-5-yl)-N-(2-furanylmethyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamide 
5-(1-ethyl-3-methyl-4-pyrazolyl)-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxylic acid 
5-(2-furanyl)-N-[1-[(2-methylphenyl)methyl]-3-pyrazolyl]-7-(trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinecarboxamide 
5-(3-bromophenyl)-7-[(pyridin-4-ylmethyl)amino]-1H-pyrazolo[1,5-a]pyrimidin-8-ium 
5-(methoxymethyl)-2-thiophen-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one 
5-[(2-bromo-6-chlorophenyl)methyl]-1-tert-butyl-4-pyrazolo[3,4-d]pyrimidinone 
5-[(2-bromophenyl)methyl]-1-tert-butyl-4-pyrazolo[3,4-d]pyrimidinone 
5-[2-(but-3-en-1-yloxy)-5-(1-hydroxyvinyl)pyridin-3-yl]-3-ethyl-2-(1-ethylazetidin-3-yl)-1,2,6,7a-tetrahydro-7H-pyrazolo[4,3-d]pyrimidin-7-one 
5-carboxy-2'-deoxyuridine 
5-chloro-N-[4-(methylsulfonyl)phenyl]pyrazolo[1,5-a]pyrimidin-7-amine 
5-ethyl-5-methyl-1,3-oxazolidine-2,4-dione +  
5-fluorouridine 5'-monophosphate 
5-hydroxydiclofenac  
5-hydroxydiclofenac quinone imine 
5-iodo-5,6-dihydro-6-azatubercidin 
5-O-desmethyldonepezil 
6-(3,4-dihydroxybenzyl)-3-ethyl-1-(2,4,6-trichlorophenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one 
6-[(2-chloro-4-fluorophenyl)methyl]-5-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid methyl ester 
6-[(2-fluorophenyl)methyl]-5-methyl-N-(3-methylbutyl)-7-oxo-1H-pyrazolo[1,5-a]pyrimidine-3-carboxamide 
6-azauridine +   
6-bromo-3-(1-methyl-4-pyrazolyl)-5-(3-piperidinyl)-7-pyrazolo[1,5-a]pyrimidinamine 
6-ethyl-2,5-dimethyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile 
6-ethyl-2,7-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-5-one 
6-ethyl-5-methyl-2-thiophen-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one 
6-formylpterin  
7-hydroxyticlopidine 
7-isobutyl-5-methyl-2-(1-naphthylmethyl)-3-(4-pyridyl)alloxanthine 
8-aza-7-deaza-cAMP 
8-azaadenine +  
[5-hydroxy-3-methyl-5-(trifluoromethyl)-4,5-dihydropyrazol-1-yl]-[5-phenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone 
acetaminophen O-beta-D-glucosiduronic acid  
acetohydrazide +   
ACT-132577 +   
ACT-333679 +  
adavosertib  
adefovir +   
allopurinol +   
alloxanthine +   
A pyrazolopyrimidine that is 4,5,6,7-tetrahydro-H-pyrazolo[3,4-d]pyrimidine substituted by oxo groups at positions 4 and 6.
aripiprazole  
aspalathin  
atenolol acid 
atenolol-desisopropyl 
azure B  
BAY 73-6691 
brivanib +  
carbamazepine-10,11-epoxide  
carboxyibuprofen 
carboxyibuprofen(2-) 
ceftaroline +   
clopidogrel carboxylic acid 
CNDAC +  
cotinine N-oxide 
cyclosporin A metabolite M1 +  
cyclosporin A metabolite M10 
cyclosporin A metabolite M13 
cyclosporin A metabolite M16 +  
cyclosporin A metabolite M17 +  
cyclosporin A metabolite M18 +  
cyclosporin A metabolite M1A 
cyclosporin A metabolite M1cAL 
cyclosporin A metabolite M21 +  
cyclosporin A metabolite M25 
cyclosporin A metabolite M26 
cyclosporin A metabolite M8 +  
cyclosporin A metabolite M9 
cyclosporin A sulfate 
D617 
desloratadine +   
desmethyl loperamide 
desmethyldoxepin +  
desmethylnaproxen  
desmethylnaproxen sulfate 
desmethylnaproxen(1-) 
desmethylranitidine 
diclofenac beta-D-glucosiduronic acid 
didesethylflurazepam 
dinaciclib  
dioxoaminopyrine 
DM-4103 
DM-4107 
DMH1 
DMH4 
dorsomorphin  
doxorubicinol 
ethisterone  
ethyl 2-hydroxy-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate +   
febuxostat  
fenofibric acid 
formycin +  
formycin 3',5'-cyclic phosphate 
gartisertib 
glycinexylidide +  
GS-441524 +   
GS-441524 monophosphate 
GS-443902 
hydroxy torasemide 
Hydroxyakalone 
hydroxyalbendazole 
hydroxyfenbendazole 
ibrutinib  
imidaprilat  
Imidazosagatriazinone 
indometacin +   
INDY +  
ixazomib +   
LDN-212854 
LSM-16602 
LSM-20838 
LSM-28486 
LSM-32147 
mevinolinic acid 
monoethylglycinexylidide +   
monomethyl fumarate 
N(4)-hydroxycytidine +   
N,N-didesmethylvenlafaxine 
N,N-diethylglycine 
N,O-didesmethylvenlafaxine 
N-(1,3-benzodioxol-5-yl)-6-bromo-2-pyrazolo[1,5-a]pyrimidinecarboxamide 
N-(2,3-dihydro-1H-inden-5-yl)-5,7-dimethyl-3-pyrazolo[1,5-a]pyrimidinecarboxamide 
N-(2,4-dimethylphenyl)-1-methyl-4-pyrazolo[3,4-d]pyrimidinamine 
N-(2-[(2-aminoethyl)(methyl)amino]-5-\{[3-cyano-7-(cyclopropylamino)pyrazolo[1,5-a]pyrimidin-5-yl]amino\}phenyl)acetamide 
N-(2-furanylmethyl)-1-(phenylmethyl)-4-pyrazolo[3,4-d]pyrimidinamine 
N-(2-furanylmethyl)-3-(2,4,8,10-tetramethyl-3-pyrido[2,3]pyrazolo[2,4-a]pyrimidinyl)propanamide 
N-(2-furanylmethyl)-5,7-dimethyl-6-[(3-methylphenyl)methyl]-3-pyrazolo[1,5-a]pyrimidinecarboxamide 
N-(2-furanylmethyl)-5-thiophen-2-yl-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamide 
N-(3-cyano-4-ethyl-5-methyl-2-thiophenyl)-3-pyrazolo[1,5-a]pyrimidinecarboxamide 
N-(3-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 
N-(4-\{1-[4-(4-acetylpiperazin-1-yl)-trans-cyclohexyl]-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl\}-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide 
N-(4-\{4-amino-1-[1-(tetrahydro-2H-pyran-4-yl)piperidin-4-yl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl\}-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide 
N-(4-\{4-amino-1-[4-(4-methylpiperazin-1-yl)-trans-cyclohexyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl\}-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide 
N-[(1,3-dimethyl-4-pyrazolyl)methyl]-5-(2-furanyl)-N-methyl-7-(trifluoromethyl)-2-pyrazolo[1,5-a]pyrimidinecarboxamide 
N-acetylsulfamethoxazole 
N-benzyl-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine 
N-Butyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine 
N-desmethylvenlafaxine 
N-methylthiourea  
N3-(4-fluorophenyl)-2H-pyrazolo[3,4-d]pyrimidine-3,4-diamine 
N5-(2,4-dichlorophenyl)pyrazolo[3,4-d]pyrimidine-4,5-diamine 
N5-(6-aminohexyl)-N7-(phenylmethyl)-3-propan-2-ylpyrazolo[1,5-a]pyrimidine-5,7-diamine 
NAV2729 
nelociguat 
nitrazepam +   
nitrososulfadiazine 
nitrososulfapyridine 
norfentanyl 
nortriptyline  
norverapamil  
O-desethyl candesartan 
O-desmethylvenlafaxine 
omega-hydroxyfinasteride 
oxidopamine  
oxyphenbutazone +   
paliperidone 
paracetamol sulfate +   
pedalitin  
perindoprilat 
PF-00835231 +  
PF-4800567 
PP121 
PP2 
prednisolone +   
procainamide 4-hydroxylamine 
procyanidin C1 
proglumide +  
promazine sulfoxide 
psilocin +  
purpurogallin  
pyrazine-2-carboxylic acid  
Pyrazolopyrimidinone 
pyrazophos  
pyridine N-oxide +   
rac-nortilidine 
ramiprilat  
ranitidine N-oxide 
ranitidine-S-oxide 
repotrectinib 
ribavirin 5'-diphosphate 
ribavirin 5'-monophosphate 
ribavirin 5'-triphosphate 
ribavirin carboxylic acid 
ritalinic acid  
S-(5-acetamido-2-hydroxyphenyl)-N-acetyl-L-cysteinate 
S-(5-acetamido-2-hydroxyphenyl)-N-acetyl-L-cysteine 
S-3100-CA +   
sapanisertib  
SGC-CK2-1 
sildenafil +   
SKLB-677 
SN-38 +   
SN-38 carboxylic acid 
spiraprilat +   
sulfadiazine hydroxylamine 
sulfapyridine hydroxylamine 
sulfociprofloxacin 
tedizolid 
tenofovir (anhydrous) +   
teriflunomide  
theophylline +   
tisopurine 
torasemide carboxylic acid 
torkinib 
trandolaprilat +   
uridine +   
WR-1065  
zaleplon  
zofenoprilat 

Synonyms
Exact Synonyms: 1H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione
Related Synonyms: Formula=C5H4N4O2 ;   InChI=1S/C5H4N4O2/c10-4-2-1-6-9-3(2)7-5(11)8-4/h1H,(H3,6,7,8,9,10,11) ;   InChIKey=HXNFUBHNUDHIGC-UHFFFAOYSA-N ;   Oxipurinol ;   Oxoallopurinol ;   Oxypurinol ;   SMILES=O=c1[nH]c2[nH]ncc2c(=O)[nH]1
Alternate IDs: CHEBI:22360 ;   CHEBI:2603
Xrefs: BPDB:2154 ;   CAS:2465-59-0 ;   HMDB:HMDB0000786 ;   KEGG:C07599 ;   KEGG:D02365
Xref Mesh: MESH:D010117
Xrefs: PMID:18484017 ;   PMID:23751350 ;   PMID:24184830 ;   PMID:24591375 ;   Reaxys:139956 ;   Wikipedia:Oxypurinol

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