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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:cortisol signaling pathway
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Accession:PW:0000569 term browser browse the term
Definition:Cortisol, also known as hydrocortisone, is the most important glucocorticoid. Cortisol signaling, via binding to the glucocorticoid receptor present in almost every animal cell, is essential for many cellular and physiological functions.
Synonyms:related_synonym: PID:200030
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cortisol signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crebbp CREB binding protein ISO RGD PMID:11306337 RGD:5147892 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Dnaja2 DnaJ heat shock protein family (Hsp40) member A2 ISO RGD PMID:16610357 RGD:5144125 NCBI chr19:21,497,792...21,516,904
Ensembl chr19:21,497,729...21,516,901 		JBrowse link
G Ep300 E1A binding protein p300 ISO RGD PMID:11306337 RGD:5147892 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 ISO RGD PMID:16610357 RGD:5144125 NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 ISO RGD PMID:16610357 RGD:5144125 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 ISO RGD PMID:16610357 RGD:5144125 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 ISO RGD PMID:16610357 RGD:5144125 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 ISO RGD PMID:16610357 RGD:5144125 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001 		JBrowse link
G Kat2b lysine acetyltransferase 2B ISO RGD PMID:11306337 RGD:5147892 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064 		JBrowse link
G Med1 mediator complex subunit 1 TAS
ISO		 RGD PMID:11306337 PMID:11306337 RGD:5147892, RGD:5147892 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Med14 mediator complex subunit 14 ISO RGD PMID:11306337 RGD:5147892 NCBI chr  X:10,036,749...10,127,910
Ensembl chr  X:10,036,805...10,126,240 		JBrowse link
G Ncoa1 nuclear receptor coactivator 1 ISO RGD PMID:19818358 PMID:11306337 RGD:5144138, RGD:5147892 NCBI chr 6:27,232,609...27,507,992
Ensembl chr 6:27,232,611...27,475,664 		JBrowse link
G Ncoa2 nuclear receptor coactivator 2 ISO RGD PMID:19818358 PMID:11306337 RGD:5144138, RGD:5147892 NCBI chr 5:5,835,642...6,069,693
Ensembl chr 5:5,835,706...6,067,451 		JBrowse link
G Ncoa3 nuclear receptor coactivator 3 ISO RGD PMID:19818358 PMID:11306337 RGD:5144138, RGD:5147892 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594 		JBrowse link
G Ncor1 nuclear receptor co-repressor 1 ISO RGD PMID:20801081 RGD:5147413 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032 		JBrowse link
G Ncor2 nuclear receptor co-repressor 2 ISO RGD PMID:20801081 RGD:5147413 NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO RGD PMID:16610357 RGD:5144125 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Ptges3 prostaglandin E synthase 3 ISO RGD PMID:16610357 RGD:5144125 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084 		JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 ISO RGD PMID:11306337 RGD:5147892 NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975 		JBrowse link
G Stip1 stress-induced phosphoprotein 1 ISO RGD PMID:16610357 RGD:5144125 NCBI chr 1:204,209,433...204,228,452
Ensembl chr 1:204,178,932...204,228,476 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    signaling pathway 2646
      transcription factor mediated signaling pathway 460
        cortisol signaling pathway 20
          altered cortisol signaling pathway 0
Path 2
Term Annotations click to browse term
  pathway 6092
    signaling pathway 2646
      hormone signaling pathway 624
        lipid hormone signaling pathway 224
          steroid hormone signaling pathway 92
            corticosteroid signaling pathway 73
              glucocorticoid signaling pathway 21
                cortisol signaling pathway 20
                  altered cortisol signaling pathway 0
paths to the root