Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:c-Jun N-terminal kinases MAPK signaling pathway
go back to main search page
Accession:PW:0000313 term browser browse the term
Definition:A stress-induced MAPK pathway that regulates an array of processes such as gene expression, cell migration, cytoskeletal organization and apoptosis.
Synonyms:related_synonym: JNK cascade;   JNK signaling pathway
View Interactive Diagram


show annotations for term's descendants           Sort by:
c-Jun N-terminal kinases MAPK signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc42 cell division cycle 42 ISO RGD PMID:8910292 PMID:9305638 RGD:2293876, RGD:2293879 NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:154,839,631...154,876,627 		JBrowse link
G Dusp1 dual specificity phosphatase 1 ISO RGD PMID:17208316 RGD:2293881 NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644 		JBrowse link
G Dusp10 dual specificity phosphatase 10 ISO RGD PMID:17208316 RGD:2293881 NCBI chr13:98,145,317...98,183,304
Ensembl chr13:98,145,893...98,183,304 		JBrowse link
G Dusp16 dual specificity phosphatase 16 ISO RGD PMID:17208316 RGD:2293881 NCBI chr 4:169,278,118...169,361,508
Ensembl chr 4:169,278,118...169,361,508 		JBrowse link
G Dusp19 dual specificity phosphatase 19 ISO RGD PMID:11959862 RGD:2314491 NCBI chr 3:85,945,289...86,081,289 JBrowse link
G Dusp8 dual specificity phosphatase 8 ISO RGD PMID:17208316 RGD:2293881 NCBI chr 1:206,596,912...206,613,728
Ensembl chr 1:206,598,942...206,612,441 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 ISO
IDA 		RGD PMID:17306896 PMID:10051439 PMID:17064355 RGD:2293875, RGD:2298561, RGD:2298577 NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,844,034...50,947,185 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 ISO
IDA 		RGD PMID:17306896 PMID:10051439 PMID:15680699 PMID:17064355 RGD:2293875, RGD:2298561, RGD:2298567, RGD:2298577 NCBI chr12:7,389,032...7,398,377
Ensembl chr12:7,389,155...7,398,377 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:9305638 PMID:17306896 RGD:2293879, RGD:2293875 NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:45,081,889...45,149,897 		JBrowse link
G Map3k10 mitogen activated protein kinase kinase kinase 10 ISO RGD PMID:17306896 RGD:2293875 NCBI chr 1:92,083,376...92,101,676
Ensembl chr 1:92,083,376...92,101,676 		JBrowse link
G Map3k11 mitogen-activated protein kinase kinase kinase 11 ISO
IDA 		RGD PMID:8910292 PMID:17306896 PMID:15680699 PMID:17064355 RGD:2293876, RGD:2293875, RGD:2298567, RGD:2298577 NCBI chr 1:212,404,685...212,417,986
Ensembl chr 1:212,403,680...212,417,983 		JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 ISO RGD PMID:17306896 RGD:2293875 NCBI chr 7:135,507,082...135,527,396
Ensembl chr 7:135,508,790...135,515,137 		JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 ISO RGD PMID:17306896 RGD:2293875 NCBI chr11:92,596,436...92,741,717
Ensembl chr11:92,601,738...92,739,663 		JBrowse link
G Map3k2 mitogen activated protein kinase kinase kinase 2 ISO RGD PMID:9305638 PMID:17306896 RGD:2293879, RGD:2293875 NCBI chr18:24,081,444...24,153,940
Ensembl chr18:24,081,444...24,147,323 		JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 ISO RGD PMID:17306896 RGD:2293875 NCBI chr 3:77,538,146...77,697,540
Ensembl chr 3:77,537,956...77,697,538 		JBrowse link
G Map3k21 mitogen-activated protein kinase kinase kinase 21 ISO RGD PMID:17306896 RGD:2293875 NCBI chr19:70,776,233...70,810,889
Ensembl chr19:70,777,472...70,810,882 		JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 ISO RGD PMID:9305638 PMID:17306896 RGD:2293879, RGD:2293875 NCBI chr10:91,519,976...91,588,651
Ensembl chr10:91,519,888...91,588,651 		JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 ISO RGD PMID:9305638 PMID:17306896 RGD:2293879, RGD:2293875 NCBI chr 1:50,977,870...51,067,117
Ensembl chr 1:50,979,586...51,067,117 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO RGD PMID:12215209 PMID:17306896 RGD:2293875 RGD:2296020 NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:16,505,596...16,723,898 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 ISO RGD PMID:17306896 RGD:2293875 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:51,154,352...51,212,012 		JBrowse link
G Map3k9 mitogen-activated protein kinase kinase kinase 9 ISO RGD PMID:17306896 RGD:2293875 NCBI chr 6:107,155,008...107,220,304
Ensembl chr 6:107,161,534...107,220,061 		JBrowse link
G Mapk10 mitogen activated protein kinase 10 ISO
IDA 		RGD PMID:17306896 PMID:10051439 PMID:15680699 RGD:2293875, RGD:2298561, RGD:2298567 NCBI chr14:6,802,247...7,094,103
Ensembl chr14:6,802,295...7,094,100 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 ISO
IDA 		RGD PMID:17306896 PMID:10051439 PMID:17064355 RGD:2293875, RGD:2298561, RGD:2298577 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 ISO
IDA 		RGD PMID:17726577 PMID:15816852 RGD:2293880, RGD:1579811 NCBI chr 3:98,810,540...98,829,302
Ensembl chr 3:98,810,541...98,828,368 		JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 ISO RGD PMID:17726577 RGD:2293880 NCBI chr 7:122,406,350...122,416,602
Ensembl chr 7:122,406,350...122,416,602 		JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 ISO RGD PMID:17726577 RGD:2293880 NCBI chr10:14,422,936...14,463,387
Ensembl chr10:14,422,936...14,462,812 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 ISO
IDA 		RGD PMID:17306896 PMID:10051439 PMID:17064355 RGD:2293875, RGD:2298561, RGD:2298577 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228 		JBrowse link
G Rac1 Rac family small GTPase 1 ISO RGD PMID:8910292 PMID:9305638 RGD:2293876, RGD:2293879 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109 		JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 IMP RGD PMID:10811109 RGD:11534984 NCBI chr 3:33,296,211...33,414,119
Ensembl chr 3:33,296,230...33,414,119 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:15757900 RGD:1581337 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 ISO RGD PMID:12215209 RGD:2296020 NCBI chr 3:28,740,098...28,764,752
Ensembl chr 3:28,740,098...28,764,691 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    signaling pathway 2635
      mitogen activated protein kinase signaling pathway 299
        stress-regulated MAPK signaling pathway 70
          c-Jun N-terminal kinases MAPK signaling pathway 31
            altered c-Jun N-terminal kinase MAPK signaling pathway 0
Path 2
Term Annotations click to browse term
  pathway 6091
    signaling pathway 2635
      kinase mediated signaling pathway 602
        serine/threonine-specific kinase mediated signaling pathway 476
          mitogen activated protein kinase signaling pathway 299
            stress-regulated MAPK signaling pathway 70
              c-Jun N-terminal kinases MAPK signaling pathway 31
                altered c-Jun N-terminal kinase MAPK signaling pathway 0
paths to the root