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RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Klatskin's tumor
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Accession:DOID:4927 term browser browse the term
Definition:An intrahepatic cholangiocarcinoma arising near or at the confluence of the right and left hepatic ducts. (DO)
Synonyms:exact_synonym: Klatskin tumor;   Klatskin tumour;   Klatskin's tumour;   Klatskins tumor;   hilar cholangiocarcinoma;   hilar cholangiocarcinomas;   hilar cholangiocellular carcinoma;   perihilar cholangiocarcinoma;   perihilar extrahepatic bile duct carcinoma
 primary_id: MESH:D018285
 alt_id: DOID:5246
 xref: EFO:1001005;   EFO:1001959;   GARD:10175;   NCI:C36077;   ORDO:99978
For additional species annotation, visit the Alliance of Genome Resources.

show annotations for term's descendants           Sort by:
Klatskin's tumor term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway ISO ClinVar Annotator: match by term: Klatskin tumor ClinVar PMID:25741868 PMID:28492532 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Arid1a AT-rich interaction domain 1A disease_progression ISO DNA:deletions RGD PMID:33387086 RGD:126848756 NCBI chr 5:145,908,173...145,981,552
Ensembl chr 5:145,908,181...145,985,564
JBrowse link
G Gata6 GATA binding protein 6 sexual_dimorphism ISO DNA:mutations RGD PMID:33387086 RGD:126848756 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532
JBrowse link
G Kmt2c lysine methyltransferase 2C onset ISO DNA:mutations RGD PMID:33387086 RGD:126848756 NCBI chr 4:9,620,638...9,834,787
Ensembl chr 4:9,609,627...9,833,539
JBrowse link
G Kras KRAS proto-oncogene, GTPase disease_progression ISO DNA:mutations RGD PMID:33387086 RGD:126848756 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Prex2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 sexual_dimorphism ISO DNA:substitutions, insertion/deletions: (human) RGD PMID:33387086 PMID:33387086 RGD:126848756, RGD:126848756 NCBI chr 5:7,937,692...8,253,112
Ensembl chr 5:7,942,573...8,253,068
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 21122
    disease of cellular proliferation 7653
      Neoplasms by Histologic Type 5252
        Glandular and Epithelial Neoplasms 3714
          carcinoma 3197
            adenocarcinoma 1709
              bile duct adenocarcinoma 139
                cholangiocarcinoma 139
                  intrahepatic cholangiocarcinoma 32
                    Klatskin's tumor 6
Path 2
Term Annotations click to browse term
  disease 21122
    disease of anatomical entity 18162
      gastrointestinal system disease 6981
        Digestive System Neoplasms 3838
          Gastrointestinal Neoplasms 3713
            gastrointestinal system benign neoplasm 236
              hepatobiliary benign neoplasm 184
                biliary tract benign neoplasm 155
                  Bile Duct Neoplasms 152
                    bile duct cancer 150
                      bile duct carcinoma 139
                        bile duct adenocarcinoma 139
                          cholangiocarcinoma 139
                            intrahepatic cholangiocarcinoma 32
                              Klatskin's tumor 6
paths to the root