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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:oligodendroglioma
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Accession:DOID:3181 term browser browse the term
Definition:A relatively slow-growing glioma that is derived from oligodendrocytes and tends to occur in the cerebral hemispheres, thalamus, or lateral ventricle. They may present at any age, but are most frequent in the third to fifth decades, with an earlier incidence peak in the first decade. Histologically, these tumors are encapsulated, relatively avascular, and tend to form cysts and microcalcifications. Neoplastic cells tend to have small round nuclei surrounded by unstained nuclei. The tumors may vary from well-differentiated to highly anaplastic forms. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2052; Adams et al., Principles of Neurology, 6th ed, p655)
Synonyms:exact_synonym: Mixed Oligodendroglioma Astrocytoma;   Mixed Oligodendroglioma Ependymoma;   mixed oligodendroglioma-astrocytomas;   mixed oligodendroglioma-ependymomas;   oligodendroblastoma;   oligodendroblastomas;   oligodendroglial neoplasm;   oligodendroglial tumor;   oligodendrogliomas;   well differentiated oligodendroglioma;   well-differentiated oligodendrogliomas
 primary_id: MESH:D009837
 xref: GARD:9953;   NCI:C129319;   NCI:C3288;   NCI:C6960
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
 
oligodendroglioma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atrx ATRX, chromatin remodeler ISO ClinVar Annotator: match by term: Oligodendroglioma ClinVar NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta disease_progression ISO RGD PMID:15750623 RGD:13702479 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Cic capicua transcriptional repressor ISO ClinVar Annotator: match by term: Oligodendroglioma ClinVar NCBI chr 1:80,853,920...80,880,537
Ensembl chr 1:80,853,920...80,880,532
JBrowse link
G Dtx1 deltex E3 ubiquitin ligase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21127729 NCBI chr12:35,849,647...35,880,835
Ensembl chr12:35,849,617...35,880,838
JBrowse link
G Egf epidermal growth factor susceptibility ISO DNA:polymorphism:promoter:GG genotypes were associated with increased risk. RGD PMID:17473192 RGD:13702474 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Gdnf glial cell derived neurotrophic factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:19138852 NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Hes1 hes family bHLH transcription factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21127729 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21127729 NCBI chr 2:93,096,706...93,100,316
Ensembl chr 2:93,095,498...93,100,312
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Oligodendroglioma
CTD
ClinVar
PMID:18772396 PMID:19657110 PMID:19798509 PMID:19818334 PMID:20160062 More... NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20160062 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase ISO DNA:hypermethylation:promoter (human) RGD PMID:15455350 RGD:2317688 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Ptges3 prostaglandin E synthase 3 ISO protein:increased expression:brain cortex, white matter (human) RGD PMID:19347995 RGD:5688067 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
JBrowse link
G Rb1 RB transcriptional corepressor 1 disease_progression ISO RGD PMID:15970925 RGD:13782064 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
anaplastic oligodendroglioma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cic capicua transcriptional repressor ISO ClinVar Annotator: match by term: Oligodendroglioma, anaplastic ClinVar NCBI chr 1:80,853,920...80,880,537
Ensembl chr 1:80,853,920...80,880,532
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 17445
    disease of cellular proliferation 7088
      cancer 5043
        cell type cancer 3431
          high grade glioma 629
            oligodendroglioma 13
              adult oligodendroglioma 0
              anaplastic oligodendroglioma + 1
              brain oligodendroglioma + 0
              childhood oligodendroglioma 0
              spinal cord oligodendroglioma 0
Path 2
Term Annotations click to browse term
  disease 17445
    disease of anatomical entity 16777
      nervous system disease 12215
        central nervous system disease 10506
          Central Nervous System Neoplasms 1376
            Brain Neoplasms 1317
              brain cancer 707
                high grade glioma 629
                  oligodendroglioma 13
                    adult oligodendroglioma 0
                    anaplastic oligodendroglioma + 1
                    brain oligodendroglioma + 0
                    childhood oligodendroglioma 0
                    spinal cord oligodendroglioma 0
paths to the root