Coronavirus infectious disease - Ontology Report - Rat Genome Database

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RGD DISEASE ONTOLOGY - ANNOTATIONS

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RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:	Coronavirus infectious disease	go back to main search page
Accession:	DOID:0080599	browse the term
Definition:	A viral infectious disease that has_material_basis_in Coronavirus. (DO)
Synonyms:	exact_synonym:	Coronavirus Infections; Coronavirus infection
	primary_id:	MESH:D018352
	xref:	EFO:0007224

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Rat (1024) Mouse (1044) Human (1395) Chinchilla (909) Bonobo (1010) Dog (1004) Squirrel (931) Pig (991) Green Monkey (989) Naked Mole-rat (904) All
Genes (1024)

Coronavirus infectious disease

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

angiotensin I converting enzyme

Severe Acute Respiratory Syndrome

RGD

NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131

G

angiotensin converting enzyme 2

CTD Direct Evidence: marker/mechanism

PMID:14647384 PMID:16007097 PMID:19453650 PMID:19625462 PMID:22496216 More...

NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977

G

C-C motif chemokine ligand 2

CTD Direct Evidence: marker/mechanism

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 3

RGD

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

G

C-C motif chemokine receptor 1

NCBI chr 8:123,556,286...123,561,841

G

C-C motif chemokine receptor 2

NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100

G

C-C motif chemokine receptor 5

Respiratory Syndrome, Severe Acute; mRNA:increased expression:lung (mouse)

PMID:19906920 PMID:11543653

RGD:4891446, RGD:14401732

NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260

G

CD209c molecule

RGD

NCBI chr12:1,936,233...1,943,841
Ensembl chr12:1,936,396...1,942,040

G

CD209d molecule

NCBI chr12:1,891,109...1,897,559
Ensembl chr12:1,891,113...1,901,171

G

cathepsin L

CTD Direct Evidence: marker/mechanism

PMID:16081529 PMID:23678171 PMID:27733646

NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548

G

C-X-C motif chemokine ligand 10

RGD

PMID:19626487 PMID:19906920

RGD:27095957, RGD:4891446

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

G

C-X-C motif chemokine ligand 2

RGD

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

G

C-X-C motif chemokine ligand 3

RGD

NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511

G

dipeptidylpeptidase 4

CTD Direct Evidence: marker/mechanism

NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901

G

epidermal growth factor receptor

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

interferon beta 1

CTD Direct Evidence: therapeutic

NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523

G

interferon gamma

RGD

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

interleukin 10

RGD

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 2

RGD

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 5

RGD

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

G

interleukin 6

Severe Acute Respiratory Syndrome;protein:increased expression:lung

RGD

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

mitogen activated protein kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

mannose binding lectin 2

Severe Acute Respiratory Syndrome; DNA:mutations:5' utr, exon:g.-221G>C, p.G54N (human)

RGD

NCBI chr 1:228,016,439...228,024,736

G

mucin 4, cell surface associated

NCBI chr11:68,008,245...68,053,242

G

MYD88, innate immune signal transduction adaptor

NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415

G

phosphatidylinositol 4-kinase beta

CTD Direct Evidence: marker/mechanism

NCBI chr 2:182,540,377...182,572,684
Ensembl chr 2:182,540,567...182,588,488

G

protein phosphatase 1, regulatory (inhibitor) subunit 14c

NCBI chr 1:39,773,403...39,886,970
Ensembl chr 1:39,773,403...39,886,956

G

serpin family E member 1

NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657

G

surfactant protein D

Severe Acute Respiratory Syndrome;protein:increased expression:lung

RGD

NCBI chr16:17,046,491...17,058,968
Ensembl chr16:17,046,483...17,059,927

G

TIR domain containing adaptor molecule 2

NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462

G

transmembrane serine protease 11D

CTD Direct Evidence: marker/mechanism

NCBI chr14:21,707,336...21,769,398
Ensembl chr14:21,707,336...21,769,396

G

tumor necrosis factor

RGD

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

COVID-19

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-2-macroglobulin

severity

DNA:SNPs: :
mRNA:decreased expression:peripheral blood mononuclear cell (human)

PMID:32228226 PMID:32747830

RGD:28912744, RGD:38500238

NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786

G

ATP binding cassette subfamily B member 1A

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily D member 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr X:151,428,334...151,450,115
Ensembl chr X:151,428,578...151,450,115

G

ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase

susceptibility

DNA:polymorphism:cds:allele A, allele O (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:32558485 PMID:32379894

NCBI chr 3:10,162,087...10,182,835
Ensembl chr 3:10,162,096...10,191,423

G

1-aminocyclopropane-1-carboxylate synthase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:79,805,254...79,820,830
Ensembl chr 3:79,806,587...79,820,835

G

angiotensin I converting enzyme

severity
no_association

DNA:insertion/deletion:intron 16:

RGD

PMID:32286246 PMID:32386188

RGD:30309199, RGD:30309201

NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131

G

angiotensin converting enzyme 2

severity

human gene in a mouse model
CTD Direct Evidence: marker/mechanism|therapeutic
DNA:insertion/deletion:intron 16:

MouseDO
CTD
RGD

PMID:31996437 PMID:32061198 PMID:32081428 PMID:32092392 PMID:32117569 More...

RGD:30310239, RGD:151347433, RGD:151347432, RGD:32716393

NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977

G

aconitase 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261

G

activin A receptor type 1B

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:132,286,266...132,329,679
Ensembl chr 7:132,286,275...132,329,673

G

activin A receptor like type 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591

G

ADAM metallopeptidase domain 15

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113

G

ADAM metallopeptidase domain 9

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917

G

ADAM metallopeptidase with thrombospondin type 1 motif, 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103

G

ADAM metallopeptidase with thrombospondin type 1 motif, 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:34,920,992...35,126,465
Ensembl chr10:34,921,049...35,123,821

G

ArfGAP with dual PH domains 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:65,138,006...65,166,147
Ensembl chr10:65,138,020...65,165,604

G

adhesion G protein-coupled receptor B2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:142,299,190...142,362,540
Ensembl chr 5:142,331,329...142,362,540

G

adrenomedullin

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654

G

adenosine A3 receptor

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357

G

ADP-ribosylarginine hydrolase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr11:62,299,831...62,306,170
Ensembl chr11:62,299,793...62,306,931

G

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:90,039,720...90,475,196
Ensembl chr 9:90,039,605...90,470,958

G

1-acylglycerol-3-phosphate O-acyltransferase 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:9,416,837...9,428,567
Ensembl chr 3:9,416,843...9,428,371

G

angiotensinogen

CTD Direct Evidence: marker/mechanism

NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977

G

angiotensin II receptor, type 1a

associated with hypertension

RGD

NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946

G

AHNAK nucleoprotein

mRNA:decreased expression:CD4+ T cells (human)

NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926

G

axin interactor, dorsalization associated

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr13:94,940,311...94,967,920
Ensembl chr13:94,939,741...94,967,920

G

aminoacyl tRNA synthetase complex-interacting multifunctional protein 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr12:10,701,194...10,710,772
Ensembl chr12:10,701,194...10,710,769

G

apical junction component 1 homolog

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:8,394,942...8,401,323
Ensembl chr 3:8,392,889...8,401,321

G

adenylate kinase 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:141,308,650...141,364,633
Ensembl chr 5:141,346,063...141,364,632

G

adenylate kinase 4

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618

G

A-kinase anchoring protein 12

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886

G

A-kinase anchoring protein 5

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578

G

A-kinase interacting protein 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:163,734,730...163,743,648
Ensembl chr 1:163,734,798...163,743,648

G

aldo-keto reductase family 1, member C3

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873

G

AKT serine/threonine kinase 3

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr13:88,943,708...89,225,831
Ensembl chr13:88,946,091...89,225,708

G

albumin

severity

RGD

PMID:32198776 PMID:32427582

RGD:30296673, RGD:30309200

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

activated leukocyte cell adhesion molecule

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954

G

aldehyde dehydrogenase 1 family, member L2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:20,254,246...20,305,793
Ensembl chr 7:20,254,233...20,305,776

G

aldehyde dehydrogenase 4 family, member A1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:151,880,002...151,905,491
Ensembl chr 5:151,830,701...151,925,345

G

aldehyde dehydrogenase 9 family, member A1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568

G

ALG14, UDP-N-acetylglucosaminyltransferase subunit

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:209,368,285...209,445,425
Ensembl chr 2:209,368,312...209,445,431

G

arachidonate 15-lipoxygenase, type B

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:53,892,496...53,901,812
Ensembl chr10:53,892,466...53,901,812

G

amphiphysin

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr17:45,739,385...45,982,905
Ensembl chr17:45,739,395...45,983,315

G

angiogenin

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr15:24,312,711...24,323,361

G

angiopoietin 2

severity

protein:increased expression:plasma (human)

RGD

NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804

G

angiopoietin-like 6

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:19,413,617...19,419,925
Ensembl chr 8:19,413,619...19,419,925

G

ankyrin repeat and LEM domain containing 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr16:18,076,413...18,082,356
Ensembl chr16:18,076,492...18,083,729

G

anillin, actin binding protein

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538

G

anoctamin 5

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:101,086,490...101,187,547
Ensembl chr 1:101,087,341...101,187,555

G

annexin A1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343

G

annexin A2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658

G

annexin A5

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369

G

adaptor related protein complex 2 subunit sigma 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:77,417,496...77,428,903
Ensembl chr 1:77,417,477...77,428,905

G

apolipoprotein L9a

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:109,140,871...109,149,799
Ensembl chr 7:109,140,871...109,147,649

G

amphiregulin

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535

G

Rho GTPase activating protein 12

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr17:51,588,810...51,702,417
Ensembl chr17:51,588,842...51,702,080

G

Rho GTPase activating protein 23

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:82,437,578...82,496,846
Ensembl chr10:82,394,648...82,496,504

G

Rho GTPase activating protein 29

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:210,060,036...210,132,572
Ensembl chr 2:210,071,199...210,132,028

G

Rho GTPase activating protein 31

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr11:62,038,635...62,151,564
Ensembl chr11:62,038,635...62,151,564

G

arkadia C-terminal like ring finger ubiquitin ligase 2C

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr18:70,984,566...71,100,836
Ensembl chr18:70,989,731...71,100,836

G

ADP ribosylation factor like GTPase 4C

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513

G

ADP-ribosylation factor like GTPase 4D

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr10:86,592,054...86,602,843
Ensembl chr10:86,595,661...86,602,836

G

ADP-ribosylation factor like GTPase 5B

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr17:77,955,864...77,979,895
Ensembl chr17:77,955,818...77,979,854

G

actin-related protein 2/3 complex inhibitor

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:133,864,288...133,873,124
Ensembl chr 1:133,864,265...133,873,124

G

ARVCF, delta catenin family member

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr11:82,588,137...82,645,832
Ensembl chr11:82,587,881...82,645,805

G

activating signal cointegrator 1 complex subunit 3

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr20:53,510,137...53,795,446
Ensembl chr20:53,510,184...53,790,165

G

asialoglycoprotein receptor 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:54,821,407...54,834,624
Ensembl chr10:54,821,438...54,834,617

G

assembly factor for spindle microtubules

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755

G

ATPase phospholipid transporting 11A

CTD Direct Evidence: marker/mechanism

NCBI chr16:76,657,752...76,767,640
Ensembl chr16:76,657,752...76,767,640

G

ATP synthase F1 subunit beta

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273

G

ATP synthase F1 subunit gamma

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr17:68,423,927...68,446,169
Ensembl chr17:68,423,909...68,608,367

G

ATP synthase membrane subunit c locus 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:58,810,535...58,813,185
Ensembl chr 3:58,810,535...58,814,279

G

ATP synthase peripheral stalk-membrane subunit b

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418

G

ATPase H+ transporting V1 subunit F

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:58,067,666...58,070,628

G

aurora kinase A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390

G

aurora kinase B

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837

G

activator of transcription and developmental regulator AUTS2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr12:24,104,187...25,194,123
Ensembl chr12:24,104,192...25,194,416

G

beta-1,3-glucuronyltransferase 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:25,087,123...25,114,692
Ensembl chr 8:25,087,547...25,113,395

G

beta-1,4-N-acetyl-galactosaminyl transferase 3

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:153,409,019...153,509,019
Ensembl chr 4:153,409,004...153,509,321

G

beta-1,4-galactosyltransferase 5

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 3:156,018,056...156,033,983
Ensembl chr 3:156,018,053...156,070,074

G

BAG cochaperone 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075

G

basic leucine zipper ATF-like transcription factor 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:203,467,291...203,479,428
Ensembl chr 1:203,468,097...203,475,889

G

branched chain amino acid transaminase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597

G

BCL11 transcription factor A

CTD Direct Evidence: marker/mechanism

NCBI chr14:98,029,018...98,124,181
Ensembl chr14:98,030,461...98,124,180

G

BCL11 transcription factor B

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:126,834,531...126,927,720
Ensembl chr 6:126,834,531...126,928,224

G

BCL2-related protein A1

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998

G

3-hydroxybutyrate dehydrogenase 1

severity

associated with cardiovascular system disease;protein:increased expression:blood (human)

RGD

NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671

G

brain-enriched guanylate kinase-associated

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:127,943,651...127,979,876
Ensembl chr 6:127,943,651...127,979,841

G

Bet1 golgi vesicular membrane trafficking protein

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 4:32,116,232...32,126,592
Ensembl chr 4:32,116,235...32,126,617

G

basic helix-loop-helix family, member e40

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774

G

baculoviral IAP repeat-containing 5

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

G

biliverdin reductase A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033

G

basic helix-loop-helix ARNT like 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:179,699,432...179,747,710
Ensembl chr 4:179,699,502...179,746,949

G

bMERB domain containing 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr10:1,779,834...1,946,586
Ensembl chr10:1,779,835...1,946,575

G

bone morphogenetic protein receptor type 1A

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616

G

BRCA2, DNA repair associated

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567

G

basigin (Ok blood group)

CTD Direct Evidence: therapeutic

NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387

G

Bruton tyrosine kinase

CTD Direct Evidence: marker/mechanism
protein:increased phosphorylation:blood, monocyte (human)

CTD
RGD

PMID:32503877 PMID:32503877

NCBI chr X:97,722,796...97,762,315
Ensembl chr X:97,722,802...97,761,853

G

BUB1 mitotic checkpoint serine/threonine kinase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650

G

BUB1 mitotic checkpoint serine/threonine kinase B

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547

G

basic leucine zipper and W2 domains 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:52,828,069...52,888,599
Ensembl chr 6:52,827,661...52,888,628

G

similar to human chromosome 1 open reading frame 115

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:96,422,308...96,432,044
Ensembl chr13:96,422,302...96,432,068

G

similar to human chromosome 1 open reading frame 21

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr13:63,982,587...64,199,676
Ensembl chr13:63,990,592...64,199,596

G

similar to human chromosome 14 open reading frame 119

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr15:28,146,368...28,151,422
Ensembl chr15:28,146,333...28,155,180

G

core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 4:35,930,981...35,966,100
Ensembl chr 4:35,928,104...35,961,831

G

similar to human chromosome 16 open reading frame 54

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:181,702,447...181,705,128
Ensembl chr 1:181,702,503...181,705,835

G

similar to human chromosome 19 open reading frame 84

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:93,835,378...93,837,316
Ensembl chr 1:93,835,395...93,836,380

G

complement C1q A chain

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534

G

complement C1q B chain

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407

G

complement C1q C chain

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017

G

complement C2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505

G

similar to human chromosome 1 open reading frame 162

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:193,410,730...193,420,824
Ensembl chr 2:193,412,971...193,420,030

G

complement C3

severity

protein:increased expression:serum (human)
DNA:SNPs: :rs1047286,rs2230203,rs2230199(human)

RGD

PMID:32434211 PMID:32747830

RGD:30310238, RGD:38500238

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

G

complement C3a receptor 1

mRNA:increased expression:bronchoalveolar lavage (human)
mRNA:increased expression:peripheral blood mononuclear cell (human)

PMID:32228226 PMID:32407669

RGD:28912744 RGD:30296672

NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701

G

complement component 4 binding protein, alpha

severity

DNA:SNP: :rs61821041(human)

RGD

NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205

G

complement component 4 binding protein, beta

severity

DNA:SNP: :rs45574833(human)

RGD

NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817

G

complement C5

severity

protein:increased expression:plasma (human)
mRNA:increased expression:peripheral blood mononuclear cell (human)

PMID:32228226 PMID:32417135

RGD:28912744, RGD:30310235

NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994

G

calcium binding protein 4

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:201,428,671...201,442,950
Ensembl chr 1:201,428,672...201,433,172

G

calcium voltage-gated channel auxiliary subunit alpha2delta 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:108,072,208...108,203,516
Ensembl chr 8:108,072,454...108,203,173

G

calcitonin-related polypeptide alpha

severity
disease_progression

associated with diabetes mellitus

RGD

PMID:32198776 PMID:32345579 PMID:32220650

RGD:30296673, RGD:30296681, RGD:30296674

NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105

G

calcitonin receptor like receptor

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910

G

calmodulin 2

mRNA:decreased expression:CD4+ T cells (human)

NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287

G

calcium/calmodulin-dependent protein kinase II inhibitor 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:150,674,819...150,676,600
Ensembl chr 5:150,673,507...150,676,600

G

cathelicidin antimicrobial peptide

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543

G

capping actin protein, gelsolin like

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856

G

calpain, small subunit 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:85,444,613...85,454,861
Ensembl chr 1:85,444,608...85,454,795

G

capping actin protein of muscle Z-line subunit alpha 2

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 4:45,978,142...46,014,032
Ensembl chr 4:45,977,807...46,013,864

G

carbonic anhydrase 11

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:96,169,900...96,175,191
Ensembl chr 1:96,170,080...96,175,191

G

caspase recruitment domain family, member 6

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:54,194,343...54,206,902
Ensembl chr 2:54,195,739...54,206,846

G

caspase 4

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092

G

catalase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

carbonyl reductase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393

G

coiled-coil domain containing 200

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:86,517,704...86,523,106
Ensembl chr10:86,517,683...86,523,038

G

coiled-coil domain containing 80

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr11:55,685,165...55,718,827
Ensembl chr11:55,685,872...55,719,137

G

C-C motif chemokine ligand 2

severity

protein:increased expression:serum:
CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma (human)
protein:increased expression:serum (human)

CTD
RGD

PMID:31986264 PMID:32416070 PMID:32696007 PMID:31986264 PMID:32360286 More...

RGD:30296676, RGD:38501088, RGD:30309212, RGD:30309209, RGD:30309200

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 20

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629

G

C-C motif chemokine ligand 27

severity

protein:increased expression:plasma (human)

RGD

NCBI chr 5:56,941,402...56,948,511
Ensembl chr 5:56,941,402...56,948,506

G

C-C motif chemokine ligand 3

severity

protein:increased expression:plasma (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:31986264 PMID:32360286 PMID:31986264

RGD:30309209, RGD:30309212

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

G

C-C motif chemokine ligand 4

severity

protein:increased expression:plasma (human)

RGD

PMID:32360286 PMID:32696007 PMID:31986264

RGD:30309209, RGD:38501088, RGD:30309212

NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231

G

C-C motif chemokine ligand 5

severity

protein:increased expression:serum (human)

RGD

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

C-C motif chemokine ligand 7

severity

protein:increased expression:plasma (human)
mRNA:increased expression:bronchoalveolar lavage (human)

PMID:32407669 PMID:32360286

RGD:30296672, RGD:30309209

NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303

G

cellular communication network factor 3

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019

G

cyclin A2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577

G

cyclin B1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172

G

cyclin B2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874

G

C-C motif chemokine receptor 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 8:123,556,286...123,561,841

G

C-C motif chemokine receptor 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100

G

C-C motif chemokine receptor 3

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990

G

C-C motif chemokine receptor 7

mRNA:decreased expression:CD4+ T cells (human)

NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309

G

C-C motif chemokine receptor 9

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:123,396,157...123,410,199
Ensembl chr 8:123,395,813...123,413,969

G

C-C motif chemokine receptor like 2

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 8:111,034,279...111,036,914
Ensembl chr 8:111,034,279...111,036,664

G

chaperonin containing TCP1 subunit 5

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930

G

chaperonin containing TCP1 subunit 8

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079

G

CD163 molecule

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878

G

CD180 molecule

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:33,855,940...33,870,046
Ensembl chr 2:33,855,991...33,899,936

G

CD209d molecule

CTD Direct Evidence: marker/mechanism

NCBI chr12:1,891,109...1,897,559
Ensembl chr12:1,891,113...1,901,171

G

Cd247 molecule

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr13:78,043,302...78,118,437
Ensembl chr13:78,043,307...78,122,263

G

CD2-associated protein

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 9:18,086,744...18,182,744
Ensembl chr 9:18,086,984...18,182,199

G

Cd4 molecule

severity

protein:decreased expression:blood, T cell (human)
protein:decreased expression:serum, lung, T cell (human)

RGD

PMID:32364527 PMID:32427582

RGD:27226699, RGD:30309200

NCBI chr 4:157,668,878...157,695,366

G

Cd68 molecule

mRNA:decreased expression:dendritic cells (human)

NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697

G

CD79a molecule

mRNA:decreased expression:antibody secreting B cells (human)

NCBI chr 1:80,493,581...80,497,936
Ensembl chr 1:80,493,581...80,497,935

G

CD8 subunit alpha

severity
exacerbates

protein:decreased expression:serum, lung, T cell (human)
protein:increased expression:blood, T cell (mouse)
mRNA:increased expression:epithelium of nasopharynx (human)

RGD

PMID:32427582 PMID:32991819 PMID:32898168

RGD:30309200, RGD:124715452, RGD:124715451

NCBI chr 4:103,365,804...103,370,041
Ensembl chr 4:103,365,804...103,370,040

G

cell division cycle 20

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512

G

cell division cycle 25A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701

G

CDC42 binding protein kinase alpha

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:91,683,775...91,903,732
Ensembl chr13:91,684,007...91,903,732

G

cell division cycle 45

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619

G

cell division cycle 6

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011

G

cell division cycle associated 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611

G

cell division cycle associated 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799

G

cell division cycle associated 5

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023

G

cell division cycle associated 8

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629

G

cadherin-related family member 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr16:12,843,436...12,863,321
Ensembl chr16:12,843,437...12,863,396

G

cadherin-related family member 3

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:49,641,833...49,702,016
Ensembl chr 6:49,641,813...49,702,017

G

cyclin-dependent kinase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cyclin-dependent kinase 5

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112

G

cyclin-dependent kinase inhibitor 1C

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048

G

cyclin-dependent kinase inhibitor 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945

G

CCAAT/enhancer binding protein alpha

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412

G

centromere protein F

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669

G

centromere protein U

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr16:45,715,821...45,739,038
Ensembl chr16:45,714,294...45,738,823

G

centromere protein W

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:27,525,324...27,530,464
Ensembl chr 1:27,525,324...27,530,464

G

centrosomal protein 126

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:5,200,576...5,267,740
Ensembl chr 8:5,218,509...5,267,467

G

centrosomal protein 55

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394

G

centrosomal protein 78

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:213,246,183...213,275,275
Ensembl chr 1:213,246,187...213,275,181

G

ceramide synthase 6

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:53,630,637...53,879,692
Ensembl chr 3:53,630,959...53,876,848

G

carboxylesterase 1D

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035

G

complement factor H

severity

DNA:SNP: :

RGD

NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838

G

chitinase 3 like 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787

G

cysteine-rich hydrophobic domain 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr X:68,362,014...68,406,155
Ensembl chr X:68,361,969...68,437,887

G

charged multivesicular body protein 5

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 5:56,081,385...56,098,529
Ensembl chr 5:56,081,343...56,098,529

G

cholinergic receptor nicotinic alpha 7 subunit

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240

G

carbohydrate sulfotransferase 13

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:122,824,022...122,837,940
Ensembl chr 4:122,824,022...122,838,019

G

corepressor interacting with RBPJ, 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 3:58,158,923...58,188,799
Ensembl chr 3:58,158,951...58,188,789

G

citron rho-interacting serine/threonine kinase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr12:40,603,073...40,764,846
Ensembl chr12:40,605,563...40,763,860

G

CDC28 protein kinase regulatory subunit 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr17:13,570,611...13,575,770

G

cardiotrophin-like cytokine factor 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605

G

chloride voltage-gated channel 4

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr X:23,729,194...23,795,391
Ensembl chr X:23,729,338...23,793,238

G

claudin 7

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:54,689,684...54,692,177
Ensembl chr10:54,689,987...54,692,171

G

claudin domain containing 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:93,848,533...93,851,693
Ensembl chr 1:93,848,533...93,851,217

G

C-type lectin domain family 12, member A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:162,798,125...162,816,757
Ensembl chr 4:162,798,125...162,816,753

G

C-type lectin domain family 12, member B

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:162,827,462...162,843,821
Ensembl chr 4:162,827,462...162,838,946

G

C-type lectin domain family 1, member B

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:162,847,978...162,856,291
Ensembl chr 4:162,848,010...162,856,291

G

claspin

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034

G

clathrin, light chain A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472

G

CKLF-like MARVEL transmembrane domain containing 2B

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr19:640,838...651,872
Ensembl chr19:640,824...651,939

G

collagen type XVIII alpha 1 chain

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593

G

collagen type VI alpha 2 chain

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564

G

collagen beta(1-O)galactosyltransferase 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr13:64,523,641...64,628,295
Ensembl chr13:64,523,658...64,627,549

G

COMM domain containing 9

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:88,175,909...88,190,427
Ensembl chr 3:88,175,987...88,190,439

G

COPI coat complex subunit beta 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:99,161,324...99,183,452
Ensembl chr 8:99,161,350...99,185,197

G

coenzyme Q5, methyltransferase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr12:41,316,922...41,333,855
Ensembl chr12:41,316,748...41,333,848

G

coronin 2B

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:62,906,861...63,017,295
Ensembl chr 8:62,906,867...63,017,302

G

coronin 6

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr10:62,311,552...62,319,659
Ensembl chr10:62,311,660...62,319,659

G

cytochrome c oxidase subunit 5A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781

G

carboxypeptidase A3

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:102,712,483...102,744,219
Ensembl chr 2:102,712,589...102,744,203

G

cellular repressor of E1A-stimulated genes 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308

G

cysteine-rich protein 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065

G

ciliary rootlet coiled-coil, rootletin family member 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:93,708,786...93,769,617
Ensembl chr 9:93,708,684...93,769,402

G

C-reactive protein

severity
disease_progression

protein:increased expression:serum (human)
CTD Direct Evidence: marker/mechanism
associated with hyperglycemia;protein:increased expression:serum (human)
associated with cardiovascular system disease;protein:increased expression:blood (human)
protein:increased expression:plasma (human)
associated with diabetes mellitus

CTD
RGD

PMID:32534021 PMID:32125452 PMID:32406594 PMID:32434211 PMID:32456948 More...

RGD:27095965, RGD:32698682, RGD:30310238, RGD:30309957, RGD:30310230, RGD:30310235, RGD:30310229, RGD:30309200, RGD:30296681, RGD:30296673, RGD:27226695

NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178

G

cryptochrome circadian regulator 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091

G

crystallin beta-gamma domain containing 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:146,286,406...146,318,417
Ensembl chr 5:146,286,925...146,323,666

G

colony stimulating factor 1

severity

protein:increased expression:plasma (human)

RGD

PMID:32360286 PMID:32696007

RGD:30309209, RGD:38501088

NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704

G

colony stimulating factor 2

severity

protein:increased expression:plasma (human)

RGD

NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199

G

colony stimulating factor 3

severity

protein:increased expression:plasma (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:31986264 PMID:32360286 PMID:31986264

RGD:30309209, RGD:30309212

NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603

G

cysteine and serine rich nuclear protein 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183

G

cystatin F

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:139,396,830...139,405,557
Ensembl chr 3:139,396,850...139,405,557

G

catenin delta 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516

G

cathepsin B

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500

G

cathepsin D

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488

G

cathepsin L

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548

G

cathepsin Z

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:163,224,875...163,235,645
Ensembl chr 3:163,224,875...163,235,645

G

C-X-C motif chemokine ligand 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215

G

C-X-C motif chemokine ligand 10

severity

CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma (human)

CTD
RGD

PMID:31986264 PMID:32427582 PMID:32696007 PMID:31986264 PMID:32360286

RGD:30309200, RGD:38501088, RGD:30309212, RGD:30309209

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

G

C-X-C motif chemokine ligand 11

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271

G

C-X-C motif chemokine ligand 16

protein:increased expression:serum:

RGD

NCBI chr10:55,166,721...55,171,316
Ensembl chr10:55,166,723...55,171,592

G

C-X-C motif chemokine ligand 17

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 1:80,984,751...80,996,842
Ensembl chr 1:80,984,964...80,996,726

G

C-X-C motif chemokine ligand 2

protein:increased expression:serum:

RGD

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

G

C-X-C motif chemokine ligand 3

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511

G

C-X-C motif chemokine ligand 6

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093

G

C-X-C motif chemokine ligand 9

severity

protein:increased expression:serum:
protein:increased expression:plasma (human)

RGD

PMID:32416070 PMID:32696007 PMID:32360286

RGD:30296676, RGD:38501088, RGD:30309209

NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435

G

C-X-C motif chemokine receptor 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 9:75,766,894...75,771,079
Ensembl chr 9:75,766,770...75,771,084

G

C-X-C motif chemokine receptor 2

mRNA:increased expression:bronchoalveolar lavage (human)
mRNA:decreased expression:peripheral blood mononuclear cell (human)

PMID:32228226 PMID:32407669

RGD:28912744 RGD:30296672

NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425

G

C-X-C motif chemokine receptor 4

mRNA:decreased expression:memory B cells (human)

NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883

G

cytochrome b reductase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:55,934,874...55,962,132
Ensembl chr 3:55,934,874...55,962,108

G

cytoplasmic FMR1 interacting protein 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:106,710,924...106,799,393
Ensembl chr 1:106,711,016...106,799,386

G

dual adaptor of phosphotyrosine and 3-phosphoinositides 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 2:226,425,890...226,475,445
Ensembl chr 2:226,425,898...226,475,423

G

DNA-damage-inducible transcript 4

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105

G

DENN domain containing 1B

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr13:50,545,324...50,772,922
Ensembl chr13:50,545,836...50,770,601

G

DEP domain containing 1B

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:39,891,163...39,963,779
Ensembl chr 2:39,891,481...39,963,779

G

DEPP autophagy regulator 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542

G

deoxyribose-phosphate aldolase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:170,663,689...170,742,469
Ensembl chr 4:170,663,665...170,758,865

G

24-dehydrocholesterol reductase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137

G

dehydrogenase/reductase 4

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127

G

DLG associated protein 5

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518

G

dedicator of cyto-kinesis 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:189,467,143...189,983,777
Ensembl chr 1:189,467,143...189,983,768

G

dihydropyrimidine dehydrogenase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982

G

dorsal inhibitory axon guidance protein

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:158,530,149...158,563,457
Ensembl chr 5:158,530,342...158,564,483

G

denticleless E3 ubiquitin protein ligase homolog

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890

G

dual specificity phosphatase 1

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr10:16,680,478...16,683,275

G

dual specificity phosphatase 2

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499

G

dual specificity phosphatase 7

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:107,009,369...107,016,404
Ensembl chr 8:107,008,528...107,016,404

G

dynein light chain LC8-type 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr12:41,312,365...41,316,157
Ensembl chr12:41,312,367...41,314,741

G

E2F transcription factor 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361

G

E2F transcription factor 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217

G

ELL associated factor 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr11:63,960,200...64,004,610
Ensembl chr11:63,960,200...64,004,610

G

EBF family member 4

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:117,498,186...117,566,566
Ensembl chr 3:117,498,319...117,566,566

G

enoyl CoA hydratase domain containing 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr17:72,070,697...72,093,519
Ensembl chr17:72,070,668...72,093,516

G

eukaryotic translation elongation factor 1 alpha 1

mRNA:decreased expression:antibody secreting B cells (human)

NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839

G

eukaryotic translation elongation factor 2

mRNA:decreased expression:antibody secreting B cells (human)

NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183

G

EF-hand calcium binding domain 2

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr13:90,152,002...90,237,918
Ensembl chr13:90,152,185...90,238,218

G

ephrin A5

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:102,316,753...102,595,480
Ensembl chr 9:102,320,295...102,597,413

G

early growth response 3

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627

G

eukaryotic translation initiation factor 4E family member 3

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 4:132,258,502...132,301,808
Ensembl chr 4:132,258,502...132,301,808

G

eukaryotic translation initiation factor 4 gamma 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941

G

elastase, neutrophil expressed

protein:increased expression:plasma (human)

RGD

NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100

G

E74 like ETS transcription factor 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr15:54,890,644...54,986,721
Ensembl chr15:54,865,616...54,986,699

G

elongation factor for RNA polymerase II 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781

G

enolase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336

G

ectonucleotide pyrophosphatase/phosphodiesterase 3

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:20,563,700...20,635,044
Ensembl chr 1:20,563,697...20,635,041

G

ectonucleotide pyrophosphatase/phosphodiesterase family member 5

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:16,910,187...16,917,633
Ensembl chr 9:16,910,831...16,917,480

G

Eph receptor B1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:102,507,549...102,944,839
Ensembl chr 8:102,507,549...102,944,839

G

Eph receptor B2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059

G

EGFR pathway substrate 8, signaling adaptor

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873

G

epithelial stromal interaction 1

mRNA:increased expression:bronchoalveolar lavage (human)
mRNA:increased expression:peripheral blood mononuclear cell (human)

PMID:32228226 PMID:32407669

RGD:28912744 RGD:30296672

NCBI chr15:53,283,964...53,382,192
Ensembl chr15:53,284,216...53,382,191

G

Era-like 12S mitochondrial rRNA chaperone 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:62,961,725...62,968,747
Ensembl chr10:62,961,730...62,968,994

G

ERI1 exoribonuclease family member 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:174,140,831...174,168,757
Ensembl chr 1:174,141,993...174,168,665

G

ER lipid raft associated 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394

G

extra spindle pole bodies like 1, separase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984

G

estrogen receptor 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919

G

epithelial splicing regulatory protein 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr19:34,034,559...34,041,726
Ensembl chr19:34,034,559...34,041,726

G

exonuclease 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362

G

coagulation factor II, thrombin

severity
disease_progression

associated with diabetes mellitus

RGD

PMID:32198776 PMID:32350161 PMID:32345579 PMID:32302954

RGD:30296673, RGD:30309962, RGD:30296681, RGD:30296679

NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486

G

coagulation factor III, tissue factor

severity

DNA:SNP: : (rs72729504) (human)

RGD

PMID:32198776 PMID:32747830

RGD:30296673, RGD:38500238

NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668

G

coagulation factor V

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:76,513,509...76,583,106
Ensembl chr13:76,513,255...76,582,317

G

coagulation factor VIII

CTD Direct Evidence: marker/mechanism

NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857

G

fatty acid desaturase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734

G

fumarylacetoacetate hydrolase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505

G

family with sequence similarity 131, member B

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:71,201,037...71,210,292
Ensembl chr 4:71,201,038...71,210,228

G

family with sequence similarity 169, member A

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:28,384,162...28,441,361
Ensembl chr 2:28,383,784...28,438,910

G

FAM20C, golgi associated secretory pathway kinase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543

G

family with sequence similarity 72, member A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:42,967,701...42,979,083
Ensembl chr13:42,967,578...42,984,208

G

family with sequence similarity 89, member A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr19:52,710,002...52,722,630
Ensembl chr19:52,710,019...52,722,631

G

Fc mu receptor

mRNA:decreased expression:memory B cells (human)

NCBI chr13:42,337,363...42,351,706
Ensembl chr13:42,337,414...42,351,653

G

Fc receptor-like 5

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:172,881,763...172,912,912
Ensembl chr 2:172,881,448...172,913,148

G

Fc receptor-like 6

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr13:85,062,709...85,072,308
Ensembl chr13:85,066,694...85,072,600

G

fer-1-like family member 4

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:144,536,099...144,571,634
Ensembl chr 3:144,536,099...144,571,634

G

FYVE, RhoGEF and PH domain containing 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr20:7,424,795...7,441,603
Ensembl chr20:7,424,790...7,441,603

G

fibroblast growth factor 2

severity

protein:increased expression:plasma (human)

RGD

NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221

G

fibroblast growth factor receptor-like 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr14:1,009,863...1,022,620
Ensembl chr14:1,009,786...1,021,928

G

fibrinogen-like 2

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207

G

fumarate hydratase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266

G

FHF complex subunit HOOK interacting protein 1A

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:171,016,951...171,265,715
Ensembl chr 2:171,021,246...171,265,848

G

FKBP prolyl isomerase 5

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674

G

FKBP prolyl isomerase 9

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:86,106,256...86,156,723
Ensembl chr 4:86,106,282...86,156,721

G

Fms related receptor tyrosine kinase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626

G

Fms related receptor tyrosine kinase 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr12:7,623,930...7,699,474
Ensembl chr12:7,623,930...7,699,474

G

FLVCR choline and putative heme transporter 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:105,408,355...105,472,355
Ensembl chr 6:105,408,339...105,472,353

G

fragile X messenger ribonucleoprotein 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr X:147,240,239...147,278,057
Ensembl chr X:147,240,301...147,278,050

G

fibronectin 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

G

FosB proto-oncogene, AP-1 transcription factor subunit

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465

G

forkhead box N2

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 6:6,018,653...6,065,226
Ensembl chr 6:6,018,879...6,064,278

G

formyl peptide receptor 3

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 1:58,884,427...58,893,472
Ensembl chr 1:58,845,118...58,893,467

G

ferric-chelate reductase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:204,820,898...204,881,487
Ensembl chr 2:204,823,025...204,895,540

G

ferritin heavy chain 1

severity

protein:increased expression:serum (human)
associated with hyperglycemia;protein:increased expression:serum (human)

RGD

PMID:32365221 PMID:32406594

RGD:30310229, RGD:32698682

NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424

G

ferritin light chain 1

severity

protein:increased expression:serum (human)
associated with hyperglycemia;protein:increased expression:serum (human)

RGD

PMID:32365221 PMID:32406594

RGD:30310229, RGD:32698682

NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725

G

alpha-L-fucosidase 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:7,885,986...7,900,777
Ensembl chr 1:7,885,918...7,900,776

G

fucosyltransferase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 1:96,119,549...96,139,567
Ensembl chr 1:96,119,371...96,140,360

G

frizzled class receptor 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334

G

frizzled class receptor 5

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:66,113,096...66,120,276
Ensembl chr 9:66,113,112...66,121,457

G

G0/G1switch 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451

G

glucose 6 phosphatase catalytic subunit 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:87,146,987...87,151,223
Ensembl chr10:87,146,901...87,151,221

G

alpha glucosidase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:104,529,673...104,546,836
Ensembl chr10:104,529,747...104,546,836

G

GABA type A receptor associated protein like 1

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450

G

growth arrest and DNA-damage-inducible, beta

mRNA:increased expression:bronchoalveolar lavage (human)
mRNA:increased expression:CD14++ monocytes (human)

PMID:32377375 PMID:32407669

RGD:30296672 RGD:32716422

NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046

G

galactokinase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:101,243,146...101,247,323
Ensembl chr10:101,235,994...101,247,337

G

polypeptide N-acetylgalactosaminyltransferase 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr19:52,213,226...52,324,816
Ensembl chr19:52,213,351...52,324,813

G

glyceraldehyde-3-phosphate dehydrogenase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235

G

growth arrest-specific 2 like 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:23,803,578...23,836,816
Ensembl chr 7:23,806,310...23,836,411

G

golgi associated kinase 1B

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477

G

GATA binding protein 3

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391

G

globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:11,826,131...11,829,745

G

GTP cyclohydrolase 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698

G

growth differentiation factor 11

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:1,311,732...1,325,211
Ensembl chr 7:1,311,732...1,320,725

G

glial fibrillary acidic protein

disease_progression

protein:increased expression:plasma (human)
protein:increased expression:serum (human)

RGD

PMID:32546655 PMID:33743046

RGD:127284882, RGD:127284892

NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589

G

gamma-glutamyl hydrolase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787

G

GTPase, IMAP family member 4

mRNA:decreased expression:CD4+ T cells (human)

NCBI chr 4:77,636,401...77,643,315
Ensembl chr 4:77,636,401...77,643,306

G

GTPase, IMAP family member 7

mRNA:decreased expression:CD4+ T cells (human)

NCBI chr 4:77,670,522...77,674,692
Ensembl chr 4:77,670,367...77,675,272

G

glycine decarboxylase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:227,883,249...227,962,119
Ensembl chr 1:227,883,249...227,962,097

G

gliomedin

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:54,679,015...54,723,198
Ensembl chr 8:54,679,119...54,723,196

G

GLI family zinc finger 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251

G

glycosylated lysosomal membrane protein

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:173,794,273...173,797,863
Ensembl chr 2:173,794,255...173,799,960

G

glutaredoxin

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680

G

glucosamine-6-phosphate deaminase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr18:30,165,435...30,177,462
Ensembl chr18:30,165,427...30,177,486

G

golgi membrane protein 1

RGD

NCBI chr17:4,995,925...5,044,329
Ensembl chr17:4,996,104...5,034,057

G

glycerol-3-phosphate dehydrogenase 2

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901

G

G protein-coupled estrogen receptor 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889

G

glycoprotein nmb

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367

G

G protein-coupled receptor 68

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089

G

glutathione peroxidase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

growth factor receptor bound protein 10

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806

G

glyoxylate and hydroxypyruvate reductase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:59,234,179...59,243,614
Ensembl chr 5:59,234,192...59,243,603

G

glutathione S-transferase mu 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase mu 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961

G

glutathione S-transferase omega 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468

G

glutathione S-transferase theta 1

severity

DNA:deletion:

RGD

NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585

G

glutathione S-transferase zeta 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284

G

G-2 and S-phase expressed 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806

G

granzyme B

protein:increased expression:plasma (human)

RGD

NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814

G

H1.0 linker histone

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694

G

H1.10 linker histone

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:120,440,515...120,441,578
Ensembl chr 4:120,440,870...120,441,448

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869

G

HMG-box transcription factor 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787

G

holocytochrome c synthase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr X:24,932,943...24,942,376
Ensembl chr X:24,933,002...24,942,366

G

HCK proto-oncogene, Src family tyrosine kinase

CTD Direct Evidence: marker/mechanism

NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693

G

high density lipoprotein binding protein

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:93,948,099...94,018,040
Ensembl chr 9:93,949,913...94,018,048

G

HEAT repeat containing 4

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:103,574,360...103,611,578
Ensembl chr 6:103,574,366...103,612,100

G

heme binding protein 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:167,974,316...168,003,854
Ensembl chr 4:167,974,319...168,003,854

G

hexosaminidase subunit beta

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223

G

hepatocyte growth factor

severity

protein:increased expression:plasma (human)
mRNA:increased expression:peripheral blood mononuclear cell (human)

PMID:32228226 PMID:32360286

RGD:28912744, RGD:30309209

NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409

G

Holliday junction recognition protein

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728

G

hexokinase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131

G

hyaluronan-mediated motility receptor

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060

G

haptoglobin

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523

G

histamine receptor H4

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr18:4,166,270...4,182,426
Ensembl chr18:4,166,270...4,246,345

G

hydroxysteroid (17-beta) dehydrogenase 10

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr X:21,089,142...21,091,603
Ensembl chr X:21,089,122...21,109,488

G

hydroxysteroid (17-beta) dehydrogenase 4

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952

G

HtrA serine peptidase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379

G

hydrogen voltage-gated channel 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr12:34,341,673...34,370,010
Ensembl chr12:34,335,190...34,370,141

G

intercellular adhesion molecule 5

CTD Direct Evidence: marker/mechanism

NCBI chr 8:19,567,390...19,575,588
Ensembl chr 8:19,568,600...19,575,588

G

isocitrate dehydrogenase (NADP(+)) 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708

G

immediate early response 2

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211

G

immediate early response 3

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583

G

interferon, alpha-inducible protein 27 like 2B

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:122,598,872...122,600,358
Ensembl chr 6:122,598,872...122,600,360

G

interferon-induced protein 44

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844

G

interferon induced with helicase C domain 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456

G

interferon-induced protein with tetratricopeptide repeats 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 1:232,152,038...232,154,103
Ensembl chr 1:232,127,170...232,154,435

G

interferon-induced protein with tetratricopeptide repeats 2

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635

G

interferon-induced protein with tetratricopeptide repeats 3

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307

G

interferon induced transmembrane protein 2

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741

G

interferon induced transmembrane protein 3

severity

DNA:SNP: (rs12252)(human)
mRNA:increased expression:bronchoalveolar lavage (human)

PMID:32407669 PMID:32348495

RGD:30296672, RGD:30296684

NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203

G

interferon alpha and beta receptor subunit 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr11:30,725,774...30,752,227
Ensembl chr11:30,725,790...30,749,979

G

interferon alpha and beta receptor subunit 2

CTD Direct Evidence: marker/mechanism

NCBI chr11:30,613,576...30,645,958
Ensembl chr11:30,613,767...30,668,124

G

interferon beta 1

treatment

RGD

NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523

G

interferon gamma

severity

protein:increased expression:plasma (human)

RGD

PMID:31986264 PMID:32696007

RGD:30309212, RGD:38501088

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

interferon gamma receptor 2

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005

G

interferon, lambda 1

ameliorates

human protein in a mouse model

RGD

NCBI chr 1:83,798,651...83,800,297
Ensembl chr 1:83,798,703...83,800,235

G

intraflagellar transport associated protein

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:87,812,068...87,906,517
Ensembl chr 3:87,817,408...87,906,547

G

insulin-like growth factor binding protein 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937

G

insulin-like growth factor binding protein 3

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083

G

gamma-2a immunoglobulin heavy chain

mRNA:increased expression:peripheral blood mononuclear cell (human)

G

immunoglobulin heavy chain 6, pseudogene 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:136,154,202...136,187,939
Ensembl chr 6:136,187,348...136,187,728
Ensembl chr 6:136,187,348...136,187,728

G

immunoglobulin heavy constant gamma 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

Ensembl chr 6:132,389,370...132,393,397

G

immunoglobulin heavy chain like 7

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:134,584,503...134,585,017
Ensembl chr 6:134,584,503...134,585,002
Ensembl chr 6:134,584,503...134,585,002

G

immunoglobulin heavy variable 3-72 like 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:134,328,070...134,328,632
Ensembl chr 6:134,328,064...134,358,517
Ensembl chr 6:134,328,064...134,358,517

G

immunoglobulin kappa constant

mRNA:increased expression:peripheral blood mononuclear cell (human)

G

immunoglobulin kappa chain variable 8-30 like 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:101,838,285...101,839,132

G

immunoglobulin kappa variable like, pseudogene 13

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:96,968,574...96,969,477

G

immunoglobulin lambda-like polypeptide 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr11:84,138,847...84,142,238
Ensembl chr11:84,138,910...84,142,216

G

IKAROS family zinc finger 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:71,046,038...71,191,296
Ensembl chr 9:71,042,440...71,190,867

G

interleukin 10

severity

protein:increased expression:plasma (human)
CTD Direct Evidence: marker/mechanism
associated with cardiovascular system disease;protein:increased expression:blood (human)
protein:increased expression:serum (human)

CTD
RGD

PMID:31986264 PMID:32161940 PMID:31986264 PMID:32696007 PMID:32456948 More...

RGD:30309212, RGD:38501088, RGD:30309957, RGD:30310229

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 10 receptor subunit alpha

mRNA:decreased expression:bronchoalveolar lavage (human)

NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061

G

interleukin 10 receptor subunit beta

CTD Direct Evidence: marker/mechanism

NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074

G

interleukin 13

severity

protein:increased expression:plasma (human)

RGD

PMID:32360286 PMID:31986264

RGD:30309209, RGD:30309212

NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737

G

interleukin 17A

severity

protein:increased expression:plasma (human)

RGD

NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889

G

interleukin 18

severity

protein:increased expression:plasma (human)

RGD

PMID:32360286 PMID:32696007

RGD:30309209, RGD:38501088

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 1 beta

severity

protein:increased expression:plasma (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:32171193 PMID:31986264

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 1 receptor type 1

severity

protein:increased expression:serum:
protein:increased expression:plasma (human)

RGD

PMID:32416070 PMID:31986264 PMID:32360286

RGD:30296676, RGD:30309212, RGD:30309209

NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937

G

interleukin 1 receptor antagonist

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445

G

interleukin 2

severity

protein:increased expression:plasma (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:31986264 PMID:31986264 PMID:32696007

RGD:30309212, RGD:38501088

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 2 receptor subunit alpha

severity

protein:increased expression:serum (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:32026671 PMID:32161940 PMID:32365221 PMID:32164089 PMID:32297828

RGD:30310229, RGD:36049814, RGD:32716368

NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697

G

interleukin 2 receptor subunit beta

severity

protein:increased expression:serum (human)

RGD

NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054

G

interleukin 2 receptor subunit gamma

severity

protein:increased expression:serum (human)

RGD

NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823

G

interleukin 4

severity

protein:increased expression:plasma (human)

RGD

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

G

interleukin 4 receptor

mRNA:decreased expression:bronchoalveolar lavage (human)

NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980

G

interleukin 5 receptor subunit alpha

mRNA:decreased expression:peripheral blood mononuclear cell (human)
mRNA:increased expression:bronchoalveolar lavage (human)

PMID:32228226 PMID:32407669

RGD:28912744 RGD:30296672

NCBI chr 4:139,630,652...139,664,593
Ensembl chr 4:139,632,066...139,668,544

G

interleukin 6

severity
disease_progression

protein:increased expression:serum (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma (human)
associated with cardiovascular system disease;protein:increased expression:blood (human)
associated with diabetes mellitus
protein:increased expression:serum:

CTD
RGD

PMID:32026671 PMID:32161940 PMID:32171193 PMID:32534021 PMID:32125452 More...

RGD:27095965, RGD:38501088, RGD:36049814, RGD:32716368, RGD:30310238, RGD:30309957, RGD:30310230, RGD:30310229, RGD:30309212, RGD:30309206, RGD:30309200, RGD:30296681, RGD:30296676, RGD:27226695

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

interleukin 7

severity

protein:increased expression:plasma (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:31986264 PMID:31986264

NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075

G

interleukin 7 receptor

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757

G

interleukin 9

severity

protein:increased expression:plasma (human)

RGD

NCBI chr17:8,111,772...8,114,895
Ensembl chr17:8,111,772...8,114,895

G

inka box actin regulator 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:108,674,263...108,675,953
Ensembl chr 8:108,674,263...108,675,953

G

interferon regulatory factor 2

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr16:45,439,215...45,550,054
Ensembl chr16:45,439,225...45,550,024

G

interferon regulatory factor 4

mRNA:decreased expression:antibody secreting B cells (human)

NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070

G

interferon regulatory factor 5

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267

G

interferon regulatory factor 7

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832

G

ISG15 ubiquitin-like modifier

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435

G

integrin subunit alpha 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:46,646,125...46,812,237
Ensembl chr 2:46,653,193...46,812,238

G

integrin subunit alpha 7

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:1,360,125...1,388,886
Ensembl chr 7:1,359,940...1,388,450

G

integrin subunit beta 8

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:140,125,002...140,208,261
Ensembl chr 6:140,127,203...140,208,476

G

integral membrane protein 2A

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr X:72,486,383...72,492,344
Ensembl chr X:72,486,381...72,492,363

G

intersectin 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr11:30,978,590...31,160,645
Ensembl chr11:30,978,590...31,160,645

G

Janus kinase 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

G

joining chain of multimeric IgA and IgM

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr14:19,538,927...19,547,023
Ensembl chr14:19,538,952...19,546,298

G

junctophilin 4

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr15:28,579,579...28,588,903
Ensembl chr15:28,571,568...28,587,573

G

Jun proto-oncogene, AP-1 transcription factor subunit

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

KN motif and ankyrin repeat domains 3

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:14,594,358...14,607,675
Ensembl chr 7:14,594,422...14,607,675

G

potassium voltage-gated channel subfamily E regulatory subunit 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901

G

potassium two pore domain channel subfamily K member 13

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:119,240,825...119,345,292
Ensembl chr 6:119,242,188...119,345,240

G

potassium calcium-activated channel subfamily M alpha 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr15:302,480...1,007,675
Ensembl chr15:302,214...1,001,198

G

potassium voltage-gated channel subfamily Q member 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669

G

potassium channel tetramerization domain containing 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:100,510,193...100,548,765
Ensembl chr13:100,510,195...100,548,718

G

KIAA0930 homolog

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:116,067,974...116,107,678
Ensembl chr 7:116,071,447...116,107,727

G

KIAA1958 homolog

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:74,491,762...74,637,929
Ensembl chr 5:74,491,752...74,632,408

G

kinesin family member 11

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766

G

kinesin family member 14

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:47,926,975...47,990,598
Ensembl chr13:47,927,044...47,989,164

G

kinesin family member 15

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:122,601,888...122,672,750
Ensembl chr 8:122,601,897...122,672,750

G

kinesin family member 18B

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:87,870,424...87,889,895
Ensembl chr10:87,870,428...87,889,850

G

kinesin family member 20A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780

G

kinesin family member 21A

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:122,062,523...122,179,051
Ensembl chr 7:122,062,537...122,178,999

G

kinesin family member 23

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072

G

kinesin family member 2C

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637

G

kinesin family member 3a

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr10:37,725,930...37,761,183
Ensembl chr10:37,725,970...37,759,191

G

kinesin family member 4A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr X:65,721,746...65,824,277
Ensembl chr X:65,721,779...65,824,139

G

kinesin family member C1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105

G

killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:69,715,529...69,754,050
Ensembl chr 1:69,715,535...69,754,050

G

KLF transcription factor 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944

G

KLF transcription factor 4

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602

G

KLF transcription factor 6

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570

G

killer cell lectin like receptor B1A

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:161,890,577...161,904,050
Ensembl chr 4:161,890,577...161,961,675

G

killer cell lectin like receptor G1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:155,455,465...155,467,301
Ensembl chr 4:155,455,495...155,467,424

G

kinetochore scaffold 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:106,029,627...106,091,915
Ensembl chr 3:106,029,661...106,091,915

G

kinetochore-localized astrin/SPAG5 binding protein

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:105,800,762...105,820,555
Ensembl chr 3:105,800,954...105,820,715

G

kaptin (actin binding protein)

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:76,808,737...76,809,531

G

kyphoscoliosis peptidase

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:103,086,959...103,126,305
Ensembl chr 8:103,086,630...103,126,024

G

leukocyte-associated immunoglobulin-like receptor 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:70,068,571...70,187,851
Ensembl chr 1:70,157,681...70,185,807

G

laminin subunit alpha 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:17,672,675...18,320,641
Ensembl chr 1:17,672,536...18,320,530

G

laminin subunit gamma 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492

G

leucine aminopeptidase 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr14:65,608,375...65,627,359
Ensembl chr14:65,608,376...65,627,359

G

lipocalin 2

protein:increased expression:plasma (human)

RGD

NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095

G

lactate dehydrogenase A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472

G

low density lipoprotein receptor

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580

G

galectin 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345

G

galectin 3

severity

mRNA:increased expression:peripheral blood mononuclear cell (human)

PMID:32228226 PMID:35115644

RGD:28912744, RGD:151356744

NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025

G

leucine-rich repeat-containing G protein-coupled receptor 6

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr13:46,424,382...46,544,074
Ensembl chr13:46,424,383...46,543,945

G

LHFPL tetraspan subfamily member 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:25,281,771...25,428,128
Ensembl chr 2:25,281,901...25,427,950

G

leukocyte immunoglobulin like receptor B3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:69,928,948...69,939,461
Ensembl chr 1:69,928,945...69,939,048

G

lens intrinsic membrane protein 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:93,837,597...93,843,769
Ensembl chr 1:93,837,597...93,843,769

G

lipase A, lysosomal acid type

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633

G

LLGL scribble cell polarity complex component 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr10:101,050,978...101,086,527
Ensembl chr10:101,051,408...101,086,525

G

lamin B1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502

G

LIM domain only 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:90,355,234...90,377,970
Ensembl chr 3:90,365,883...90,377,953

G

U4 spliceosomal RNA

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr12:41,126,050...41,126,190
Ensembl chr12:41,126,050...41,126,190

G

U1 spliceosomal RNA

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr18:79,901,335...79,901,477
Ensembl chr18:79,901,335...79,901,477
Ensembl chr18:79,901,335...79,901,477

G

lipoprotein lipase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249

G

leucine rich repeat and fibronectin type III domain containing 3

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:85,616,862...85,623,725
Ensembl chr 1:85,616,868...85,623,725

G

leucine rich repeat containing 43

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr12:33,074,149...33,092,257
Ensembl chr12:33,074,150...33,095,082

G

leukotriene A4 hydrolase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600

G

latent transforming growth factor beta binding protein 4

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:82,600,136...82,634,346
Ensembl chr 1:82,600,136...82,632,178

G

LYN proto-oncogene, Src family tyrosine kinase

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868

G

LysM domain containing 2

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 8:76,378,984...76,394,396
Ensembl chr 8:76,379,219...76,394,654

G

leucine zipper transcription factor-like 1

CTD Direct Evidence: marker/mechanism

PMID:32558485 PMID:32998156

NCBI chr 8:123,344,085...123,360,245
Ensembl chr 8:123,344,925...123,360,192

G

MET transcriptional regulator MACC1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:140,352,690...140,430,255
Ensembl chr 6:140,352,755...140,430,255

G

macrophage immunometabolism regulator

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:98,420,760...98,440,818
Ensembl chr 9:98,420,376...98,441,733

G

MAF bZIP transcription factor B

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031

G

MAF bZIP transcription factor G

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026

G

MAGE family member E1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr X:70,189,242...70,192,789
Ensembl chr X:70,189,187...70,192,810

G

monoamine oxidase A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr X:6,032,172...6,098,308
Ensembl chr X:6,030,795...6,099,593

G

mitogen-activated protein kinase kinase kinase 6

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:145,440,126...145,452,213
Ensembl chr 5:145,440,346...145,452,212

G

mitogen-activated protein kinase 6

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:76,146,650...76,169,767
Ensembl chr 8:76,146,690...76,169,720

G

membrane associated ring-CH-type finger 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr16:23,255,551...24,114,290
Ensembl chr16:23,258,799...24,114,277

G

macrophage receptor with collagenous structure

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:31,616,278...31,648,521
Ensembl chr13:31,616,278...31,648,521

G

MARVEL domain containing 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:240,954,050...240,958,101
Ensembl chr 1:240,954,452...240,958,384

G

microtubule associated tyrosine carboxypeptidase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr19:33,158,053...33,166,784
Ensembl chr19:33,158,056...33,166,445

G

megakaryocyte-associated tyrosine kinase

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:8,456,990...8,465,947
Ensembl chr 7:8,456,998...8,462,022

G

myoglobin

severity

protein:increased expression:serum (human)
associated with hyperglycemia;protein:increased expression:serum (human)

RGD

PMID:32125452 PMID:32406594

RGD:27095965, RGD:32698682

NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383

G

mast cell-expressed membrane protein 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr12:1,721,781...1,727,350
Ensembl chr12:1,718,730...1,725,986

G

MCL1 apoptosis regulator, BCL2 family member

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303

G

minichromosome maintenance 10 replication initiation factor

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr17:73,263,788...73,288,346
Ensembl chr17:73,266,095...73,287,364

G

minichromosome maintenance complex component 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847

G

malic enzyme 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304

G

MER proto-oncogene, tyrosine kinase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554

G

methyltransferase 9, His-X-His N1(pi)-histidine

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:175,575,805...175,623,065
Ensembl chr 1:175,577,890...175,623,061

G

alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:33,563,642...33,582,718
Ensembl chr10:33,561,388...33,591,503

G

alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:39,673,427...39,786,747
Ensembl chr 9:39,673,430...39,766,890

G

mitochondrial genome maintenance exonuclease 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:131,640,770...131,649,933
Ensembl chr 3:131,640,944...131,649,932

G

microsomal glutathione S-transferase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892

G

MIB E3 ubiquitin protein ligase 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:166,243,776...166,259,944
Ensembl chr 5:166,243,776...166,259,650

G

mitochondrial calcium uptake 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr20:27,668,681...27,816,322
Ensembl chr20:27,668,747...27,814,964

G

mast cell immunoglobulin-like receptor 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:91,684,288...91,705,284
Ensembl chr10:91,687,831...91,705,282

G

marker of proliferation Ki-67

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762

G

myeloid leukemia factor 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:151,648,492...151,681,654
Ensembl chr 2:151,648,511...151,681,652

G

membrane metallo-endopeptidase

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792

G

matrix metallopeptidase 1

protein:increased expression:plasma (human)

RGD

NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097

G

matrix metallopeptidase 19

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:1,221,229...1,229,555
Ensembl chr 7:1,221,343...1,229,555

G

matrix metallopeptidase 2

protein:increased expression:plasma (human)

RGD

NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870

G

matrix metallopeptidase 23

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:166,239,643...166,242,734
Ensembl chr 5:166,239,644...166,242,433

G

matrix metallopeptidase 8

protein:increased expression:plasma (human)

RGD

NCBI chr 8:4,724,009...4,733,864
Ensembl chr 8:4,724,029...4,733,520

G

mannose-P-dolichol utilization defect 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:54,374,719...54,380,301
Ensembl chr10:54,374,725...54,380,447

G

MPN domain containing

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:839,473...846,446
Ensembl chr 9:840,143...846,439

G

mannose receptor, C type 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857

G

mitochondrial ribosomal protein L12

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:105,758,410...105,762,913
Ensembl chr10:105,758,410...105,762,913

G

mitochondrial ribosomal protein L15

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:14,729,961...14,741,276
Ensembl chr 5:14,729,979...14,741,276

G

mitochondrial ribosomal protein L37

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:121,827,892...121,846,187
Ensembl chr 5:121,829,111...121,846,176

G

mitochondrial ribosomal protein L51

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:157,991,756...157,994,715
Ensembl chr 4:157,992,408...157,995,414

G

membrane spanning 4-domains A2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:208,440,179...208,448,716
Ensembl chr 1:208,440,361...208,448,310

G

membrane spanning 4-domains A4A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:208,060,507...208,085,121
Ensembl chr 1:208,046,971...208,085,119

G

musculin

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:4,547,335...4,553,206
Ensembl chr 5:4,547,405...4,553,203

G

macrophage scavenger receptor 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr16:52,717,775...52,803,602
Ensembl chr16:52,717,732...52,799,676

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061

G

metallothionein 1, pseudogene 3

mRNA:decreased expression:CD14 monocytes (human)
mRNA:increased expression:peripheral blood mononuclear cell (human)

PMID:32228226 PMID:32377375

RGD:28912744 RGD:32716422

NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135

G

metallothionein 2A

mRNA:decreased expression:CD14 monocytes (human)

NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784

G

mitochondrial carrier 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:76,830,549...76,850,189
Ensembl chr 3:76,830,413...76,850,189

G

mitochondrial transcription termination factor 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:18,598,202...18,608,278
Ensembl chr 7:18,598,103...18,620,684

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608

G

mucin 1, cell surface associated

CTD Direct Evidence: marker/mechanism

NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733

G

murinoglobulin 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:155,164,061...155,236,894
Ensembl chr 4:155,164,011...155,236,475

G

MYB proto-oncogene like 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183

G

MYB proto-oncogene like 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708

G

MYC proto-oncogene, bHLH transcription factor

mRNA:decreased expression:CD4+ T cells (human)

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

G

myeloid-derived growth factor

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:999,659...1,008,804
Ensembl chr 9:1,000,722...1,008,822

G

myosin heavy chain 11

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr10:743,364...838,459
Ensembl chr10:743,685...838,459

G

myosin IE

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:70,887,934...71,080,180
Ensembl chr 8:70,887,870...71,080,169

G

myosin VI

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292

G

myosin VIIA

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:152,342,611...152,414,171
Ensembl chr 1:152,344,448...152,414,157

G

myoferlin

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:235,673,666...235,822,413
Ensembl chr 1:235,673,666...235,822,334

G

marginal zone B and B1 cell-specific protein

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr18:27,238,999...27,241,060
Ensembl chr18:27,239,001...27,241,094

G

alpha-N-acetylgalactosaminidase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:113,846,358...113,855,430
Ensembl chr 7:113,846,374...113,855,315

G

NLR family, apoptosis inhibitory protein 6

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:31,507,423...31,559,098
Ensembl chr 2:31,507,424...31,570,542

G

nicotinamide phosphoribosyltransferase

mRNA:increased expression:bronchoalveolar lavage (human)
mRNA:increased expression:CD14++ monocytes (human)

PMID:32377375 PMID:32407669

RGD:30296672 RGD:32716422

NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100

G

nucleosome assembly protein 1-like 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr X:68,174,051...68,176,449
Ensembl chr X:68,173,987...68,176,666

G

nibrin

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150

G

neurocalcin delta

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:68,532,671...68,964,740
Ensembl chr 7:68,534,421...68,964,496

G

non-SMC condensin I complex, subunit G

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr14:65,403,930...65,432,902
Ensembl chr14:65,404,163...65,432,902

G

non-SMC condensin I complex, subunit H

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:114,371,937...114,399,178
Ensembl chr 3:114,371,941...114,399,180

G

natural cytotoxicity triggering receptor 3

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr20:3,637,242...3,643,748
Ensembl chr20:3,638,240...3,643,799

G

NADH:ubiquinone oxidoreductase complex assembly factor 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:106,639,025...106,650,549
Ensembl chr 3:106,639,851...106,650,212

G

NADH:ubiquinone oxidoreductase complex assembly factor 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:109,261,362...109,263,194
Ensembl chr 8:109,261,363...109,263,194

G

NADH:ubiquinone oxidoreductase subunit B5

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:115,519,248...115,533,589
Ensembl chr 2:115,519,154...115,533,589

G

NADH:ubiquinone oxidoreductase subunit S4

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846

G

NADH:ubiquinone oxidoreductase core subunit S7

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:9,452,556...9,460,135
Ensembl chr 7:9,450,392...9,460,195

G

nectin cell adhesion molecule 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360

G

neurofilament light chain

severity

protein:increased expression:plasma (human)
protein:increased expression:serum (human)
associated with central neurological symptoms;protein:increased expression:CSF (human)

RGD

PMID:32546655 PMID:33377539 PMID:33369818 PMID:33743046

RGD:127284882, RGD:127285022, RGD:127284893, RGD:127284892

NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793

G

NIMA-related kinase 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051

G

neogenin 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:59,273,860...59,426,486
Ensembl chr 8:59,275,569...59,430,348

G

neuroepithelial cell transforming 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr17:66,341,251...66,370,445
Ensembl chr17:66,340,728...66,370,441

G

neuropilin and tolloid like 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr19:21,344,299...21,415,524
Ensembl chr19:21,344,289...21,417,023

G

NFKB inhibitor alpha

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

niban apoptosis regulator 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:16,174,674...16,224,293
Ensembl chr 3:16,174,659...16,224,293

G

ninjurin 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704

G

NFKB inhibitor interacting Ras-like 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:85,554,704...85,562,072
Ensembl chr10:85,557,944...85,562,072

G

neurolysin

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:35,133,634...35,232,927
Ensembl chr 2:35,134,145...35,232,914

G

NME/NM23 nucleoside diphosphate kinase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408

G

NME/NM23 family member 7

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr13:76,657,303...76,786,768
Ensembl chr13:76,657,367...76,786,765

G

N-myc (and STAT) interactor

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 3:36,415,607...36,439,716
Ensembl chr 3:36,415,607...36,439,498

G

noggin

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339

G

nucleolar protein 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250

G

natriuretic peptide B

severity
disease_progression

associated with hyperglycemia;protein:increased expression:serum (human)
associated with diabetes mellitus

RGD

PMID:32434874 PMID:32406594 PMID:32427582 PMID:32345579 PMID:32293449 More...

RGD:30296677, RGD:32698682, RGD:30309200, RGD:30296681, RGD:30296680, RGD:30296679

NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168

G

neuronal regeneration related protein

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591

G

neuregulin 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884

G

nuclear receptor interacting protein 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761

G

neuropilin 1

protein:increased expression: pancreatic beta cell
protein:increased expression:olfactory epithelium

RGD

PMID:34081912 PMID:33082293

RGD:401901164, RGD:401901165

NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633

G

NS5A transactivated protein 4

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:175,494,406...175,507,281
Ensembl chr 2:175,494,304...175,510,663

G

5'-nucleotidase domain containing 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr16:6,322,485...6,330,538
Ensembl chr16:6,322,236...6,330,537

G

neurotrophic receptor tyrosine kinase 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770

G

neurotensin receptor 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:167,606,215...167,656,371
Ensembl chr 3:167,606,215...167,656,377

G

NUAK family kinase 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:19,330,034...19,401,918
Ensembl chr 7:19,329,933...19,401,913

G

nudix hydrolase 16

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:105,739,927...105,741,982
Ensembl chr 8:105,739,623...105,741,998

G

NUF2 component of NDC80 kinetochore complex

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766

G

2'-5' oligoadenylate synthetase 1A

CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: OAS1 polymorphism

PMID:16014697 PMID:25741868 PMID:28492532 PMID:35835913

NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517

G

OCRL, inositol polyphosphate-5-phosphatase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr X:127,089,508...127,140,362
Ensembl chr X:127,089,590...127,140,362

G

oleoyl-ACP hydrolase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr17:74,877,651...74,902,517
Ensembl chr17:74,877,655...74,902,518

G

olfactomedin-like 2A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:22,688,590...22,717,917
Ensembl chr 3:22,688,598...22,717,909

G

5-oxoprolinase (ATP-hydrolysing)

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:108,011,472...108,051,751
Ensembl chr 7:108,011,475...108,035,297

G

opsin 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:87,589,333...87,619,847
Ensembl chr13:87,589,333...87,619,847

G

optineurin

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251

G

origin recognition complex, subunit 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375

G

oncostatin M

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313

G

oncostatin M receptor

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 2:55,907,119...55,961,373
Ensembl chr 2:55,907,132...55,961,262

G

oligosaccharyltransferase complex non-catalytic subunit

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:219,250,549...219,266,076
Ensembl chr 2:219,236,952...219,266,107

G

otoferlin

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:25,928,018...26,024,631
Ensembl chr 6:25,928,055...26,024,631

G

purinergic receptor P2X 4

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr12:33,844,609...33,862,265
Ensembl chr12:33,844,396...33,862,253

G

purinergic receptor P2Y14

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 2:143,372,697...143,413,213
Ensembl chr 2:143,372,697...143,413,141

G

poly(A) binding protein, cytoplasmic 1

mRNA:decreased expression:antibody secreting B cells (human)

NCBI chr 7:67,777,438...67,789,731
Ensembl chr 7:67,777,381...67,789,744

G

peptidyl arginine deiminase 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:153,209,053...153,251,632
Ensembl chr 5:153,209,053...153,251,632

G

protein associated with LIN7 2, MAGUK p55 family member

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:79,173,488...79,257,542
Ensembl chr 4:79,124,806...79,254,140

G

3'-phosphoadenosine 5'-phosphosulfate synthase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:220,040,343...220,114,399
Ensembl chr 2:220,040,312...220,114,395

G

progestin and adipoQ receptor family member 4

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:12,758,970...12,762,649
Ensembl chr10:12,758,972...12,762,584

G

paired box 8

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363

G

PBX homeobox interacting protein 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:174,856,339...174,868,922
Ensembl chr 2:174,856,397...174,868,919

G

poly(rC) binding protein 1

mRNA:decreased expression:CD8+ T cells (human)

RGD

NCBI chr 4:118,972,698...118,974,705
Ensembl chr 4:118,972,661...118,976,500

G

polycomb group ring finger 5

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 1:234,063,854...234,180,022
Ensembl chr 1:234,063,892...234,175,315

G

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283

G

platelet derived growth factor subunit B

severity

protein:increased expression:plasma (human)

RGD

NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984

G

platelet derived growth factor C

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:166,316,870...166,493,449
Ensembl chr 2:166,316,803...166,493,433

G

platelet derived growth factor D

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395

G

protein disulfide isomerase family A, member 5

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr11:65,272,152...65,359,087
Ensembl chr11:65,272,155...65,359,084

G

decaprenyl diphosphate synthase subunit 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr17:85,059,953...85,098,739
Ensembl chr17:85,060,106...85,098,730

G

PDZ domain containing 4

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr X:151,530,390...151,560,779
Ensembl chr X:151,530,390...151,560,826

G

period circadian regulator 3

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607

G

phosphogluconate dehydrogenase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778

G

phosphoglucomutase 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr14:44,166,314...44,199,828
Ensembl chr14:44,164,425...44,199,967

G

phosphatase and actin regulator 1

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr17:21,560,364...22,040,166
Ensembl chr17:21,562,721...22,039,831

G

phosphatase and actin regulator 2

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 1:7,591,254...7,860,431
Ensembl chr 1:7,597,927...7,860,289

G

phosphatase and actin regulator 4

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 5:144,549,350...144,621,259
Ensembl chr 5:144,549,363...144,620,865

G

PH domain containing endocytic trafficking adaptor 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:113,855,437...113,861,910
Ensembl chr 7:113,857,249...113,861,871

G

pleckstrin homology-like domain, family A, member 2

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr 1:198,696,897...198,699,292
Ensembl chr 1:198,696,897...198,697,836

G

Pim-1 proto-oncogene, serine/threonine kinase

mRNA:decreased expression:CD4+ T cells (human)

NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174

G

pyruvate kinase M1/2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599

G

protein kinase, membrane associated tyrosine/threonine 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:12,748,221...12,758,995
Ensembl chr10:12,748,237...12,758,995

G

phospholipase A2, group XV

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr19:34,050,685...34,068,070
Ensembl chr19:34,050,694...34,068,063

G

phospholipase B domain containing 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:169,472,983...169,529,277
Ensembl chr 4:169,472,983...169,529,277

G

phospholipase D family, member 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:82,821,863...82,844,280
Ensembl chr 1:82,821,875...82,844,072

G

pleckstrin homology domain containing A1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:185,427,982...185,479,157
Ensembl chr 1:185,428,048...185,479,156

G

pleckstrin homology domain containing N1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:166,805,309...166,813,339
Ensembl chr 5:166,804,837...166,813,155

G

plasminogen

treatment

RGD

NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786

G

polo-like kinase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400

G

polo-like kinase 3

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317

G

proteolipid protein 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr X:14,834,249...14,837,648
Ensembl chr X:14,834,231...14,838,514

G

phospholipid scramblase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692

G

phorbol-12-myristate-13-acetate-induced protein 1

mRNA:increased expression:bronchoalveolar lavage (human)
mRNA:increased expression:CD14++ monocytes (human)

PMID:32377375 PMID:32407669

RGD:30296672 RGD:32716422

NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429

G

purine nucleoside phosphorylase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr15:24,170,607...24,178,269
Ensembl chr15:24,170,602...24,203,986

G

proline-rich nuclear receptor coactivator 1

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr 5:47,647,070...47,657,832
Ensembl chr 5:47,647,071...47,650,161

G

DNA polymerase theta

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr11:63,673,796...63,775,905
Ensembl chr11:63,673,816...63,775,878

G

proteasome maturation protein

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr12:7,162,098...7,174,737
Ensembl chr12:7,160,714...7,174,715

G

peroxisome proliferator-activated receptor gamma

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

PPARG coactivator 1 beta

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194

G

pro-platelet basic protein

mRNA:decreased expression:CD8+ T cells (human)

NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130

G

pancreatic progenitor cell differentiation and proliferation factor

mRNA:decreased expression:CD8+ T cells (human)

NCBI chr 3:168,299,309...168,301,040
Ensembl chr 3:168,299,791...168,301,036

G

peptidylprolyl isomerase F

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr16:1,257,197...1,263,919
Ensembl chr16:1,257,106...1,263,913

G

protein phosphatase 1, regulatory subunit 15B

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr13:44,577,840...44,585,737
Ensembl chr13:44,577,932...44,585,737

G

palmitoyl-protein thioesterase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:135,121,164...135,142,048
Ensembl chr 5:135,121,163...135,142,048

G

PR/SET domain 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488

G

PR/SET domain 8

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr14:11,403,202...11,424,059
Ensembl chr14:11,404,407...11,410,993

G

peroxiredoxin 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856

G

peroxiredoxin 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111

G

PRELI domain containing 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr17:9,305,349...9,308,389
Ensembl chr17:9,305,361...9,308,407

G

proline rich 11

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:71,898,858...71,943,325
Ensembl chr10:71,901,202...71,921,012

G

proline-rich transmembrane protein 4

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:57,766,054...57,777,087
Ensembl chr 4:57,766,263...57,777,020

G

serine protease 23

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:143,402,725...143,422,182
Ensembl chr 1:143,401,396...143,422,091

G

serine protease 57

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:9,915,667...9,922,996
Ensembl chr 7:9,917,484...9,922,922

G

presenilin 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174

G

proteasome 20S subunit beta 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:138,970,564...139,002,715
Ensembl chr 5:138,970,533...139,021,137

G

proteasome 20S subunit beta 7

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:22,357,777...22,417,748
Ensembl chr 3:22,354,698...22,417,937

G

proteasome 20S subunit beta 8

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr20:4,652,159...4,655,122
Ensembl chr20:4,652,159...4,655,283

G

patched 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333

G

prostaglandin D2 receptor

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr15:17,360,304...17,367,679
Ensembl chr15:17,360,304...17,367,679

G

prostaglandin D2 receptor 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:207,585,088...207,590,275
Ensembl chr 1:207,587,917...207,589,213

G

prostaglandin F2 receptor inhibitor

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:188,469,521...188,544,795
Ensembl chr 2:188,469,521...188,544,795

G

prostaglandin-endoperoxide synthase 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

protein tyrosine phosphatase, receptor type, O

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:170,164,071...170,374,790
Ensembl chr 4:170,164,431...170,374,771

G

protein tyrosine phosphatase, receptor type, S

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:1,245,408...1,307,015
Ensembl chr 9:1,245,410...1,306,947

G

pyrroline-5-carboxylate reductase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549

G

RAB11 family interacting protein 5

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:117,871,301...117,908,819
Ensembl chr 4:117,871,308...117,908,741

G

RAB13, member RAS oncogene family

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:175,674,894...175,680,043
Ensembl chr 2:175,675,005...175,680,036

G

RAB20, member RAS oncogene family

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr16:78,019,337...78,043,529
Ensembl chr16:78,019,337...78,043,529

G

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:61,907,476...61,990,170
Ensembl chr 9:61,907,758...61,961,209

G

RasGEF domain family, member 1B

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr14:9,859,512...10,380,044
Ensembl chr14:9,860,247...10,379,741

G

RB binding protein 8, endonuclease

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846

G

reeler domain containing 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr19:29,141,898...29,159,970

G

renin binding protein

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr X:151,661,463...151,670,538
Ensembl chr X:151,661,458...151,670,516

G

resistin

protein:increased expression:plasma (human)

RGD

NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620

G

regulator of G-protein signaling 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr13:56,018,546...56,022,889
Ensembl chr13:56,018,554...56,022,984

G

regulator of G-protein signaling 16

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857

G

RHEB like 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:130,026,255...130,031,127
Ensembl chr 7:130,026,341...130,030,248

G

ras homolog family member B

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108

G

Rho-related BTB domain containing 3

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:5,363,388...5,419,164
Ensembl chr 2:5,363,388...5,419,041

G

RecQ mediated genome instability 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr17:6,256,533...6,264,523
Ensembl chr17:6,256,450...6,264,695

G

5.8S ribosomal RNA

mRNA:decreased expression:peripheral blood mononuclear cell (human)

G

RNA component of signal recognition particle 7SL1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:87,636,808...87,637,106
Ensembl chr 6:87,636,804...87,637,103

G

ribonuclease A family member 1, pancreatic

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr15:24,361,924...24,363,633
Ensembl chr15:24,361,927...24,363,624

G

ribonuclease A family member 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr15:24,449,618...24,450,427
Ensembl chr15:24,449,611...24,450,479

G

ribonuclease A family member 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr15:24,511,894...24,512,764
Ensembl chr15:24,511,891...24,512,790

G

ring finger protein 138

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr18:12,291,557...12,315,931
Ensembl chr18:12,291,590...12,315,930

G

ring finger protein 19B

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 5:141,406,085...141,431,376
Ensembl chr 5:141,406,118...141,431,380

G

rogdi atypical leucine zipper

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:10,567,834...10,572,453
Ensembl chr10:10,567,834...10,572,452

G

rabphilin 3A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr12:35,542,389...35,618,901
Ensembl chr12:35,542,728...35,617,592

G

ribosomal protein L26 like 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:16,520,383...16,524,604

G

ribosomal protein S6 kinase A5

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224

G

RAS related

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:95,500,582...95,504,362
Ensembl chr 1:95,500,566...95,504,357

G

ribonucleotide reductase regulatory subunit M2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773

G

radical S-adenosyl methionine domain containing 2

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699

G

round spermatid basic protein 1-like

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 4:14,138,076...14,203,972
Ensembl chr 4:14,139,031...14,201,147

G

RT1 class II, locus Bb

mRNA:decreased expression:memory B cells (human)

NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597

G

RT1 class I, locus CE16

mRNA:decreased expression:antibody secreting B cells (human)

NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563

G

RT1 class II, locus Db1

mRNA:decreased expression:memory B cells (human)

NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258

G

RUNX family transcription factor 3

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:147,360,587...147,419,161
Ensembl chr 5:147,360,994...147,419,156

G

S100 calcium binding protein A11

mRNA:decreased expression:CD4+ T cells (human)

NCBI chr 2:179,191,688...179,197,098
Ensembl chr 2:179,191,715...179,197,044

G

sphingosine-1-phosphate receptor 1

mRNA:decreased expression:CD8+ T cells (human)

NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681

G

sphingosine-1-phosphate receptor 5

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:19,786,676...19,791,862
Ensembl chr 8:19,786,663...19,791,795

G

SAM domain, SH3 domain and nuclear localization signals, 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr11:14,484,523...14,534,900
Ensembl chr11:14,483,893...14,534,900

G

Sin3A associated protein 30

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr16:32,747,777...32,753,114
Ensembl chr16:32,747,734...32,753,112

G

suppressor APC domain containing 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:8,186,089...8,195,119
Ensembl chr 3:8,187,266...8,192,546

G

spermidine/spermine N1-acetyl transferase 1

mRNA:increased expression:bronchoalveolar lavage (human)
mRNA:increased expression:CD14++ monocytes (human)

PMID:32377375 PMID:32407669

RGD:30296672 RGD:32716422

NCBI chr X:40,158,354...40,161,641
Ensembl chr X:40,157,046...40,196,813

G

scavenger receptor class B, member 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr14:15,558,271...15,609,813
Ensembl chr14:15,558,236...15,609,813

G

small Cajal body-specific RNA 21

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr10:54,070,959...54,071,098
Ensembl chr10:54,070,959...54,071,098

G

stearoyl-CoA desaturase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562

G

SLP adaptor and CSK interacting membrane protein

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171

G

serine carboxypeptidase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:73,703,275...73,732,892
Ensembl chr10:73,703,278...73,732,850

G

syndecan 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:31,562,799...31,585,267
Ensembl chr 6:31,562,739...31,585,264

G

syndecan 4

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580

G

succinate dehydrogenase complex subunit D

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:50,944,702...50,954,298
Ensembl chr 8:50,944,704...50,954,238

G

SEC11 homolog A, signal peptidase complex subunit

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:134,881,448...134,909,427
Ensembl chr 1:134,875,265...134,915,069

G

Sec23 homolog B, COPII coat complex component

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:131,939,011...131,981,489
Ensembl chr 3:131,939,337...131,981,489

G

selectin E

severity

mRNA,protein:increased expression:plasma (human)
CTD Direct Evidence: marker/mechanism

CTD
RGD

PMID:35255492 PMID:32458111

NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741

G

selectin L

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456

G

selectin P ligand

mRNA:decreased expression:CD4+ T cells (human)

NCBI chr12:42,796,690...42,809,908
Ensembl chr12:42,796,580...42,812,585

G

semaphorin 4C

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:38,791,668...38,802,171
Ensembl chr 9:38,791,670...38,802,128

G

semaphorin 6B

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:950,939...967,905
Ensembl chr 9:950,939...961,521

G

septin 10

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr20:27,101,764...27,194,997
Ensembl chr20:27,101,752...27,194,780

G

serpin family A member 1

ClinVar Annotator: match by term: Susceptibility to severe coronavirus disease (COVID-19)

PMID:301355 PMID:1082356 PMID:1608473 PMID:1889260 PMID:2339709 More...

NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339

G

serpin family B member 10

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:23,553,348...23,571,182
Ensembl chr13:23,553,430...23,571,182

G

serpin family F member 2

severity

DNA:SNP: :

RGD

NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243

G

serpin family G member 1

severity

DNA:SNP: :

RGD

NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034

G

sarcoglycan, delta

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr10:31,346,480...32,328,364
Ensembl chr10:31,280,511...31,724,840

G

serum/glucocorticoid regulated kinase 1

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283

G

SH2 domain containing 2A

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:173,312,253...173,318,810
Ensembl chr 2:173,312,253...173,318,810

G

SH2 domain containing 4A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr16:21,339,010...21,409,360
Ensembl chr16:21,340,015...21,409,260

G

SH3 and PX domains 2B

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:16,918,611...17,027,499
Ensembl chr10:16,918,679...17,005,170

G

SHC binding and spindle associated 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr16:84,672,277...84,703,843
Ensembl chr16:84,672,321...84,703,844

G

serine hydroxymethyltransferase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:45,468,698...45,490,833
Ensembl chr10:45,468,700...45,497,820

G

shroom family member 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:37,621,149...37,631,895
Ensembl chr10:37,621,723...37,631,256

G

single Ig and TIR domain containing

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:196,195,363...196,208,692
Ensembl chr 1:196,199,462...196,202,269

G

SIL1 nucleotide exchange factor

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr18:26,872,423...27,104,365
Ensembl chr18:26,872,429...27,104,332

G

spindle and kinetochore associated complex subunit 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr18:67,794,722...67,805,037
Ensembl chr18:67,794,725...67,805,037

G

SLAM family member 7

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr13:84,135,656...84,154,528
Ensembl chr13:84,136,899...84,154,105

G

solute carrier family 16 member 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611

G

solute carrier family 16 member 8

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:110,818,274...110,822,069
Ensembl chr 7:110,818,274...110,822,069

G

solute carrier family 1 member 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605

G

solute carrier family 1 member 5

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952

G

solute carrier family 1 member 7

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:122,731,003...122,775,139
Ensembl chr 5:122,731,003...122,775,134

G

solute carrier family 22 member 16

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr20:43,972,808...44,068,447
Ensembl chr20:43,972,836...44,065,019

G

solute carrier family 25 member 29

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:127,742,027...127,752,915
Ensembl chr 6:127,742,033...127,752,940

G

solute carrier family 30 member 4

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:109,753,270...109,775,306
Ensembl chr 3:109,753,273...109,775,306

G

solute carrier family 35, member A5

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr11:55,653,376...55,674,476
Ensembl chr11:55,653,394...55,674,473

G

solute carrier family 38, member 7

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr19:9,209,203...9,225,472
Ensembl chr19:9,209,257...9,225,454

G

solute carrier family 39, member 11

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:98,275,958...98,697,042
Ensembl chr10:98,275,960...98,611,295

G

solute carrier family 43, member 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:70,008,160...70,030,324
Ensembl chr 3:70,009,313...70,029,749

G

solute carrier family 45, member 3

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr13:43,407,293...43,427,588
Ensembl chr13:43,407,293...43,427,588

G

solute carrier family 4 member 4

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883

G

solute carrier organic anion transporter family, member 4a1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:167,559,177...167,578,307
Ensembl chr 3:167,559,316...167,578,305

G

schlafen family member 9

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:67,909,105...67,955,912
Ensembl chr10:67,909,106...67,925,383

G

SLIT and NTRK-like family, member 4

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr X:142,706,495...142,718,968
Ensembl chr X:142,706,338...142,718,575

G

SMAD family member 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:10,548,693...10,580,334
Ensembl chr 4:10,548,751...10,580,326

G

structural maintenance of chromosomes flexible hinge domain containing 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 9:111,243,445...111,387,272
Ensembl chr 9:111,247,702...111,349,665

G

smoothelin

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr14:78,398,595...78,420,908
Ensembl chr14:78,397,778...78,420,886

G

SNAP-associated protein

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:175,971,575...175,974,164
Ensembl chr 2:175,971,257...175,974,231

G

small nucleolar RNA, H/ACA box 73b

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:144,545,179...144,545,382
Ensembl chr 5:144,545,179...144,545,382

G

small nucleolar RNA, H/ACA box 73B like 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:119,852,783...119,852,985
Ensembl chr 8:119,852,783...119,852,985

G

small nucleolar RNA, H/ACA box 75

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:87,000,248...87,000,384
Ensembl chr 9:87,000,248...87,000,384

G

sorting nexin 10

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 4:80,612,648...80,677,005
Ensembl chr 4:80,612,669...80,676,996

G

sorting nexin 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr20:45,992,446...46,025,361
Ensembl chr20:45,992,720...46,025,379

G

sorting nexin 32

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:202,801,090...202,818,731
Ensembl chr 1:202,802,394...202,818,743

G

sorting nexin 8

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr12:14,251,829...14,300,435
Ensembl chr12:14,251,859...14,300,432

G

sortilin 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354

G

sosondowah ankyrin repeat domain family member D

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr X:116,292,030...116,293,660
Ensembl chr X:116,292,030...116,293,660

G

SRY-box transcription factor 13

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr13:44,831,097...44,875,522
Ensembl chr13:44,831,085...44,875,762

G

sperm associated antigen 5

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,198,768...63,216,745

G

spermatogenesis associated, serine-rich 2-like

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:59,319,949...59,493,864
Ensembl chr 9:59,320,276...59,493,967

G

spondin 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226

G

sepiapterin reductase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:117,671,948...117,676,292
Ensembl chr 4:117,671,949...117,675,678

G

sprouty RTK signaling antagonist 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr15:82,692,291...82,697,408
Ensembl chr15:82,692,143...82,698,009

G

serine palmitoyltransferase, long chain base subunit 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:106,948,682...107,031,532
Ensembl chr 6:106,950,949...107,031,542

G

sulfide quinone oxidoreductase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:109,841,225...109,886,724
Ensembl chr 3:109,841,250...109,960,778

G

steroid 5 alpha-reductase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461

G

SLIT-ROBO Rho GTPase activating protein 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:57,329,532...57,594,681
Ensembl chr 7:57,329,532...57,596,196

G

small RNA binding exonuclease protection factor La

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 3:54,616,616...54,626,203
Ensembl chr 3:54,616,619...54,626,203

G

ST14 transmembrane serine protease matriptase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517

G

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr17:76,740,755...76,884,178
Ensembl chr17:76,745,224...76,884,299

G

SH3 and cysteine rich domain 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:63,343,078...63,350,590
Ensembl chr 7:63,343,186...63,350,589

G

StAR-related lipid transfer domain containing 13

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr12:566,282...959,372
Ensembl chr12:566,310...959,421

G

signal transducer and activator of transcription 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

G

STEAP3 metalloreductase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr13:31,351,954...31,397,344
Ensembl chr13:31,351,954...31,396,519

G

STIL, centriolar assembly protein

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730

G

steroid sulfatase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr X:42,225,131...42,233,403
Ensembl chr X:42,225,372...42,233,402

G

STT3 oligosaccharyltransferase complex catalytic subunit A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:36,443,623...36,483,111
Ensembl chr 8:36,446,788...36,483,293

G

sulfotransferase family 1A member 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562

G

synapsin II

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192

G

synaptotagmin-like 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:144,272,870...144,379,310
Ensembl chr 1:144,273,360...144,379,222

G

T-cell activation RhoGTPase activating protein

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr 1:47,170,725...47,179,705
Ensembl chr 1:47,170,725...47,179,792

G

TRAF family member-associated NFKB activator

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 3:46,114,230...46,190,270
Ensembl chr 3:46,114,274...46,190,264

G

TBC1 domain family, member 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:60,884,114...60,931,717
Ensembl chr 5:60,884,124...60,931,352

G

transducin (beta)-like 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr12:21,517,600...21,531,896
Ensembl chr12:21,520,682...21,531,896

G

Tcl1 family Akt coactivator A

mRNA:decreased expression:memory B cells (human)

NCBI chr 6:124,125,032...124,131,025
Ensembl chr 6:124,125,032...124,131,025

G

transcobalamin 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr14:78,813,343...78,828,549
Ensembl chr14:78,813,343...78,828,489

G

tudor domain containing 9

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:131,029,644...131,145,076
Ensembl chr 6:131,029,652...131,144,651

G

testis expressed 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:91,436,629...91,546,240
Ensembl chr10:91,436,694...91,546,270

G

transcription factor Dp-2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:96,760,459...96,901,466
Ensembl chr 8:96,760,504...96,896,682

G

transforming growth factor beta receptor 3

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341

G

thrombospondin 1

protein:increased expression:plasma (human)

RGD

NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440

G

TOPBP1-interacting checkpoint and replication regulator

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:133,597,618...133,639,513
Ensembl chr 1:133,597,716...133,639,523

G

translocase of inner mitochondrial membrane 8 homolog B

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:50,954,350...50,955,730
Ensembl chr 8:50,954,342...50,955,729

G

TIMP metallopeptidase inhibitor 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664

G

TIMP metallopeptidase inhibitor 4

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:148,306,021...148,312,558
Ensembl chr 4:148,304,490...148,312,558

G

tight junction protein 3

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:8,427,650...8,446,279
Ensembl chr 7:8,432,811...8,446,279

G

thymidine kinase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920

G

thymidine kinase 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr19:708,859...731,786
Ensembl chr19:708,891...730,924

G

toll-like receptor 4

ClinVar Annotator: match by term: Susceptibility to severe coronavirus disease (COVID-19)

PMID:10835634 PMID:12124407 PMID:15547160 PMID:15829498 PMID:16879199 More...

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

G

toll-like receptor 7

severity

DNA:SNPs:Cds:

RGD

NCBI chr X:27,027,380...27,054,309
Ensembl chr X:27,027,425...27,054,754

G

transmembrane protein 106A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:86,506,908...86,515,915
Ensembl chr10:86,506,936...86,515,892

G

transmembrane protein 106B

CTD Direct Evidence: marker/mechanism

NCBI chr 4:41,328,125...41,347,315
Ensembl chr 4:41,327,994...41,345,619

G

transmembrane protein 107

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr10:53,772,153...53,774,685
Ensembl chr10:53,771,784...53,774,676

G

transmembrane protein 121B

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:153,695,191...153,700,104
Ensembl chr 4:153,698,194...153,699,912

G

transmembrane protein 123

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 8:4,922,077...4,952,228
Ensembl chr 8:4,922,098...4,952,224

G

transmembrane protein 150B

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:69,124,943...69,134,617
Ensembl chr 1:69,125,710...69,141,034

G

transmembrane protein 182

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:43,059,432...43,111,318
Ensembl chr 9:43,059,439...43,111,317

G

transmembrane protein 38a

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr16:17,258,160...17,274,204
Ensembl chr16:17,258,164...17,273,415

G

transmembrane protein 45A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr11:43,713,309...43,799,526
Ensembl chr11:43,713,782...43,799,526

G

transmembrane protein 60

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 4:14,210,029...14,214,884
Ensembl chr 4:14,210,029...14,215,063

G

transmembrane and immunoglobulin domain containing 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:193,338,950...193,415,107
Ensembl chr 2:193,338,950...193,415,105

G

transmembrane serine protease 4

CTD Direct Evidence: marker/mechanism

NCBI chr 8:45,475,819...45,508,409
Ensembl chr 8:45,476,053...45,508,409

G

thiol methyltransferase 1A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:131,452,099...131,460,154
Ensembl chr 7:131,451,641...131,460,154

G

transmembrane O-mannosyltransferase targeting cadherins 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:181,142,937...181,357,979
Ensembl chr 4:181,146,251...181,359,289

G

transmembrane O-mannosyltransferase targeting cadherins 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:40,392,377...40,806,685
Ensembl chr 7:40,394,220...40,807,298

G

thioredoxin-related transmembrane protein 1

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr 6:88,960,691...88,971,744
Ensembl chr 6:88,960,695...88,971,301

G

tumor necrosis factor

disease_progression
severity

associated with diabetes mellitus
ClinVar Annotator: match by term: Susceptibility to severe coronavirus disease (COVID-19)
CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma (human)
protein:increased expression:serum (human)

ClinVar
CTD
RGD

PMID:8056188 PMID:9818939 PMID:10450718 PMID:11261930 PMID:11506397 More...

RGD:30296681, RGD:38501088, RGD:30310229, RGD:30309212, RGD:30309200

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF alpha induced protein 3

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282

G

TNF alpha induced protein 8 like 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:182,710,433...182,726,724
Ensembl chr 2:182,709,378...182,726,760

G

TNF receptor superfamily member 13C

mRNA:decreased expression:bronchoalveolar lavage (human)

NCBI chr 7:113,736,046...113,738,523
Ensembl chr 7:113,736,055...113,738,517

G

TNF receptor superfamily member 17

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:4,301,023...4,306,889
Ensembl chr10:4,301,038...4,306,788

G

TNF receptor superfamily member 1A

ClinVar Annotator: match by term: Susceptibility to severe coronavirus disease (COVID-19)

PMID:22801493 PMID:24033266 PMID:25741868 PMID:28492532

NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591

G

tumor necrosis factor receptor superfamily, member 22

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:198,840,452...198,860,713
Ensembl chr 1:198,840,453...198,856,309

G

TNF superfamily member 10

mRNA:increased expression:bronchoalveolar lavage (human)
mRNA:increased expression:peripheral blood mononuclear cell (human)

PMID:32228226 PMID:32407669

RGD:28912744 RGD:30296672

NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135

G

TNF superfamily member 12

mRNA:decreased expression:bronchoalveolar lavage (human)

NCBI chr10:54,403,870...54,413,213
Ensembl chr10:54,403,870...54,413,213

G

TNF superfamily member 13b

mRNA:increased expression:bronchoalveolar lavage (human)

NCBI chr16:79,462,406...79,492,888
Ensembl chr16:79,462,402...79,492,693

G

troponin T2, cardiac type

severity

protein:increased expression:serum (human)

RGD

NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388

G

trinucleotide repeat containing adaptor 6C

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr10:102,908,958...102,979,543
Ensembl chr10:102,868,828...102,978,194

G

DNA topoisomerase II alpha

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874

G

TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:55,388,033...55,399,937
Ensembl chr 5:55,387,632...55,399,937

G

tumor protein p53 inducible protein 3

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 6:27,818,327...27,825,753

G

triosephosphate isomerase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541

G

tropomyosin 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:57,770,919...57,780,278
Ensembl chr 5:57,770,864...57,779,992

G

tubulin polymerization promoting protein

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:29,257,111...29,281,134
Ensembl chr 1:29,261,255...29,281,134

G

tyrosylprotein sulfotransferase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr12:26,544,536...26,605,706
Ensembl chr12:26,544,536...26,605,704

G

TPX2, microtubule nucleation factor

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468

G

transformer 2 beta

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr11:78,788,880...78,807,252
Ensembl chr11:78,788,884...78,807,249

G

tripartite motif-containing 7

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:33,205,491...33,221,482
Ensembl chr10:33,205,491...33,221,468

G

tripartite motif containing 71

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:114,193,439...114,250,807
Ensembl chr 8:114,199,187...114,250,807

G

thyroid hormone receptor interactor 13

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:29,357,093...29,402,078
Ensembl chr 1:29,357,130...29,402,074

G

trophinin associated protein

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:130,233,534...130,242,369
Ensembl chr 7:130,234,544...130,242,365

G

transient receptor potential cation channel, subfamily M, member 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181

G

TSC22 domain family, member 3

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr X:104,217,898...104,277,886
Ensembl chr X:104,217,925...104,276,861

G

teashirt zinc finger homeobox 2

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:158,405,469...158,666,915
Ensembl chr 3:158,405,423...158,850,128

G

translocator protein

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450

G

TSPO associated protein 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr10:72,554,220...72,586,402
Ensembl chr10:72,560,980...72,586,412

G

TSPY-like 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr20:38,082,003...38,084,562
Ensembl chr20:38,081,951...38,084,554
Ensembl chr20:38,081,951...38,084,554

G

Ttk protein kinase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651

G

tubulin, gamma 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:86,052,845...86,059,436
Ensembl chr10:86,052,743...86,059,433

G

twinfilin actin-binding protein 2

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:106,845,253...106,858,298
Ensembl chr 8:106,845,253...106,858,298

G

thioredoxin domain containing 5

mRNA:decreased expression:antibody secreting B cells (human)

NCBI chr17:26,289,880...26,318,025
Ensembl chr17:26,289,880...26,318,025

G

thioredoxin interacting protein

mRNA:decreased expression:CD4+ T cells (human)

NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886

G

tyrosine kinase 2

CTD Direct Evidence: marker/mechanism

NCBI chr 8:19,641,881...19,667,157
Ensembl chr 8:19,641,884...19,667,044

G

thymidylate synthetase

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536

G

uveal autoantigen with coiled-coil domains and ankyrin repeats

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 8:61,259,415...61,347,789
Ensembl chr 8:61,259,477...61,347,789

G

UDP-N-acetylglucosamine pyrophosphorylase 1 like 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:8,172,335...8,180,505
Ensembl chr 3:8,173,216...8,180,443

G

ubiquitin C

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925

G

ubiquitin-conjugating enzyme E2C

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339

G

ubiquitin-conjugating enzyme E2, J1

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr 5:47,422,476...47,441,476
Ensembl chr 5:47,422,587...47,441,461

G

uncoupling protein 2

mRNA:decreased expression:CD4+ T cells (human)

NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611

G

UDP-glucose ceramide glucosyltransferase

CTD Direct Evidence: marker/mechanism

NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393

G

unc-13 homolog B

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 5:57,288,999...57,504,110
Ensembl chr 5:57,289,227...57,502,926

G

uroplakin 3B

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr12:20,630,231...20,637,634
Ensembl chr12:20,631,525...20,637,724

G

voltage-dependent anion channel 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640

G

vascular endothelial growth factor A

severity

protein:increased expression:plasma (human)

RGD

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

G

vimentin

mRNA:decreased expression:antibody secreting B cells (human)

NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187

G

vacuolar protein sorting 25 homolog

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr10:86,196,062...86,201,606
Ensembl chr10:86,188,812...86,231,829

G

V-set and immunoglobulin domain containing 10 like

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:93,871,487...93,880,157
Ensembl chr 1:93,851,774...93,879,566

G

V-set and immunoglobulin domain containing 4

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr X:61,144,926...61,170,212
Ensembl chr X:61,144,928...61,170,212

G

WASP family member 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr20:44,325,815...44,372,999
Ensembl chr20:44,325,795...44,372,996

G

WD repeat domain 74

mRNA:increased expression:CD14++ monocytes (human)

NCBI chr 1:205,631,769...205,636,558
Ensembl chr 1:205,631,824...205,636,563

G

WAP four-disulfide core domain 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr19:47,720,191...47,739,121
Ensembl chr19:47,720,423...47,739,108

G

xyloside xylosyltransferase 1

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr11:69,658,481...69,790,938
Ensembl chr11:69,658,460...69,790,730

G

YES proto-oncogene 1, Src family tyrosine kinase

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 9:113,200,256...113,275,942
Ensembl chr 9:113,200,256...113,299,837

G

yippee-like 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr11:83,921,799...83,936,409

G

yippee-like 4

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:69,815,373...69,820,708
Ensembl chr 3:69,816,175...69,820,707

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827

G

zinc finger and BTB domain containing 20

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr11:57,052,129...57,791,214
Ensembl chr11:57,072,880...57,510,210

G

zinc finger and BTB domain containing 32

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:85,841,931...85,851,116
Ensembl chr 1:85,841,931...85,844,236

G

zinc finger and BTB domain containing 43

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:16,744,535...16,763,854
Ensembl chr 3:16,744,535...16,763,909

G

zinc finger protein 36

mRNA:increased expression:bronchoalveolar lavage (human)
mRNA:increased expression:CD14++ monocytes (human)

PMID:32377375 PMID:32407669

RGD:30296672 RGD:32716422

NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564

G

zinc finger protein 365

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr20:20,666,240...20,689,734
Ensembl chr20:20,666,240...20,691,238

G

zinc finger protein 366

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 2:30,578,552...30,640,546
Ensembl chr 2:30,578,715...30,642,182

G

zinc finger protein 36, C3H type-like 1

mRNA:decreased expression:memory B cells (human)

NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748

G

zinc finger protein 36, C3H type-like 2

mRNA:decreased expression:memory B cells (human)

NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064

G

zinc finger protein 574

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:80,667,984...80,678,257
Ensembl chr 1:80,664,259...80,679,427

G

zinc finger protein 683

mRNA:decreased expression:CD8+ T cells (human)

NCBI chr 5:146,277,972...146,285,856
Ensembl chr 5:146,278,978...146,285,000

G

zinc finger protein 830

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr10:67,701,340...67,702,804
Ensembl chr10:67,701,073...67,704,523

G

zinc finger protein 831

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr 3:163,393,787...163,510,654
Ensembl chr 3:163,438,006...163,509,095

G

zinc finger protein, multitype 1

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591

G

zinc finger FYVE-type containing 28

mRNA:decreased expression:peripheral blood mononuclear cell (human)

NCBI chr14:76,468,424...76,554,039
Ensembl chr14:76,468,424...76,554,039

G

Zn regulated GTPase metalloprotein activator 1A

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr 1:222,568,278...222,612,937
Ensembl chr 1:222,564,545...222,610,629

G

ZW10 interacting kinetochore protein

mRNA:increased expression:peripheral blood mononuclear cell (human)

NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957

long COVID

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

NLR family, pyrin domain containing 3

ClinVar Annotator: match by term: Long COVID-19

NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811

Middle East respiratory syndrome

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

arginase 1

mRNA:increased expression:lung

RGD

NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422

G

complement C5a receptor 1

treatment

RGD

NCBI chr 1:76,948,622...76,959,826

G

C-C motif chemokine ligand 2

RGD

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 3

RGD

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

G

CD14 molecule

mRNA:increased expression:lung

RGD

NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261

G

CD40 ligand

treatment

RGD

NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306

G

C-X-C motif chemokine ligand 10

RGD

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

G

C-X-C motif chemokine ligand 9

RGD

NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435

G

dipeptidylpeptidase 4

treatment
severity

human gene in mouse model

PMID:30256968 PMID:31838832 PMID:30626685

RGD:30309959, RGD:30309204, RGD:30309198

NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901

G

interferon, alpha 4

disease_progression

RGD

NCBI chr 5:103,069,174...103,070,120
Ensembl chr 5:103,069,483...103,070,052

G

interferon beta 1

disease_progression

RGD

NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523

G

interferon gamma

treatment

RGD

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

interleukin 10

mRNA:increased expression:lung (mouse)

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 1 alpha

onset

mRNA:increased expression:lung (mouse)

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 1 beta

onset
treatment

mRNA:increased expression:lung (mouse)

PMID:32364527 PMID:30634407 PMID:30626685

RGD:27226699, RGD:30309958, RGD:30309198

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 23 subunit alpha

mRNA:decreased expression:lung (mouse)

NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923

G

interleukin 6

protein:increased expression:serum:

RGD

PMID:30626685 PMID:30634407

RGD:30309198, RGD:30309958

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

interleukin 7

onset

mRNA:altered expression:lung (mouse)

NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075

G

tumor necrosis factor

protein:increased expression:serum:

RGD

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

multisystem inflammatory syndrome in children

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

CD163 molecule

ClinVar Annotator: match by term: Multisystem inflammatory syndrome in children

NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878

G

CD84 molecule

ClinVar Annotator: match by term: Multisystem inflammatory syndrome in children

NCBI chr13:84,327,580...84,367,153
Ensembl chr13:84,327,553...84,362,076

G

interferon-induced protein 44

ClinVar Annotator: match by term: Multisystem inflammatory syndrome in children

NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844

G

interferon-induced protein 44-like

ClinVar Annotator: match by term: Multisystem inflammatory syndrome in children

NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359

G

interferon induced with helicase C domain 1

ClinVar Annotator: match by term: Multisystem inflammatory syndrome in children

PMID:25741868 PMID:28492532 PMID:34185153

NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456

G

interferon, alpha 4

ClinVar Annotator: match by term: Multisystem inflammatory syndrome in children

NCBI chr 5:103,069,174...103,070,120
Ensembl chr 5:103,069,483...103,070,052

G

interferon alpha and beta receptor subunit 2

ClinVar Annotator: match by term: Multisystem inflammatory syndrome in children

NCBI chr11:30,613,576...30,645,958
Ensembl chr11:30,613,767...30,668,124

G

interferon beta 1

ClinVar Annotator: match by term: Multisystem inflammatory syndrome in children

NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523

G

interleukin 22 receptor subunit alpha 2

ClinVar Annotator: match by term: Multisystem inflammatory syndrome in children

NCBI chr 1:14,353,736...14,377,844
Ensembl chr 1:14,364,489...14,377,844

G

interleukin-1 receptor-associated kinase 3

ClinVar Annotator: match by term: Multisystem inflammatory syndrome in children

NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121

G

interferon regulatory factor 3

ClinVar Annotator: match by term: Multisystem inflammatory syndrome in children

NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935

G

lymphocyte antigen 9

ClinVar Annotator: match by term: Multisystem inflammatory syndrome in children

NCBI chr13:84,079,345...84,100,783
Ensembl chr13:84,079,458...84,100,823

G

NLR family, pyrin domain containing 12

ClinVar Annotator: match by term: Multisystem inflammatory syndrome in children

PMID:25741868 PMID:28492532

NCBI chr 1:65,932,610...65,969,873
Ensembl chr 1:65,932,595...65,960,934

G

NLR family pyrin domain containing 2

ClinVar Annotator: match by term: Multisystem inflammatory syndrome in children

NCBI chr 1:69,515,505...69,554,689
Ensembl chr 1:69,515,505...69,554,454

G

RAB27A, member RAS oncogene family

ClinVar Annotator: match by term: Multisystem inflammatory syndrome in children

PMID:10835631 PMID:15163896 PMID:23160464 PMID:25741868 PMID:28492532

NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829

G

toll-like receptor 3

ClinVar Annotator: match by term: Multisystem inflammatory syndrome in children

PMID:26513235 PMID:28368532 PMID:28492532

NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545

G

toll-like receptor 6

ClinVar Annotator: match by term: Multisystem inflammatory syndrome in children

NCBI chr14:43,362,164...43,374,500
Ensembl chr14:43,362,164...43,375,685

G

Tnf receptor-associated factor 3

ClinVar Annotator: match by term: Multisystem inflammatory syndrome in children

NCBI chr 6:130,199,696...130,307,168
Ensembl chr 6:130,206,484...130,305,481

G

tripartite motif-containing 69

ClinVar Annotator: match by term: Multisystem inflammatory syndrome in children

NCBI chr 3:109,111,468...109,135,255
Ensembl chr 3:109,111,468...109,132,037

severe acute respiratory syndrome

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase

susceptibility

RGD

NCBI chr 3:10,162,087...10,182,835
Ensembl chr 3:10,162,096...10,191,423

G

angiotensin I converting enzyme

CTD Direct Evidence: marker/mechanism

NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131

G

angiotensin converting enzyme 2

treatment
susceptibility
severity

CTD Direct Evidence: marker/mechanism
mRNA, protein:decreased expression:heart (mouse)
human gene in a mouse model

CTD
RGD

PMID:14647384 PMID:16007097 PMID:16166518 PMID:16339146 PMID:19453650 More...

RGD:40818405, RGD:32716426, RGD:30309965, RGD:30309202

NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977

G

alanyl aminopeptidase, membrane

disease_progression

mRNA:increased expression:lung (human)

RGD

NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789

G

bactericidal/permeability-increasing protein

disease_progression

mRNA:increased expression:lung (human)

RGD

NCBI chr 3:146,909,626...146,936,487
Ensembl chr 3:146,909,629...146,936,221

G

complement C1q B chain

disease_progression

mRNA:increased expression:lung (human)

NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407

G

complement C5a receptor 1

disease_progression

mRNA:increased expression:lung (human)

NCBI chr 1:76,948,622...76,959,826

G

caspase 3

disease_progression

mRNA:increased expression:lung (human)

RGD

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 9

disease_progression

mRNA:increased expression:lung (human)

RGD

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

C-C motif chemokine ligand 1

mRNA: increased expression:lung (mouse)

RGD

NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159

G

C-C motif chemokine ligand 2

treatment
severity

CTD Direct Evidence: marker/mechanism
protein:increased expression:bronchoalveolar lavage (human)
protein:increased expression:serum (human)
mRNA, protein: increased expression, altered expression:lung (mouse)
protein:increased expression:plasma (human)

CTD
RGD

PMID:20484496 PMID:15888207 PMID:32553273 PMID:15602737 PMID:15356152 More...

RGD:34201108, RGD:32716426, RGD:32716399, RGD:30309221, RGD:30309220, RGD:30309219, RGD:30309218

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 3

mRNA, protein: increased expression, altered expression:lung (mouse)

RGD

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

G

C-C motif chemokine ligand 5

severity
treatment

Severe Acute Respiratory Syndrome; DNA:transversion:5' utr:-28C>G (human)
protein:increased expression:bronchoalveolar lavage (human)
mRNA, protein: increased expression, altered expression:lung, brain (mouse)
protein:increased expression:plasma (human)
mRNA:increased expression:lung (mouse)

RGD

PMID:19258635 PMID:15888207 PMID:15865221 PMID:32553273 PMID:15356152 More...

RGD:4891448, RGD:34201108, RGD:33769580, RGD:32716426, RGD:30309221, RGD:30309220, RGD:30309218, RGD:30309207

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

C-C motif chemokine receptor 1

mRNA:increased expression:lung (mouse)

RGD

NCBI chr 8:123,556,286...123,561,841

G

C-C motif chemokine receptor 3

mRNA:altered expression:lung (mouse)

RGD

NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990

G

CD14 molecule

disease_progression

mRNA:increased expression:lung (human)

NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261

G

CD3 epsilon subunit of T-cell receptor complex

protein:increased expression:Tcell, testis (human)

RGD

NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022

G

Cd4 molecule

disease_progression

mRNA:increased expression:lung (human)

RGD

NCBI chr 4:157,668,878...157,695,366

G

Cd68 molecule

disease_progression

mRNA, protein:increased expression:lung (human)
protein:increased expression:macrophage, testis (human)

RGD

PMID:19635508 PMID:16237152

RGD:5490168, RGD:27372876

NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697

G

CD9 molecule

disease_progression

mRNA, protein:increased expression:lung (human)

RGD

NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222

G

cardiotrophin-like cytokine factor 1

disease_progression

mRNA:decreased expression:lung (human)

RGD

NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605

G

C-type lectin domain family 4 member M

susceptibility
no_association

DNA:repeats:exon 4:

RGD

PMID:16369534 PMID:18708672 PMID:17534355 PMID:17534354

RGD:35673327, RGD:36049808, RGD:36049807, RGD:36049806

NCBI chr12:1,915,902...1,924,529
Ensembl chr12:1,915,919...1,924,539

G

cathepsin L

CTD Direct Evidence: marker/mechanism

PMID:16081529 PMID:16339146 PMID:22496216 PMID:23678171

NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548

G

C-X-C motif chemokine ligand 1

protein:increased expression:respiratory system fluid/secretion

RGD

NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215

G

C-X-C motif chemokine ligand 10

treatment
severity
disease_progression

protein:increased expression:serum
protein:increased expression:serum (human)
mRNA, protein: increased expression, altered expression:lung (mouse)
mRNA, protein:increased expression:serum, lung (human)
mRNA, protein:increased expression:plasma, lung (human)
protein:increased expression:lung (human)
protein:increased expression:lung (mouse)
mRNA:increased expression:lung (mouse)
mRNA:decreased expression:lung (human)

RGD

PMID:17052299 PMID:15865221 PMID:32553273 PMID:15602737 PMID:15356152 More...

RGD:5135440, RGD:33769580, RGD:32716426, RGD:32716399, RGD:30309221, RGD:30309220, RGD:30309219, RGD:30309218, RGD:30309217, RGD:30309216, RGD:30309207, RGD:5490168

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

G

C-X-C motif chemokine ligand 11

treatment

RGD

NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271

G

C-X-C motif chemokine ligand 3

mRNA:altered expression:lung (mouse)

NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511

G

C-X-C motif chemokine ligand 6

protein:increased expression:respiratory fluid/secretion

RGD

NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093

G

C-X-C motif chemokine ligand 9

severity
treatment

mRNA, protein:increased expression:lung
protein:increased expression:bronchoalveolar lavage (human)
protein:increased expression:plasma (human)
protein:increased expression:serum (human)
mRNA, protein: increased expression, altered expression:lung (mouse)

RGD

PMID:19906920 PMID:15888207 PMID:16195357 PMID:15602737 PMID:15356152 More...

RGD:4891446, RGD:34201108, RGD:30309218, RGD:32716399, RGD:30309221, RGD:30309220

NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435

G

C-X-C motif chemokine receptor 3

mRNA:altered expression:lung (mouse)

RGD

NCBI chr X:66,844,318...66,846,969
Ensembl chr X:66,844,318...66,846,969

G

epidermal growth factor receptor

severity

RGD

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

fibrinogen beta chain

protein:increased expression:lung (mouse)

RGD

NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979

G

fibroblast growth factor 7

disease_progression

mRNA:increased expression:lung (human)

RGD

NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929

G

fibrinogen gamma chain

protein:increased expression:lung (mouse)

RGD

NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322

G

fibronectin 1

protein:increased expression:lung (mouse)

RGD

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

G

follicle stimulating hormone subunit beta

protein:increased expression:adenohypophysis (human)

RGD

NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370

G

growth hormone 1

protein:decreased expression:adenohypophysis (human)

RGD

NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078

G

haptoglobin

disease_progression

mRNA:increased expression:lung (human)

RGD

NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523

G

interferon, alpha 1

CTD Direct Evidence: therapeutic

NCBI chr 5:103,097,356...103,097,925
Ensembl chr 5:103,097,356...103,097,925

G

interferon beta 1

treatment

CTD Direct Evidence: marker/mechanism|therapeutic

CTD
RGD

PMID:15200845 PMID:26861016 PMID:32553273

NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523

G

interferon gamma

susceptibility
treatment

DNA:polymorphism:cds:+874A>T(human)
protein:increased expression:peripheral blood mononuclear cells (human)
protein:increased expression:serum (human)
DNA:SNP:intron:+874A>T (rs2430561)(human)

RGD

PMID:19258635 PMID:15865221 PMID:16781892 PMID:15602737 PMID:16672072 More...

RGD:4891448, RGD:33769580, RGD:32716400, RGD:32716399, RGD:32716398, RGD:32716397, RGD:32716396

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

insulin-like growth factor 1

disease_progression

mRNA:increased expression:lung (human)

RGD

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

interleukin 10

treatment

protein:increased expression:serum, bronchoalveolar Lavage fluid (rat)

RGD

PMID:16409721 PMID:15865221

RGD:32726073, RGD:33769580

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 18

protein:increased expression:serum (human)

RGD

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 1 alpha

mRNA:altered expression:lung (mouse)

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 1 beta

severity

mRNA:altered expression:lung (mouse)
mRNA, protein:increased expression:lung, bronchoalveolar lavage (mouse)

PMID:32364527 PMID:32365944

RGD:27226699, RGD:30309207

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 1 receptor type 1

disease_progression

mRNA:increased expression:lung (human)

RGD

NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937

G

interleukin 23 subunit alpha

mRNA:decreased expression:lung (mouse)

NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923

G

interleukin 6

severity
disease_progression
treatment

protein:increased expression:serum (human)
protein:increased expression:blood (human)
protein:increased expression:bronchoalveolar lavage (human)
protein:increased expression:serum, Bronchoalveolar Lavage fluid (rat)

RGD

PMID:15657466 PMID:15472864 PMID:15888207 PMID:15865221 PMID:16409721 More...

RGD:30309219, RGD:34888224, RGD:34201108, RGD:33769580, RGD:32726073, RGD:32716426, RGD:32716401

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

interleukin 7

mRNA:decreased expression:lung (mouse)

NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075

G

interferon regulatory factor 3

disease_progression

CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (human)

CTD
RGD

PMID:26861016 PMID:19635508

NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935

G

integrin subunit alpha 2b

disease_progression

mRNA:decreased expression:lung (human)

RGD

NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168

G

keratin 7

protein:increased expression:lung (mouse)

RGD

NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052

G

luteinizing hormone subunit beta

protein:increased expression:adenohypophysis (human)

RGD

NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972

G

mitogen activated protein kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

CTD Direct Evidence: marker/mechanism

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

macrophage scavenger receptor 1

disease_progression

mRNA:increased expression:lung (human)

RGD

NCBI chr16:52,717,775...52,803,602
Ensembl chr16:52,717,732...52,799,676

G

MYD88, innate immune signal transduction adaptor

CTD Direct Evidence: marker/mechanism

NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415

G

nuclear factor, interleukin 3 regulated

disease_progression

mRNA:increased expression:lung (human)

RGD

NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858

G

NLR family, pyrin domain containing 3

RGD

NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811

G

platelet and endothelial cell adhesion molecule 1

disease_progression

mRNA, protein:increased expression:lung (human)

RGD

NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116

G

phosphatidylinositol 4-kinase beta

CTD Direct Evidence: marker/mechanism

NCBI chr 2:182,540,377...182,572,684
Ensembl chr 2:182,540,567...182,588,488

G

plasminogen activator, tissue type

protein:increased expression:plasma (human)

RGD

NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223

G

plasminogen

protein:increased expression:lung (mouse)

RGD

NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786

G

proopiomelanocortin

protein:decreased expression:adenohypophysis (human)

RGD

NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664

G

prolactin

protein:increased expression:adenohypophysis (human)

RGD

NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062

G

RAB31, member RAS oncogene family

disease_progression

mRNA:increased expression:lung (human)

RGD

NCBI chr 9:105,246,712...105,382,973
Ensembl chr 9:105,246,709...105,381,253

G

RELA proto-oncogene, NF-kB subunit

CTD Direct Evidence: marker/mechanism

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

RT1 class II, locus Da

disease_progression

mRNA:increased expression:lung

RGD

NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455

G

RT1 class II, locus Db1

DNA:polymorphism:cds:HLA-DRB1*0301 (human)
DNA:polymorphism:cds:HLA-DRB1*12 (human)

PMID:15243926 PMID:19445991

RGD:32716374 RGD:32716381

NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258

G

S100 calcium binding protein A8

disease_progression

mRNA:increased expression:lung (human)

RGD

NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643

G

serine (or cysteine) peptidase inhibitor, clade A, member 3N

protein:increased expression:plasma

RGD

NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433

G

secretory leukocyte peptidase inhibitor

disease_progression

mRNA:increased expression:lung (human)

RGD

NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453

G

signal transducer and activator of transcription 1

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

G

TANK-binding kinase 1

CTD Direct Evidence: marker/mechanism

NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892

G

transforming growth factor, beta 1

protein:increased expression:serum (human)
protein:increased expression:serum, bronchoalveolar Lavage fluid (rat)

RGD

PMID:15271897 PMID:16409721

RGD:32716401, RGD:32726073

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

G

thrombomodulin

protein:increased expression:plasma (human)

RGD

NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193

G

TIR domain containing adaptor molecule 2

CTD Direct Evidence: marker/mechanism

NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462

G

TIR domain containing adaptor protein

CTD Direct Evidence: marker/mechanism

NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432

G

toll-like receptor 2

disease_progression

mRNA:increased expression:lung (human)

RGD

NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630

G

transmembrane serine protease 11D

CTD Direct Evidence: marker/mechanism

NCBI chr14:21,707,336...21,769,398
Ensembl chr14:21,707,336...21,769,396

G

transmembrane serine protease 2

severity

RGD

NCBI chr11:36,934,306...36,973,779
Ensembl chr11:36,934,306...36,973,715

G

tumor necrosis factor

protein:increased expression:plasma (human)
protein:increased expression:bronchoalveolar lavage (human)

RGD

PMID:14514395 PMID:15888207

RGD:30309961, RGD:34201108

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

thyroid stimulating hormone subunit beta

protein:decreased expression:adenohypophysis (human)

RGD

NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559

G

vimentin

CTD Direct Evidence: marker/mechanism

NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187

G

von Willebrand factor

protein:increased expression:lung (mouse)

RGD

NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539

G

X-C motif chemokine ligand 1

mRNA:increased expression:lung (mouse)

RGD

NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329

severe COVID-19

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cholinergic receptor nicotinic alpha 5 subunit

ClinVar Annotator: match by term: Susceptibility to severe coronavirus disease (COVID-19) due to high levels of fibrinogen and C-reactive protein

PMID:18385738 PMID:18385739 PMID:18618000 PMID:19132693 PMID:19443489 More...

NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:55,369,794...55,398,146

G

interferon induced with helicase C domain 1

ClinVar Annotator: match by term: Susceptibility to severe COVID-19

PMID:25741868 PMID:28492532

NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456

G

interferon alpha and beta receptor subunit 2

ClinVar Annotator: match by term: Susceptibility to severe COVID-19

NCBI chr11:30,613,576...30,645,958
Ensembl chr11:30,613,767...30,668,124

G

lysosomal trafficking regulator

ClinVar Annotator: match by term: Susceptibility to severe COVID-19

PMID:25741868 PMID:28492532

NCBI chr17:86,241,384...86,443,501
Ensembl chr17:86,241,384...86,443,480

G

microRNA 320a

severity

miRNA:decreased expression:peripheral blood(human)

NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473

G

signal transducer and activator of transcription 2

ClinVar Annotator: match by term: Susceptibility to severe COVID-19

PMID:25741868 PMID:28492532 PMID:32135276

NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967

G

TANK-binding kinase 1

ClinVar Annotator: match by term: Susceptibility to severe COVID-19

PMID:25741868 PMID:28492532

NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892

G

TIR domain containing adaptor molecule 1

ClinVar Annotator: match by term: Susceptibility to severe COVID-19

NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147

G

toll-like receptor 4

ClinVar Annotator: match by term: Susceptibility to severe COVID-19

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

Transmissible Gastroenteritis, of Swine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATPase Na+/K+ transporting subunit alpha 1

CTD Direct Evidence: marker/mechanism

NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837

X-Linked immunodeficiency 74

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

toll-like receptor 7

ClinVar Annotator: match by term: Immunodeficiency 74, COVID-19-related, X-linked

NCBI chr X:27,027,380...27,054,309
Ensembl chr X:27,027,425...27,054,754

Term paths to the root

Path 1
Term	Annotations
disease	21128
disease by infectious agent	2214
viral infectious disease	1680
RNA Virus Infections	1400
Nidovirales Infections	1025
Coronaviridae Infections	1025
Coronavirus infectious disease	1024
COVID-19 +	948
Feline Infectious Peritonitis	0
Middle East respiratory syndrome	19
Transmissible Enteritis, of Turkeys	0
Transmissible Gastroenteritis, of Swine	1
long COVID	1
multisystem inflammatory syndrome in children	19
severe acute respiratory syndrome	87

paths to the root