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RGD uses the Human Disease Ontology (DO, for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:Zollinger-Ellison syndrome
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Accession:DOID:0050782 term browser browse the term
Definition:A syndrome that is characterized by the development of a one or more tumors (gastrinoma) in the pancreas, duodenum, or both that secrete excessive levels of gastrin, a hormone that stimulates production of acid by the stomach. (DO)
Synonyms:primary_id: MESH:D015043
 xref: GARD:7918;   ICD10CM:E16.4;   NCI:C3453
For additional species annotation, visit the Alliance of Genome Resources.

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Zollinger-Ellison syndrome term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin ISO protein:decreased expression:serum RGD PMID:908508 RGD:2325683 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Egf epidermal growth factor ISO protein:increased expression:saliva RGD PMID:10811321 RGD:2317668 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Igf1r insulin-like growth factor 1 receptor ISO mRNA and protein: increased expression::poor prognosis for high expression RGD PMID:15867218 RGD:7242847 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18156
    syndrome 9705
      Paraneoplastic Syndromes 24
        Paraneoplastic Endocrine Syndromes 4
          Zollinger-Ellison syndrome 3
Path 2
Term Annotations click to browse term
  disease 18156
    disease of anatomical entity 17531
      gastrointestinal system disease 6620
        intestinal disease 2968
          duodenum disease 93
            peptic ulcer disease 87
              Zollinger-Ellison syndrome 3
paths to the root