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EXPERIMENTAL CONDITION - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:pregnenolone 16alpha-carbonitrile
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Accession:XCO:0000845 term browser browse the term
Definition:Any condition in which the main influencing factor is pregnenolone 16alpha-carbonitrile, a catatoxic steroid that acts as an agonist of the rodent pregnane X receptor (PXR; Nr1i2).
Synonyms:exact_synonym: 3beta-hydroxy-20-oxopregn-5-ene-16alpha-carbonitrile;   C22H31NO2;   PCN
 xref: MESH:D011285;   PMID:29548889



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  experimental condition 2376
    chemical 712
      chemical with specified structure 560
        steroid 82
          pregnenolone 16alpha-carbonitrile 0
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  experimental condition 2376
    chemical 712
      chemical with specified function 517
        activator 1
          receptor agonist 1
            pregnenolone 16alpha-carbonitrile 0
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