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EXPERIMENTAL CONDITION - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:immunosuppressive agent
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Accession:XCO:0000636 term browser browse the term
Definition:This is any condition in which the main influencing factor is an agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
Synonyms:xref: CHEBI:35705



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Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Bw74 Body weight QTL 74 IDA RGD PMID:15728334 RGD:1580752 NCBI chr 3:53,184,593...115,665,732 JBrowse link
Q Bw75 Body weight QTL 75 IDA RGD PMID:15728334 RGD:1580752 NCBI chr 7:15,795,565...38,073,970 JBrowse link
Q Bw76 Body weight QTL 76 IDA RGD PMID:15728334 RGD:1580752 NCBI chr17:9,201,365...23,653,323 JBrowse link
Q Bw77 Body weight QTL 77 IDA RGD PMID:15728334 RGD:1580752 NCBI chr 3:53,184,593...64,655,484 JBrowse link
Q Bw78 Body weight QTL 78 IDA RGD PMID:15728334 RGD:1580752 NCBI chr 5:119,085,612...128,034,027 JBrowse link
Q Bw79 Body weight QTL 79 IDA RGD PMID:15728334 RGD:1580752 NCBI chr15:28,030,665...82,262,678 JBrowse link
Q Cm60 Cardiac mass QTL 60 IDA RGD PMID:15728334 RGD:1580752 NCBI chr 2:57,605,612...76,539,510 JBrowse link
Q Epfw1 Epididymal fat weight QTL 1 IDA RGD PMID:15728334 RGD:1580752 NCBI chr 3:53,184,593...115,665,732 JBrowse link
Q Epfw2 Epididymal fat weight QTL 2 IDA RGD PMID:15728334 RGD:1580752 NCBI chr 8:31,737,729...76,737,729 JBrowse link
Q Epfw3 Epididymal fat weight QTL 3 IDA RGD PMID:15728334 RGD:1580752 NCBI chr15:28,030,665...82,262,678 JBrowse link
Q Epfw4 Epididymal fat weight QTL 4 IDA RGD PMID:15728334 RGD:1580752 NCBI chr17:9,201,365...23,653,323 JBrowse link
Q Gluco24 Glucose level QTL 24 IDA RGD PMID:15728334 RGD:1580752 NCBI chr15:5,530,756...50,530,756 JBrowse link
Q Gluco25 Glucose level QTL 25 IDA RGD PMID:15728334 RGD:1580752 NCBI chr 4:85,253,748...148,090,731 JBrowse link
Q Gluco26 Glucose level QTL 26 IDA RGD PMID:15728334 RGD:1580752 NCBI chr14:73,415,323...95,876,975 JBrowse link
Q Gluco27 Glucose level QTL 27 IDA RGD PMID:15728334 RGD:1580752 NCBI chr14:73,415,323...92,554,092 JBrowse link
Q Gluco28 Glucose level QTL 28 IDA RGD PMID:15728334 RGD:1580752 NCBI chr15:28,030,665...82,262,678 JBrowse link
Q Gluco29 Glucose level QTL 29 IDA RGD PMID:15728334 RGD:1580752 NCBI chr14:73,415,323...92,554,092 JBrowse link
Q Gluco30 Glucose level QTL 30 IDA RGD PMID:15728334 RGD:1580752 NCBI chr15:28,030,665...82,262,678 JBrowse link
Q Insul10 Insulin level QTL 10 IDA RGD PMID:15728334 RGD:1580752
Q Insul6 Insulin level QTL 6 IDA RGD PMID:15728334 RGD:1580752
Q Insul7 Insulin level QTL 7 IDA RGD PMID:15728334 RGD:1580752
Q Insul8 Insulin level QTL 8 IDA RGD PMID:15728334 RGD:1580752 NCBI chr16:1...26,727,669 JBrowse link
Q Insul9 Insulin level QTL 9 IDA RGD PMID:15728334 RGD:1580752
Q Kidm30 Kidney mass QTL 30 IDA RGD PMID:15728334 RGD:1580752 NCBI chr 3:64,655,305...115,665,732 JBrowse link
Q Kidm31 Kidney mass QTL 31 IDA RGD PMID:15728334 RGD:1580752 NCBI chr 8:54,237,644...85,365,202 JBrowse link
Q Kidm32 Kidney mass QTL 32 IDA RGD PMID:15728334 RGD:1580752 NCBI chr17:9,201,365...23,653,323 JBrowse link
Q Kidm33 Kidney mass QTL 33 IDA RGD PMID:15728334 RGD:1580752 NCBI chr 1:188,377,360...224,054,420 JBrowse link
Q Kidm34 Kidney mass QTL 34 IDA RGD PMID:15728334 RGD:1580752 NCBI chr 4:148,090,542...168,069,246 JBrowse link
Q Livw1 Liver weight QTL 1 IDA RGD PMID:15728334 RGD:1580752 NCBI chr 1:155,422,851...172,949,803 JBrowse link
Q Livw2 Liver weight QTL 2 IDA RGD PMID:15728334 RGD:1580752 NCBI chr 5:99,016,066...119,085,810 JBrowse link
Q Sffal1 Serum free fatty acids level QTL 1 IDA RGD PMID:15728334 RGD:1580752 NCBI chr 7:116,677,010...124,049,952 JBrowse link
Q Sffal2 Serum free fatty acids level QTL 2 IDA RGD PMID:15728334 RGD:1580752 NCBI chr14:92,553,886...95,876,975 JBrowse link
Q Stl20 Serum triglyceride level QTL 20 IDA RGD PMID:15728334 RGD:1580752 NCBI chr 8:48,630,131...49,147,989 JBrowse link
Q Stl21 Serum triglyceride level QTL 21 IDA RGD PMID:15728334 RGD:1580752 NCBI chr15:28,030,665...82,262,678 JBrowse link
Q Sual1 Serum uric acid level QTL 1 IDA RGD PMID:15728334 RGD:1580752 NCBI chr 3:96,127,817...102,200,699 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  experimental condition 2376
    therapeutic agent 101
      immunosuppressive agent 35
        5-fluorouracil 0
        cyclophosphamide 0
        cyclosporine A 0
        dexamethasone + 35
Path 2
Term Annotations click to browse term
  experimental condition 2376
    chemical 712
      chemical with specified function 517
        immunosuppressive agent 35
          5-fluorouracil 0
          cyclophosphamide 0
          cyclosporine A 0
          dexamethasone + 35
paths to the root