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EXPERIMENTAL CONDITION - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:reserpine
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Accession:XCO:0000550 term browser browse the term
Definition:An experimental condition in which the main influencing factor is reserpine, an indole alkaloid which irreversibly blocks the vesicular monoamine transporters (VMATs), SLC18A1 and SLC18A2. Reserpine has been used as both an antihypertensive drug and an antipsychotic drug.
Synonyms:exact_synonym: Serpasil;   methyl (3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylate
 xref: CHEBI:28487;   MESH:D012110



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Related Phenotype Data for Term "reserpine" (XCO:0000550)

Rat Strains:
Clinical Measurements:
Experimental Conditions:
Measurement Methods:

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Term Annotations click to browse term
  experimental condition 2376
    chemical 707
      chemical with specified function 434
        antihypertensive agent 1
          reserpine 0
            controlled reserpine content drinking water 0
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