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EXPERIMENTAL CONDITION - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:doxorubicin
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Accession:XCO:0000539 term browser browse the term
Definition:An experimental condition in which the main influencing factor is doxorubicin, a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius and used as a chemotherapy medication. Doxorubicin binds to nucleic acids, presumably by specific intercalation of the planar anthracycline nucleus with the DNA double helix.
Synonyms:exact_synonym: ADR;   Adriablastine;   DXR;   adriamycin
 xref: CHEBI:28748


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Related Phenotype Data for Term "doxorubicin" (XCO:0000539)

Rat Strains:
Clinical Measurements:
Experimental Conditions:
Measurement Methods:
Term paths to the root
Path 1
Term Annotations click to browse term
  experimental condition 0
    therapeutic agent 0
      antineoplastic agent 0
        doxorubicin 0
          negatively charged liposome-entrapped doxorubicin 0
          positively charged liposome-entrapped doxorubicin 0
Path 2
Term Annotations click to browse term
  experimental condition 0
    chemical 0
      chemical with specified function 0
        antineoplastic agent 0
          doxorubicin 0
            negatively charged liposome-entrapped doxorubicin 0
            positively charged liposome-entrapped doxorubicin 0
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