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EXPERIMENTAL CONDITION - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:angiotensin converting enzyme inhibitor
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Accession:XCO:0000524 term browser browse the term
Definition:Any condition in which the main influencing factor is a chemical which decreases or interferes with the activity of angiotensin converting enzyme (ACE). ACE is an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. ACE inhibitors are used in the treatment of hypertension, congestive heart failure, acute myocardial infarction and diabetic nephropathy.
Synonyms:related_synonym: ACE inhibitor



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captopril term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q BpQTLcluster5 Blood pressure QTL cluster 5 IDA RGD PMID:10779487 RGD:68932 NCBI chr 4:62,933,508...114,921,294 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  experimental condition 2376
    chemical 707
      chemical with specified function 434
        antihypertensive agent 1
          angiotensin converting enzyme inhibitor 1
            Moexipril 0
            Perindopril 0
            benazepril 0
            captopril + 1
            cilazapril + 0
            delapril + 0
            enalapril + 0
            lisinopril + 0
            quinapril 0
            ramipril + 0
            temocapril 0
Path 2
Term Annotations click to browse term
  experimental condition 2376
    chemical 707
      chemical with specified function 434
        inhibitor 40
          enzyme inhibitor 34
            angiotensin converting enzyme inhibitor 1
              Moexipril 0
              Perindopril 0
              benazepril 0
              captopril + 1
              cilazapril + 0
              delapril + 0
              enalapril + 0
              lisinopril + 0
              quinapril 0
              ramipril + 0
              temocapril 0
paths to the root