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VERTEBRATE TRAIT ONTOLOGY - ANNOTATIONS

The Vertebrate Trait Ontology (VT) is being developed as a collaborative effort between the Rat Genome Database at the Medical College of Wisconsin (RGD, http://rgd.mcw.edu), Mouse Genome Informatics at the Jackson Laboratory (http://www.informatics.jax.org/) and the Animal QTL database at Iowa State University (http://www.animalgenome.org/cgi-bin/QTLdb/index). For more information about this vocabulary, or to request additions or changes, please contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:regulatory T cell morphology trait
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Accession:VT:0004941 term browser browse the term
Definition:Any measurable or observable characteristic related to the shape, structure, color, or pattern of the specialized subpopulation of T cells that act to suppress activation of the immune system and thus maintain immune system homeostasis and prevent pathological self-reactivity; these may include T cells that express the CD8 transmembrane glycoprotein (CD8-positive T cells), those that express CD4 and CD25 (CD4-positive, CD25-positive regulatory T cells or Tregs) and other T cell types that have suppressor function.
Synonyms:exact_synonym: regulatory T lymphocyte morphology trait;   suppressor T cell morphology trait;   suppressor T lymphocyte morphology trait
 narrow_synonym: Treg cell morphology trait



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Term paths to the root
Path 1
Term Annotations click to browse term
  vertebrate trait 5
    organ system trait 5
      immune system trait 0
        immune system morphology trait 0
          immune system cell morphology trait 0
            leukocyte morphology trait 0
              lymphocyte morphology trait 0
                T cell morphology trait 0
                  regulatory T cell morphology trait 0
                    CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology trait 0
                    CD8-positive, alpha-beta regulatory T cell morphology trait + 0
                    regulatory T cell quantity 0
Path 2
Term Annotations click to browse term
  vertebrate trait 5
    organ system trait 5
      hemolymphoid system trait 0
        hemolymphoid system morphology trait 0
          hematopoietic system morphology trait 0
            blood cell morphology trait 0
              leukocyte morphology trait 0
                lymphocyte morphology trait 0
                  T cell morphology trait 0
                    regulatory T cell morphology trait 0
                      CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology trait 0
                      CD8-positive, alpha-beta regulatory T cell morphology trait + 0
                      regulatory T cell quantity 0
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