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VERTEBRATE TRAIT ONTOLOGY - ANNOTATIONS

The Vertebrate Trait Ontology (VT) is being developed as a collaborative effort between the Rat Genome Database at the Medical College of Wisconsin (RGD, http://rgd.mcw.edu), Mouse Genome Informatics at the Jackson Laboratory (http://www.informatics.jax.org/) and the Animal QTL database at Iowa State University (http://www.animalgenome.org/cgi-bin/QTLdb/index). For more information about this vocabulary, or to request additions or changes, please contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).

Term:blood immunoglobulin amount
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Accession:VT:0002460 term browser browse the term
Definition:The proportion, quantity, or volume in whole blood, serum, or plasma of members of a diverse group of plasma proteins, made up of polypeptide chains, that function as a primary mechanism for protection against disease.
Synonyms:exact_synonym: blood Ig amount;   blood antibody amount
 related_synonym: immunoglobulin level;   serum level of immunoglobulin



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blood immunoglobulin A amount term browser
Symbol Object Name Evidence rsID P Value LOD Score Notes Source PubMed Reference(s) RGD Reference(s) Position
Q GWAS1234508_H anti-saccharomyces cerevisiae IgA measurement QTL GWAS1234508 (human) IAGP rs140144775 1.0E-6 GWAS_CATALOG PMID:34804013 NCBI chr 4:41,669,050...41,669,051 JBrowse link
Q GWAS1234509_H anti-saccharomyces cerevisiae IgA measurement QTL GWAS1234509 (human) IAGP rs34914463 4.0E-7 GWAS_CATALOG PMID:34804013 NCBI chr17:7,463,300...7,463,301 JBrowse link
blood immunoglobulin D amount term browser
Symbol Object Name Evidence rsID P Value LOD Score Notes Source PubMed Reference(s) RGD Reference(s) Position
Q GWAS1275127_H immunoglobulin D measurement QTL GWAS1275127 (human) IAGP rs9274697 1.0E-35 GWAS_CATALOG PMID:34648354 NCBI chr 6:32,669,239...32,669,240 JBrowse link
Q GWAS1275128_H immunoglobulin D measurement QTL GWAS1275128 (human) IAGP rs10133571 2.0E-26 GWAS_CATALOG PMID:34648354 NCBI chr14:105,825,449...105,825,450 JBrowse link
blood immunoglobulin E amount term browser
Symbol Object Name Evidence rsID P Value LOD Score Notes Source PubMed Reference(s) RGD Reference(s) Position
Q GWAS1187276_H allergic sensitization measurement QTL GWAS1187276 (human) IAGP rs1059513 1.0E-14 GWAS_CATALOG PMID:34648354 NCBI chr12:57,095,926...57,095,927 JBrowse link
Q GWAS1275282_H immunoglobulin G measurement QTL GWAS1275282 (human) IAGP rs28572080 3.0E-22 GWAS_CATALOG PMID:34648354 NCBI chr14:105,628,575...105,628,576 JBrowse link
Q GWAS1376216_H immunoglobulin E measurement QTL GWAS1376216 (human) IAGP rs369358206 2.0E-23 GWAS_CATALOG PMID:38199299 NCBI chr 6:32,652,743...32,652,744 JBrowse link
Q GWAS1376217_H immunoglobulin E measurement QTL GWAS1376217 (human) IAGP rs144651842 1.0E-16 GWAS_CATALOG PMID:38199299 NCBI chr16:27,344,903...27,344,904 JBrowse link
Q GWAS1376218_H immunoglobulin E measurement QTL GWAS1376218 (human) IAGP rs1181388 2.0E-15 GWAS_CATALOG PMID:38199299 NCBI chr 2:203,711,228...203,711,229 JBrowse link
Q GWAS1376219_H immunoglobulin E measurement QTL GWAS1376219 (human) IAGP rs365052 9.0E-15 GWAS_CATALOG PMID:38199299 NCBI chr 6:29,680,621...29,680,622 JBrowse link
Q GWAS1376220_H immunoglobulin E measurement QTL GWAS1376220 (human) IAGP rs16901848 1.0E-13 GWAS_CATALOG PMID:38199299 NCBI chr 6:28,579,175...28,579,176 JBrowse link
Q GWAS1376221_H immunoglobulin E measurement QTL GWAS1376221 (human) IAGP rs3819409 2.0E-12 GWAS_CATALOG PMID:38199299 NCBI chr 6:135,204,258...135,204,259 JBrowse link
Q GWAS1376222_H immunoglobulin E measurement QTL GWAS1376222 (human) IAGP rs112731607 1.0E-8 GWAS_CATALOG PMID:38199299 NCBI chr16:27,378,605...27,378,606 JBrowse link
Q GWAS1376223_H immunoglobulin E measurement QTL GWAS1376223 (human) IAGP rs1002957030 4.0E-8 GWAS_CATALOG PMID:38199299 NCBI chr11:112,926,911...112,926,912 JBrowse link
Q GWAS1556000_H immunoglobulin E measurement QTL GWAS1556000 (human) IAGP rs147642819 2.0E-20 GWAS_CATALOG PMID:38199299 NCBI chr 6:32,460,320...32,460,322 JBrowse link
Q GWAS1602920_H immunoglobulin G measurement QTL GWAS1602920 (human) IAGP rs4983498 1.0E-20 GWAS_CATALOG PMID:36168886 NCBI chr14:105,641,600...105,641,601 JBrowse link
Q GWAS1608214_H immunoglobulin E measurement QTL GWAS1608214 (human) IAGP rs2251746 4.0E-18 GWAS_CATALOG PMID:34648354 NCBI chr 1:159,302,270...159,302,271 JBrowse link
blood immunoglobulin G amount term browser
Symbol Object Name Evidence rsID P Value LOD Score Notes Source PubMed Reference(s) RGD Reference(s) Position
Q GWAS1158934_H IgG bisecting N-acetyl glucosamine measurement QTL GWAS1158934 (human) IAGP rs8013055 1.0E-12 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr14:105,524,283...105,524,284 JBrowse link
Q GWAS1158935_H IgG galactosylation measurement QTL GWAS1158935 (human) IAGP rs2186369 3.0E-10 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr22:23,828,809...23,828,810 JBrowse link
Q GWAS1158936_H IgG galactosylation measurement QTL GWAS1158936 (human) IAGP rs909674 2.0E-14 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr22:39,463,164...39,463,165 JBrowse link
Q GWAS1158937_H IgG sialylation measurement QTL GWAS1158937 (human) IAGP rs6421315 2.0E-8 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr 7:50,315,611...50,315,612 JBrowse link
Q GWAS1158938_H IgG sialylation measurement QTL GWAS1158938 (human) IAGP rs11135441 5.0E-10 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr 5:95,886,573...95,886,574 JBrowse link
Q GWAS1158939_H IgG sialylation measurement QTL GWAS1158939 (human) IAGP rs35590487 2.0E-12 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr14:105,523,262...105,523,263 JBrowse link
Q GWAS1158940_H IgG monogalactosylation measurement QTL GWAS1158940 (human) IAGP rs2186369 1.0E-12 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr22:23,828,809...23,828,810 JBrowse link
Q GWAS1158941_H IgG monogalactosylation measurement QTL GWAS1158941 (human) IAGP rs909674 1.0E-6 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr22:39,463,164...39,463,165 JBrowse link
Q GWAS1158942_H IgG monogalactosylation measurement QTL GWAS1158942 (human) IAGP rs6421315 3.0E-6 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr 7:50,315,611...50,315,612 JBrowse link
Q GWAS1158943_H IgG disialylation measurement QTL GWAS1158943 (human) IAGP rs909674 4.0E-14 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr22:39,463,164...39,463,165 JBrowse link
Q GWAS1158944_H IgG digalactosylation measurement QTL GWAS1158944 (human) IAGP rs2186369 4.0E-10 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr22:23,828,809...23,828,810 JBrowse link
Q GWAS1158945_H IgG digalactosylation measurement QTL GWAS1158945 (human) IAGP rs909674 3.0E-13 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr22:39,463,164...39,463,165 JBrowse link
Q GWAS1158946_H IgG digalactosylation measurement QTL GWAS1158946 (human) IAGP rs6421315 2.0E-7 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr 7:50,315,611...50,315,612 JBrowse link
Q GWAS1158947_H IgG digalactosylation measurement QTL GWAS1158947 (human) IAGP rs11135441 2.0E-9 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr 5:95,886,573...95,886,574 JBrowse link
Q GWAS1158950_H IgG fucosylation measurement QTL GWAS1158950 (human) IAGP rs11710456 1E-88 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr 3:187,008,099...187,008,100 JBrowse link
Q GWAS1158974_H IgG fucosylation measurement QTL GWAS1158974 (human) IAGP rs12342831 5.0E-13 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr 9:33,124,874...33,124,875 JBrowse link
Q GWAS1158975_H IgG fucosylation measurement QTL GWAS1158975 (human) IAGP rs2186369 3.0E-11 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr22:23,828,809...23,828,810 JBrowse link
Q GWAS1158976_H IgG fucosylation measurement QTL GWAS1158976 (human) IAGP rs909674 1.0E-20 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr22:39,463,164...39,463,165 JBrowse link
Q GWAS1158977_H IgG fucosylation measurement QTL GWAS1158977 (human) IAGP rs2659009 4.0E-11 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr17:81,239,505...81,239,506 JBrowse link
Q GWAS1158978_H IgG fucosylation measurement QTL GWAS1158978 (human) IAGP rs58087925 4.0E-19 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr14:105,516,759...105,516,760 JBrowse link
Q GWAS1158979_H IgG bisecting N-acetyl glucosamine measurement QTL GWAS1158979 (human) IAGP rs11710456 2.0E-24 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr 3:187,008,099...187,008,100 JBrowse link
Q GWAS1158980_H IgG bisecting N-acetyl glucosamine measurement QTL GWAS1158980 (human) IAGP rs2186369 4.0E-11 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr22:23,828,809...23,828,810 JBrowse link
Q GWAS1158981_H IgG bisecting N-acetyl glucosamine measurement QTL GWAS1158981 (human) IAGP rs909674 4.0E-10 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr22:39,463,164...39,463,165 JBrowse link
Q GWAS1166807_H IgG galactosylation measurement QTL GWAS1166807 (human) IAGP rs11710456 2E-90 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr 3:187,008,099...187,008,100 JBrowse link
Q GWAS1166808_H IgG galactosylation measurement QTL GWAS1166808 (human) IAGP rs12342831 7.0E-8 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr 9:33,124,874...33,124,875 JBrowse link
Q GWAS1166809_H IgG sialylation measurement QTL GWAS1166809 (human) IAGP rs2186369 1.0E-6 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr22:23,828,809...23,828,810 JBrowse link
Q GWAS1166810_H IgG sialylation measurement QTL GWAS1166810 (human) IAGP rs909674 1.0E-13 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr22:39,463,164...39,463,165 JBrowse link
Q GWAS1166811_H IgG galactosylation measurement QTL GWAS1166811 (human) IAGP rs6421315 1.0E-8 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr 7:50,315,611...50,315,612 JBrowse link
Q GWAS1166812_H IgG galactosylation measurement QTL GWAS1166812 (human) IAGP rs35590487 3.0E-18 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr14:105,523,262...105,523,263 JBrowse link
Q GWAS1166813_H IgG galactosylation measurement QTL GWAS1166813 (human) IAGP rs9319617 3.0E-9 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr17:81,218,646...81,218,647 JBrowse link
Q GWAS1166814_H IgG monogalactosylation measurement QTL GWAS1166814 (human) IAGP rs11710456 3.0E-69 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr 3:187,008,099...187,008,100 JBrowse link
Q GWAS1166817_H IgG disialylation measurement QTL GWAS1166817 (human) IAGP rs11710456 2.0E-13 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr 3:187,008,099...187,008,100 JBrowse link
Q GWAS1166818_H IgG disialylation measurement QTL GWAS1166818 (human) IAGP rs2186369 1.0E-7 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr22:23,828,809...23,828,810 JBrowse link
Q GWAS1166819_H IgG monogalactosylation measurement QTL GWAS1166819 (human) IAGP rs35590487 4.0E-17 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr14:105,523,262...105,523,263 JBrowse link
Q GWAS1166820_H IgG digalactosylation measurement QTL GWAS1166820 (human) IAGP rs11710456 5.0E-79 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr 3:187,008,099...187,008,100 JBrowse link
Q GWAS1166821_H IgG disialylation measurement QTL GWAS1166821 (human) IAGP rs6421315 3.0E-7 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr 7:50,315,611...50,315,612 JBrowse link
Q GWAS1166822_H IgG monosialylation measurement QTL GWAS1166822 (human) IAGP rs11710456 7.0E-42 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr 3:187,008,099...187,008,100 JBrowse link
Q GWAS1166823_H IgG monosialylation measurement QTL GWAS1166823 (human) IAGP rs35590487 1.0E-12 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr14:105,523,262...105,523,263 JBrowse link
Q GWAS1166824_H IgG sialylation measurement QTL GWAS1166824 (human) IAGP rs11710456 2.0E-51 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr 3:187,008,099...187,008,100 JBrowse link
Q GWAS1234502_H anti-beta-casein IgG measurement QTL GWAS1234502 (human) IAGP rs145993168 9.0E-7 GWAS_CATALOG PMID:34804013 NCBI chr 6:127,916,112...127,916,113 JBrowse link
Q GWAS1234504_H anti-feline herpes IgG measurement QTL GWAS1234504 (human) IAGP rs117760947 4.0E-7 GWAS_CATALOG PMID:34804013 NCBI chr12:129,397,670...129,397,671 JBrowse link
Q GWAS1234505_H anti-influenza A subtype H1N1 IgG measurement QTL GWAS1234505 (human) IAGP rs60526956 4.0E-7 GWAS_CATALOG PMID:34804013 NCBI chr 4:182,926,322...182,926,323 JBrowse link
Q GWAS1234506_H anti-influenza A subtype H3N2 IgG measurement QTL GWAS1234506 (human) IAGP rs58804388 2.0E-7 GWAS_CATALOG PMID:34804013 NCBI chr 2:33,385,643...33,385,644 JBrowse link
Q GWAS1234507_H anti-influenza A subtype H3N2 IgG measurement QTL GWAS1234507 (human) IAGP rs60590291 7.0E-7 GWAS_CATALOG PMID:34804013 NCBI chr10:69,498,930...69,498,931 JBrowse link
Q GWAS1299681_H IgG bisecting N-acetyl glucosamine measurement QTL GWAS1299681 (human) IAGP rs11895615 6.0E-10 Based on the EFO term ID GWAS_CATALOG PMID:33710309 NCBI chr 2:25,890,251...25,890,252 JBrowse link
Q GWAS1475311_H serum IgG glycosylation measurement QTL GWAS1475311 (human) IAGP rs11847263 5.0E-15 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr14:65,308,977...65,308,978 JBrowse link
Q GWAS1485553_H IgG galactosylation measurement QTL GWAS1485553 (human) IAGP rs116108880 8.0E-10 Based on the EFO term ID GWAS_CATALOG PMID:28878392
Q GWAS1485554_H IgG monogalactosylation measurement QTL GWAS1485554 (human) IAGP rs11847263 1.0E-17 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr14:65,308,977...65,308,978 JBrowse link
Q GWAS1485555_H IgG digalactosylation measurement QTL GWAS1485555 (human) IAGP rs11847263 3.0E-16 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr14:65,308,977...65,308,978 JBrowse link
Q GWAS1485557_H IgG monosialylation measurement QTL GWAS1485557 (human) IAGP rs11847263 6.0E-15 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr14:65,308,977...65,308,978 JBrowse link
Q GWAS1485558_H IgG fucosylation measurement QTL GWAS1485558 (human) IAGP rs11847263 6.0E-10 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr14:65,308,977...65,308,978 JBrowse link
Q GWAS1485569_H IgG galactosylation measurement QTL GWAS1485569 (human) IAGP rs11847263 1.0E-15 Based on the EFO term ID GWAS_CATALOG PMID:28878392 NCBI chr14:65,308,977...65,308,978 JBrowse link
Q GWAS1587548_H anti-beta-casein IgG measurement QTL GWAS1587548 (human) IAGP rs113530838 4.0E-7 GWAS_CATALOG PMID:34804013 NCBI chr 2:125,509,004...125,509,005 JBrowse link
Q GWAS1587549_H anti-feline herpes IgG measurement QTL GWAS1587549 (human) IAGP rs3104369 2.0E-7 GWAS_CATALOG PMID:34804013 NCBI chr 6:32,634,705...32,634,706 JBrowse link
Q GWAS1587550_H anti-feline herpes IgG measurement QTL GWAS1587550 (human) IAGP rs6509344 4.0E-7 GWAS_CATALOG PMID:34804013 NCBI chr19:47,816,228...47,816,229 JBrowse link
Q GWAS1587551_H anti-influenza A subtype H1N1 IgG measurement QTL GWAS1587551 (human) IAGP rs7256238 9.0E-7 GWAS_CATALOG PMID:34804013 NCBI chr19:51,848,370...51,848,371 JBrowse link
blood immunoglobulin M amount term browser
Symbol Object Name Evidence rsID P Value LOD Score Notes Source PubMed Reference(s) RGD Reference(s) Position
Q GWAS1273017_H immunoglobulin M measurement QTL GWAS1273017 (human) IAGP rs4813637 9.0E-25 GWAS_CATALOG PMID:34648354 NCBI chr20:3,702,115...3,702,116 JBrowse link
Q GWAS1273018_H immunoglobulin M measurement QTL GWAS1273018 (human) IAGP rs1264457 1.0E-18 GWAS_CATALOG PMID:34648354 NCBI chr 6:30,490,287...30,490,288 JBrowse link
Q GWAS1273019_H immunoglobulin M measurement QTL GWAS1273019 (human) IAGP rs149987346 2.0E-14 GWAS_CATALOG PMID:34648354 NCBI chr 3:32,416,211...32,416,217 JBrowse link
Q GWAS1273020_H immunoglobulin M measurement QTL GWAS1273020 (human) IAGP rs188468174 7.0E-12 GWAS_CATALOG PMID:34648354 NCBI chr 1:24,965,206...24,965,207 JBrowse link
Q GWAS1273021_H immunoglobulin M measurement QTL GWAS1273021 (human) IAGP rs1538970 2.0E-12 GWAS_CATALOG PMID:34648354 NCBI chr 1:45,381,890...45,381,891 JBrowse link
Q GWAS1273022_H immunoglobulin M measurement QTL GWAS1273022 (human) IAGP rs36020612 2.0E-26 GWAS_CATALOG PMID:34648354 NCBI chr11:123,473,727...123,473,728 JBrowse link
Q GWAS1608543_H immunoglobulin M measurement QTL GWAS1608543 (human) IAGP rs3018450 1.0E-25 GWAS_CATALOG PMID:34648354 NCBI chr 8:102,567,394...102,567,395 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  vertebrate trait 97071
    organism trait 54503
      homeostasis trait 23730
        blood homeostasis trait 21126
          blood molecular composition trait 18969
            blood protein amount 8756
              blood globulin amount 80
                blood immunoglobulin amount 80
                  blood autoantibody amount + 0
                  blood immunoglobulin A amount 2
                  blood immunoglobulin D amount 2
                  blood immunoglobulin E amount 13
                  blood immunoglobulin G amount + 56
                  blood immunoglobulin M amount 7
paths to the root