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CROSS-SPECIES ANATOMY - ANNOTATIONS

The Basic subset of the UBERON integrated, cross-species anatomy ontology is downloaded weekly from http://berkeleybop.org/ontologies/uberon/basic.obo. For more information about this ontology see the "About" page on the UBERON website at http://uberon.github.io/about.html.
Term:pelvic appendage apical ectodermal ridge
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Accession:UBERON:0005422 term browser browse the term
Definition:An apical ectodermal ridge that is part of a pelvic appendage bud.
Comment:[homology-note] "Pectoral and pelvic fins are homologous to the tetrapod fore and hindlimb, respectively. (...) The zebrafish AER [apical ectodermal ridge] is an apical ectodermal thickening at the distal tip of the fin bud and consists of wedge-shaped cells of the basal stratum. The AER is observed only transiently, and from 36 hpf onwards the cells of this region form the apical fold (AF), which consists of a dorsal and a ventral layer of cylindrically-shaped ectodermal cells extending from the anterior to the posterior fin margin. Despite the change in shape, the AF still carries out the same functions as the AER. Indeed, although the AER receives its name from its characteristic shape, being composed of a pseudostratified ectoderm in the chicken and a polystratified ectoderm in the mouse, this independence of AER morphology from its function is also observed in tetrapods. The AF also expresses similar molecular markers to the tetrapod AER, suggesting that it fulfills similar functions in the fin as the AER does in tetrapod limbs.[well established][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001066", ontology="VHOG", source="DOI:10.1111/j.1440-169X.2007.00942.x", source="http://bgee.unil.ch/"}
Synonyms:narrow_synonym: apical ectodermal ridge hind limb;   apical ectodermal ridge hindlimb;   lower lmb bud apical ectodermal ridge
 related_synonym: AER hindlimb;   apical ectodermal ridge pelvic fin bud;   leg AER
 xref: EFO:0003681;   EHDAA2:0003194;   EMAPA:16892;   TAO:0001385;   VHOG:0001066;   ZFA:0001385


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Term paths to the root
Path 1
Term Annotations click to browse term
  UBERON ontology 0
    anatomical entity 0
      material anatomical entity 0
        developing anatomical structure 0
          embryonic structure 0
            apical ectodermal ridge 0
              pelvic appendage apical ectodermal ridge 0
                apical ectodermal ridge pelvic fin 0
Path 2
Term Annotations click to browse term
  UBERON ontology 0
    anatomical entity 0
      material anatomical entity 0
        anatomical structure 0
          multicellular anatomical structure 0
            multicellular organism 0
              embryo 0
                embryonic structure 0
                  embryonic tissue 0
                    germ layer / neural crest 0
                      germ layer 0
                        ectoderm 0
                          ectoderm-derived structure 0
                            ecto-epithelium 0
                              pelvic appendage bud ectoderm 0
                                pelvic appendage apical ectodermal ridge 0
                                  apical ectodermal ridge pelvic fin 0
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