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CROSS-SPECIES ANATOMY - ANNOTATIONS

The Basic subset of the UBERON integrated, cross-species anatomy ontology is downloaded weekly from http://berkeleybop.org/ontologies/uberon/basic.obo. For more information about this ontology see the "About" page on the UBERON website at http://uberon.github.io/about.html.
Term:paired limb/fin bud
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Accession:UBERON:0004357 term browser browse the term
Definition:An outgrowth on the lateral trunk of the embryo that develops into a limb or paired fin. The limb/fin bud is divided into ectoderm and mesenchyme[cjm, modified from MP].
Comment:Genes: In limb buds of chick and mouse, Shh expression is activated as soon as there is a morphological bud, whereas in S. canicula fin buds, consistent with reported data in other cartilaginous fishes, Shh is transcribed late in fin development[PMID:17187056]; [homology-note] "The tetrapod limb is derived from a posterior part of the fin endoskeleton of elasmobranchs and basal bony fish, the so-called metapterygium, a series of endoskeletal elements that is the first to form in the developing paired fins. (...) In addition, there is an independent endoskeletal element called the protopterygium that develops anterior to the metapterygium in many basal fishes (e.g., the bichir and sturgeon). Teleosts have lost the metapterygium whereas the sarcopterygians, on the other hand, have lost the protopterygium. Sarcopterygians thus develop all their endoskeletal structures from the metapterygium and consequently the tetrapod limb skeleton is derived from the metapterygium.[uncertain][VHOG]" xsd:string {date_retrieved="2012-09-17", external_class="VHOG:0001258", ontology="VHOG", source="DOI:10.1002/jez.1100 Wagner GP, Chiu C, The tetrapod limb: A hypothesis on its origin. J Exp Zool (Mol Dev Evol) (2001)", source="http://bgee.unil.ch/"}
Synonyms:exact_synonym: limb - fin bud;   paired appendage bud
 xref: VHOG:0001258


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Term paths to the root
Path 1
Term Annotations click to browse term
  UBERON ontology 0
    anatomical entity 0
      material anatomical entity 0
        anatomical structure 0
          surface structure 0
            paired limb/fin bud 0
              apical ectodermal ridge + 0
              limb bud + 0
              paired fin bud + 0
              paired limb/fin + 0
              paired limb/fin bud mesenchyme + 0
              pectoral appendage bud + 0
              pelvic appendage bud + 0
Path 2
Term Annotations click to browse term
  UBERON ontology 0
    anatomical entity 0
      material anatomical entity 0
        anatomical structure 0
          multicellular anatomical structure 0
            multicellular organism 0
              embryo 0
                embryonic structure 0
                  presumptive structure 0
                    paired limb/fin bud 0
                      apical ectodermal ridge + 0
                      limb bud + 0
                      paired fin bud + 0
                      paired limb/fin + 0
                      paired limb/fin bud mesenchyme + 0
                      pectoral appendage bud + 0
                      pelvic appendage bud + 0
paths to the root